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3198篇 您的检索式:作者名="Nicks"
    题名 作者 年代 出处 被引量
1独立董事背景与公司经营绩效显示文摘本文从独立董事背景的角度检验其对公司经营业绩的影响。研究发现,独立董事的教育背景对公司业绩并没有正面的影响,同时发现有政府背景和银行背景的独立董事比例越高,公司经营业绩越好。研究的结果也支持限制个人担任过多独立董事的主张。本文的研究在丰富了公司治理文献的同时,对于正确理解独立董事对公司经营业绩的影响也提供了新的观点,并对我国公司治理的进一步改革提供了重要的经验证据。魏刚 肖泽忠 Nick Travlos 邹宏 2007经济研究2007,42,3:282
2铁同位素的MC-ICP-MS测定方法与地质标准物质的铁同位素组成显示文摘详细报道了在低分辨和高分辨模式下运用MC-ICP-MS进行Fe同位素比值高精度测试的方法,对Fe同位素测定过程中谱峰干扰、基质效应、浓度效应、仪器测试的长期重现性等问题进行了评估,并对两种运行模式的测试结果进行了对比。在95%的可信度范围内,所建方法的外部精度优于0.5ε/amu,达到国际同类实验室的先进水平,并且低分辨和高分辨两种模式下获得的Fe同位素测试结果是一致的。在此基础上对国家地质标准物质GBW 07105(玄武岩)和GBW 07111(花岗闪长岩)进行了Fe同位素测定。相对于Fe同位素国际标样IRMM-014,GBW 07105的Fe同位素成分为:ε57Fe=1.9±0.3(2σ),ε56Fe=1.3±0.2(2σ),ε57/56Fe=0.6±0.1(2σ);GBW 07111的Fe同位素成分为:ε57Fe=1.8±0.4(2σ),ε56Fe=1.2±0.2(2σ),ε57/56Fe=0.6±0.1(2σ)。朱祥坤 李志红 赵新苗 唐索寒 何学贤 Nick S.Belshaw 2008岩石矿物学杂志2008,27,4:67
3重型机动车实际排放特性与影响因素的实测研究显示文摘利用美国Sensors公司生产的SEMTECHD车载排放测试仪在上海随机选择了7辆重型柴油车开展实际道路的排放测试,该实验累积测试道路长度为186km,共取得29090个逐秒的有效工况点数据,其中城市主干道12979个,次干道12368个,快速干道3743个.给出了车辆在不同道路上的工况点分布,分析了速度、加速度对燃油消耗、尾气排放的影响.测试结果表明,在选定的城市道路上,车流的平均怠速工况比为17%,加速工况比23.6%,等速工况比为31.0%,减速工况比为28.5%.被测车辆的CO、THC、NOx平均排放因子分别为(4.41±2.46)g·km-1、(1.77±1.17)g·km-1和(6.96±1.93)g·km-1,车辆排放状况因车速、加速度等因素而不同.测试结果基本反映了目前上海道路的交通状况和柴油卡车的排放现状,同时也说明过低的车速和频繁加减速是加重机动车污染的重要原因.陈长虹 景启国 王海鲲 潘汉生 李莉 黄成 赵静 戴懿 黄海英 Matt Barth Nick Nikkila 2005环境科学学报2005,25,7:57
4Shear strength criteria for rock,rock joints,rockfill and rock masses:Problems and some solutions显示文摘Although many intact rock types can be very strong,a critical confining pressure can eventually be reached in triaxial testing,such that the Mohr shear strength envelope becomes horizontal.This critical state has recently been better defined,and correct curvature or correct deviation from linear Mohr-Coulomb(MC) has finally been found.Standard shear testing procedures for rock joints,using multiple testing of the same sample,in case of insufficient samples,can be shown to exaggerate apparent cohesion.Even rough joints do not have any cohesion,but instead have very high friction angles at low stress,due to strong dilation.Rock masses,implying problems of large-scale interaction with engineering structures,may have both cohesive and frictional strength components.However,it is not correct to add these,following linear M-C or nonlinear Hoek-Brown(H-B) standard routines.Cohesion is broken at small strain,while friction is mobilized at larger strain and remains to the end of the shear deformation.The criterion 'c then σn tan φ' should replace 'c plus σn tan φ' for improved fit to reality.Transformation of principal stresses to a shear plane seems to ignore mobilized dilation,and caused great experimental difficulties until understood.There seems to be plenty of room for continued research,so that errors of judgement of the last 50 years can be corrected.Nick Barton 2013Journal of Rock Mechanics and Geotechnical Engineering2013,5,4:41
