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| 1 | 三种工农业废料的理化性状及作为蘑菇覆土材料的研究显示文摘分析测定了纸厂废渣、蘑菇废料和香菇废料等3种工农业废料的理化性状,并以这3种废料作覆土材料,研究其对蘑菇生长与产量的影响。结果表明,纸厂废渣、蘑菇废料和香菇废料的持水率分别为49.3%,43.8%和70.7%,均高于砻糠田土(33%),但低于泥碳(84.5%)。3种废料的电导率及pH值均高于砻糠田土和泥碳。香菇废料和蘑菇废料具有与泥碳相似的水分释放曲线,在1.7×104Pa的牵力下,香菇废料和泥碳的水分释出量相近,分别达87.25ml和92.35ml,而蘑菇废料的水分释出量相对较低,为58.25ml。纸厂废渣的水分释放曲线与砻糠田土相似。以这3种工农业废料作蘑菇覆土材料,蘑菇产量均明显高于以砻糠田土作覆士材料,增幅分别为11.7%,32.0%和21.1%。 | 蔡为明 Ralph Noble 金群力 方菊莲 冯伟林 范丽军 | 2002 | 浙江农业学报2002，14，6： | 18 |
| 2 | The role of Toll-like receptors in non-infectious lung injury显示文摘在病原体识别的像使用费的受体(TLR ) 的角色在最近的年里是快速地先进的。然而,进在非传染的织物损害的 TLR 的功能的调查刚开始了。以前,我们和其它表明了那碎裂的 hyaluronan (哈) 在织物损害期间积累。CD44 被要求在织物损害期间清除 HA,并且损害了清理哈在不停的发炎的结果。另外,碎裂哈在损害地点由煽动性的房间刺激煽动性的基因的表示。最近,我们识别了那哈碎片要求 TLR2 和 TLR4 刺激老鼠巨噬细胞生产煽动性的 chemokines 和 cytokines。在一个非传染的肺损害模型,在 TLR2 和 TLR4 缺乏的老鼠显示出煽动性的房间的损害 transepithelial 迁居,增加的织物损害,提高的肺上皮的房间 apoptosis,和减少的幸存。在高分子的质量的表示上的肺上皮的房间哈对尖锐的肺损害和 apoptosis 的保护的老鼠,部分地通过 NF-kappaB 的 TLR 依赖的基础激活。在 TLR2 和 TLR4 的夸大的损害缺乏的老鼠看起来由于上皮的房间上的损害 HA-TLR 相互作用。这些研究识别那个主机矩阵部件哈并且 TLR 相互作用提供开始煽动性的回答的信号,维持上皮的房间完整,并且支持从尖锐的肺损害的恢复。房间研究(2006 ) 16:693-701。做 i:10.1038/sj .cr.7310085;出版联机 2006 年 8 月 8 日。 | Dianhua Jiang Jiurong Liang Yuhang Li Paul W Noble | 2006 | Cell Research2006，16，8： | 16 |
| 3 | 孕前血压及其到妊娠早期的变化:先兆子痫和妊娠期高血压的早期危险因素显示文摘先兆子痫和妊娠期高血压是常见的妊娠并发症,与母婴发病率显著相关。尽管对怀孕期间的危险因素进行了广泛的研究,但大多数患妊娠期高血压疾病的妇女并不被认为是高风险的,预防措施仍不清楚。研究者评估了妊娠前的血压及其到妊娠早期的变化,将其作为妊娠高血压疾病发展新的危险标志。 | 刘青(译) 刘莉(摘/审校) Nobles CJ Mendola P Mumford SL Silver RM Kim K Andriessen VC Connell M Sjaarda L Perkins NJ Schisterman EF | 2020 | 中华高血压杂志2020，28，12： | 12 |
| 4 | Two new species of Japalura(Squamata:Agamidae)from the Hengduan Mountain Range,China显示文摘Until recently,the agamid species,Japalura flaviceps,was recognized to have the widest geographic distribution among members of the genus occurring in China,from eastern Tibet to Shaanxi Province.However,recent studies restricted the distribution of J.flaviceps to the Dadu River valley only in northwestern Sichuan Province,suggesting that records of J.flaviceps outside the Dadu River valley likely represent undescribed diversity.During two herpetofaunal surveys in 2013 and 2015,eight and 12 specimens of lizards of the genus Japalura were collected from the upper Nujiang(=Salween)Valley in eastern Tibet,China,and upper Lancang(=Mekong)Valley in northwestern Yunnan,China,respectively.These specimens display a unique suite of diagnostic morphological characters.Our robust comparisons of phenotype reveal that these populations can be distinguished readily from J.flaviceps and all other recognized congeners.Herein,we describe the two Japalura lineages as new species,Japalura laeviventris sp.nov.and Japalura iadina sp.nov..In addition,we provide updated conservation assessments for the new species as well as imperiled congeners according to the IUCN criteria for classification,discuss the importance of color patterns in the diagnosis and description of species in the genus Japalura,and discuss directions for future taxonomic studies of the group. | Kai WANG Ke JIANG Da-Hu ZOU Fang YAN Cameron D.SILER Jing CHE Kunming Institute of Zoology,Chinese Academy of Sciences Sam Noble Oklahoma Museum of Natural History and Department of Biology,University of Oklahoma Tibet University | 2016 | Zoological Research2016，37，1： | 9 |
