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| 1 | Selective Cytotoxic Effect of ZnO Nanoparticles on Glioma Cells显示文摘In this study we examined the cytotoxic effect of ZnO nanoparticles on various human cancer and normal cells.We found that the ZnO nanoparticles exerted a cytotoxic effect on the human glioma cell lines A172,U87,LNZ308,LN18,and LN229,whereas no cytotoxic effect was observed on normal human astrocytes.Similarly,the ZnO nanoparticles induced cell death in breast and prostate cancer cell lines while no major effect was observed in the respective normal breast and prostate cell lines.Using the fl uorescent dye 2,7-dichlorofl uorescein diacetate,we found that treatment of the glioma cells with ZnO nanoparticles induced a large increase in the generation of reactive oxygen species(ROS)and treatment of the cells with N-acetyl cysteine decreased the cytotoxic effect of the ZnO nanoparticles.In contrast,a smaller effect on ROS generation was observed in the normal astrocytes.These results suggest that ZnO nanoparticles may be employed as a selective cytotoxic agent for the eradication of cancer cells. | Stella Ostrovsky Gila Kazimirsky Aharon Gedanken Chaya Brodie | 2009 | Nano Research2009，2，11： | 5 |
| 2 | 高氮分压对碳热还原/氮化法合成氮化硅的影响显示文摘碳热还原/氮化合成氮化硅在1450-1650℃、氮气分压700-1100kPa下进行。非晶二氧化硅与石墨粉末以n(C)/n(SiO2)=4.5比率混合、压片。样品中的氧、氮、碳含量通过LECO元素分析仪测得。反应物和生成物中各物质组成通过XRD定性分析。结果表明,通过增加氮气分压,氮化硅的稳定温度升高,二氧化硅的还原速率随着温度升高而变大。碳化硅的生成仍无法避免。与常压下的碳热还原/氮化反应一致,高压下的碳化硅和氮化硅的生成亦为连续反应。 | 万小涵 张广清 John Sharp Oleg Ostrovski 俞乐 | 2015 | 有色金属工程2015，5，4： | 5 |
| 3 | Lipofuscins prepared by modification of photoreceptor cells via glycation or lipid peroxidation show the similar phototoxicity显示文摘AIM To investigate the effect of two ways of lipofuscin production(lipid peroxidation and glycation) on lipofuscin fluorescence characteristics and phototoxicity and to compare them with the properties of natural lipofuscin.METHODS Model lipofuscins were prepared on the basis of bovine photoreceptor outer segments(POS) with bisretinoid A2 E addition. One set of samples was prepared from POS modified by lipid peroxidation,while another set from POS modified by glycation with fructose. Fluorescent properties and kinetics of photoinduced superoxide generation of model lipofuscins and human retinal pigment epithelium(RPE) lipofuscin were compared. The fluorescence spectra of samples were measured at 365 nm excitation wavelength and 380-650 emission wavelength. RESULTS The fluorescence spectra of model lipofuscins are almost the same as the spectrum of natural lipofuscin. Visible light irradiation of both model lipofuscins and natural lipofuscin isolated from RPE cells leads to decrease of a fluorescence maximum at 550 nm and to appearance of a distinct,new maximum at 445-460 nm. The rate of photogeneration of reactive oxygen forms by both model lipofuscins was almost the same and approximately two times less than that of RPE lipofuscin granules.CONCLUSION These data suggest that fluorescent characteristics and phototoxicity of lipofuscin granules depend only to an insignificant degree on the oxidative modification of POS proteins and lipids,and generally are defined by the bisretinoid fluorophores contained in them. | Alexander Dontsov Anna Koromyslova Mikhail Ostrovsky Natalia Sakina | 2016 | World Journal of Experimental Medicine2016，6，4： | 3 |
