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91篇 您的检索式:作者名="Niewold"
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1Acute phase reaction and acute phase proteins显示文摘A review of the systemic acute phase reaction with major cytokines involved, and the hepatic metabolic changes, negative and positive acute phase proteins (APPs) with function and associated pathology is given. It appears that APPs represent appropriate analytes for assessment of animal health. Whereas they represent non-specific markers as biological effect reactants, they can be used for assessing nutritional deficits and reactive processes, especially when positive and negative acute phase variables are combined in an index. When such acute phase index is applied to separate healthy animals from animals with some disease, much better results are obtained than with single analytes and statistically acceptable results for culling individual animals may be reached. Unfortunately at present no cheap, comprehensive and easy to use system is available for assessing various acute phase proteins in serum or blood samples at the same time. Protein microarray or fluid phase microchip technology may satisfy this need; and permit simultaneous analysis of numerous analytes in the same small volume sample and enable integration of information derived from systemic reactivity and nutrition with disease specific variables. Applying such technology may help to solve health problems in various countries not only in animal husbandry but also in human populations.GRUYS E. TOUSSAINT M.J.M. NIEWOLD T.A. KOOPMANS S.J. 2005Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2005,6,11:13
2Plasma intestinal fatty acid binding protein (Ⅰ-FABP) concentrations increase following intestinal ischemia in pigs显示文摘Niewold TA Meinen M van der Meulen J 0,,01:1
3Genetic regulation of serum cytokines in systemic lupus erythematosus 显示文摘Kariuki SN Niewold TB 2010Transl Res2010,155,3:1
4Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus显示文摘Ritterhouse LL Crowe SR Niewold TB 2011Ann Rheum Dis2011,70,9:1
5Interferon regulatory factors in human lupus pathogenesis显示文摘Salloum R Niewold TB 2011Transl Res2011,157,6:1
6Clinical characteristics of patients with anti-Jo-1 antibodies:a single center experience显示文摘Mileti LM Strek ME Niewold TB 0,,05:1
7Dietary specific antibodies in spray-dried immune plasma prevent enterotoxigenic Escherichia coli F4 (ETEC) post weaning diarrhoea in piglets显示文摘Niewold T A van Dijk A J Geenen P L 2007Veterinary Microbiology2007,124,34:1
8Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumstoid arthritis 显示文摘Niewold T B Harrison M J Paget S A 2007QJM2007,100,4:1
9Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematsus显示文摘Ritterhouse LL Crowe SR Niewold TB 2011Ann Rheum Dis2011,70,9:1
10Vitamin D deficiency is associated with an increased autoimmune re- sponse in healthy individuals and in patients with system- ic lupus erythematosus显示文摘Ritterhouse LL Crowe SR Niewold TB 2011Ann Rheum Dis2011,70,9:1
11Small intestinal morphology and disaccharidase ac- tivities in early-weaned piglets fed a diet containing spray-dried porcine plasma显示文摘VAN DIJK A J NIEWOLD T A NABUURS M J 2002J Vet Med A Physiol Pathol Clin Med2002,49,2:1
12A loss-of-function variant of the antiviral molecule MAVS is associated with a subset of systemic lupus patients 显示文摘Pothlichet J Niewold TB Vitour D 2011EMBO Mol Med2011,3,3:1
13Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumatoid arthritis显示文摘Niewold T B Harrison M J Paget S A 2007Q J Med2007,100,19:1
14Genetic regulation of serum cytokines in systemic lupus erythematosus显示文摘Kariuki SN Niewold TB 2010Transl Res2010,155,3:1
15Vitamin D deficiency is associated with an increased auto-immune response in healthy individuals and in patientswith systemic lupus erythematosus 显示文摘RITTERHOUSE L L CROWE S R NIEWOLD TB 2011Ann Rheum Dis2011,70,9:1
16Augmented interferon-alpha pathway activation in patients with Sjogren's syn- drome treated with etanercept 显示文摘Mavragani C P Niewold T B Moutsopoulos N M 2007Arthritis Rheum2007,56,12:1
17Sirukumab : a novel therapy for lupus nephritis? 显示文摘Thanarajasingam U Niewold TB 2014Expert Opin Investig Drugs2014,23,10:1
18Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumatoid arthritis 显示文摘Niewold T B Harrison M J Paget S A 2007QJM2007,100,4:1
19Interferon alpha-induced lupus:proof of principle显示文摘Niewold TB 0,,03:1
20Age-and sex-related patternsserum interferon-αactivity in lupus families显示文摘Niewold TB Adler JE Glenn SE 2008Arthritis&Rheumatism2008,58,7:1
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