| 5 | Development of Magnesium-Dominant Soils Under Irrigated Agriculture in Southern Kazakhstan显示文摘Irrational irrigation practices in the Arys Turkestan Canal command area in the southern part of Kazakhstan have led to the formation of soils with poor physical and chemical properties. To study whether irrigation and leaching practices and/or groundwater rise have contributed to the accumulation of Mg2+ on the cation exchange complex of these soils, historical changes in soil and groundwater quality were used as source data and the Visual MINTEQ model was applied to analyze the chemical composition of water and soils in the study area. The imposed irrigation regime and the leaching of light sierosem soils led to the dissolution and subsequent leaching of inherent gypsum and organic matter from the soil profile. Further, the domination of bicarbonate in the irrigation water promoted weathering of the carbonate minerals present as calcite. The higher concentrations of Mg2+ in comparison to Ca2+ in the irrigation water resulted in the replacement of Na+ by Mg2+ on the cation exchange complex. In the lower part of the command area, shallow groundwater has contributed to the accumulation of Na+ and to a large extent of Mg2+ on the cation exchange sites. | A. KARIMOV M. QADIR A. NOBLE F. VYSHPOLSKY K. ANZELM | 2009 | Pedosphere2009，19，3： | 9 |
| 6 | A review of state-of-the-art processing operations in coal preparation显示文摘Coal preparation is an integral part of the coal commodity supply chain. This stage of post-mining,pre-utilization beneficiation uses low-cost separation technologies to remove unwanted mineral matter and moisture which hinder the value of the coal product. Coal preparation plants typically employ several parallel circuits of cleaning and dewatering operations, with each circuit designed to optimally treat a specific size range of coal. Recent innovations in coal preparation have increased the efficiency and capacity of individual unit operations while reinforcing the standard parallel cleaning approach. This article,which describes the historical influences and state-of-the-art design for the various coal preparation unit operations, is organized to distinguish between coarse/intermediate coal cleaning and fine/ultrafine coal cleaning. Size reduction, screening, classification, cleaning, dewatering, waste disposal unit operations are particularly highlighted, with a special focus on the U.S. design philosophy. Notable differences between the U.S. and international operations are described as appropriate. | Noble Aaron Luttrell Gerald H. | 2015 | International Journal of Mining Science and Technology2015，25，4： | 7 |
| 7 | 优质双孢蘑菇堆肥的现代堆制模式显示文摘本文从现代双孢蘑菇堆肥的配方 ,一次发酵的堆制程序 ,二次发酵技术和相关的一些重要理化指标等方面简要地介绍了优质蘑菇堆肥的现代堆制模式和方法 ,从而阐明现代堆制模式比传统方式的优越性。 | 李荣春 Ralph Noble | 2001 | 中国食用菌2001，20，1： | 7 |
| 8 | 多器官床旁即时超声在新型冠状病毒肺炎中的应用:国际专家共识显示文摘新型冠状病毒肺炎(简称新冠肺炎,COVID-19)自首次报道以来,已造成全球超一亿人感染,给各国的公共卫生体系造成了巨大威胁。新冠肺炎的临床表现以呼吸系统体征和症状为主,80%的患者症状轻微,约5%为危重症患者,常表现为急性呼吸窘迫综合征(ARDS)。前期,由于缺乏相关研究,面对日益紧迫的临床困境,医务人员不得不借鉴采取一些经验性措施以应对疫情。 | 王臻(译) Arif Hussain Gabriele Via Lawrence Melniker Alberto Goffi Guido Tavazzi Luca Neri Tomas Villen Richard Hoppmann Francesco Mojoli Vicki Noble Laurent Zieleskiewicz Pablo Blanco Irene W.Y.Ma Mahathar Abd.Wahab Abdulmohsen Alsaawi Majid AI Salamah Martin Balik Diego Barca Karim Bendjelid Belaid Bouhemad Pablo Bravo-Figueroa Raoul Breitkreutz Juan Calderon Jim Connolly Roberto Copetti Francesco Corradi Anthony J.Dean AndréDenault Deepak Govil Carmela Graci Young-Rock Ha Laura Hurtado Toru Kameda Michael Lanspa Christian B Laursen Francis Lee Rachel Liu Massimiliano Meineri Miguel Montorfano Peiman Nazerian Bret P.Nelson Aleksandar N.Neskovic Ramon Nogue Adi Osman JoséPazeli Elmo Pereira-Junior Tomislav Petrovic Emanuele Pivetta Jan Poelaert Susanna Price Gregor Prosen Shalim Rodriguez Philippe Rola Colin Royse Yale Tung Chen Mike Wells Adrian Wong Wang Xiaoting Wang Zhen Yaseen Arabi | 2021 | 中国呼吸与危重监护杂志2021，20，2： | 5 |
