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| 1 | Management and prevention of acute and chronic lateral ankle instability in athletic patient populations显示文摘Acute and chronic lateral ankle instability are common in high-demand patient populations. If not managed appropriately, patients may experience recurrent instability, chronic pain, osteochondral lesions of the talus, premature osteoarthritis, and other significantlong-term disability. Certain populations, including young athletes, military personnel and those involved in frequent running, jumping, and cutting motions, are at increased risk. Proposed risk factors include prior ankle sprain, elevated body weight or body mass index, female gender, neuromuscular deficits, postural imbalance, foot/ankle malalignment, and exposure to at-risk athletic activity. Prompt, accurate diagnosis is crucial, and evidence-based, functional rehabilitation regimens have a proven track record in returning active patients to work and sport. When patients fail to improve with physical therapy and external bracing, multiple surgical techniques have been described with reliable results, including both anatomic and nonanatomic reconstructive methods. Anatomic repair of the lateral ligamentous complex remains the gold standard for recurrent ankle instability, and it effectively restores native ankle anatomy and joint kinematics while preserving physiologic ankle and subtalar motion. Further preventative measures may minimize the risk of ankle instability in athletic cohorts, including prophylactic bracing and combined neuromuscular and proprioceptive training programs. These interventions have demonstrated benefit in patients at heightened risk for lateral ankle sprain and allow active cohorts to return to full activity without adversely affecting athletic performance. | Brendan J Mc Criskin Kenneth L Cameron Justin D Orr Brian R Waterman | 2015 | World Journal of Orthopedics2015，6，2： | 20 |
| 2 | CNS-PNETS分子分类中出现新的脑肿瘤实体类型显示文摘中枢神经系统原始神经外胚层肿瘤(CNS—PNET)是具有高度侵袭性分化差的胚胎性肿瘤,主要好发于幼儿,也可见于青少年和成人。 | Sturm D Orr B A Toprak U H 李晓玲 王行富 | 2016 | 临床与实验病理学杂志2016，32，7： | 16 |
| 3 | Sleep,immunity and inflammation in gastrointestinal disorders显示文摘Sleep disorders have become a global issue,and discovering their causes and consequences are the focus of many research endeavors.An estimated 70 million Americans suffer from some form of sleep disorder.Certain sleep disorders have been shown to cause neurocognitive impairment such as decreased cognitive ability,slower response times and performance detriments.Recent research suggests that individuals with sleep abnormalities are also at greater risk of serious adverse health,economic consequences,and most importantly increased all-cause mortality.Several research studies support the associations among sleep,immune function and inflammation.Here,we review the current research linking sleep,immune function,and gastrointestinal diseases and discuss the interdependent relationship between sleep and these gastrointestinal disorders.Different physiologic processes including immune system and inflammatory cytokines help regulate the sleep.The inflammatory cytokines such as tumor necrosis factor,interleukin-1(IL-1),and IL-6 have been shown to be a significant contributor of sleep disturbances.On the other hand,sleep disturbances such as sleep deprivation have been shown to up regulate these inflammatory cytokines.Alterations in these cytokine