5胃癌预防亚太地区共识指南显示文摘背景与目的:胃癌是亚太地区的主要健康负担之一,但对其预防策略尚缺乏共识。本共识会议旨在评价预防胃癌的策略。方法:多学科专家组应用德尔菲(Delphi)法制订共识条文,提呈相关数据,对证据等级、推荐强度以及共识水平予以分级。结果:幽门螺杆菌(H.pylori)感染是非贲门胃腺癌必要但非充分的致病因子。盐的高摄入与胃癌强烈相关。新鲜果蔬对胃癌具有预防作用,但维生素和其他饮食补充并不能预防胃癌。H.pylori感染中的宿主-细菌相互作用导致不同类型的胃炎和胃酸分泌,从而决定疾病结局。胃癌阳性家族史是一个重要的危险因素。低血清胃蛋白酶原反映胃萎缩程度,可作为检出胃癌高危人群的标志物。H.pylori筛查和治疗被推荐作为减少高危人群胃癌危险性的一种策略,该策略在萎缩性胃炎发生前实施最为有效,但并不排除对胃癌高危人群的内镜监测。对胃癌低危人群不推荐行H.pylori筛查。H.pylori感染的一线治疗应遵循国家治疗指南。结论:高危人群中H.pylori筛查和根除策略可能会减少胃癌的发生率,本共识根据现有证据予以推荐。Kwong Ming Fock Nick Talley Paul Moayyedi Richard Hunt Takeshi Azuma Kentaro Sugano Shu Dong Xiao Shiu Kum Lam Khean Lee Goh Tsutomu Chiba Naomi Uemura Jae G Kim Nayoung Kim Tiing Leong Ang Varocha Mahachai Hazel Mitchell Abdul Aziz Rani Jyh Ming Liou Ratha-korn Vilaichone Jose Sollanor 钱本余 2008胃肠病学2008,13,4:37
6Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer显示文摘Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer.Jonathan Landy Emma Ronde Nick English Sue K Clark Ailsa L Hart Stella C Knight Paul J Ciclitira Hafid Omar Al-Hassi 2016World Journal of Gastroenterology2016,22,11:39
7轻型柴油车排放特性与机动车比功率分布的实例研究显示文摘引入机动车比功率概念研究了驾驶条件(Diving Condition)对机动车排放的影响及二者间的关系.利用美国Sensors公司生产的SEMTECHD车载排放测试仪在上海选取2辆轻型柴油客货两用车开展了实际道路排放测试.测试道路包括城市快速道、主干道和次干道,2辆轻型车测试的道路全长分别为31.8和39.7 km.通过计算逐秒的比功率值,研究了实际行驶中机动车比功率(VSP)与机动车油耗、空燃比和污染物排放的关系.回归分析结果表明,比功率比加速度能够更好地反映与NOx排放之间的关系,不同道路上机动车的CO、TC、NOx排放速率和油耗的比功率区间(VSP bin)分布具有较好的一致性.实测研究中VSP bin分布于-20~20 kW·t-1的范围内,其中超过50%的数据分布在-3~1 kW·t-1之间.高排放集中在分布频率较低的高VSP区间.应用污染物排放与VSP分布的关系式和VSP bins的频率分布可以估算机动车污染物排放总量.排放速率计算式具有一定的不确定性,还有待将来进一步修正.潘汉生 陈长虹 景启国 黄成 黄海英 王海鲲 李莉 赵静 戴懿 蔺宏轶 王少俊 Matt Barth Nick Nikkila 2005环境科学学报2005,25,10:30
8新疆西天山吐拉苏火山盆地金矿的构造控矿规律显示文摘新疆西天山吐拉苏火山盆地金矿在不同尺度上受不同级别的构造控制。在大地构造尺度上 ,Ⅰ级控矿构造为与博罗科努古生代岛弧带平行的NWW向基底断裂带 ,该断裂带控制与石炭纪火山岩有关的金矿带的展布。在区域尺度上 ,Ⅱ级控矿构造为NW向走滑断裂和NE向张性断裂 ,控制金矿床的分布。在矿床尺度上 ,Ⅲ级控矿构造为陡倾的近SN向张性断裂和与破火山口有关的环状断裂 ,控制金矿体的定位和产状。张桂林 梁金城 Nick Hayward 漆树基 2002地质与勘探2002,38,5:29
9History of the infantile hepatic hemangioma:From imaging to generating a differential diagnosis显示文摘We aim to provide an up-to-date summary of infantile hepatic hemangioma(IHH) and its misnomers and to dialectically present the differential diagnosis of these rare entities of the liver.Eligible peer-reviewed articles on hepatic infantile hemangiomas,published between 2000 and 2015,were reviewed