| 9 | A new genus and species of treefrog from Medog,southeastern Tibet,China(Anura,Rhacophoridae)显示文摘A new genus and species of threefrog is described from Medog,southeastern Tibet,China based on morphological and phylogenetic data.The new genus can be distinguished from other treefrog genera by the following combination of characters:(1)body size moderate,45.0 mm in male;(2)snout rounded;(3)canthus rostralis obtuse and raised prominently,forming a ridge from nostril to anterior corner of eyes;(4)web rudimentary on fingers;(5)web moderately developed on toes;(6)phalange 'Y' shaped,visible from dorsal side of fingers and toes;(7)skin of dorsal surfaces relatively smooth,scatted with small tubercles;(8)iris with a pale yellow,'X' shaped pattern of pigmentation. | Ke JIANG Fang YAN Kai WANG Da-Hu ZOU Cheng LI Jing CHE State Key Laboratory of Genetic Resources and Evolution,Kunming Institute of Zoology,Chinese Academy of Sciences Sam Noble Oklahoma Museum of Natural History and Department of Biology,University of Oklahoma Tibet University Imaging Biodiversity Expedition | 2016 | Zoological Research2016，37，1： | 5 |
| 10 | 双孢蘑菇生活史的多样性显示文摘野生双孢蘑菇在形态、生态、生理、遗传等方面具有广泛的多样性。大部分野生和栽培的双孢蘑菇菌株和品种具有次级同宗配合的性特征,也有少数野生菌株属于异宗配合的类型。通过对采自英国牛津的野生双孢蘑菇菌株96.4的单孢菌株的形态、生长、交配、结实、RAPD和AFLP遗传标记等方面研究的分析,发现该菌株具有次级同宗配合和异宗配合的双重交配方式,成为独立的一群。研究表明野生双孢蘑菇在生活史方面具有丰富的多样性。 | 李荣春 Ralph Noble | 2005 | 云南农业大学学报2005，20，3： | 5 |
| 11 | Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus显示文摘AIM:To assess tumour regression grade(TRG)and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS:Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal junction treated with surgery alone or neoadjuvant chemotherapy and surgery between 2005and 2011 at a single institution were reviewed.Triplet neoadjuvant chemotherapy consisting of platinum,fluoropyrimidine and anthracycline was considered for operable patients(World Health Organization performance status≤2)with clinical stage T2-4 N0-1.Response to neoadjuvant chemotherapy(NAC)was assessed using TRG,as described by Mandard et al.In addition lymph node downstaging was also assessed.Lymph node downstaging was defined by cN1 at diagnosis:assessed radiologically(computed tomography,positron emission tomography,endoscopic ultrasonography),then pathologically recorded as N0 after surgery;ypN0 if NAC given prior to surgery,or pN0if surgery alone.Patients were followed up for 5 years post surgery.Recurrence was defined radiologically,with or without pathological confirmation.An association was examined between t TRG and lymph node downstaging with disease free survival(DFS)and a comprehensive range of clinicopathological characteristics.RESULTS:Two hundred and eighteen patients underwent esophageal resection during the study interval with a mean follow up of 3 years(median follow up:2.552,95%CI:2.022-3.081).There was a 1.8%(n=4)inpatient mortality rate.One hundred and thirty-six(62.4%)patients received NAC,with 74.3%(n=101)of patients demonstrating some signs of pathological tumour regression(TRG 1-4)and 5.9%(n=8)having a complete pathological response.Forty four point one percent(n=60)had downstaging of their nodal disease(cN1 to ypN0),compared to only 15.9%(n=13)that underwent surgery alone(pre-operatively overstaged:cN1 to pN0),(P<0.0001).Response to NAC was associated with significantly increased DFS(mean DFS;TRG 1-2:5.1years,95%CI:4.6-5.6 vs TRG 3-5:2.8 