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| 1 | 青光眼患者血清抗视网膜抗原的抗体轮廓质谱分析显示文摘目的比较原发性开角型青光眼(POAG)患者与正常对照(CTRL)者间的抗体轮廓差异。方法病例对照研究。将44例POAG患者与48例CTRL者的血清分别加入到含有预洗Dyna珠-G蛋白的反应管中,以捕获人免疫球蛋白G(IgG)抗体,形成的IgG—G蛋白复合体用来捕获目标抗原(匀质化牛视网膜组织)。经洗提后获得的抗原蛋白通过“表面增强激光解吸附-电离-飞行时间-质谱”仪进行检测。采用Proteomic software project统计学软件,对两组质谱数据连同受检者年龄和性别等参数,自动进行t检验和初步多变量判别分析;随后采用Statistica version8.0统计学软件,进行包括抗原蛋白质谱数据、蛋白质芯片类型和激光解吸附-电离能量等的多变量判别分析。结果CTRL组的平均质谱强度为4244.427±4721.115,POAG组为4049.864±4083.819,两组间差异有统计学意义(F=1.340,P〈0.01);在POAG患者中,出现了部分高调节免疫反应,但主要表现为低调节免疫反应。结论在POAG患者与CTRL者之间存在明显的抗体轮廓差异,在POAG组中出现的低调节免疫反应表明部分患者可能与“异常免疫”有关。 | 严良 Joachim S. C Pfeiffer N Grus F.H Erb C | 2009 | 中华眼科杂志2009，45，7： | 3 |
| 2 | Assessment of cardiac preload and extravascular lung water by single transpulmonary thermodilution显示文摘 | SAKKA S G RUHL C C PFEIFFER U J | 2000 | Intensive Care Med2000，26，2： | 1 |
| 3 | Assessment of cardiac preload and extravascular lung water by single transpulmonary themodilution显示文摘 | SAKKA S G RUHL C C PFEIFFER U J | | 0，，02： | 1 |
| 4 | A proposal for standardization in forensic canine DNA typing: allele nomenclature of six canine-specific STR loci 显示文摘 | Hellmann AP Rohleder U Eichmann C Pfeiffer I Parson W Schleenbecker U | 2006 | Journal of Forensic Science2006，51，： | 1 |
| 5 | Long term outcome after percutaneous sclerotherapy of renal cysts with polidocanol显示文摘 | Brnken C Pfeiffer D Tauber R | | 0，，03： | 1 |
| 6 | Assessment of cardiac preload and extravascular lung water by single transpulmonary thermodilution pulmonary显示文摘 | Sakka G Ruhl C Pfeiffer J | 2000 | Intensive Care Med2000，26，2： | 1 |
| 7 | Angiotension inducs inflammatory activation of human vascular smooth muscle cells显示文摘 | KRANZHOFER R SCHMIDT J PFEIFFER C A | 1999 | Arerioscler Thromb Vasc Biol1999，19，7： | 1 |
| 8 | Video blogging:content to the max显示文摘 | Parker C Pfeiffer S | | 0，，02： | 1 |
| 9 | Long term outcome after percutaneous sclerotherapy of renal cysts with polidocanol显示文摘 | Brunken C Pfeiffer D Tauber R | | 0，，： | 1 |
| 10 | Assessment of cardiac preload and extravascular lung water by single transpulmonary themodilution 显示文摘 | Sakka S G Ruhl C C Pfeiffer U J | 2000 | Intensive Care Med2000，26，2： | 1 |
| 11 | The finn I s management of social interactions 显示文摘 | Codes D Mayzlin D Chen Y Das S Dellarocas C Pfeiffer B Libai B Sen S Shi M Verlegh P | 2005 | Marketing Letters2005，16，34： | 1 |
| 12 | A method for experimental,penetrating gastric and duodenal ulcer in rats显示文摘 | Okabe S Roth J L Pfeiffer C J | 1971 | Am J Digestive Diseases1971，16，： | 1 |
| 13 | Projection reduction exposure variable axis immersion lenses:next generation lithography显示文摘 | Pfeiffer H C | 1999 | Vac Sci Technology1999，17，1112： | 1 |
| 14 | Polyethylene parti- cle-induced bone resorption in alpha-calcitonin gene-related pep- tide-deficient mice显示文摘 | Wedemeyer C Neuerburg C Pfeiffer A | 2007 | J Bone Miner Res2007，22，7： | 1 |
| 15 | Chemotherapy for disseminated actinic keratosis with 5-fluorouracil and isotrotinoin显示文摘 | Sander CA Pfeiffer C Kligman AM | | 0，，2： | 1 |
| 16 | Flavonoid genes of pear (Pyrus communis) 显示文摘 | Fischer T C Gosch C Pfeiffer J | 2007 | Tree2007，21，： | 1 |
| 17 | Characterization of the role of ribonucleases in Salmonella small RNA decay显示文摘 | Viegas S C Pfeiffer V Sittka A | 2007 | Nucleic Acids Res2007，35，22： | 1 |
| 18 | Effects of lixisen atide once daily on gastric emptying in type 2 diabetes-relation ship to postprandial glycemia显示文摘 | Lorenz M Pfeiffer C Steinstrasser A | 2013 | Regui Pept2013，185，： | 1 |
| 19 | Complementarity problems in multibody systems with planar friction 显示文摘 | Glocker C Pfeiffer F | 1993 | Archives of Applied Mechanics1993，63，： | 1 |
| 20 | Growth and nutrition of guayule (Parthenium argentatum) in a saline soil as influ- enced by vesicular-arbuscular mycorrhiza and phosphorus fertilization显示文摘 | PFEIFFER C M BLOSS H E | 1988 | New Phytologist1988，108，3： | 1 |
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