for this study.IHH is the most common hepatic vascular tumor in children.Once a liver mass is identified in an infant,the differential diagnosis ranges from vascular malformations to benign and malignant tumors including mesenchymal hamartoma,hepatoblastoma,metastatic neuroblastoma,so careful physical examination,imaging studies,and,if indicated,tumor markers and biopsy,are of pivotal importance to ascertain the correct diagnosis.Despite the benign nature of IHHs,some of these lesions may demand medical and/or surgical intervention,especially for multiple and diffuse IHH.Complications can include hepatomegaly,hypothyroidism and cardiac failure.Therefore,a close follow-up is required until complete involution of the lesions.We propose an algorithm to guide the physicians towards the proper management of hepatic lesions.Maria Gnarra Gerald Behr Alison Kitajewski June K Wu Sudha A Anupindi Carrie J Shawber Nick Zavras Dimitrios Schizas Chris Salakos Konstantinos P Economopoulos 2016World Journal of Clinical Pediatrics2016,5,3:27
10Mg_2Si及Si粒子在Al-Mg-Si合金晶间腐蚀中协同作用机理的多电极偶合研究显示文摘通过测定Al-Mg-Si合金晶界各组成相的极化曲线及不同Mg/Si比Al-Mg-Si合金晶界组成相(AlMg_2Si及Al-Mg_2Si-Si)间的动态电化学偶合行为,研究了不同Mg/Si比Al-Mg-Si合金的晶间腐蚀机理。研究表明,晶界Si电位比其边缘Al基体正,在整个腐蚀过程中作为阴极导致其边缘Al基体的阳极溶解。晶界Mg_2Si电位比其边缘Al基体负,在腐蚀初期将作为阳极而发生阳极溶解;由于Mg_2Si中活性较高元素Mg的优先溶解,不活泼元素Si富集,致使Mg_2Si电位正移,甚至与其边缘Al基体发生极性转换,导致其边缘Al基体的阳极溶解。Mg/Si>1.73的Al-Mg-Si合金晶界只存在不连续分布的含Mg、Si的析出相,不能在晶界形成连续腐蚀通道,合金不表现出晶间腐蚀敏感性。Mg/Si<1.73的Al-Mg-Si合金晶界同时析出含Mg、Si析出相和Si粒子;腐蚀首先萌生于Mg_2Si相;而后,Si粒子一方面导致其边缘无沉淀带严重的阳极溶解,另一方面通过加速Mg_2Si和晶界无沉淀带的极性转换,协同促进了Mg_2Si边缘无沉淀带的阳极溶解,即腐蚀沿晶界Si粒子及Mg_2Si粒子边缘的无沉淀带发展。Si粒子促进了腐蚀的发展,导致合金表现出严重的晶间腐蚀敏感性。李朝兴 李劲风 BIRBILIS Nick 贾志强 郑子樵 2010中国腐蚀与防护学报2010,30,2:25
11The boring billion? - Lid tectonics, continental growth and environmental change associated with the Columbia supercontinent显示文摘The evolution of Earth’s biosphere,atmosphere and hydrosphere is tied to the formation of continental crust and its subsequent movements on tectonic plates.The supercontinent cycle posits that the continental crust is periodically amalgamated into a single landmass,subsequently breaking up and dispersing into various continental fragments.Columbia is possibly the frst true supercontinent,it amalgamated during the 2.0e1.7 Ga period,and collisional orogenesis resulting from its formation peaked at 1.95-1.85 Ga.Geological and palaeomagnetic evidence indicate that Columbia remained as a quasi-integral continental lid until at least 1.3 Ga.Numerous break-up attempts are evidenced by dyke swarms with a large temporal and spatial range;however,palaeomagnetic and geologic evidence suggest