|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Function of longitudinal vs circular muscle fibers in esophageal peristalsis, deduced with mathematical modeling显示文摘We summarize from previous works the functions of circular vs. longitudinal muscle in esophageal peristaltic bolus transport using a mix of experimental data, the conservation laws of mechanics and mathematical modeling. Whereas circular muscle tone generates radial closure pressure to create a local peristaltic closure wave, longitudinal muscle tone has two functions, one physiological with mechanical implications, and one purely mechanical. Each of these functions independently reduces the tension of individual circular muscle fibers to maintain closure as a consequence of shortening of longitudinal muscle locally coordinated with increasing circular muscle tone. The physiological function is deduced by combining basic laws of mechanics with concurrent measurements of intraluminal pressure from manometry, and changes in cross sectional muscle area from endoluminal ultrasound from which local longitudinal shortening (LLS) can be accurately obtained. The purely mechanical function of LLS was discovered from mathematical modeling of peristaltic esophageal transport with the axial wall motion generated by LLS. Physiologically, LLS concentrates circular muscle fibers where closure pressure is highest. However, the mechanical function of LLS is to reduce the level of pressure required to maintain closure. The combined physiological and mechanical consequences of LLS are to reduce circular muscle fiber tension and power by as much as 1/10 what would be requiredfor peristalsis without the longitudinal muscle layer, a tremendous benefit that may explain the existence of longitudinal muscle fiber in the gut. We also review what is understood of the role of longitudinal muscle in esophageal emptying, reflux and pathology. | James G Brasseur Mark A Nicosia Anupam Pal Larry S Miller | 2007 | World Journal of Gastroenterology2007，13，9： | 4 |
| 2 | Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice显示文摘 | Lacek K Vercauteren K Grzyb K Naddeo M Verhoye L Slowikowski M P Fafi-Kremer S Patel A H Baumert T F Folgori A Leroux-Roels G Cortese R Meuleman P Nicosia A | 2012 | J Hepatol2012，57，1： | 1 |
| 3 | E- valuating the dynamic behaviour of PROSA P2P network 显示文摘 | NICOSIA V MANGIONI G CARCHIOLO V | 2006 | COMPUTER SCIENCE2006，4，： | 1 |
| 4 | Extending the definition of modularity to directed graphs with overlapping communities 显示文摘 | NICOSIA V MANGIONI G CARCHIOLO V | 2009 | Physics and Society2009，3，4： | 1 |
| 5 | A heuristic approach to batching and scheduling a single machine to minimize setup costs显示文摘 | AGNETIS A ALFIERI A NICOSIA G | 2004 | Computers & Industrial Engineering2004，46，4： | 1 |
| 6 | Extending the definition of modularity to directed graphs with overlapping communities显示文摘 | Nicosia V Mangioni G Carchiolo V | 2009 | J of Statistical Mechanics: Theory and Experiment2009，，3： | 1 |
| 7 | An immune algorithm for protein structure prediction on lattice models显示文摘 | CUTELLO V NICOSIA G PAVONE M | 2007 | IEEE Transactions on Evolutionary Computation2007，11，1： | 1 |
| 8 | Single- machine Scheduling Problems with Generalized Preemption 显示文摘 | Agnetis A Alfieri A Nicosia G | 2009 | Informs Journal on Computing2009，21，1： | 1 |
| 9 | Extending the definition of modularity to directed graphs with overlapping communities显示文摘 | NICOSIA V MANGIONI G CARCHIOLO V | 2009 | J Stat Mech2009，42，3： | 1 |
| 10 | Leukotrienes as mediators of asthma 显示文摘 | Nicosia S Capra V Rovati G E | 2001 | Pulm Parmacol Ther2001，14，1： | 1 |
| 11 | Generalized pattern search algorithm for peptide structure prediction 显示文摘 | NICOSIA G STRACQUADANIO G | 2008 | Biophysical Journal2008，95，10： | 1 |
| 12 | Leukotrlenes as Meditors of Asthma 显示文摘 | NICOSIA S CAPARA V ROVATI G E | 2001 | Pulmonary & Pharmacology & Therapeutics2001，14，： | 1 |
| 13 | An Immune Algorithm for Protein Structure Prediction on Lattice Models显示文摘 | Cutello V Nicosia G | 2007 | IEEE Trans on Evolutionary Computation2007，11，1： | 1 |
| 14 | Paracfine regulation of angiogenesis by different cell types in the aorta ring model显示文摘 | Nicosia RF Zorzi P Ligresti G | | 0，，： | 1 |
| 15 | An evolutionary algorithm-based approach to robust analog circuit design using constrained mul- ti-objective optimization显示文摘 | Nicosia G Rinaudo S Sciacca E | 2008 | Knowledge-based Systems2008，21，3： | 1 |
| 16 | Electrocardiogramgated intravascular ultrasound image acquisition after coronary stent deployment facilitates on-line three dimensional reconstruction and automated lumen quantification显示文摘 | von Birgelen C Mintz G Nicosia A | 1997 | JACC1997，30，2： | 1 |
| 17 | Microvasculature and VEGF expression in cartilaginous tumors显示文摘 | Liu C Nicosia R | 2000 | Hum Pathol2000，31，3： | 1 |
| 18 | Generalized pattern search algorithm for peptide structure prediction 显示文摘 | Nicosia G Stracquadanio | 2008 | Biophysi - cal Journal2008，95，10： | 1 |
| 19 | Larch arabinogalactan for dry eye protection and treatment of corneal lesions: investigations in rabbits 显示文摘 | Burgalassi S Nicosia N Monti D Falcone G Boldrini E Chetoni P | 2007 | J Ocul Pharmacol Ther2007，23，6： | 1 |
| 20 | Leukotrienes as mediators of asthma 显示文摘 | Nicosia S Capra V Rovati G E | 2001 | Pulm Parmacol Ther2001，14，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员