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	题名	作者	年代	出处	被引量
1	Adenoma detection with cap-assisted colonoscopy versus regular colonoscopy: a randomised controlled trial显示文摘	Thomas R de Wijkerslooth Esther M Stoop Patrick M Bossuyt Elisabeth M H Mathus-Vliegen Jan Dees Kristien M A J Tytgat Monique E van Leerdam Paul Fockens Ernst J Kuipers Evelien Dekker	2012	Gut2012，，10：	3
2	Interaction between castanospermine an immunosuppressant and cyclosporin A in rat cardiac transplantation显示文摘AIM: To investigate the interaction between castanospermine and cyclosporin A(Cs A) and to provide an explanation for it.METHODS: The alkaloid castanospermine was prepared from the seeds of Castanospermum austral consistently achieving purity. Rat heterotopic cardiac transplantation and mixed lymphocyte reactivity were done using genetically inbred strains of PVG(donor) and DA(recipient). For the mixed lymphocyte reaction stimulator cells were irradiated with 3000 rads using a linear accelerator. Cyclosporin A was administered by gavage and venous blood collected 2 h later(C_2). The blood levels of Cs A(Neoral) were measured by immunoassay which consisted of a homogeneous enzyme assay(EMIT) on Cobas Mira. Statistical analyses of interactions were done by an acceleratedfailure time model with Weibull distribution for allograft survival and logistic regression for the mixed lymphocyte reactivity.RESULTS: Castanospermine prolonged transplant survival times as a function of dose even at relatively low doses. Cyclosporin A also prolonged transplant survival times as a function of dose particularly at doses above 2 mg/kg. There were synergistic interactions between castanospermine and Cs A in the prolongation of cardiac allograft survival for dose ranges of Cs A by castanospermine of(0 to 2) mg/kg by(0 to 200) mg/kg(HR = 0.986; 95%CI: 0.981-0.992; P < 0.001) and(0 to 3) mg/kg by(0 to 100) mg/kg(HR = 0.986; 95%CI: 0.981-0.992; P < 0.001) respectively. The addition of castanospermine did not significantly increase the levels of cyclosporin A on day 3 or day 6 for all doses of Cs A. On the contrary, cessation of castanospermine in the presence of Cs A at 2 mg/kg significantly increased the Cs A level(P = 0.002). Castanospermine inhibited mixed lymphocyte reactivity in a dose dependent manner but without synergistic interaction. CONCLUSION: There is synergistic interaction between castanospermine and Cs A in rat cardiac transplantation. Neither the mixed lymphocyte reaction nor the metabolism of Cs A provides an explanation.	Adrian D Hibberd David A Clark Paul R Trevillian Patrick Mcelduff	2016	World Journal of Transplantation2016，6，1：	2
3	Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘	Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys	2013	The Lancet . 2013 (9867)2013，，9867：	2
4	Substances toxic to plant-para-sitic nematodes in decomposing plant residue显示文摘	Sayre R M Patrick Z A Thorpe H	1964	Phytopathology1964，54，：	1
5	The Quality of Life (QOL) Research Movement: Past, Present, and Future显示文摘	Sirgy M A C michalos A L Ferriss R Easterlin Donald Patrick William Pavot	2006	Social Indicators Research2006，76，：	1
6	The carbon we do not see-the impact of low molecular weight compounds on carbon dynamics and respiration in forest soils:a review显示文摘	PATRICK A W DAVID L J FINLAY R	2005	Soil Biology & Biochemistry2005，37，：	1
7	Influence of extractable iron, aluminum and manganese of P sorption in flooded acid sulfate soils 显示文摘	Jugsujinda A Krairapanona A Patrick J R W H	1995	Biology and Fertility of Soils1995，20，：	1
8	COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease显示文摘	Wayne A Ray C Michael Stein James R Daugherty Kathi Hall Patrick G Arbogast Marie R Griffin	2002	The Lancet2002，，9339：	1
9	Axillary lymph node metastases in patients with a final diagnosis nf ductal carcinoma in situ显示文摘	Kelly T A Kim J A Patrick R	2003	Am J Surg2003，186，：	1
10	Simulation of hot-electron trapping andaging of nMOSFET's 显示文摘	Patrick R Samman A	1988	IEEE Trans Electron Device1988，35，12：	1
11	Bariatric surgery for type 2diabetes:weighing the impact for obesepatients显示文摘	Sangeeta R Patrick A Stacy B	2010	Cleve Clin J Med2010，7，777：	1
12	Phosphate release and sorption by soils and sediments:effect of aerobic and anaerobic conditions显示文摘	PATRICK W H J KHALID R A	1974	Science New Series1974，186，4158：	1
13	Nano-emulsion formation by emulsion phase inversion显示文摘	Valerie A Jens R	2004	Colloids and Surfaces A:Physicochemical and Engineering Aspects2004，251，13：	1
14	Clustering using a similarity measure based on shared nearest neighbors显示文摘	JARVIS R A PATRICK E A	1973	IEEE Trans on Computers : C1973，22，11：	1
15	High Pressure Phase Equilibria in the Carbon Dioxide -n -hexadecane and Carbon Dioxide - water Systems 显示文摘	D 'souza R Patrick J R Teja A S	1988	The Canadian Jour-nal of Chemical Engineering1988，66，2：	1
16	查看详情显示文摘	Schuch R Garibian A Nygaard P Raymond S Araik G Hans H S Patrick J P Per N		0，，：	1
17	Theincreasing prevalence of atrial fibrillation among hemodialysispatients显示文摘	WINKELMAYER W C PATRICK A R LIU J	2011	J Am Soc Nephrol2011，22，2：	1
18	Effect of estuarine sediment pH and oxidation-reduction potential on microbial hydrocarbon degradation 显示文摘	Hambrick G A DeLaune R D Patrick W H	1980	Appl Environ Mierobiol1980，40，2：	1
19	Clustering Using a Similarity Measure Based on Shared Nearest Neighbors显示文摘	Jarvis R A Patrick E A	1973	IEEE Trans on Computers1973，22，11：	1
20	Prognosis of pregnancy associated breast cancer显示文摘	Patrick JA Dukoff R Rogatko A	1991	Cancer1991，67，4：	1

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