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| 1 | Mediterranean diet and nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) is emerging as the most common chronic liver disease, and is characterized by a wide spectrum of fat-liver disorders that can result in severe liver disease and cirrhosis. Inflammation and oxidative stress are the major risk factors involved in the pathogenesis of NAFLD. Currently, there is no consensus concerning the pharmacological treatment of NAFLD. However, lifestyle interventions based on exercise and a balanced diet for quality and quantity, are considered the cornerstone of NAFLD management. Mediterranean diet(MD), rich in polyunsaturated fats, polyphenols, vitamins and carotenoids, with their anti-inflammatory and antioxidant effects, has been suggested to be effective in preventing cardiovascular risk factors. In adults, MD has also been demonstrated to be efficacious in reducing the risk of metabolic syndrome. However, few studies are available on the effects of the MD in both adult and pediatric subjects with NAFLD. Thus, the aims of the present narrative review are to analyze the current clinical evidence on the impact of MD in patients with NAFLD, and to summarize the main mechanisms of action of MD components on this condition. | Caterina Anania Francesco Massimo Perla Francesca Olivero Lucia Pacifico Claudio Chiesa | 2018 | World Journal of Gastroenterology2018，24，19： | 19 |
| 2 | TRPV1 may increase the effectiveness of estrogen therapy on neuroprotection and neuroregeneration显示文摘Aging induces physical deterioration,loss of the blood brain barrier,neuronal loss-induced mental and neurodegenerative diseases.Hypotalamus-hypophysis-gonad axis aging precedes symptoms of menopause or andropause and is a major determinant of sensory and cognitive integrated function.Sexual steroids support important functions,exert pleiotropic effects in different sensory cells,promote regeneration,plasticity and health of the nervous system.Their diminution is associated with impaired cognitive and mental health and increased risk of neurodegenerative diseases.Then,restoring neuroendocrine axes during aging can be key to enhance brain health through neuroprotection and neuroregeneration,depending on the modulation of plasticity mechanisms.Estrogen-dependent transient receptor potential cation channel,subfamily V,member 1(TRPV1) expression induces neuroprotection,neurogenesis and regeneration on damaged tissues.Agonists of TRPV1 can modulate neuroprotection and repair of sensitive neurons,while modulators as other cognitive enhancers may improve the survival rate,differentiation and integration of neural stem cell progenitors in functional neural network.Menopause constitutes a relevant clinical model of steroidal production decline associated with progressive cognitive and mental impairment,which allows exploring the effects of hormone therapy in health outcomes such as dysfunction of CNS.Simulating the administration of hormone therapy to virtual menopausal individuals allows assessing its hypothetical impact and sensitivity to conditions that modify the effectiveness and efficiency. | Ricardo Ramírez-Barrantes Ivanny Marchant Pablo Olivero | 2016 | Neural Regeneration Research2016，11，8： | 5 |
| 3 | Immune response to vaccines in children with celiac disease显示文摘Celiac disease(CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and HLA-DQ8 haplotypes, and enteropathy. Vaccination is the most potent intervention for infectious disease prevention. Several factors including age, gender, ethnicity, quality and quantity of vaccine antigen, doses, and route of administration can influence immune response to vaccination, although the main cause of variation in the responsiveness among vaccine recipients is host genetic variability. The HLA system has a fundamental role in identifying the antigens introduced into the host with the vaccines and in the development