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| 1 | Antidiabetic effect of Merremia emarginata Burm.F.in streptozotocin induced diabetic rats显示文摘Objective:To investigate the antidiabetic property of Merremia emarginata(M.emarginata) Burm.F.plant in streptozotocin induced diabetic rats.Methods:The dose dependent effects of 28 days oral treatment with methanol extract(100,200 and 400 mg/kg) from the plant oi M.emarginata on blood glucose level,body weight,insulin,total hemoglobin,glycosylated haemoglobin(HbA1C),total protein,serum urea,serum creatinine and carbohydrate metabolizing enzymes were evaluated in streptozotocin induced diabetic rats.Histology of pancreas was also studied.Results:A significant decrease in blood glucose,serum urea and serum creatinine and significant increase in body weight,insulin and protein level were observed in diabetic rats treated with M.emarginata.Treatment with M.emarginata resulted in a significant reduction of HbAlC and an increase in total hemoglobin level.The activities of carbohydrate metabolizing enzymes such as hexokinase were significantly increased whereas glucose-6phosphatase,fructose-1,6-bisphosphatase were significantly decreased by the administration of M.emarginata in diabetic rats.Histology of diabetic rats treated with M.emarginata showed the pancreatic β-cells regeneration.Conclusions:These findings suggest that M.emarginata has potent antidiabetic activity in streptozotocin induced diabetic rats. | G Rajiv Gandhi P Sasikumar | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 4 |
| 2 | Development of polymer electrolyte membrane fuel cell stack显示文摘 | DHATHATHREYAN K S SRIDHAR P SASIKUMAR G | 1999 | International Journal of Hydrogen Energy1999，24，11： | 1 |
| 3 | Fuzzy optimization model for water quality management of a river system显示文摘 | SASIKUMAR K MUJUMDAR P | 1998 | Journal of Water Resources Planning and Management1998，124，2： | 1 |
| 4 | Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis显示文摘 | Varma S Mahavadi P Sasikumar S Cushing L Hyland T Rosser A E | 2014 | Am J Physiol Lung Cell Mol Physiol2014，306，： | 1 |
| 5 | A Genetic Algorithm Approach for Solving a Closed Loop Supply Chain Model: A Case of Battery Recycling显示文摘 | Kannan G Sasikumar P Devika K | 2010 | Applied Mathematical Modelling2010，34，3： | 1 |
| 6 | A genetic algorithm approach for solving a closed loop supply chain model: A case of battery recycling显示文摘 | Kannan G Sasikumar P Devika K | 2010 | Applied Mathematical Model- ling2010，34，3： | 1 |
| 7 | Gap junctions and con- nexin hemichannels underpin hemostasis and thrombosis 显示文摘 | Vaiyapuri S Jones CI Sasikumar P | 2012 | Cir- culation2012，25，20： | 1 |
| 8 | Fuzzy Optimization Model for Water Quality Management of a River System 显示文摘 | Sasikumar K Mujumdar P P | 1998 | Journal of Water Re- sources Planning and Management1998，124，2： | 1 |
| 9 | Monitoring trace metal contaminants in green mussel, Perna viridis from the coastal waters of Karnataka, southwest coast of India 显示文摘 | Sasikumar G Krishnakumar P K Bhat G S | 2006 | Archives of Environmental Contamination and Toxicology2006，51，： | 1 |
| 10 | A genetic algorithm approach for solving a closed loop supply chain model: A case of battery recycling显示文摘 | KANNAN G SASIKUMAR P DEVIKA K | 2010 | Applied Mathematical Modelling2010，34，3： | 1 |
| 11 | Fuzzy Optimization Model forWater Quality Management of a River System显示文摘 | SASIKUMAR K MUJUMDAR P P | 1998 | Journal of WaterResources Planning and Management1998，124，2： | 1 |
| 12 | 查看详情显示文摘 | Chandrasekhar V Gopal K Sasikumar P | | 0，，： | 1 |
| 13 | Recognising emotions from keyboard stroke patterns显示文摘 | Khanna P Sasikumar M | | 0，，09： | 1 |
| 14 | Energetics of mechanical activation-Application to ilmenite显示文摘 | SASIKUMAR C SRIKANTH S MUKHOPADHYAY N K MEHROTRA S P | 2009 | Minerals Engineering2009，22，： | 1 |
| 15 | Fuzzy opimization model for water quality management of a river system 显示文摘 | Sasikumar K Mujumdar P P | 1998 | Journal of Water Resources Planning and Management1998，124，2： | 1 |
| 16 | 显示文摘 | Dhathathreyan K S Sridhar P Sasikumar G | 1999 | International Journal of Hydrogen Energy1999，24，11： | 1 |
| 17 | A genetic algorithm approach for solving a closed loop supply chain model: a case of battery recycling显示文摘 | Kannan G Sasikumar P Devika K | 2010 | Applied Mathematical Modelling2010，34，3： | 1 |
| 18 | Electroanalysis of some common pesticides using conducting polymer/multiwalled carbon nanotubes modified glassy carbon electrode显示文摘 | Manisankar P Abirama Sundari P L Sasikumar R | 2008 | Talanta2008，76，5： | 1 |
| 19 | Fuzzy Opimization Model for Water Quality Management of a River System 显示文摘 | SASIKUMAR K MUJUMDAR P P | 1998 | Journal of Water Resources Planning and Management1998，124，2： | 1 |
| 20 | Competition between nucleation and early growth of ferrite from austenite-studies using cellular automaton simulations显示文摘 | Kumar M Sasikumar R and Kesavan Nair P | 1998 | Acta Materialia1998，46，17： | 1 |
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