levels have been demonstrated in certain gastrointestinal diseases such as inflammatory bowel disease,gastro-esophageal reflux,liver disorders and colorectal cancer.In turn,abnormal sleep brought on by these diseases is shown to contribute to the severity of these same gastrointestinal diseases.Knowledge of these relationships will allow gastroenterologists a great opportunity to enhance the care of their patients. | Tauseef Ali James Choe Ahmed Awab Theodore L Wagener William C Orr | 2013 | World Journal of Gastroenterology2013，19，48： | 15 |
| 4 | 中国葛藤叶蝉名录及新种、新记录描述(同翅目:叶蝉科)显示文摘本文系统报道我国葛藤上的叶蝉种类 ,共有 11亚科 40属 5 0种 ,其中含 3新种、1中国新记录属、5中国新记录种 ,建立 1新组合种 ,并对折板叶蝉属ParalaevicephalusIshihara的属征进行了厘订。新种模式标本保存在安徽农业大学昆虫标本室。 | 蔡平 孙江华 江佳富 Kerry O.Britton Orr David | 2001 | 林业科学2001，37，3： | 4 |
| 5 | 腹腔镜下或胃镜下胃食管反流手术的疗效观察显示文摘目的探讨腹腔镜下或胃镜下胃食管反流(gastroesophageal reflux disease,GERD)手术的疗效、手术方法及适应证。方法总结2005年8月~2006年1月施行腹腔镜下Nissen手术52例和胃镜下胃壁折叠术28例的一般资料、手术结果,以及术后1、3个月的随访资料。结果两组的症状指数及反流时间均明显下降。腹腔镜组灼心感指数和反流指数分别从72.2±7.3和1.80±0.45下降至14.5±4.8和0.26±0.15(P均〈0.05);胃镜组该两指数分别从70.6±9.4和1.80±0.32下降至28.2±7.6和0.30±0.12(P均〈0.05)。腹腔镜组食管下段反流时间百分比从11.2%±6.2%下降至2.5%±0.4%(P〈0.05);胃镜组从10.2%±5.7%下降至7.6%±1.2%(P〈0.05)。腹腔镜手术中1例中转开腹手术,近期并发症3例,远期并发症2例,术后完全缓解率93.9%(46/49)。胃镜手术近期并发症3例,无远期并发症,术后完全缓解率58.3%(14/24)。结论腹腔镜下Nissen手术是治疗严重GERD的理想术式,胃镜下胃折叠术则适用于治疗病情轻的GERD以减少其对药物的依赖,但疗效尚待进一步提高。 | 李旭 涂远荣 Lotta Orre | 2006 | 中国微创外科杂志2006，6，10： | 4 |
| 6 | Microstructure-mechanical property relationship in hot isostatically pressed alumina and zirconia-toughened alumina 显示文摘 | Shin D W Orr K K Schubert H | 1990 | J Am Ceram Soc1990，73，5： | 2 |
| 7 | Preface to the Special Issue:Towards Improving Understanding and Prediction of Arctic Change and its Linkage with Eurasian Mid-latitude Weather and Climate显示文摘The dramatic changes in the Arctic climate system during recent decades are one of the most prominent features ofglobal climate change. Two most striking and fundamental characteristics are the amplified near-surface warming at a ratetwice the global average since the mid 20th century (e.g., Blunden and Arndt, 2012; Huang et al., 2017), and the rapiddecline of sea-ice extent at a pace of 12.9% (10 yr)-l and thinning of ice thickness by 40% since 1979 (e.g., Kwok andRothrock, 2009; Meier et al., 2012). In conjunction with these changes, the frequency of occurrence of extreme climate andweather events has ostensibly increased across the Northern Hemisphere mid-latitudes, including adverse cold spells, severeheat waves, destructive floods, and persistent droughts (e.g., Coumou and Rahmstorf, 2012). The fact that Arctic climatechanges have coincided with an increase in the frequency of occurrence of extreme events has inspired broad interest inpossible linkages--not only in the climate community, but also the general public, media agencies, and decision makers--inparticular considering the projected future continuation and acceleration of Arctic warming and sea-ice decline (e.g., Zhangand Walsh, 2006; Zhang, 2010; Stroeve et al., 2012; Wang and Overland, 2012). | Xiangdong ZHANG Thomas JUNG Muyin WANG Yong LUO Tido SEMMLER Andrew ORR | 2018 | Advances in Atmospheric Sciences2018，35，1： | 2 |