of specific antibodies, and some HLA phenotypes have been associated with a less effective immunological response. The available literature indicates that the immunological response to vaccines in CD children does not differ markedly from that of general population and antibody titres are high enough to provide long-term protection, except for hepatitis B virus vaccine. In this article, we review and discuss the scarce literature in this field in order to provide clinical practice guidelines to achieve the most efficient monitoring of the response to vaccines in pediatric CD patients. | Caterina Anania Francesca Olivero Alessandra Spagnolo Claudio Chiesa Lucia Pacifico | 2017 | World Journal of Gastroenterology2017，23，18： | 2 |
| 4 | Photo- chemical processes for water-treatment显示文摘 | LEGRINI O OLIVEROS E BRAUN A M | 1993 | Chemical Reviews1993，93，2： | 1 |
| 5 | A pilot study on physical training of patients in hemodialysis显示文摘 | Oliveros RMS Avendano Ms Bunout D | 2011 | Rev Med Chil2011，139，8： | 1 |
| 6 | Expression of the Met/hepatocyte growth factor receptor in human pancrearic cancer 显示文摘 | Di Renzo MF Poulsom R Olivero M | 1995 | Cancer Res1995，55，： | 1 |
| 7 | Phenotype variants malignancy,additional copies of 6p in retinoblastoma显示文摘 | CANO J OLIVEROS O YUNIS E | 1994 | Cancer Genet Cytogenet1994，76，： | 1 |
| 8 | Overexpression of the MET/HGF receptor in ovarian cancer 显示文摘 | DI RENZO M F OLIVERO M KATSAROS D | 1994 | Int J Cancer1994，58，5： | 1 |
| 9 | 3D sequence interpretation of seismic instantaneous attributes from the Gorgon field 显示文摘 | Radovich B J Oliveros R 13 | 1998 | The Leading Edge1998，17，9： | 1 |
| 10 | Advanced oxidation processes for organic contaminant destruction based on the Fenton reaction and related chemistry 显示文摘 | PIGNATELLO J J OLIVEROS E MACKAY A | 2006 | Crit Rev Environ Sci Technol2006，36，1： | 1 |
| 11 | Expression of the Met/HGF receptor in normal and neoplastic human tissues 显示文摘 | Di Renzo MF Narsimhan RP Olivero M | 1991 | Oncogen1991，6，11： | 1 |
| 12 | Electronic nose based on metal oxide semiconductor sensors as a fast ahemative for the detection of adulteration of virgin olive oils显示文摘 | Cerrato Oliveros M C P 6 rez Pav 6 n J L Garca Pinto C | 2002 | Analytica Chimica Acta2002，459，2： | 1 |
| 13 | Outcome of chronic delta hepatitis in Italy: A long-term cohort study显示文摘 | Grazia Anna Niro Antonina Smedile Antonio Massimo Ippolito Alessia Ciancio Rosanna Fontana Antonella Olivero Maria Rosa Valvano Maria Lorena Abate Domenica Gioffreda Gian Paolo Caviglia Mario Rizzetto Angelo Andriulli | 2010 | Journal of Hepatology2010，，5： | 1 |
| 14 | New evidence against hydroxyl radicals as reactive intermediates in the thermal and photochemically enhanced Fenton reaction显示文摘 | BOSSMANN S H OLIVEROS E GOB S | 1998 | J Phys Chem A1998，102，28： | 1 |
| 15 | Photochemical processes for water treatment 显示文摘 | Legrini O Oliveros E Braun A M | 1993 | Chemical Reviews1993，93，： | 1 |
| 16 | Calcium modulates osmosensitive taurine efflux in HeLa cells显示文摘 | Olivero P Stutzin A | 2004 | Neurochem Res2004，29，1： | 1 |
| 17 | Protective immune response to foot-and-mouth disease virus with VP1 expressed in transgenic plants显示文摘 | Carrillo C Wigdorovitz A Oliveros J C | 1998 | J Virol1998，72，2： | 1 |
| 18 | CD34+ cell enumeration in peripheral blood and apheresis samples,using two laboratory diagnostic kits or an institutional protocol显示文摘 | Olivero S Alario T Ladaique P | 1999 | Bone Marrow Transplant1999，23，： | 1 |
| 19 | Type 1V collagen, laminin, and fibronectin promote the adhesion and migration of rabbit lens epithelial cells in vitro显示文摘 | Olivero DK Furcht LT | 1993 | Invest Ophthalmol Vis Sci1993，34，10： | 1 |
| 20 | Deactivation kinetics and response surface analysis of the stability of α-L-Rhamnosidase from penicillium decumbens 显示文摘 | Magario I Neumann A Oliveros E | 2009 | Appl Biochem Biotechnol2009，，152： | 1 |
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