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| 1 | How Could Agricultural Land Systems Contribute to Raise Food Production Under Global Change?显示文摘To feed the increasing world population,more food needs to be produced from agricultural land systems.Solutions to produce more food with fewer resources while minimizing adverse environmental and ecological consequences require sustainable agricultural land use practices as supplementary to advanced biotechnology and agronomy.This review paper,from a land system perspective,systematically proposed and analyzed three interactive strategies that could possibly raise future food production under global change.By reviewing the current literatures,we suggest that cropland expansion is less possible amid fierce land competition,and it is likely to do less in increasing food production.Moreover,properly allocating crops in space and time is a practical way to ensure food production.Climate change,dietary shifts,and other socio-economic drivers,which would shape the demand and supply side of food systems,should be taken into consideration during the decision-making on rational land management in respect of sustainable crop choice and allocation.And finally,crop-specific agricultural intensification would play a bigger role in raising future food production either by increasing the yield per unit area of individual crops or by increasing the number of crops sown on a particular area of land.Yet,only when it is done sustainably is this a much more effective strategy to maximize food production by closing yield and harvest gaps. | WU Wen-bin YU Qiang-yi Verburg H Peter YOU Liang-zhi YANG Peng TANG Hua-jun | 2014 | Journal of Integrative Agriculture2014，13，7： | 19 |
| 2 | miR-182参与调节胶质母细胞瘤的凋亡、生长和分化(英文)显示文摘Glioblastoma multiforme(GBM)is a lethal,therapy-resistant brain cancer consisting of numerous tumor cell subpopulations,including stem-like glioma-initiating cells(GICs),which contribute to tumor recurrence following initial response to therapy.Here,we identified miR-182 as a regulator of apoptosis,growth,and differentiation programs whose expression level is correlated with GBM patient survival.Repression of Bcl2-like12(Bcl2L12),c-Met,and hypoxia-inducible factor 2α(HIF2A)is of central importance to miR-182 anti-tumor activity,as it results in enhanced therapy susceptibility,decreased GIC sphere size,expansion,and stemness in vitro.To evaluate the tumor-suppressive function of miR-182 in vivo,we synthesized miR-182-based spherical nucleic acids(182-SNAs);i.e.,gold nanoparticles covalently functionalized with mature miR-182 duplexes.Intravenously administered 182-SNAs penetrated the bloodbrain/blood-tumor barriers(BBB/BTB)in orthotopic GBM xenografts and selectively disseminated throughout extravascular glioma parenchyma,causing reduced tumor burden and increased animal survival.Our results indicate that harnessing the anti-tumor activities of miR-182 via safe and robust delivery of 182-SNAs represents a novel strategy for therapeutic intervention in GBM. | Kouri FM Hurley LA Daniel WL Day ES Hua Y Hao L Peng CY Merkel TJ Queisser MA Ritner C Zhang H James CD Sznajder JI Chin L Giljohann DA Kessler JA Peter ME Mirkin CA Stegh AH | 2015 | 中华神经外科疾病研究杂志2015，14，2： | 14 |
| 3 | Spatio-Temporal Changes in the Rice Planting Area and Their Relationship to Climate Change in Northeast China: A Model-Based Analysis显示文摘Rice is one of the most important grain crops in Northeast China(NEC)and its cultivation is sensitive to climate change.This study aimed to explore the spatio-temporal changes in the NEC rice planting area over the period of 1980-2010 and to analyze their relationship to climate change.To do so,the CLUE-S(conversion of land use and its effects at small region extent)model was first updated and used to simulate dynamic changes in the rice planting area in NEC to understand spatio-temporal change trends during three periods:1980-1990,1990-2000 and 2000-2010.The changing results in individual periods were then linked to climatic variables to investigate the climatic drivers of these changes.Results showed that the NEC rice planting area expanded quickly and increased by nearly 4.5 times during 1980-2010.The concentration of newly planted rice areas in NEC constantly moved northward and the changes were strongly dependent on latitude.This confirmed that climate change,increases in temperature in particular,greatly influenced the shift in the rice planting area.The shift in the north limit of the NEC rice planting area generally followed a 1°C isoline migration pattern,but with an obvious time-lag effect.These findings can help policy makers and crop producers take proper adaptation measures even when exposed to the global warming situation in NEC. | XIA Tian WU Wen-bin ZHOU Qing-bo YU Qiang-yi Peter H Verburg YANG Peng LU Zhong-jun TANG Hua-jun | 2014 | Journal of Integrative Agriculture2014，13，7： | 12 |
