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| 1 | Asymmetric dimethylarginine, a biomarker of cardiovascular complications in diabetes mellitus显示文摘Cardiovascular(CV) complications are an essential causal element of prospect in diabetes mellitus(DM), with carotid atherosclerosis being a common risk factor for prospective crisis of coronary artery diseases and/or cerebral infarction in DM subjects. From another point of view, asymmetric dimethylarginine(ADMA) has been established as an inhibitor of endogenous nitric oxide synthesis and the relationship between ADMA and arteriosclerosis has been reported. In our study with 87 type 2 DM(T2DM) patients, we have examined whether ADMA and other CV risk factors are the useful predictors of DMCV complications. After the measurement of the respective CV risk factors, we have followed the enrolled T2 DM patients for 5 years. We have finally analyzed 77 patients. DMCV complications developed in 15 cases newly within 5 years, and 4 cases recurred. The concentrations of ADMA in plasma were markedly more elevated in 19 DM patients with CV complications than in 58 DM patients without CV complications. Urinary albumin(U-Alb), mean intimal-medial thickness(IMT) and ankle brachial index(ABI) were also higher in patients with CV complications. Multiple regression analyses showed that U-Alb had an influence on the high level of ADMA(standardized β = 6.59, P = 0.00014) independently of age, systolic BP, fibrinogen, mean IMT, plaque score, and ABI. The review indicates what is presently known regarding plasma ADMA that might be a new and meaningful biomarker of CV complications in DM subjects. | Hiroyuki Konya Masayuki Miuchi Kahori Satani Satoshi Matsutani Yuzo Yano Taku Tsunoda Takashi Ikawa Toshihiro Matsuo Fumihiro Ochi Yoshiki Kusunoki Masaru Tokuda Tomoyuki Katsuno Tomoya Hamaguchi Jun-ichiro Miyagawa Mitsuyoshi Namba | 2015 | World Journal of Experimental Medicine2015，5，2： | 16 |
| 2 | A critical review on the chemical wear and wear suppression of diamond tools in diamond cutting of ferrous metals显示文摘Diamond tools play a critical role in ultra-precision machining due to their excellent physical and mechanical material properties,such as that cutting edge can be sharpened to nanoscale accuracy.However,abrasive chemical reactions between diamond and non-diamond-machinable metal elements,including Fe,Cr,Ti,Ni,etc,can cause excessive tool wear in diamond cutting of such metals and most of their alloys.This paper reviews the latest achievements in the chemical wear and wear suppression methods for diamond tools in cutting of ferrous metals.The focus will be on the wear mechanism of diamond tools,and the typical wear reduction methods for diamond cutting of ferrous metals,including ultrasonic vibration cutting,cryogenic cutting,surface nitridation and plasma assisted cutting,etc.Relevant commercially available devices are introduced as well.Furthermore,future research trends in diamond tool wear suppression are discussed and examined. | Guo Jiang Zhang Jianguo Pan Yanan Kang Renke Namba Yoshiharu Shore Paul Yue Xiaobin Wang Baorui Guo Dongming | 2020 | International Journal of Extreme Manufacturing2020，2，1： | 7 |
| 3 | Hepatocyte growth factor, a biomarker of macroangiopathy in diabetes mellitus显示文摘Atherosclerotic involvements are an essential causal element of prospect in diabetes mellitus(DM), with carotid atherosclerosis(CA) being a common risk-factor for prospective crisis of coronary artery diseases(CAD) and/or cerebral infarction(CI) in DM subjects. From another point of view, several reports have supplied augmenting proof that hepatocyte growth factor(HGF) has a physiopathological part in DM involvements. HGF has been a mesenchymal-derived polyphenic factor which modulates development, motion, and morphosis of diverse cells, and has been regarded as a humor intermediator of epithelial-mesenchymal interplays. The serum concentrations of HGF have been elevated in subjects with CAD and CI, especially during the acute phase of both disturbances. In our study with 89 type 2 DM patients, the association between serum concentrationsof HGF and risk-factors for macrovascular complicationsinclusive of CA were examined. The average of serumHGF levels in the subjects was more elevated than thereference interval. The serum HGF concentrations associated positively with both intimal-media thickness(IMT)(r = 0.24, P = 0.0248) and plaque score(r = 0.27, P =0.0126), indicating a relationship between the elevatedHGF concentrations and advancement of CA involvements. Multivariate statistical analysis accentuated thatserum concentrations of HGF would be associated inde-pendently with IMT(standardized = 0.28, P = 0.0499).The review indicates what is presently known regardingserum HGF might be a new and meaningful biomarkerof macroangiopathy in DM subjects. | Hiroyuki Konya Masayuki Miuchi Kahori Satani Satoshi Matsutani Taku Tsunoda Yuzo Yano Tomoyuki Katsuno Tomoya Hamaguchi Jun-Ichiro Miyagawa Mitsuyoshi Namba | 2014 | World Journal of Diabetes2014，5，5： | 5 |