these attempts remained unsuccessful.Rather than dispersing into continental fragments,the Columbia supercontinent underwent only minor modifcations to form the next supercontinent(Rodinia)at 1.1-0.9 Ga;these included the transformation of external accretionary belts into the internal Grenville and equivalent collisional belts.Although Columbia provides evidence for a form of‘lid tectonics’,modern style plate tectonics occurred on its periphery in the form of accretionary orogens.The detrital zircon and preserved geological record are compatible with an increase in the volume of continental crust during Columbia’s lifespan;this is a consequence of the continuous accretionary processes along its margins.The quiescence in plate tectonic movements during Columbia’s lifespan is correlative with a long period of stability in Earth’s atmospheric and oceanic chemistry.Increased variability starting at 1.3 Ga in the environmental record coincides with the transformation of Columbia to Rodinia;thus,the link between plate tectonics and environmental change is strengthened with this interpretation of supercontinent history.Nick M.W.Roberts 2013Geoscience Frontiers2013,4,6:26
12日光温室封闭式栽培系统的设计与试验显示文摘土壤连作灾害、生产资源严重浪费和环境污染已成为日光温室生产中制约其发展的瓶颈问题,为了解决这些问题,实现节水、节肥、保护环境的目的并提高温室生产的管理水平和自动化水平,该文设计了一种日光温室封闭式栽培系统。与传统栽培管理方式不同,该系统使用基质栽培代替土栽方式,采用基质袋装或塑料薄膜完全包裹的模式,实现了与外界环境的有效隔离;使用水肥一体化营养液滴灌代替水肥分离灌溉方式,回收多余营养液并循环利用;采用无线传感器网络模式,实现了温室环境信息的自动采集和发送。试验结果表明,采用封闭式栽培比传统土栽方式番茄产量提高了11.7%,水、肥用量均节省了2%(基质不同,节省水、肥量不同),同种基质情况下,采用封闭式栽培方式,由于营养液实现了循环利用,水、肥节省率可以达到17.2%。袁洪波 王海华 庞树杰 李莉 Nick Sigrimis 2013农业工程学报2013,29,21:25
13伊犁京希—伊尔曼德金矿床的热液蚀变及成矿流体演化特征显示文摘京希—伊尔曼德金矿床的热液蚀变在空间上有明显的分带性,中心蚀变带以强烈的硅化为主,典型的蚀变矿物组合为石英或玉髓和地开石,中间带为高级泥化带,以地开石-高岭石-石英或玉髓为特征;外带为以蒙脱石-高岭石-伊利石-其他粘土矿物等矿物组合为主的泥化带,蚀变强度和矿物组合的分带性是温度、压力和化学梯度的反映,是流体在不断的水或流体—岩石反应和成分交换的产物。该矿床成矿流体演化过程为:早期酸性(pH=2~3)含矿流体在沿断裂上升过程中,受围岩灰岩中的流体(pH为中性)缓冲,在其进入高渗透性的碎屑岩层时,流速和水—岩石或流体—岩石反应大大加快,并在与大气降水的混合作用下,pH值逐步升高(3~5),产生了流体的温度及成分梯度,在温度和压力迅速下降的条件下,金及蚀变矿物沉淀、结晶生长,形成了蚀变空间分带,中心带保存完好的多孔状石英和地开石等高级泥化矿物组合说明该矿床是高硫化热液体系作用下的产物。肖龙 王方正 付民禄 BEGG Graham HAYWARD Nick 2001地质学报2001,75,4:26
14Recent advances in biodegradation controls over Mg alloys for bone fracture management: A review显示文摘Magnesium(Mg) alloys possess comparable physical and mechanical properties to bone, making them an outstanding candidate of implant materials for bone fracture treatment. In addition to the excellent biocompatibility, and bioactivity, the engagement of Mg alloys is key for a number of biological functionalities in the human body. The unique biodegradation nature of Mg alloy implants implies that it may not require a