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| 1 | Non-alcoholic fatty liver disease and diabetes: From physiopathological interplay to diagnosis and treatment显示文摘Non-alcoholic fatty liver disease(NAFLD)is highly prevalent in patients with diabetes mellitus and increasing evidence suggests that patients with type 2diabetes are at a particularly high risk for developing the progressive forms of NAFLD,non-alcoholic steatohepatitis and associated advanced liver fibrosis.Moreover,diabetes is an independent risk factor for NAFLD progression,and for hepatocellular carcinoma development and liver-related mortality in prospective studies.Notwithstanding,patients with NAFLD have an elevated prevalence of prediabetes.Recent studies have shown that NAFLD presence predicts the development of type2 diabetes.Diabetes and NAFLD have mutual pathogenetic mechanisms and it is possible that genetic and environmental factors interact with metabolic derangements to accelerate NAFLD progression in diabetic patients.The diagnosis of the more advanced stages of NAFLD in diabetic patients shares the same challenges as in non-diabetic patients and it includes imaging and serological methods,although histopathological evaluation is still considered the gold standard diagnostic method.An effective established treatment is not yet available for patients with steatohepatitis and fibrosis and randomized clinical trials including only diabetic patients are lacking.We sought to outline the published data including epidemiology,pathogenesis,diagnosis and treatment of NAFLD in diabetic patients,in order to better understand the interplay between these two prevalent diseases and identify the gaps that still need to be fulfilled in the management of NAFLD in patients with diabetes mellitus. | Nathalie C Leite Cristiane A Villela-Nogueira Claudia R L Cardoso Gil F Salles | 2014 | World Journal of Gastroenterology2014，20，26： | 21 |
| 2 | Effect of pKa on the kinetics of carbon dioxide absorption in aqueous alkanolamine solutions containing carbonic anhydrase at 298 K 显示文摘 | Nathalie J M C Penders-van E Sylvie F | 2015 | Chemical Engineering Journal2015，259，1： | 1 |
| 3 | Cell - cycle - dependent expression of transforming growth factor β type Ⅰ receptor correlates with differential proliferative effects if TGF - β1 in articular chondrocytes显示文摘 | Nathalie F Jean - Pierre P | 1998 | Experimental cell research1998，243，： | 1 |
| 4 | Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina显示文摘 | Marie-Noelle D Valérie F Nathalie N | 2005 | Mol Vis2005，11，： | 1 |
| 5 | Detection of Microcystin - Producing Cyanobactefia in Missisquoi Bay, Quebec, Canada, Using Quantitative PCR 显示文摘 | Nathalie F Rocio AR Hongmei J | 2010 | Envir Microbiol2010，76，8： | 1 |
| 6 | Angiopoietin-like protein 2 promotes atherogenesis in mice显示文摘 | Nada F Nathalie NT Maya M | | 0，，3： | 1 |
| 7 | Preparation and characterization of poly (amidoaminc) dendrimers functionalized with a rhenium carbonyl complex and PEG as new IR probes for carbonyl metallo immunoassay 显示文摘 | Jan M H Nathalie F D Michele S | 2004 | J Organometallic Chemistry2004，689，25： | 1 |
| 8 | Flavonoids for controlling starch digestion : structural requirements for inhibiting human α - amylase显示文摘 | ELENA LOP HOLGER S NATHALIE F | 2008 | J Med Chem2008，51，12： | 1 |
| 9 | Trace protein,cystain C,2microglobulin,and creatinine compared for detecting impaired glomemlar filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，： | 1 |
| 10 | Glucose hydrogenation on ruthenium catalysts in a trickle-bed reactor 显示文摘 | PIERRE G NATHALIE N GUY F | 1998 | J Catal1998，180，1： | 1 |
| 11 | Self- reported hypertension prevalence and income among older adults in Can- ada and the United States显示文摘 | MARKS K NATHALIE H DAVID F | 2010 | Social Science&Medicine2010，，70： | 1 |
| 12 | β2-Trace protein, cystatin C, β2-Microglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，5： | 1 |
| 13 | Expression of lipoxygenase isoenzymes in developing barley grains显示文摘 | Nathalie F Schmitt Jan R Van Mechelen | 1997 | Plant Science1997，，128： | 1 |
| 14 | Supply chain integration:the role of logistics service providers显示文摘 | NATHALIE F MARIANNE J CHRISTINE R | 2009 | International Journal of Productivity and Performance Management2009，58，1： | 1 |
| 15 | Regulation of acp1, encoding a non-aspartyl acid protease expressed during pathogenesis of Sclerotinia sclerotiorum显示文摘 | SANDRINE C GENEVIEVE B CHRISTINE R MICHEL F | 2001 | Microbiology2001，147，： | 1 |
| 16 | Simplified generation of targeting constructs using ET recombination 显示文摘 | Nathalie Daigle Frank van der Hoeven Hans R Sch?ler Stewart A F | 1999 | Nucleic Acids Res1999，27，17： | 1 |
| 17 | High antifreeze protein levels in wolffish (Anarhichas lupus) make them an ideal candidate for culture in cold, potentially ice laden waters显示文摘 | Marive D Nathalie R L Garth L F | 2007 | Aquaculture2007，272，： | 1 |
| 18 | Geochemical evi- dence(C, N and Pb isotopes)of recent anthropogenic impact in south-central Chile from two environmentally distinct lake sed iment records显示文摘 | Nathalie F Sebastien B Nadine M | 2010 | Journal of Quaternary Science2010，95，7： | 1 |
| 19 | Trace protein, cystain C, β2- microglobulin, and ereatinine compared for detecting impaired glomemlar filtration rates in children 显示文摘 | Guido F Friedrich P Nathalie L | 2002 | Clin Chem2002，48，： | 1 |
| 20 | Identification of pyrazine derivatives in a typical maple syrup using headspace solid-phase microextraction with gas chromatography-mass spectrometry显示文摘 | HASSAN S JACINTHE F NATHALIE M | 2012 | Food chemistry2012，133，： | 1 |
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