years,95%CI:2.2-3.3,P<0.0001).Nodal down-staging conferred a significant DFS advantage for those patients with a poor primary tumour response to NAC(median DFS;TRG 3-5 and nodal down-staging:5.533 years,95%CI:3.558-7.531 vs TRG 3-5 and no nodal down-staging:1.114 years,95%CI:0.961-1.267,P<0.0001).CONCLUSION:Response to NAC in the primary tumour and in the lymph nodes are both independently associated with improved DFS. | Fergus Noble Luke Nolan Adrian C Bateman James P Byrne Jamie J Kelly Ian S Bailey Donna M Sharland Charlotte N Rees Timothy J Iveson Tim J Underwood Andrew R Bateman | 2013 | World Journal of Gastroenterology2013，19，48： | 4 |
| 12 | The Australasian frog family Ceratobatrachidae in China,Myanmar and Thailand:discovery of a new Himalayan forest frog clade显示文摘In an effort to study the systematic affinities and specieslevel phylogenetic relationships of the enigmatic anurans variably assigned to the genera Ingerana or Limnonectes(family Dicroglossidae),we col ected new molecular sequence data for five species including four Himalayan taxa,Limnonectes xizangensis,Lim.medogensis,Lim.alpina,Ingerana borealis and one southeast Asian species,I.tasanae,and analyzed these together with data from previous studies involving other ostensibly related taxa.Our surprising results demonstrate unequivocal y that Lim.xizangensis,Lim.medogensis and Lim.alpina form a strongly supported clade,the sister-group of the family Australasian forest frog family Ceratobatrachidae.This discovery requires an expansion of the definition of Ceratobatrachidae and represents the first record of this family in China.These three species are distinguished from the species of Ingerana and Limnonectes by the:(1)absence of interdigital webbing of the foot,(2)absence of termina discs on fingers and toes,(3)absence of circumargina grooves on the fingers and toes,and(4)absence of tarsal folds.Given their phylogenetic and morphologica distinctiveness,we assign them to the oldest available generic name for this clade,Liurana Dubois 1987,and transfer Liurana from Dicroglossidae to the family Ceratobatrachidae.In contrast,Ingerana tasanae was found to be clustered with strong support with the recently described genus Alcalus(Ceratobatrachidae),asmall clade of otherwise Sundaic species;this constitutes a new record of the family Ceratobatrachidae for Myanmar and Thailand.Final y,Ingerana borealis clustered with the 'true' Ingerana(family Dicroglossidae),for which the type species is I.tenasserimensis. | Fang YAN Ke JIANG Kai WANG Jie-Qiong JIN Chatmongkon SUWANNAPOOM Cheng LI Jens V.VINDUM Rafe M.BROWN Jing CHE State Key Laboratory of Genetic Resources and Evolution,Kunming Institute of Zoology,Chinese Academy of Sciences Southeast Asia Biodiversity Research Institute,Chinese Academy of Sciences Sam Noble Oklahoma Museum of Natural History and Department of Biology,University of Oklahoma School of Agriculture and Natural Resources,University of Phayao Imaging Biodiversity Expedition Department of Herpetology,California Academy of Sciences Biodiversity Institute and Department of Ecology and Evolutionary Biology,1345 Jayhawk Blvd,University of Kansas | 2016 | Zoological Research2016，37，1： | 4 |