secondary removal procedure when the expected supporting tasks accomplish, as they may simply and safely 'disappear' over time. Nonetheless, the demonstrated drawback of potentially rapid degradation, is an issue that must be addressed appropriately for Mg implants and is consequently given unique attention in this review article. Herein, the critical criteria and the state-of-the-art strategies for controlling the degradation process of Mg alloys are reported. Furthermore, future developments of biodegradable Mg and its alloys systems with satisfactory specifications for clinical trials and deployment,are discussed. This review aims to provide information to materials scientists and clinical practitioners in the context of developing practical biodegradable Mg alloys.Ming-Shi Song Rong-Chang Zeng Yun-Fei Ding Rachel W.Li Mark Easton Ivan Cole Nick Birbilis Xiao-Bo Chen 2019Journal of Materials Science & Technology2019,35,4:26
15FAIR Principles:Interpretations and Implementation Considerations显示文摘The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in 2016.By intention,the 15 FAIR guiding principles do not dictate specific technological implementations,but provide guidance for improving Findability,Accessibility,Interoperability and Reusability of digital resources.This has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder communities can implement their own FAIR solutions.However,it has also resulted in inconsistent interpretations that carry the risk of leading to incompatible implementations.Thus,while the FAIR principles are formulated on a high level and may be interpreted and implemented in different ways,for true interoperability we need to support convergence in implementation choices that are widely accessible and(re)-usable.We introduce the concept of FAIR implementation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR implementations.Any self-identified stakeholder community may either choose to reuse solutions from existing implementations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other communities in the future.Here,we provide interpretations and implementation considerations(choices and challenges)for each FAIR principle.Annika Jacobsen Ricardo de Miranda Azevedo Nick Juty Dominique Batista Simon Coles Ronald Cornet Melanie Courtot Merce Crosas Michel Dumontier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft Melanie Imming Keith G.Jeffery Rajaram Kaliyaperumal Martijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara Magagna PeterMcQuilton Natalie Meyers Annalisa Montesanti Mirjam van Reisen Philippe Rocca-Serra Robert Pergl Susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn Mark Thompson Andra Waagmeester Tobias Weigel Mark D.Wilkinson Egon L.Willighagen Peter Wittenburg Marco Roos Barend Mons Erik Schultes 2020Data Intelligence2020,2,1:26