| 8 | Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing显示文摘The impact of the microenvironment on innate lymphoid cell(ILC)-mediated immunity in humans remains largely unknown.Here we used full-length Smart-seq2 single-cell RNA-sequencing to unravel tissue-specific transcriptional profiles and heterogeneity of CD127+ILCs across four human tissues.Correlation analysis identified gene modules characterizing the migratory properties of tonsil and blood ILCs,and signatures of tissue-residency,activation and modified metabolism in colon and lung ILCs.Trajectory analysis revealed potential differentiation pathways from circulating and tissue-resident naïve ILCs to a spectrum of mature ILC subsets.In the lung we identified both CRTH2+and CRTH2−ILC2 with lung-specific signatures,which could be recapitulated by alarmin-exposure of circulating ILC2.Finally,we describe unique TCR-V(D)J-rearrangement patterns of blood ILC1-like cells,revealing a subset of potentially immature ILCs with TCR-δ rearrangement.Our study provides a useful resource for in-depth understanding of ILC-mediated immunity in humans,with implications for disease. | Luca Mazzurana Paulo Czarnewski Viktor Jonsson Leif Wigge Markus Ringnér Teresa CWilliams Avinash Ravindran Åsa KBjörklund Jesper Säfholm Gunnar Nilsson Sven-Erik Dahlén Ann-Charlotte Orre Mamdoh Al-Ameri Charlotte Höög Charlotte Hedin Sylwester Szczegielniak Sven Almer Jenny Mjösberg | 2021 | Cell Research2021，31，5： | 2 |
| 9 | Perioperative Use of Dexmedetomidine Is Associated With Decreased Incidence of Ventricular and Supraventricular Tachyarrhythmias After Congenital Cardiac Operations显示文摘 | Constantinos Chrysostomou Joan Sanchez-de-Toledo Peter Wearden Edmund H. Jooste Steven E. Lichtenstein Patrick M. Callahan Tunga Suresh Elizabeth O’Malley Dana Shiderly Jamie Haney Masahiro Yoshida Richard Orr Ricardo Munoz Victor O. Morell | 2011 | The Annals of Thoracic Surgery2011，，3： | 2 |
| 10 | Jaffe-Campanacci综合征一例显示文摘患者女,10岁。因摔伤后右上肢疼痛、肿胀、活动受限15 d,四肢正侧位X线片发现多发骨破坏,于2010年10月20日人院。既往6年前曾因右下肢活动无力行有下肢及右肱骨正侧位X线片检查后,诊断为“右肱骨、有股骨非骨化性纤维瘤”。并行肿瘤刮除植骨术治疗。体检:患者智力正常,全身软组织内未触及明确包块。脊柱无侧凸。右上肢有压痛、外展痛阳性。 | 周玉华 毕丽荣 王晶波 王银萍 William Orr | 2011 | 中华病理学杂志2011，40，6： | 2 |
| 11 | Nitrio oxide during perfusion improves posttransplantation function of on-heart-beation donor lungs 显示文摘 | AITCHISON J D ORR H E FLECKNELL P A | 2003 | Transplantation2003，75，12： | 1 |
| 12 | Status report on the NBME's computer -based Testing显示文摘 | Orr NA | 1990 | Acad Med1990，65，3： | 1 |
| 13 | BLyS:member of the tumor necrosis factor family and B lymp-hocyte stimulator显示文摘 | Moore PA Belvedere O Orr A | 1999 | Science1999，285，10： | 1 |
| 14 | The Determinants of Entry: A Study of the Canadian Manufacturing Industries 显示文摘 | Orr Dale | 1974 | Review of Economics and Statistics1974，56，1： | 1 |
| 15 | Data quality and systems theory 显示文摘 | Orr K | 1998 | Communications of the ACM1998，41，2： | 1 |
| 16 | Health benefits ofTai Chi for older patients with type 2 diabetes: The 'Move It for Diabetes Study' - A randomized controlled trial 显示文摘 | Tracey Tsang Rhonda Orr Paul Lain Elizabeth J Comino | 2007 | Clinical Interventions in Aging2007，2，3： | 1 |
| 17 | A model of the demand for money by firms显示文摘 | Miller Merton and Daniel Orr | 1966 | Quarterly Journal of Economics1966，80，： | 1 |
| 18 | Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine显示文摘 | Ireson CR Jones DJ Orr S | 2002 | Cancer Epidemiol Biomarkers Prev2002，11，1： | 1 |
| 19 | Thermodynamic functions of iron 显示文摘 | Orr R L Chipman J | 1967 | Trans AIME1967，239，： | 1 |
| 20 | Analytical calculation of minimum miscibility pressure显示文摘 | Wang Y Orr F M | 1997 | Fluid Phase Equilibria1997，，139： | 1 |
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