| 13 | Enhancement of biogas potential of primary sludge by co-digestion with cow manure and brewery sludge显示文摘Anaerobic digestion(AD)has long been used to treat different types of organic wastes especially in the developed world.However,organic wastes are still more often considered as a waste instead of a resource in the developing world,which contributes to environmental pollution arising from their disposal.This study has been conducted at Bugolobi Sewage Treatment Plant(BSTP),where two organic wastes,cow manure and brewery sludge were co-digested with primary sludge in different proportions.This study was done in lab-scale reactors at mesophilic temperature and sludge retention time of 20 d.The main objective was to evaluate the biodegradability of primary sludge generated at BSTP,Kampala,Uganda and enhance its ability of biogas production.When the brewery sludge was added to primary STP sludge at all proportions,the biogas production rate increased by a factor of 3.This was significantly(p<0.001)higher than observed gas yield(337±18)mL/(L·d))in the control treatment containing(only STP sludge).Co-digesting STP sludge with cow manure did not show different results compared to the control treatment.In conclusion,Bugolobi STP sludge is poorly anaerobically degradable with low biogas production but co-digestion with brewery sludge enhanced the biogas production rate,while co-digestion with cow manure was not beneficial. | Irene Nansubuga Noble Banadda Mohammed Babu Jo De Vrieze Willy Verstraete Korneel Rabaey | 2015 | International Journal of Agricultural and Biological Engineering2015，8，4： | 4 |
| 14 | Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation显示文摘 | Jasmohan S. Bajaj Phillip B. Hylemon Jason M. Ridlon Douglas M. Heuman Kalyani Daita Melanie B. White Pamela Monteith Nicole A. Noble Masoumeh Sikaroodi Patrick M. Gillevet | 2012 | AJP: Gastrointestinal and Liver Physiology2012，，6： | 3 |
| 15 | Novel susceptibility genes in inflammatory bowel disease显示文摘The inflammatory bowel disease, Crohn's disease and ulcerative colitis, are polygenic disorders with important environmental interactions. To date, the most widely adopted approach to identifying susceptibility genes in complex diseases has involved genome wide linkage studies followed by studies of positional candidate genes in loci of interest. This review encompasses data from studies into novel candidate genes implicated in the pathogenesis of inflammatory bowel disease. Novel techniques to identify candidate genes-genome wide association studies, yeast-two hybrid screening, microarray gene expression studies and proteomic profiling, are also reviewed and their potential role in unravelling the pathogenesis of inflammatory bowel disease are discussed. | Colin Noble Elaine Nimmo Daniel Gaya Richard K Russell Jack Satsangi | 2006 | World Journal of Gastroenterology2006，12，13： | 3 |
| 16 | Management of advanced non-small-cell lung cancer, the potential role of gemcitabine显示文摘 | Noble S Faulds D | 1999 | Health Outcomes1999，5，3： | 3 |
| 17 | Colonoscopy quality with Entonox? vs intravenous conscious sedation:18608 colonoscopy retrospective study显示文摘AIM To compare colonoscopy quality with nitrous oxide gas(Entonox?) against intravenous conscious sedation using midazolam plus opioid.METHODS A retrospective analysis was performed on a prospectively held database of 18608 colonoscopies carried out in Lothian health board hospitals between July 2013 and January 2016.The quality of colonoscopies performed with Entonox was compared to intravenous conscious sedation(abbreviated in this article as IVM).Furthermore,the quality of colonoscopies performed with an unmedicated group was compared to IVM.The study used the following key markers of colonoscopy quality:(1) patient comfort scores;(2) caecal intubation rates(CIRs); and (3) polyp detection rates (PDRs).We used binary logistic regression to model the data.RESULTS