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| 1 | 腹腔镜外科学基础认证项目简介及其对中国外科医师的意义显示文摘腹腔镜外科学基础(FLS)项目是普通外科中第1个经过验证的操作和认知考核项目.FLS由美国胃肠内镜外科医师协会(SAGES)开发并得到美国外科医学委员会(ABS)的支持.ABS要求所有拟参加普通外科医师执业资格考试前必须通过FLS考试.在美国,普通外科医师执业资格考试是取得执业资格的第一步.本文回顾了FLS项目在美国取得的成功经验,并就该项目在中国推广标准化腹腔镜外科技术中的应用和获益进行了介绍. | Linda P Zhang Samuel R G Finlayson Allan Okrainec Steven D Schwaitzberg | 2014 | 中华消化外科杂志2014，13，9： | 5 |
| 2 | Hepatitis E virus in patients with acute severe liver injury显示文摘AIM: To examine the incidence of hepatitis E(HepE) in individuals with acute liver injury severe enough to warrant treatment at a transplant unit.METHODS: Hepatitis E virus(HEV) is an emerging pathogen in developed countries causing severe illness, particularly in immunocompromised patients or those with underlying chronic liver disease. HepE infection isoften under diagnosed, as clinicians can be reluctant to test patients who have not travelled to regions traditionally considered hyperendemic for HepE. There are few data regarding the significance of HEV in patients with very severe acute liver injury in developed countries. Eighty patients with acute severe liver injury attending the Scottish Liver Transplant unit were tested for HEV and anti-HEV IgG and IgM. Severe acute liver injury was defined as a sudden deterioration in liver function confirmed by abnormal liver function tests and coagulopathy or presence of hepatic encephalopathy. Eighty percent of these patients were diagnosed with paracetomol overdose. No patients had a history of chronic or decompensated chronic liver disease at time of sampling. IgG positive samples were quantified against the World Health Organization anti-HEV IgG standard. Samples were screened for HEV viral RNA by quantitative reverse transcription polymerase chain reaction.RESULTS: Four cases of hepatitis E were identified. Three of the four cases were only diagnosed on retrospective testing and were initially erroneously ascribed to drug-induced liver injury and decompensated chronic liver disease, with the cause of the decompensation uncertain. One case was caused by HEV genotype 1 in a traveller returning from Asia, the other three were autochthonous and diagnosed on retrospective testing. In two of these cases(where RNA was detected) HEV was found to be genotype 3, the most prevalent genotype in developed countries. Three patients survived, two of whom had been misdiagnosed as having drug induced liver injury. The fourth patient died from sepsis and liver failure precipitated as a result of hepatitis E infection and previously undiagnosed cirrhosis. Histopathology data to date is limited to mainly that seen for endemic HepE. All patients, with the exception of patient 1, demonstrated characteristics of HepE infection, as seen in previously described locally acquired cases.CONCLUSION: In patients with acute severe liver injury, HEV testing should be part of the initial diagnostic investigation algorithm irrespective of suspected initial diagnosis, age or travel history. | Claire Louise Crossan Kenneth J Simpson Darren G Craig Christopher Bellamy Janice Davidson Harry R Dalton Linda Scobie | 2014 | World Journal of Hepatology2014，6，6： | 4 |
| 3 | 伦理学与SARS:多伦多的教训显示文摘SARS的流行说明传染病在世界范围内流行是件多么容易的事,为了更好地应对下一次流行病,我们不仅要解决医学方面的问题,也同样需要解决伦理学方面的问题。 | Peter A Singer Solomon R Benatar Mark Bernstein Abdallah S Daar Bernard M Dickens Susan K MacRae Ross E G Upshur Linda Wright Randi Zlotnik Shaul 肖月 | 2004 | 英国医学杂志中文版2004，7，4： | 3 |
