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| 1 | Correlation of central corneal thickness measurements using Topcon TRK‐1P, Zeiss Visante AS‐OCT and DGH Pachmate 55 handheld ultrasonic pachymeter显示文摘 | Matthew Wells Nerida Wu Jim Kokkinakis Gerard Sutton | 2013 | Clin Exp Optom2013，，4： | 1 |
| 2 | Evaluation of synergistic activity of bovine lactoferricin with antibiotics in corneal infection显示文摘 | ZAW O T NERIDA C LINDA G | 2010 | Antimicrob Chemother2010，65，6： | 1 |
| 3 | Isoflavonoid photoprotection in mouse and human skin is dependent on metallothionein显示文摘 | Sitarina W Munif A Nerida L G | 2006 | Journal of Investigative Dermatology2006，126，1： | 1 |
| 4 | Factors influencing bacterial a- dhesion to contact lenses 显示文摘 | Debarun D Nerida C Mark W | 2012 | Molecular Vision2012，18，3： | 1 |
| 5 | Working memory training with tDCS improves behavioral and neurophysiological symptoms in pilot group with post-traumatic stress disorder (PTSD) and with poor working memory显示文摘 | Nerida Saunders Russell Downham Bulent Turman Juri Kropotov Richard Clark Rustam Yumash Arielle Szatmary | 2015 | Neurocase2015，，3： | 1 |
| 6 | Antimicrobial,antiviral,and cytotoxic activity of Newland lichens 显示文摘 | Nigel B Michael H Nerida J | 1990 | Lichenologist1990，31，6： | 1 |
| 7 | Corneal erosions in contact lens wear显示文摘 | Maria Markoulli Eric Papas Nerida Cole Brien Holden | 2012 | Contact Lens and Anterior Eye2012，35，1： | 1 |
| 8 | Understanding communication networks in the emergency Department 显示文摘 | Nerida Creswick Johanna I Westbrook Jeffrey Braithwaite | 2009 | BMC Health Services Research2009，9，： | 1 |
| 9 | Animicrobial crobial,antiviral and cytotoxic activityof New Zealand lichens显示文摘 | PERRY NIGEL B BENN MICHAEL H BRENNAN NERIDA J | 1999 | Lichenologist1999，31，6： | 1 |
| 10 | A dahlia flower extract has antidiabetic properties by improving insulin function in the brain显示文摘Butein,a rare chalcone found in the toxic plant Toxicodendron vernicifluum,has been shown to regulate glucose homeostasis via inhibition of the nuclear factor kappa-B kinase subunit beta(IKKβ)/nuclear factor kappa B(NF-κB)pathway in the brain.Here,we investigated whether the nonpoisonous plant Dahlia pinnata could be a source of butein as a potential treatment for type 2 diabetes(T2D).In mice fed a high-fat diet(HFD)to induce glucose intolerance,an oral D.pinnata petal extract improved glucose tolerance at doses of 3.3 mg/kg body weight and 10 mg/kg body weight.Surprisingly,this effect was not mediated by butein alone but by butein combined with the closely related flavonoids,sulfuretin and/or isoliquiritigenin.Mechanistically,the extract improved systemic insulin tolerance.Inhibition of phosphatidylinositol 3-kinase to block insulin signaling in the brain abrogated the glucoregulatory effect of the orally administered extract.The extract reinstated central insulin signaling and normalized astrogliosis in the hypothalamus of HFD-fed mice.Using NF-κB reporter zebrafish to determine IKKβ/NF-κB activity,a potent anti-inflammatory action of the extract was found.A randomized controlled crossover clinical trial on participants with predia-betes or T2D confirmed the safety and efficacy of the extract in humans.In conclusion,we identified an extract from the flower petals of D.pinnata as a novel treatment option for T2D,potentially targeting the central regulation of glucose homeostasis as a root cause of the disease. | Dominik Pretz Philip M.Heyward Jeremy Krebs Joel Gruchot Charles Barter Pat Silcock Nerida Downes Mohammed Zubair Rizwan Alisa Boucsein Julia Bender Elaine J.Burgess Geke Aline Boer Pramuk Keerthisinghe Nigel B.Perry Alexander Tups | 2023 | Life Metabolism2023，2，4： | 0 |
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