There was no difference in the rate of moderate-toextreme discomfort between the Entonox and IVM groups (17.9% vs 18.8%; OR = 1.06,95%CI: 0.95-1.18,P = 0.27).Patients in the unmedicated group were less likely to experience moderate-to-extreme discomfort than those in the IVM group(11.4% vs 18.8%; OR = 0.71,95%CI: 0.60-0.83,P < 0.001).There was no difference in caecal intubation between the Entonox and IVM groups(94.4% vs 93.7%; OR = 1.08,95%CI: 0.92-1.28,P = 0.34).There was no difference in caecal intubation between the unmedicated and IVM groups (94.2% vs 93.7%; OR = 0.98,95%CI: 0.79-1.22,P = 0.87).Polyp detection in the Entonox group was not different from IVM group (35.0% vs 33.1%; OR = 1.01,95%CI: 0.93-1.10,P = 0.79).Polyp detection in the unmedicated group was not significantly different from the IVM group (37.4% vs 33.1%; OR = 0.97,95%CI: 0.87-1.08,P = 0.60).CONCLUSION The use of Entonox was not associated with lower colonoscopy quality when compared to intravenous conscious sedation using midazolam plus opioid. | Alexander R Robertson Nicholas A Kennedy James A Robertson Nicholas I Church Colin L Noble | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 3 |
| 18 | BIM应用于体育建筑设计研究——国内外案例分析显示文摘相关软件公司开发了大量适用于当代BIM技术的辅助设计程序,每个软件都有各自的特点,而对于体育建筑设计,需要综合考虑项目自身特点选择设计软件。使用BIM软件不仅仅是一种图纸化的手段,还可以帮助设计师从新的角度去思考建筑设计的方法。 | 段文婷 Karen Kensek Douglas Noble | 2013 | 建筑技艺2013，，2： | 3 |
| 19 | Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice显示文摘Oral 4-aminopyridine(4-AP)is clinically used for symptomatic relief in multiple sclerosis and we recently demonstrated that systemic 4-AP had previously unknown clinically-relevant effects after traumatic peripheral nerve injury including the promotion of re-myelination,improvement of nerve conductivity,and acceleration of functional recovery.We hypothesized that,instead of oral or injection administration,transdermal 4-AP(TD-4-AP)could also improve functional recovery after traumatic peripheral nerve injury.Mice with surgical traumatic peripheral nerve injury received TD-4AP or vehicle alone and were examined for skin permeability,pharmacokinetics,functional,electrophysiological,and nerve morphological properties.4-AP showed linear pharmacokinetics and the maximum plasma 4-AP concentrations were proportional to TD-4-AP dose.While a single dose of TD-4-AP administration demonstrated rapid transient improvement in motor function,chronic TD-4-AP treatment significantly improved motor function and nerve conduction and these effects were associated with fewer degenerating axons and thicker myelin sheaths than those from vehicle controls.These findings provide direct evidence for the potential transdermal applicability of 4-AP and demonstrate that 4-AP delivered through the skin can enhance in-vivo functional recovery and nerve conduction while decreasing axonal degeneration.The animal experiments were approved by the University Committee on Animal Research(UCAR)at the University of Rochester(UCAR-2009-019)on March 31,2017. | Andrew RClark Chia George Hsu M A Hassan Talukder Mark Noble John CElfar | 2020 | Neural Regeneration Research2020，15，1： | 3 |
| 20 | Modulation of the fecal bile acid profile by gut microbiota in cirrhosis显示文摘 | Genta Kakiyama William M. Pandak Patrick M. Gillevet Phillip B. Hylemon Douglas M. Heuman Kalyani Daita Hajime Takei Akina Muto Hiroshi Nittono Jason M. Ridlon Melanie B. White Nicole A. Noble Pamela Monteith Michael Fuchs Leroy R. Thacker Masoumeh Sikaro | 2013 | Journal of Hepatology2013，，5： | 3 |
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