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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Major outer membrane proteins of Brucella spp.: past, present and future显示文摘 | Axel Cloeckaert Nieves Vizca??no Jean-Yves Paquet Raúl A Bowden Philip H Elzer | 2002 | Veterinary Microbiology2002，，1： | 2 |
| 3 | Colloidal Stability of Polymer Colloids with Variable Surface Charge 显示文摘 | PUERTAS A M NIEVES F J D L | 1999 | Journal ofColloid and Interface Science1999，216，2： | 1 |
| 4 | Effects of daily treatment with parathyroid hormone on bone microarchitecture and turnover in patients with osteoporosis:a paired biopsy study显示文摘 | Dempster DW Cosman F Kurland ES Zhou H Nieves J Woelfert L Shane E Plavetic K Muller R Bilezikian J Lindsay R | | 0，，10： | 1 |
| 5 | Feasibility of an electronic nose to differentiate commercial Spanish wines elaborated from the same grape variety显示文摘 | María de las Nieves López de Lerma Andrea Bellincontro Teresa García-Martínez Fabio Mencarelli Juan José Moreno | 2013 | Food Research International2013，，2： | 1 |
| 6 | Major outer membrane proteins of Brucella spp.: past, present and future显示文摘 | Axel Cloeckaert Nieves Vizca??no Jean-Yves Paquet Raúl A Bowden Philip H Elzer | 2002 | Veterinary Microbiology2002，，1： | 1 |
| 7 | A phase Ⅱ trial of weekly 1 - hour paclitaxelas second - line therapy for endometrial and cervical cancer 显示文摘 | Homesley HD Meltzer NP Nieves L | 2008 | Int J Clin 0ncol2008，13，1： | 1 |
| 8 | Enhanced T-cell immu- nity to osteosarcoma through antibody blockade of PD-1/PD-L1 interactions显示文摘 | Lussier DM (YNeill L Nieves LM | 2015 | J Immunother2015，38，3： | 1 |
| 9 | Recovering spec- tral scenes with an RGB and colored filters data from natural dig- ital camera显示文摘 | Valero E M Nieves J L Nascimento S | 2007 | Color Research and Application2007，32，5： | 1 |
| 10 | Cost-reduction analysis for oral versus intravenous fludarabine (Beneflur) in Spain显示文摘 | Delgado J Febrer L Nieves D | 2009 | Farm Hosp2009，33，5： | 1 |
| 11 | Catalyt- ic role of conserved HQGE motif in the CE6 carbohydrate esterase family显示文摘 | NIEVES L C DOLORES R D BELOQUI A | 2007 | FEBS Letters2007，581，24： | 1 |
| 12 | Parathyroid hormone added to established hormone therapy:effects on vertebral fracture and maintenance of bone mass after PTH withdrawal显示文摘 | Cosman F Nieves J Woelfert L et a1 | 2001 | J Bone Miner Res2001，16，： | 1 |
| 13 | Multispectral Sysnthesis of Daylight Using a Commercial Digital CCD Camera 显示文摘 | Nieves J L Valero E M Nascimento S M C | 2005 | The Journal of Optical Society of America2005，44，27： | 1 |
| 14 | Linear bases for spectral reflectance functions of acrylic paints显示文摘 | García-Beltrán A Nieves J L Hernández-Andrés J | 1998 | Color Research&Application1998，，23： | 1 |
| 15 | Advances in ethanol production显示文摘 | Geddes C C Nieves I U Ingram L O | 2011 | Current Opinion in Biotechnolo-gy2011，22，3： | 1 |
| 16 | A phase II thai of weekly 1-hour paclitaxel as second-line therapy for endometrial and cervical cancer显示文摘 | Homesley HD Meltzer NP Nieves L | 2008 | Int J Clin Oneo12008，13，1： | 1 |
| 17 | BASKETBALL SCORING IN NBA GAMES:AN EXAMPLE OF COMPLEXITY显示文摘Scoring in a basketball game is a highly dynamic,non-linear process.NBA teams try to be more and more competitive each season.For instance,they incorporate into their rosters the best players in the world.This and other mechanisms concur to make the scoring process in NBA games exciting and rarely predictable.This paper is to study the behavior of timing and scoring in basketball games.The authors analyze all the games in five NBA regular seasons(2005-06,2006-07,2007-08,2008-09,2009-10),for a total of 6150 games.Scoring does not behave uniformly;therefore,the authors also analyze the distributions of the differences in points in the basketball games.To further analyze the behavior of the tail of the distribution,the authors also carry out a semilog-plot and a log-log plot to verify whether this trend approaches a Poisson distribution or a PL.This paper reveals different areas of behavior related to the score,with specific instances of time that could be considered tipping points of the game.The presence of these critical points suggests that there are phase transitions where the dynamic scoring of the games varies significantly. | DE SA GUERRA Yves MARTíN GONZALEZ Juan Manuel SARMIENTO MONTESDEOCA Samuel RODRIGUEZ RUIZ David ARJONILLA LóPEZ Nieves GARCíA-MANSO Juan Manuel | 2013 | Journal of Systems Science & Complexity2013，26，1： | 1 |
| 18 | Parathyroid hormone added to established hormone therapy: effects on vertebral fracture and maintenance of bone mass after parathyroid hormone withdrawal显示文摘 | COSMAN F NIEVES J WOELFERT L | 2001 | J Bone Miner Res2001，16，5： | 1 |
| 19 | Parathyroid hormone added to established hormone therapy: effects on vertebral fracture and maintenance of bone mass a{ter parathyroid hormone withdrawal显示文摘 | COSMAN F NIEVES J WOELFERT L | 2001 | J Bone Miner Res2001，16，5： | 1 |
| 20 | Parathyroid hormone added to established hormone therapy:effects on vertebral fracture and maintenance of bone mass after parathyroid hormone withdrawal显示文摘 | Cosman F Nieves J Woelfert L | 2001 | J Bone Miner Res2001，16，5： | 1 |
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