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| 1 | Vitamin D and autoimmune thyroid diseases显示文摘The role of vitamin D as an immune modulator has been emphasized in recent years,and low levels of the hormone were observed in several autoimmune diseases including multiple sclerosis and systemic lupus erythematosus.Vitamin D mediates its effect though binding to vitamin D receptor(VDR),and activation of VDR-responsive genes.While VDR gene polymorphism was found to associate with autoimmune thyroid diseases(AITDs),few studies examined levels of vitamin D in these patients and those that did yielded conflicting results.We therefore undertook to evaluate the levels of vitamin D in patients with AITDs compared to patients with non-AITDs and healthy controls.Serum vitamin D(25-OH)levels were measured in 50 patients with AITDs,42 patients with non-AITDs and 98 healthy subjects,utilizing the LIAISON chemiluminescence immunoassay(DiaSorin,Saluggia,Italy).VitaminD deficiency was designated at levels lower than 10 ng/ml.Antithyroid antibodies,thyroid functions and demographic parameters were evaluated in all patients.The prevalence of vitamin D deficiency was significantly higher in patients with AITDs compared with healthy individuals(72% versus 30.6%;P<0.001),as well as in patients with Hashimoto’s thyroiditis compared to patients with non-AITDs(79% versus 52%;P<0.05).Vitamin D deficiency also correlated to the presence of antithyroid antibodies(P=0.01)and abnormal thyroid function tests(P=0.059).Significantly low levels of vitamin D were documented in patients with AITDs that were related to the presence of anti thyroid antibodies and abnormal thyroid function tests,suggesting the involvement of vitamin D in the pathogenesis of AITDs and the advisability of supplementation. | Shaye Kivity Nancy Agmon-Levin Michael Zisappl Yinon Shapira Endre V Nagy Katalin Danko Zoltan Szekanecz Pnina Langevitz Yehuda Shoenfeld | 2011 | Cellular & Molecular Immunology2011，8，3： | 47 |
| 2 | Symptoms and Subtypes in Pediatric Functional Dyspepsia: Relation to Mucosal Inflammation and Psychological Functioning显示文摘 | Jennifer V Schurman Meenal Singh Vivekanand Singh Nancy Neilan Craig A Friesen | 2010 | Journal of Pediatric Gastroenterology and Nutrition2010，，3： | 2 |
| 3 | Vitamin D metabolism and innate immunity 显示文摘 | Lagishetty V Nancy QL Hewison M | 2011 | Mol Cell Endocrinol2011，347，12： | 1 |
| 4 | Suppression of rice methane emission by sulfate deposition in simulated acid rain 显示文摘 | Gauci V Nancy B Howell G | 2008 | Journal of Geophysical Research2008，113，07： | 1 |
| 5 | Correction of age-related polyuria by dDAVP:molecular analysis of aquaporins and urea transporters显示文摘 | Sophie Combet Nancy Geffroy Véronique Berthonaud | 2003 | Am J Physiol Renal Physiol2003，284，： | 1 |
| 6 | A comparison of soil organic carbon stocks between residential turf grass and native soil 显示文摘 | Richard V P Ian D Y Nancy E G | 2009 | Urban Ecosystem2009，12，： | 1 |
| 7 | Vitamin D metabolism and innateimmunity显示文摘 | Lagishetty V Nancy QL Hewison M | 2011 | Mol Cell Endocrinol2011，347，12： | 1 |
| 8 | Effects of o,p’-DDE,heptachlor,and 17β-estradiol on vitellogenin gene expression and the growth hormone/insulin-like growth factor-I axis in the tilapia,Oreochromis mossambicus显示文摘 | Lori K D Nancy V Larry G R | 2009 | Comparative Biochemistry and Physiology Part C2009，149，4： | 1 |
| 9 | Chemotherapy for progressive optic-hypothalamic gliomas in young child显示文摘 | Eva O Peter V Nancy D | 2001 | AJNR2001，22，： | 1 |
| 10 | Separation and purification of glucoamylase in aqueous two-phase systems by two-step extraction显示文摘 | NANCY M M BEATRIZ V K | 1998 | Journal of Chromatography B1998，7，11： | 1 |
| 11 | Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through β2 recepto-dependent, No synthase-independent and cyclooxygennase-independent pathway显示文摘 | Brown MD James V | 2000 | Circulation2000，102，： | 1 |
| 12 | Brentuximab vedotin for the treatment of CD30+ lymphomas显示文摘 | Kelley V Foyil Nancy L Bartlett | 2011 | Immunotherapy2011，，： | 1 |
| 13 | Introduction to the Special Issue on Word Sense Disambiguation:The State of the Art显示文摘 | Nancy Ide Jean Véronis | 1998 | Computational Linguistics1998，24，1： | 1 |
| 14 | American Associa- tion of Neuroscience Nurses Scope and Standards of Prac- tice for Neuroscience Advanced Practice Nurses显示文摘 | Chris S A Nancy V Rossi S R | 2010 | J Neu- rosci Nurs2010，42，3： | 1 |
| 15 | Vitainin D metabolism and innate immunity显示文摘 | Lagishetty V Nancy QL Hewison M | 2011 | Mol Cell Endocrinol2011，347，12： | 1 |
| 16 | Performances of human listeners and an automatic aural classifier in discrim- inating between sonar target echoes and clutter显示文摘 | NANCY A HINES P C YOUNG V W | 2011 | J Acoust Soc Am2011，130，3： | 1 |
| 17 | Chemical characterization and mosquito larvicidal activity of essential oil from leaves of Persea americana Mill (Lauraceae) against Culex quinquefasciatus (Say)显示文摘 | Carlos Granados-Echegoyen Rafael Pérez-Pacheco Nancy Alonso-Hernández Alfonso Vásquez-López Luicita Lagunez-Rivera Alejandra Rojas-Olivos | 2015 | Asian Pacific Journal of Tropical Disease2015，，6： | 1 |
| 18 | Evidence for the Early Oligocene formation of a proto-subtropical convergence from oxygen isotope records of New Zealand Paleogene brachiopods显示文摘 | Nancy Buening Sandra J Carlson Howard J Spero v | 1998 | Palaeogeography Palaeoclimatology Palaeoecology1998，13，： | 1 |
| 19 | Introduction to the special issue on word sense disambiguation:the state of the art显示文摘 | Nancy Ide Jean Véronis | 1998 | Computational Linguistics1998，24，1： | 1 |
| 20 | Vitainin D metabolism and innate immunity显示文摘 | Lagishetty V nancy QL Hewison M | 2011 | Mol Cell Endocrinol2011，347，12： | 1 |
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