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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Erlotinib in advaneed non-small cell lung cancer: efficacy and safety findings of the global phase IV Tareeva Lung Cancer Survival Treatment study 显示文摘 | Martin R Nico VZ Cesare G | 2010 | J Thoruc Oncol2010，5，10： | 1 |
| 3 | Exact Closed_Form Geolocation for SAR Interferometry显示文摘 | Nico G | 2002 | IEEE Transactions on Geoscience and Remote Sensing2002，40，22： | 1 |
| 4 | A comparison of networks between industry and public sector research in materials technology and biotechnology显示文摘 | Lois P Peter G Nico F | | 0，，03： | 1 |
| 5 | Dynamic molecular structure of plant biomass-derived black carbon (biochar) 显示文摘 | Keiluweit M Nico P S Johnson M G | 2010 | Environmental Science and Technology2010，44，4： | 1 |
| 6 | Review, Thermal water in resources in carbonate rock aquifers显示文摘 | NICO G JUDIT M S ANITA E | 2010 | Hydrogeolo- gy Journal2010，18，6： | 1 |
| 7 | A comparison of networks be- tween industry and public sector research in materials technology and biotechnology 显示文摘 | Lois P Peter G Nico F | 1998 | Research Policy1998，27，3： | 1 |
| 8 | Dynamic molecular structure of plant biomass-derived black carbon(biochar)显示文摘 | KEILUWEIT M NICO P S JOHNSON M G | 2010 | Environmental Science&Technology2010，44，4： | 1 |
| 9 | Organ transplantation and skin cancer: basic problems and new perspectives显示文摘 | Günther F.L.Hofbauer Jan Nico BouwesBavinck SylvieEuvrard | 2010 | Experimental Dermatology2010，，6： | 1 |
| 10 | Analytical Model of Viscoelastic Fluid Dampers显示文摘 | Nicos M Constantinous M C Dargush G F | 1993 | Journal of Structural Engineering1993，119，11： | 1 |
| 11 | A multiagent systemenhancing home-care health services for chronic disease management显示文摘 | VASSILIS'G K IOANNA C NICOS M | 2005 | IEEE Trans-Information Technology in Biomedicine2005，9，4： | 1 |
| 12 | New regularization scheme for phase unwrapping显示文摘 | Guerriero L Nico G Pasquariello G | 1998 | Appl Opt1998，37，14： | 1 |
| 13 | Dynamic molecular structure of plant biomass-derived black carbon(biochar)显示文摘 | KEILUWEIT M NICO P S JOHNSON M G | 2010 | Environmental Science and Technology2010，44，4： | 1 |
| 14 | Dynamic molecular struc- ture of plant biomass-derived black carbon (biochar)显示文摘 | Keiluweit M Nico P S Johnson M G | 2010 | Environmental Science and Technology2010，44，4： | 1 |
| 15 | Temporal Analysis of a Landslide by Means of a Ground-based SAR Interferometer显示文摘 | LEVA D NICO G TARCHI D | 2003 | IEEE Transactions on Geoscience and Remote Sensing2003，41，4： | 1 |
| 16 | Dynamic molecular structure of plant biomass-derived Black Carbon (Biochar) 显示文摘 | KEILUWEIT M NICO P S JOHNSON M G | 2010 | Environmental Science and Technology2010，44，： | 1 |
| 17 | Ana- lytical Model of Viscoelastic Fluid Dampers显示文摘 | Makris Nicos Constantinous M C Dargush G F | 1993 | Journal of Structural Engineering1993，119，11： | 1 |
| 18 | Temporal analysis ofa landslide by means of a ground-based SARinterferometer显示文摘 | LEVA D NICO G TARCHI D | 2003 | IEEE Transactions on Geoscience &Remote Sensing2003，41，4： | 1 |
| 19 | Tissue distribution and membrane localization of aquaporin 9 water channel: evidence for sex-linked differences in liver显示文摘 | Nicchia G P Frigeri A Nico B | 2001 | J Histochem Cytochem2001，49，12： | 1 |
| 20 | Dynamic molecular structure of plant biomass - derived black carbon (bio-char) 显示文摘 | Keiluweit M Nico P S Johnson M G Kleber M | 2010 | Environmental Science & Technology2010，44，4： | 1 |
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