| 4 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 5 | Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study显示文摘BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor organs into what appears to be increasingly complex recipients;thus the identification of modifiable risk factors associated with poor outcomes is paramount.AIM To identify risk factors associated with delayed graft function(DGF).METHODS Consecutive adults undergoing DDKT between January 2016 and July 2017 were identified with a study population of 294 patients.The primary outcome was the occurrence of DGF.RESULTS The incidence of DGF was 27%.Under logistic regression,eight independent risk factors for DGF were identified including recipient body mass index≥30 kg/m^(2),baseline mean arterial pressure<110 mmHg,intraoperative phenylephrine administration,cold storage time≥16 h,donation after cardiac death,donor history of coronary artery disease,donor terminal creatinine≥1.9 mg/dL,and a hypothermic machine perfusion(HMP)pump resistance≥0.23 mmHg/mL/min.CONCLUSION We delineate the association between DGF and recipient characteristics of preinduction mean arterial pressure below 110 mmHg,metabolic syndrome,donorspecific risk factors,HMP pump parameters,and intraoperative use of phenylephrine. | Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu | 2021 | World Journal of Transplantation2021，11，4： | 2 |
| 6 | Probiotics stimulate liver and plasma protein synthesis in piglets with dextran sulfate induced colitis and macronutrient restriction显示文摘 | Scott V H Keely G F Linda J W | 2008 | Journal of Nutrition2008，138，： | 1 |
| 7 | PIK3CA mutatios in hunman solid tumors显示文摘 | Ligresti G Militello L Linda S | 2009 | Cell Cycle2009，8，9： | 1 |
| 8 | Efficacy of 1- MCP ( 1 - methylcyclopropene ) and promalin for extending the post-harvest life of oriental lilies(lilium ' Monalisa ' and ' Stargazer ') 显示文摘 | FISUN G LINDA L MICHAEL S | 2002 | Scientia Horticulturae2002，93，： | 1 |
| 9 | maternal and child undemutrition: Consequcnces for adult health and human capital 显示文摘 | CESAR G V LINDA A CAROLINE F | 2008 | The lancet2008，371，9607： | 1 |
| 10 | Cryopreservation of embryos and ova显示文摘 | Shevach F Linda C G Emmet J L | 1988 | Fert Steril1988，49，5： | 1 |
| 11 | The Psychometric Properties of the Orthogonal Cultural Identification Scale in Asian Americans显示文摘 | Mona L J Tamara LW Carmen G Linda TG Roberto J V | 2002 | Journal of Multicultural Counseling and Development2002，，30： | 1 |
| 12 | Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects 显示文摘 | BERNADETT K LINDA G | 2009 | Cell Mol Biol Lett2009，14，2： | 1 |
| 13 | Calculation of Average, Uncertainty Range and Reliability of Regional Climate Changes {rom AOGCM Simulations Via the ' Reliability Ensemble Averaging (REA) ' Method 显示文摘 | FILIPPO G LINDA O M | 2002 | Journal of Climate2002，15，10： | 1 |
| 14 | SHAPIRO, computerand robot vision显示文摘 | HARALICK ROBERT M LINDA G | 1992 | Addison- Wesley1992，1，8： | 1 |
| 15 | Pacitaxel and platinum chemotherapy for MMMTs of the ovary 显示文摘 | Audrey G Ganul H | 2002 | Gynecol Oncol2002，85，： | 1 |
| 16 | Molecular analysis of the rfb O antigen gene cluster of Salmonella enterica serogroup O: 6, 14 and development of a sero-group-specific PCR assay显示文摘 | Collette F Rachel S Linda L G | 2003 | Applied and Environmental Microbiology2003，69，10： | 1 |
| 17 | Experimental verification of the use of metal filled via hole fences for crosstalk control of microstrip lines in LTCC packages显示文摘 | George E Yook J G Linda P B | 2001 | IEEE Transaction on Advanced Packing2001，24，1： | 1 |
| 18 | Role of laparoscopic treatment of endometriosis :in patients with failed in vitro fertilization cycles显示文摘 | Eva L Linda G Ruth L | 2005 | Fertil Steril2005，84，6： | 1 |
| 19 | Endometriosis 显示文摘 | Linda C G Lee C K | 2004 | Lancet2004，364，9447： | 1 |
| 20 | Strepto- myces competition and co-evolution in relation to plant disease suppression 显示文摘 | Linda L K Daniel C S Matthew G B | 2012 | Research in Microbiology2012，163，8： | 1 |
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