| 4 | Efficacy of traditional herbal medicines in combination with acyclovir against herpes simplex virus type 1 infection in vitro and in vivo显示文摘 | Masahiko Kurokawa Kazuhiko Nagasaka Tatsuji Hirabayashi Shin-ichi Uyama Hideki Sato Takashi Kageyama Shigetoshi Kadota Haruo Ohyama Toyoharu Hozumi Tsuneo Namba Kimiyasu Shiraki | 1995 | Antiviral Research1995，，1： | 3 |
| 5 | Human hepatocyte carcinogenesis (Review)显示文摘 | Hidenori Shiraha Kazuhide Yamamoto Masayoshi Namba | 2013 | International Journal of Oncology2013，，4： | 3 |
| 6 | Tribulusamide A and B, New Hepatoprotective Lignanamides from the Fruits of Tribulus terrestris: Indications of Cytoprotective Activity in Murine Hepatocyte Culture显示文摘 | Jian-Xin Li Qin Shi Quan-Bo Xiong Jeevan Prasain Yasuhiro Tezuka Toru Hareyama Zheng-Tao Wang Ken Tanaka Tsuneo Namba Shigetoshi Kadota | 1998 | Planta Med1998，，07： | 2 |
| 7 | Erosion in aluminium brazing 显示文摘 | Itoh Y Namba K | 1989 | Sumitomo Light Metal Technical Reports1989，30，2： | 2 |
| 8 | Isolation of new isoflavone from Chinese Pueraria flowers 显示文摘 | Kubo M Sasaki M Namba K | 1975 | Chem Pharm Bull1975，23，10： | 2 |
| 9 | Characterization of a Microhollow Cathode Discharge Plasma in Helium or Air with Water Vapor显示文摘Microhollow cathode discharge (MHCD) plasmas were generated in gas mixtures containing water vapor at pressures of up to 100 kPa of He or 20 kPa of air. The cathode diameter was 1.0 mm with a length of 2.0 mm. The electrical characteristics showed an abnormal glow mode. Spectroscopic measurements were carried out to examine the plasma and radicals. An analysis of the spectral profile of Hα at 656.3 nm enabled a derivation of the electron densities, namely 2×10 14 cm 3 (at 10 kPa) and 6×10 14 cm 3 (at 4 kPa) for the helium and air atmospheres, respectively, in the negative glow region. By comparing the observed OH radical spectra with those calculated by the simulation code LIFBASE, the gas temperature was deduced to be 900 K for 4 kPa of He at a discharge current of 50 mA. | D. FUKUHARA S. NAMBA K. KOZUE T. YAMASAKI K. TAKIYAMA | 2013 | Plasma Science and Technology2013，15，2： | 2 |
| 10 | RET oncogene amplification in thyroid cancer: correlations with radiation-associated and high-grade malignancy显示文摘 | Nakashima M Takamura N Namba H | 2007 | Hum Pathol2007，38，4： | 1 |
| 11 | Hydrothermal dewatering of brown coal and catalytic hydrothermal gasification of the organic compounds dissolving in the water using a novel Ni/carbon catalyst显示文摘 | NAKAGAWA H NAMBA A BOHLMANN M MIURA K | 2004 | Fuel2004，83，6： | 1 |
| 12 | Ameliorating effects of dan-shen and its major ingredient calcium/magnesium lithospermate B on cognitive deficiencies in senescence-accelerated mouse 显示文摘 | Arima T Namba T | 1997 | Nippon Yakurigaku Zasshi1997，110，1： | 1 |
| 13 | Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein 显示文摘 | NAMBA M OKURA T | 1996 | J Immunol1996，156，4： | 1 |
| 14 | The influence of long-term treatment with povidone-iodine on thyroid function显示文摘 | Nobukuni K Hayakawa N Namba R | 1997 | Dermatology1997，1952，： | 1 |
| 15 | Sot-get derived mesoporous silica films using amphiphilic triblock copolymers显示文摘 | KITAZAWA N NAMBA H AONO M | 2003 | Journal of Non-crystalline Solids2003，332，： | 1 |
| 16 | In vivo measurement of acetylcholinesterase activity in the brain with a radioactive acetylcholine analog显示文摘 | Namba H Irie T Fukushi K | 1994 | Brain Res1994，667，： | 1 |
| 17 | 显示文摘 | Namba Naoko Yoshida Yasuhiro Nagaoka Noriyuki | 2009 | Dental Materials2009，25，4： | 1 |
| 18 | Hydrother -mal dewatering of brown coal and catalytic hydrothermal gas- ification of the organic compounds dissolving in the water u- sing a novel Ni/carbon catalyst 显示文摘 | Nakagawa H A Namba M B hlmann | 2004 | Fuel2004，83，6： | 1 |
| 19 | Selective Formation of 2,6-Dimethylnaphthalene from 2-Methylnaphthalene on ZSM-5 and Metallosilicates with MFI Structure 显示文摘 | Komatsu I Araki Y Namba S | 1994 | Stud Surf Sci Catal1994，84，： | 1 |
| 20 | In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs显示文摘 | Oida H Namba T Sugimoto Y | 1995 | Br J Pharmacol1995，116，7： | 1 |
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