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| 1 | A Snapshot of the Effective Indications and Results of Surgery for Hepatocellular Carcinoma in Tertiary Referral Centers: Is It Adherent to the EASL/AASLD Recommendations?: An Observational Study of the HCC East-West Study Group显示文摘 | Guido Torzilli Jacques Belghiti Norihiro Kokudo Tadatoshi Takayama Lorenzo Capussotti Gennaro Nuzzo Jean-Nicolas Vauthey Michael A. Choti Eduardo De Santibanes Matteo Donadon Emanuela Morenghi Masatoshi Makuuchi | 2013 | Annals of Surgery2013，，5： | 7 |
| 2 | Intraoperative use of indocyanine green fluorescence imaging in rectal cancer surgery: The state of the art显示文摘Indocyanine green(ICG)fluorescence imaging is widely used in abdominal surgery.The implementation of minimally invasive rectal surgery using new methods like robotics or a transanal approach required improvement of optical systems.In that setting,ICG fluorescence optimizes intraoperative vision of anatomical structures by improving blood and lymphatic flow.The purpose of this review was to summarize all potential applications of this upcoming technology in rectal cancer surgery.Each type of use has been separately addressed and the evidence was investigated.During rectal resection,ICG fluorescence angiography is mainly used to evaluate the perfusion of the colonic stump in order to reduce the risk of anastomotic leaks.In addition,ICG fluorescence imaging allows easy visualization of organs such as the ureter or urethra to protect them from injury.This intraoperative technology is a valuable tool for conducting lymph node dissection along the iliac lymphatic chain or to better identifying the rectal dissection planes when a transanal approach is performed.This is an overview of the applications of ICG fluorescence imaging in current surgical practice and a synthesis of the results obtained from the literature.Although further studies are need to investigate the real clinical benefits,these findings may enhance use of ICG fluorescence in current clinical practice and stimulate future research on new applications. | Roberto Peltrini Mauro Podda Simone Castiglioni Maria Michela Di Nuzzo Michele D'Ambra Ruggero Lionetti Maurizio Sodo Gaetano Luglio Felice Mucilli Salomone Di Saverio Umberto Bracale Francesco Corcione | 2021 | World Journal of Gastroenterology2021，27，38： | 3 |
| 3 | Influence of surgical margin on type of recurrence after liver resection for colorectal metastases:a single-center experience显示文摘 | Nuzzo G Ciuliante F Ardilo F | | 0，，03： | 2 |
| 4 | Metastatic pancreatic cancer: Is there a light at the end of the tunnel?显示文摘Due to extremely poor prognosis,pancreatic cancer(PDAC)represents the fourth leading cause of cancerrelated death in Western countries.For more than a decade,gemcitabine(Gem)has been the mainstay of first-line PDAC treatment.Many efforts aimed at improving single-agent Gem efficacy by either combining it with a second cytotoxic/molecularly targeted agent or pharmacokinetic modulation provided disappointing results.Recently,the field of systemic therapy of advanced PDAC is finally moving forward.Polychemotherapy has shown promise over single-agent Gem:regimens like PEFG-PEXG-PDXG and GTX provide significant potential advantages in terms of survival and/or disease control,although sometimes at the cost of poor tolerability.The PRODIGE 4/ACCORD 11 was the first phaseⅢtrial to provide unequivocal benefit using the polychemotherapy regimen FOLFIRINOX;however the less favorable safety profile and the characteristics of the enrolled population,restrict the use of FOLFIRINOX to young and fit PDAC patients.The nanoparticle albumin-bound paclitaxel(nab-Paclitaxel)formulation was developed to overcome resistance due to the desmoplastic stroma surrounding pancreatic cancer cells.Regardless of whether or not this is its main mechanisms of action,the combination of nabPaclitaxel plus Gem showed a statistically and clinically significant survival advantage over single agent Gem and significantly improved all