16社会硅谷:社会创新的发生与发展显示文摘社会创新是为满足社会需求而进行的创造性行动和服务。近年来,随着人口老龄化、环境污染、酗酒等社会问题的日益严重,社会创新已迫在眉睫。尽管社会创新时有发生,但较之于商业和科技创新,人们对这方面的研究却较少。本文紧紧围绕社会创新的概念、发展简史、动力和过程等展开讨论,并把组合各种资源和能量以推动社会创新的机构喻为“社会硅谷”。杰夫.摩根 Nick Wilkie Simon Tucker Rushanara Ali Francis Davis 张晓扬 2006经济社会体制比较2006,,5:24
17转录因子RORγt对妊娠期哮喘模型小鼠Th17/Treg平衡的调节作用显示文摘目的观察妊娠期哮喘模型小鼠Th17细胞相关细胞因子和维甲酸相关孤儿受体γt(RORγt)的表达变化,探讨地塞米松(DXM)对小鼠气道炎症和Th17细胞分泌功能的影响。方法 30只雌性BALB/c小鼠随机分为健康妊娠(HP)组、妊娠期哮喘(AP)组和地塞米松(DXM)组,每组10只。AP组和DXM组于实验当天(0d)和7、14d时分别给予OVA/Al(OH)3混悬液腹腔注射致敏,HP组仅给予单纯等量生理盐水(NS)。3组小鼠合笼交配至妊娠成功。于21d起,连续7d对AP组和DXM组给予50g/L OVA雾化激发(1次/d,40min/次);DXM组于雾化吸入OVA前30min给予1mg/kgDXM腹腔注射;HP组仅给予单纯等量NS进行雾化激发。各组小鼠于末次激发24h后进行气道反应性检测,结果以相应浓度乙酰胆碱(Mch)激发下增强的呼吸间歇(Penh)值与基线值的百分比[Penh值(%)]来表示;分析支气管肺泡灌洗液(BALF)中白细胞总数及分类计数;取肺组织行病理学观察;采用流式细胞仪检测外周血Th17和Treg细胞的比例并计算Th17/Treg比值;ELISA法测定外周血IL-17、IL-23、IFN-γ和RORγt含量,RT-PCR法检测前述因子在肺组织中的表达,Western blotting检测肺组织中RORγt的表达。结果雌性BALB/c小鼠以OVA致敏后气道反应性增加,BALF中白细胞总数及嗜酸性粒细胞(Eos)、淋巴细胞(Lym)和中性粒细胞(Neu)比例增加,肺组织病理学改变符合哮喘的特征。外周血标本中,AP组Th17细胞显著升高,Treg细胞显著降低(P<0.05),Th17/Treg比值上升。DXM组Th17和Treg细胞变化趋势与AP组相同,Th17/Treg比值高于HP组,但低于AP组(P<0.05)。分别在肺组织和外周血标本中检测蛋白和mRNA表达水平,结果显示,AP组IL-17、IL-23及RORγt含量均高于HP组及DXM组(P<0.05),IFN-γ含量低于HP组及DXM组(P<0.05)。AP组肺组织RORγt蛋白的表达(61.27%±3.11%)明显高于DXM组(37.51%±1.93%,P<0.01)和HP组(22.39%±0.86%,P<0.01),后两者比较差异亦有统计学意义(P<0.01)。相关分析表明,AP组肺组织RORγt蛋白表达量与Eos、Lym和Neu细胞绝对值呈显著正相关(r=0.879、0.759、0.802,P<0.01),与外周血IL-17含量、肺组织IL-17mRNA表达水平亦呈正相关(r=0.696、0.863,P<0.01)。结论 Th17细胞分泌功能及RORγt表达上调参与了妊娠期哮喘的发生发展。DXM干预在改善哮喘症状的同时可降低RORγt表达,使Th17分化和增殖功能受抑。马佳佳 Nick Lu 陈必良 2012解放军医学杂志2012,37,6:20
18上海市城区典型道路行驶特征研究显示文摘对上海市城区快速干道、主干道和次于道等3种典型道路上的机动车行驶特征和交通状况进行试验和调查,得出了上海市城区各类道路上机动车行驶特征参数和交通密度。结果显示,上海市城区各类道路综合行驶特征为平均速度低,加减速频繁。其中又以主干道交通状况最差。文中的数据和结论不仅可以用于上海城市交通规划,而且对控制道路两旁机动车污染具有重要意义。王海鲲 陈长虹 黄成 戴懿 赵静 Jim Lents Matt Barth Nick Nikkilia 2005交通环保2005,26,3:16
19能效建筑规划设计方法显示文摘介绍一种应用灵活、使用方便的能效建筑规划设计方法;该方法可以对单个建筑及群体建筑进行综合能效规划设计, 为建筑师开展建筑可持续建筑发展提供了有力工具。姚润明 Koen Steemers Nick Baker 李百战 2004建筑学报2004,,8:14
20腹腔镜规则性右半肝切除12例临床分析显示文摘目的探讨腹腔镜规则性右半肝切除术的可行性。方法12例腹腔镜右半肝切除术病例中,10例被怀疑为恶性病变。手术按照:1、肝门解剖,2、腔静脉解剖,3、肝实质切除的步骤进行。结果5例在腹腔镜下完成手术,5例腹腔镜辅助下完成手术,2例中转开腹肝切除。4例需要输血。全组有1例出现胆漏,1例切口裂开,无死亡病例。全组平均住院8.3 d,完全在腹腔镜下完成手术的病例平均住院日为4.1 d。被诊断为肝癌的9例,随访中2例死亡,1例为肝癌肝内转移.1例为结肠癌转移灶切除术后的广泛转移。另7例结肠癌肝转移患者随访6-24个月,至今存活。结论腹腔镜下右半肝切除术在选择性病例基础上施行是可行和安全的。吴志明 Les Nathanson Nick O’Rourke 2006中华普通外科杂志2006,21,1:13
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