|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Heme oxygenase-1 overexpression increases liver injury after bile duct ligation in rats显示文摘AIM: To investigate the effects of heme oxygenase-1 (HO-1) against oxidant-induced injury caused by bile duct ligation (BDL). METHODS: Either cobalt protoporphyrin (CoPP), a HO-1 inducer, or saline were injected intraperitoneally in male SD-rats. Three days later, BDL or sham-operations were performed. Rats were sacrificed 3 wk after BDL and livers were harvested for histology. Fibrosis was evaluated by sirius red staining and image analysis. Alpha-smooth muscular actin, which indicates activation of stellate cells, was detected by immunohistochemical staining, and cytokine and collagen-Ⅰα (Col-Ⅰα) mRNA expression was detected using RNase protection assays. RESULTS: Serum alanine transaminase increased 8-fold above normal levels one day after BDL. Surprisingly, enzyme release was not reduced in rats receiving CoPP. Liver fibrosis was evaluated 3 wk after BDL and the sirius red-positive area was found to be increased to about 7.8%. However, in CoPP pretreated rats sirius red- positive areas were increased to about 11.7% after BDL. Collagen-Ⅰα and TGF-β mRNA increased significantly by BDL. Again, this effect was increased by HO-1 overexpression.CONCLUSION: Hepatic fibrosis due to BDL is not reduced by the HO-1 inducer CoPP. In contrast, HO-1 overexpression increases liver injury in rats under conditions of experimental chronic cholestasis. | Matthias Froh Lars Conzelmann Peter Walbrun Susanne Netter Reiner Wiest Michael D Wheeler Mark Lehnert Takehiko Uesugi Jurgen Scholmerich Ronald G Thurman | 2007 | World Journal of Gastroenterology2007，13，25： | 4 |
| 2 | Endogeneity and the Dynamics of Internal Corporate Governance显示文摘 | Wintoki M B Linck J S Netter J M | 2012 | Journal of Fi-nancial Economics2012，105，3： | 1 |
| 3 | Endogeneity and the dynamics of internal corporate governance显示文摘 | Wintoki M B Linck J S Netter J M | 2012 | Journal of Fi- nancial Economics2012，105，： | 1 |
| 4 | A defined serum-free medium useful for monitoring antimelanoma responses induced by dendritic cell immunotherapy显示文摘 | Bouwer A L Netter P Kemp R A | 2010 | Journal of Immunological Methods2010，352，12： | 1 |
| 5 | Endogeneity and the dynamics of internal corporate governance 显示文摘 | Wintoki M B Linck J S Netter J M | 2012 | Jour- nal of Financial Economics2012，105，3： | 1 |
| 6 | Anti-hepatitis Bactivity of isoquinoline alkaloids of plant origin 显示文摘 | Aljofan M Netter HJ Aljarbou AN | 2014 | Ar- chives of Virology2014，159，5： | 1 |
| 7 | The Market For Corporate Control: The Empirical Evidence Since 1980 显示文摘 | G Jarrell J Brickley J Netter | 1988 | Journal of Economic Perspectives1988，，： | 1 |
| 8 | Influence of the projectiles' mate- rial in a coilgun 显示文摘 | HINAJE M NETTER D | 2006 | European Journal of Physics2006，27，1： | 1 |
| 9 | Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site显示文摘 | JAUCH R J KEL S NETTER C | 2005 | Structure2005，13，10： | 1 |
| 10 | Share Issue Privatizations as Financial Means to Political and Economic Ends 显示文摘 | Jones S L W L Megginson R C Nash J M Netter | 1999 | Joumal of Financial Economics1999，53，2： | 1 |
| 11 | From state to market:a survey of empirical studies on privatization显示文摘 | Megginson W Netter J | | 0，，39： | 1 |
| 12 | Fatigue Life Prediction of a Railway Bogie under Dynamic Loads through Simulation显示文摘 | Stefan Dietz Helmuth Netter Dell Sachau | 1998 | Vehicle Systems Dynamics Supplement1998，29，： | 1 |
| 13 | What do returns to acquiring firms tell us?Evidence from firms that make many acquisitions 显示文摘 | Fuller Netter Stegemoller | 2002 | Journal of Finance2002，57，： | 1 |
| 14 | Private benefits of control:an international comparison显示文摘 | Jarrel Brickle yand Netter | | 0，，： | 1 |
| 15 | Mechanisms of changes in lymphocyte numbers after psychological stress显示文摘 | Henning J Netter P Voigt k etal | 2000 | Z Rheumatol2000，59，2： | 1 |
| 16 | Determinants of Contractual Relations between Shareholders and Bondholders: Investment Opportunities and Restrictive Covenants 显示文摘 | Nash Netter Poulsen | 2003 | Journal of Corporate Finance2003，9，2： | 1 |
| 17 | From State To Market: A Survey of Empirical Studies on Privatization 显示文摘 | Megginson W Netter J | 2001 | Journal of Economic Literature2001，39，2： | 1 |
| 18 | Bone mineralization defects and vitamin D deficiency:histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients显示文摘 | Priemel M von Domarus C Klatte TO Kessler S Schlie J Meier S Proksch N Pastor F Netter C Streichert T Püschel K Amling M | | 0，，： | 1 |
| 19 | Immunogenicity of recombinant HBsAg/HCV particles in mice pre-immunised with hepatitis B virus-specific vaccine显示文摘 | Netter HJ Woo WP Tindle R | 2003 | Vaccine2003，21，2122： | 1 |
| 20 | Endogeneity and the dynamics of internal corporatc governance显示文摘 | Wintoki M B Linck J S Netter J M | 2010 | CELS 2009 4th Annual Conference on Emperical Conference on Empirical Legal Studics Paper2010，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员