| 4 | Laparoscopic hepatectomy by curettage and aspiration:a new technique显示文摘背景 Laparoscopic 外科为最小的侵略和快速的手术后的恢复是有益的。自从在在 1990 年代的肝切除术的 laparoscopic hepatectomy 的使用,它在有效、安全的技术的一些机构 worldwide.Lack 被执行了因为肝办理是在 1998 由刮术和渴望为 laparoscopic hepatectomy 阻止一种新技术它开发的进一步的 development.We 的主要障碍。在这份报纸,我们总共在 7 年 practice.Methods 以后分析这种技术的临床的结果 59 个连续病人在我们的机构从 1998 年 8 月由刮术和渴望经历了 laparoscopic hepatectomy 到 2005 年 1 月。这些病人包括了 33 男性和 26 女性,与 47 年的吝啬的年龄。为肝 transecsion laparoscopic, Peng 的多功能的起作用的析象器(LPMOD ) 被使用。损害在 5 .Procedures 在 19 个病人,在 17 的良性的肝肿瘤,在 18 的 intrahepatic 演算,和另外的肝损害包括了恶意的肝肿瘤在 30 个病人,的包括的本地切除术离开了在 28 的侧面的 segmentectomy,和权利在 1 个 .Results Laparoscopic 手术的 hemihepatectomy 在 57 个病人被完成。二个病人(3.4%) 把操作变换成剖腹术。吝啬的操作时间是 143 分钟,吝啬的 intraoperative 血损失是 456 mi。手术后的医院停留的吝啬的长度是 7 天。复杂并发症在 2 个病人(3.4%) 发生了,并且由刮术没有 perioperative death.Conclusion Laparoscopic hepatectomy,渴望为肝切除术有效、安全。 | CAI Xiu-jun LIANG Xiao WANG Yi-fan YU Hong ZHENG Xue-yong HUANG Di-yu PENG Shu-you Department of General Surgery,Sir Run Run Shaw Hospital,College of Medicine Institute of Minimally Invasive Surgery of Zhejiang University,Hangzhou 310016,China (Cai XJ,Liang X,Wang YF,Yu H,Zheng XY,Huang DY and Peng SY) | 2007 | Chinese Medical Journal2007，，20： | 11 |
| 5 | Interpretation of Climate Change and Agricultural Adaptations by Local Household Farmers: a Case Study at Bin County, Northeast China显示文摘Although climate change impacts and agricultural adaptations have been studied extensively,how smallholder farmers perceive climate change and adapt their agricultural activities is poorly understood.Survey-based data(presents farmers’personal perceptions and adaptations to climate change)associated with external biophysical-socioeconomic data(presents real-world climate change)were used to develop a farmer-centered framework to explore climate change impacts and agricultural adaptations at a local level.A case study at Bin County(1980s-2010s),Northeast China,suggested that increased annual average temperature(0.6°C per decade)and decreased annual precipitation(46 mm per decade,both from meteorological datasets)were correctly perceived by 76 and 66.9%,respectively,of farmers from the survey,and that a longer growing season was confirmed by 70%of them.These reasonably correct perceptions enabled local farmers to make appropriate adaptations to cope with climate change:Longer season alternative varieties were found for maize and rice,which led to a significant yield increase for both crops.The longer season also affected crop choice:More farmers selected maize instead of soybean,as implicated from survey results by a large increase in the maize growing area.Comparing warming-related factors,we found that precipitation and agricultural disasters were the least likely causes for farmers’agricultural decisions.As a result,crop and variety selection,rather than disaster prevention and infrastructure improvement,was the most common ways for farmers to adapt to the notable warming trend in the study region. | YU Qiang-yi WU Wen-bin LIU Zhen-huan Peter H Verburg XIA Tian YANG Peng LU Zhong-jun YOU Liang-zhi TANG Hua-jun | 2014 | Journal of Integrative Agriculture2014，13，7： | 8 |
| 6 | 血清netrin-1增加与缺血性脑卒中预后改善相关显示文摘先前的实验研究表明,血清netrin-1与缺血性脑卒中进展相关。进一步了解缺血性脑卒中患者中netrin-1的变化可能为缺血性脑卒中的预后评估提供新的思路。该研究旨在探讨血清netrin-1与缺血性脑卒中预后的关系。研究人员测定3346例中国急性缺血性脑卒中抗高血压试验(China antihypertensive trial in acute ischemic stroke,CATIS)中缺血性脑卒中患者基线血清netrin-1水平,所有患者均在脑卒中发病后3个月进行随访。主要观察指标是脑卒中发病后3个月内死亡和严重残疾(改良Rankin 量表评分≥3)。 | 刘莉 叶鹏 Guo D Zhu Z Zhong C Peng H Wang A Xu T Peng Y Xu T Chen CS Li Q Ju Z Geng D Chen J Zhang Y He J | 2019 | 中华高血压杂志2019，27，5： | 6 |
