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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | The effect of high hydrostatic pressure on strawberry flavour compounds显示文摘 | Ioannis Zabetakis Athanasios Koulentianos Estibalitz Orru?o Ian Boyes | 2000 | Food Chemistry2000，，1： | 2 |
| 3 | The reuse of abandoned Acquaresi mine voids for storage of the Masua flotation tailings显示文摘Often in abandoned mine sites are present both underground voids produced by mining and the tailings of treatment plant.An interesting solution for the rehabilitation of the sites would be to place the tailings of the process in the underground mining voids,thus obtaining the reclamation of surface areas and the stabilization of abandoned voids to prevent the dangerous phenomena of subsidence.However,these operations require inert waste,which must not be source of pollution,and the choice of a water/solid optimum to ensure good conditions of pumpability. | Pier Paolo Manca Paolo Desogus Giampaolo Orru | 2014 | International Journal of Coal Science & Technology2014，1，2： | 2 |
| 4 | Structure of pyridoxalkinase from sheep brain and role of the tryptophanyl resi-dues显示文摘 | Maras B Valiante S Orru S | 1999 | J Protein Chem1999，18，： | 1 |
| 5 | Amino acid sequence and disulfide-bridge pattern of three y-thionins from Sorghum bicolor显示文摘 | Nitti G Orru S Bloch C Jr | 1995 | Eur J Biochem1995，228，： | 1 |
| 6 | The Journal of Organic Chemistry显示文摘 | Mayer S F Steinreiber A Orru R V A Faber K | 2003 | 67(26):91152003，67，26： | 1 |
| 7 | Mechanistic investigation of the field-activated combustion synthesis ( FACS ) of titanium aluminides 显示文摘 | Orru R Cao G Munir Z A | 1999 | Chemical Engineering Science1999，54，1516： | 1 |
| 8 | SHS in Italy:An overview显示文摘 | Cao G Orru R Licheri R | 2008 | International Journal of Self-Propagating High-Temperature Synthesis2008，17，： | 1 |
| 9 | Asso-ciation analyses of single nucleotide polymorphisms in the LEP and SCD1 genes on the fatty acid profile of muscle fat in Simmental bulls显示文摘 | ORRU L CIFUNI G F PIASENTIER E | 2011 | Meat Sci2011，87，： | 1 |
| 10 | Field-activated pressure-assisted synthesis of NiTi显示文摘 | Loccia A M Orru R C ao G | 2003 | Intermetallics2003，，11： | 1 |
| 11 | Efficient technologies for the fabrication of dense TaBz-Based ultra-high-temperature显示文摘 | Licheri R Orru R Musa C | 2010 | ACS Applied Materials & Interfaces2010，2，： | 1 |
| 12 | Inter2action Proteomic显示文摘 | MariaMonti Stefania Orru Daniela Pagnozzi | 2005 | Bioscience Reports2005，，25： | 1 |
| 13 | Efficient library synthesis of imidazoles using a multicomponent reaction and microwave irradiation显示文摘 | E. Gelens F. J. J. De Kanter R. F. Schmitz L. A. J. M. Sliedregt B. J. Van Steen Chris G. Kruse R. Leurs M. B. Groen R. V. A. Orru | 2006 | Molecular Diversity2006，，1： | 1 |
| 14 | Stabilization of Nocardia EH1 epoxide hydrolase by immobilization 显示文摘 | Kroutil W Romano V A Orru V A | 1998 | Biotechnol Lett1998，20，4： | 1 |
| 15 | An Efficient Large-scale Synthesis of R-(-)-Mevalonolactone Using Simple Biological and Chemical Catalysts显示文摘 | Osprian I Kroutil W | 1998 | Synthesis1998，63，： | 1 |
| 16 | Mechanistic investigation of electric field-activated self-propagating reactions: Experimental and modeling studies 显示文摘 | Orru R Cincotti A Cao G | 2001 | Chemical Engineering Science2001，56，2： | 1 |
| 17 | Chronic caregiving stress alters peripheral blood immune parameters:the role of age and severity of stress显示文摘 | Carpiniello B Orru MG | 1997 | Psychother Psychosom1997，66，4： | 1 |
| 18 | Detection of isoniazid and rifampin resistance in mycobacterium tuberculosis strains by single-strand conformation polymorphism analysis and restriction fragment length polymorphism 显示文摘 | Piana A Orru M Masia MD | 2003 | New Microbiol2003，26，4： | 1 |
| 19 | Epoxide hydrolases and their synthetic applications 显示文摘 | Archelas A Furstoss R | 1999 | Adv Biochem Eng Biotechnol1999，63，： | 1 |
| 20 | Evaluation of antimicrobialantibiofilm activity of a hydrogen peroxide decontaminating system used in dental unit waterlines显示文摘 | Orru G Del Nero S Tuveri E | 2010 | Open Dent J2010，4，： | 1 |
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