the secondary endpoints.Furthermore,recent findings on maintenance therapy are opening up potential new avenues in the treatment of advanced PDAC,particularly in a new era in which highly effective first-line regimens allow patients to experience prolonged disease control.Here,we provide an overview of recent advances in the systemic treatment of advanced PDAC,mostly focusing on recent findings that have set new standards in metastatic disease.Potential avenues for further development in the metastatic setting and current efforts to integratenew effective chemotherapy regimens in earlier stages of disease(neoadjuvant,adjuvant,and multimodal approaches in both resectable and unresectable patients)are also briefly discussed. | Vanja Vaccaro Isabella Sperduti Sabrina Vari Emilio Bria Davide Melisi Carlo Garufi Carmen Nuzzo Aldo Scarpa Giampaolo Tortora Francesco Cognetti Michele Reni Michele Milella | 2015 | World Journal of Gastroenterology2015，21，16： | 2 |
| 5 | Relationship between Chlamydia pneumoniae infection, inflammatory markers, and coronary heart diseases显示文摘 | ROMANO CARRATELLI C NUZZO I COZZOLINO D | 2006 | Int Immunopharmacol2006，6，： | 1 |
| 6 | Evolutionary limits ameliorate the negative impact of an invasive plant 显示文摘 | LANKAU R A NUZZO V SPYREAS G | 2009 | Proceedings of the National Academy of Sciences USA2009，106，15： | 1 |
| 7 | Bone effect of adjuvant tamoxifen, letrozole or letrozole plus zoledronic acid in early-stage breast cancer: the randomized phase 3 HOBOE study 显示文摘 | Nuzzo F Gallo C Lastoria S | 2012 | Ann Oneol2012，23，8： | 1 |
| 8 | Chronic kidney disease may be differentially diagnosed from preeclampsia by serum biomarkers显示文摘 | Rolfo A Attini K Nuzzo AM | 2013 | Kidney Int2013，83，1： | 1 |
| 9 | Disease persistence in patients with cervical intraepithelial neoplasia undergoing electrosurgical conization显示文摘 | Costa S Nuzzo MD Infante FE | 2002 | Gynecologic Oncology2002，85，1： | 1 |
| 10 | The risk of biliary ductal injury during laparoscopic cholecystectomy显示文摘 | Nuzzo G Giuliante F Persiani R | 2004 | J Chir (Paris)2004，141，6： | 1 |
| 11 | Metabolic syndrome affects cardiovascular risk profile and response to treatment in hypertensive postmenopausul women显示文摘 | Rossi R Nuzzo A Oriqliani G | 2008 | Hypertension2008，52，5： | 1 |
| 12 | Bile duct injury during laparoscopic cholecystectomy:resuhs of an Italian National Survey on 56 591 cholecystectomies 显示文摘 | Nuzzo G Giuliante F Giovannini I | 2005 | Arch Surg2005，140，10： | 1 |
| 13 | Management of the controversial aspects of the antiphospholipid syndrome pregnancies:aguide for clinicians and researchers显示文摘 | Erkan D Patel S Nuzzo M | 2008 | Rheumatology(Oxford)2008，473，： | 1 |
| 14 | Molecular pharmacodynamics of new oral drugs used in the treatment of multiple sclerosis显示文摘 | Di Nuzzo L Orlando R Nasca C | 2014 | Drug Des Devel Ther2014，8，： | 1 |
| 15 | Bile duct injury during laparoscopic cholecystectomy:results of an Italian national survey on 56 591 cholecystectomies显示文摘 | Nuzzo G Giuliante F Giovannini I | | 0，，10： | 1 |
| 16 | Liver resection for primarily unresectable colorectal metastases downsized by chemotherapy 显示文摘 | Nuzzo G Giuliante F Ardito F | 2007 | J Gastrointest Surg2007，11，3： | 1 |
| 17 | Synthesis, assem bly and applications of semiconductor nanomembranes显示文摘 | Rogers J A Lagally M G Nuzzo R G | 2011 | Nature2011，477，： | 1 |
| 18 | Pathophysiologic and clinical correlates of hypophosphatemia and the relationship with sepsis and outcome in postoperative patients after hepatectomy 显示文摘 | Giovannini I Chiarla C Nuzzo G | 2002 | Shock2002，18，2： | 1 |
| 19 | A descriptive study of lower body strength and power in overweight adolescents显示文摘 | NUZZO J L CAVILL M J TRIPLETT N T | | 0，，： | 1 |
| 20 | Extraparenchymal Control of Hepatic Veins During Mesohepatectomy显示文摘 | Felice Giuliante Gennaro Nuzzo Francesco Ardito Maria Vellone Germano De Cosmo Ivo Giovannini | 2008 | Journal of the American College of Surgeons2008，，3： | 1 |
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