| 7 | Association of overexpression of TIF1γ with colorectal carcinogenesis and advanced colorectal adenocarcinoma显示文摘AIM:To determine the expression and clinical significance of transcriptional intermediary factor 1 gamma (TIF1γ),Smad4 and transforming growth factor-beta (TGFβR) across a spectrum representing colorectal cancer (CRC) development.METHODS:Tissue microarrays were prepared from archival paraffin embedded tissue,including 51 colorectal carcinomas,25 tubular adenomas (TA) and 26 HPs,each with matched normal colonic epithelium.Immunohistochemistry was performed using antibodies against TIF1γ,Smad4 and TGFβ RⅡ.The levels of expression were scored semi-quantitatively (score 0-3 or loss and retention for Smad4).RESULTS:Overexpression of TIF1γ was detected in 5/26 (19%) HP;however,it was seen in a significantly higher proportion of neoplasms,15/25 (60%) TAs and 24/51 (47%) CRCs (P<0.05).Normal colonic mucosa,HP,and TAs showed strong Smad4 expression,while its expression was absent in 22/51 (43%) CRCs.Over-expression of TGFβ RⅡ was more commonly seen in neoplasms,13/25 (52%) TAs and 29/51 (57%) CRCs compared to 9/26 (35%) HP (P<0.05).Furthermore,there was a correlation between TIF1γ overexpression and Smad4 loss in CRC (Kendall tau rank correlation value=0.35,P<0.05).The levels of TIF1γ overexpression were significantly higher in stage Ⅲ than in stage Ⅰ and Ⅱ CRC (P<0.05).CONCLUSION:The findings suggest that over-expression of TIF1γ occurs in early stages of colorectal carcinogenesis,is inversely related with Smad4 loss,and may be a prognostic indicator for poor outcome. | Shilpa Jain Shashideep Singhal Franto Francis Cristina Hajdu Jin-Hua Wang Arief Suriawinata Yin-Quan wang Miao Zhang Elizabeth H Weinshel Fritz Francois Zhi-Heng Pei Peng Lee Ru-Liang Xu | 2011 | World Journal of Gastroenterology2011，17，35： | 3 |
| 8 | Low-temperature sintering and microwave dielectric properties of Ca(Li1/3 Nb2/3)O3-δ ceramics显示文摘 | Liu Peng Kim E S Yoon K H | 2001 | Jpn Journal Application Physics2001，40，： | 2 |
| 9 | Microwave dielectric properties of low temperature sintering Ca O3-δ 显示文摘 | Liu Peng Ogawa H Kim E S | 2004 | Journal of European Ceramic Society2004，24，： | 2 |
| 10 | A study of active power filters using quad-series voltage-source PWM converters for harmonic compensation显示文摘 | Peng F Z Akagi H Nabae A | 1990 | IEEE Transactions on Power Electronics1990，5，1： | 2 |
| 11 | Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study显示文摘 | Hongjie Yu Joseph T Wu Benjamin J Cowling Qiaohong Liao Vicky J Fang Sheng Zhou Peng Wu Hang Zhou Eric H Y Lau Danhuai Guo Michael Y Ni Zhibin Peng Luzhao Feng Hui Jiang Huiming Luo Qun Li Zijian Feng Yu Wang Weizhong Yang Gabriel M Leung | 2013 | The Lancet2013，，： | 2 |
| 12 | Amino functionalized ionic liquid as an efficient and recyclable catalyst for knoevenagel reactions in water 显示文摘 | Cai Y Q Peng Y Q Song G H | 2006 | Catal Lett2006，109，： | 1 |
| 13 | Regulation of hepcidin transcription by interleukin-1 and interleukin-6显示文摘 | Lee P Peng H Gelbart T | 2005 | Proc Natl Acad Sci USA2005，102，6： | 1 |
| 14 | Theoretical studies on molecular structure and vibrational spectra of copper phthalocyanine 显示文摘 | LID C PENG Z H | 2005 | Vibrational Spectroscopy2005，39，2： | 1 |
| 15 | White spot syndrome baculovirus(WSBV) detected in cultured and captured shrimp, crabs and other arthropods 显示文摘 | Lo C F Ho C H Peng S E | 1996 | Dis Aquat Org1996，27，： | 1 |
| 16 | Neutral Pd(II) and Ni (II) aeetylide catalysts for the polymerization of methyl methaerylate 显示文摘 | SUN H M SHEN Q PENG X G | 2002 | Catalysis Letters2002，80，12： | 1 |
| 17 | Preparation and photocatalytic activity of dysprosium doped tungsten trioxide nanoparticles 显示文摘 | Liu H J Peng T Y Ke D N | 2007 | Materials Chemistry and Physics2007，104，23： | 1 |
| 18 | Loss of p12CDK2-AP1 expression in human oral squamous cell carcinoma with disrupted transforming growth factor-beta-Smad signaling pathway显示文摘 | PENG H SHINTANI S KIM Y al | 2006 | Neoplasia2006，8，： | 1 |
| 19 | A simple,rapid,high-fidelity and cost-effective PCR-based two-step DNA synthesismethod for long gene sequences显示文摘 | XIONG A S YAO Q H PENG R H | 2006 | Nucleic Acids Res2006，28，1： | 1 |
| 20 | Endothelin-1 increases expression of cyclooxygenase-2 and production of interlukin-8 in hunan pulmonary epithelial cells显示文摘 | Peng H Chen P Cai Y | 2008 | Peptides2008，29，3： | 1 |
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