| 4 | 温度对碳热还原/氮化法合成氮化硅的影响显示文摘碳热还原/氮化合成Si3N4在1300~1600℃下N2或N2-H2混合气中进行。反应物由非晶SiO2与C粉以1∶4.5摩尔比混合、压片。产生的CO由红外传感器监测,样品中氧、氮、碳含量由LECO元素分析仪测得,混合物各相由X射线衍射(XRD)检测。SiO2还原反应在1300℃以下开始,速率随温度升高增大;温度高于1570℃时,速率因反应物表面被生成物覆盖降低。由于还原产物CO平衡分压差别小,选择生成Si3N4或SiC的临界温度不明显。碳热还原/氮化法合成氮化硅的原理需进一步探讨。 | 万小涵 张广清 Oleg Ostrovski Hal Aral | 2015 | 中国工程科学2015，17，1： | 3 |
| 5 | 碳热还原/氮化合成氮化硅工艺中碳化硅生成的分析显示文摘碳热还原/氮化合成氮化硅在Si O2∶C=1∶4.5(摩尔比)、1 425-1 475℃、氮气中添加10 vol%氢气气氛、气体流量1 L/min条件下进行。生成物各相通过XRD定性分析。实验结果及热力学分析表明二氧化硅-碳-氮气反应体系中,氮化硅和碳化硅在常用温度区间内的生成趋势差别小;碳化硅成核在较高温度趋势较强,但在整个温度区间与氮化硅成核趋势均较强且差别细微;氮化硅晶体生长反应为控制步骤。在碳热还原/氮化工艺中控制Si3N4和Si C生成的边界温度并不明显,碳化硅的生成不可避免。 | 万小涵 张广清 Oleg Ostrovski | 2015 | 云南冶金2015，44，3： | 2 |
| 6 | Flexibility analysis and optimization of chemical plants with uncertain parameters显示文摘 | OSTROVSKY G M VOLIN Y M BARIT E I | 1994 | Computers & Chemical Engineering1994，18，8： | 1 |
| 7 | Evaluation of chemical processes flexibility显示文摘 | OSTROVSKY G M VOLIN Y M GOLOVASHKIN D V | 1996 | Computers Chemical Engineering1996，20，1： | 1 |
| 8 | Environmentally benign solvent design by global optimization显示文摘 | SINHA M ACHENIE L E K OSTROVSKY G M | 1999 | Computers and Chemical Engineering1999，23，： | 1 |
| 9 | On the solution of mixed-integer nonlinear programming models for computer aided molecular design显示文摘 | OSTROVSKY G M ACHENIE L E K SINHA M | 2002 | Computers & Chemistry2002，26，： | 1 |
| 10 | Fuzzy Extractor: How to Generate Strong Keys from Biometrics and Other Noisy Data显示文摘 | Dodis Y Ostrovsky R Reyzin L | 2008 | SIAM Journal on Computing2008，38，1： | 1 |
| 11 | Cross-ownership, returns, and voting in mergers 显示文摘 | Matvos G Ostrovsky M | 2008 | Journal of Financial Eco- nomics2008，89，3： | 1 |
| 12 | Chlorination of titanium oxycarbonitride produced by carbothermal nit- ridation of rutile显示文摘 | Adipuri A Zhang G Q Ostrovski O | 2009 | Industrial and Engineering Chem- istry Research2009，48，2： | 1 |
| 13 | Nonlinear internal waves in a ratating ocean显示文摘 | OSTROVSKY L A | 1978 | Okeanologia1978，18，2： | 1 |
| 14 | Searchable symmetric encryption: Improved definitions and efficient constructions显示文摘 | Reza Curtmola Juan Garay Seny Kamara Rafail Ostrovsky | 2011 | Journal of Computer Security2011，，5： | 1 |
| 15 | Nonlinear internal waves in a rotating ocean 显示文摘 | OSTROVSKY L A | 1978 | Oceanology1978，18，： | 1 |
| 16 | Retinal pigment epithelium granules stimulate the photo-oxidation of unsatureated fatty acids显示文摘 | DONTSOV A E GLICKMAN R D OSTROVSKY M A | 1999 | Free Radic Biol Med1999，26，1112： | 1 |
| 17 | Fuzzy extractors: How to generate strong keys from biometrics and other noisy data显示文摘 | DODIS Y OSTROVSKY R REYZIN L | 2008 | SIAM Journal on Computing2008，38，1： | 1 |
| 18 | Carbothermal reduction of manganese oxide in different gas atmospheres显示文摘 | KONONOV R OSTROVSKI O GANGULY S | | 0，，： | 1 |
| 19 | Effect of preoxidation and sintering on properties of ilmenite concentrates 显示文摘 | Zhang G Ostrovski O | 2002 | International Journal of Mineral Processing2002，64，4： | 1 |
| 20 | Face recognition by humans: Nineteen results all computer vision researchers should know about显示文摘 | SINHA P BALAS B OSTROVSKY Y | 2006 | Proceedings of the IEEE2006，94，11： | 1 |
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