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60篇 您的检索式:作者名="Murphy Simon"
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1Low prevalence of epilepsy and onchocerciasis after more than 20 years of ivermectin treatment in the Imo River Basin in Nigeria显示文摘Background:High epilepsy prevalence and incidence have been reported in areas with high onchocerciasis transmission.Recent findings suggest that proper community-directed treatment with ivermectin(CDTI)is potentially able to prevent onchocerciasis-associated epilepsy(OAE).We assessed the epilepsy prevalence and onchocerciasis transmission in two Nigerian villages following more than 20 years of CDTI.Methods:A cross-sectional door-to-door survey was performed in two villages in the Imo River Basin reported to be mesoendomic for onchocerciasis(Umuoparaodu and Umuezeala).Individuals were screened for epilepsy using a validated 5-item questionnaire.Persons suspected to have epilepsy were examined by a neurologist or a physician with training in epilepsy for confirmation.Onchocerciasis was investigated via skin snip microscopy and rapid diagnostic tests for Ov16 antibodies.Results were compared with previous findings from the Imo river basin.Results:A total of 843 individuals from 257 households in the two villages were encountered.We detected four persons with epilepsy(PWE)giving a crude epilepsy prevalence of 0.5%.This finding differs from observations reported 14 years ago which showed an epilepsy prevalence of 2.8%in the neighbouring village of Umulolo(P=0.0001),and 1.2%from 13 villages in the Imo river basin(P=0.07).The seroprevalence of Ov16 antibodies was found to be 0%.Only 4.6%of skin snips were positive compared to 26.8%in previous surveys(P<0.0001).Ivermectin mass distribution coverage in the study sites in 2017 was 79.7%.Conclusions:A low epilepsy and onchocerciasis prevalence was observed following more than 20 years of CDTI in the Imo River Basin.Absence of Ov16 antibodies indicates minimal transmission of onchocerciasis.These results contrast with observations from areas of high onchocerciasis transmission,where epilepsy prevalence and incidence remain high.Findings from this study suggest that sustained efforts could eventually achieve elimination of onchocerciasis in these villages.Joseph N.F.Siewe Chinyere N.Ukaga Ernest O.Nwazor Murphy O.Nwoke Modebelu C.Nwokeji Blessing C.Onuoha Simon O.Nwanjor Joel Okeke Kate Osahor Lilian Chimechefulam Ann I.Ogomaka Augustine A.Amaechi Chika I.Ezenwa Monika N.Ezike Chidimma I.kpeama Ogechi Nwachukwu Austine I.Eriama-Joseph Berthram E.B.Nwoke Robert Colebunders 2019Infectious Diseases of Poverty2019,8,1:2
2Safety and efficacy of perioperative cell salvage and autotransfusion after coronary artery bypass grafting: a randomized trial 显示文摘Gavin J Murphy MD Simon M 2004Ann thorac surg2004,77,:1
3Using simple portable OSL measurements and laboratory charactersation to help understand complex and heterogeneous sediment sequences for luminscence dating显示文摘David C.W Sanderson Simon Murphy 0,,05:1
4Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macmphages 显示文摘Murphy PA Simon PL Willoughby WF 1980J Immunol1980,124,5:1
5Greater apparent absorptionof flavonoids is associated with lesser human fecal flavonoiddisappearance rates显示文摘Simons A L Renouf M Murphy P A 2010J Agric Food Chem2010,58,1:1
6An evaluation of the effectiveness and cost effec- tiveness of the National Exercise Referral Scheme in Wales, UK : a randomised controlled trial of a public health policy ini- tiative 显示文摘Simon Mark Murphy Rhiannon Tudor Edwards Nefyn Wil- liams 2012J Epidemiol Community Health2012,66,:1
7Altered expression of estrogen receptor coregulators during human breast tumorigenesis显示文摘Murphy LC Simon SL Parkes A 2000Cancer Res2000,60,22:1
8Acute variceal haemorrhage in the United Kingdom: Patient characteristics, management and outcomes in a nationwide audit显示文摘Vipul Jairath Sunita Rehal Richard Logan Brennan Kahan Sarah Hearnshaw Simon Stanworth Simon Travis Michael Murphy Kelvin Palmer Andrew Burroughs 2013Digestive and Liver Disease2013,,:1
9Sex Differences in the Causes of Adolescent Suicide Ideation显示文摘Simons R L Murphy P I 1985Journal of Youth and Adolescence1985,14,5:1
10Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macrophages显示文摘Murphy PA Simon PL Willoughby WF 1980J Immunol1980,124,5:1
11Fertility decline,ba-by boom,and economic growth显示文摘Murphy K Simon C Tamura R 2008Journal of HumanCapital2008,2,3:1
12Soyasaponins lowered plasma cholesterol and increased fecal bile acids in female golden Syrian hamsters显示文摘Lee S O Simons A L Murphy P A 2005Experimental Biology and Medicine2005,230,7:1
13Altered expression of estrogen receptor coregulators during human breast tumorigenesis 显示文摘Murphy L C Simon S L Parkes A 2000Cancer Res2000,60,22:1
14Intangible benefits valuation in ERP project显示文摘MURPHY K E SIMON S J 2002Information Systems Journal2002,12,4:1
15Femoral anteversion显示文摘Murphy SB Simon SR Kijewski PK 1987J Bone Joint Surg1987,69,8:1
16Intangible benefits valuation in ERP projects 显示文摘Murphy J C Simon S J 2002Information Systems Journal2002,12,4:1
17Femoral anteversion显示文摘Murphy SB Simon SR Kijewski PK 1987J Bone Joint Surg1987,67,:1
18Pancreatic resection:a key component to reducing racial disparities in pancreatic adenocarcinoma显示文摘Murphy MM Simons JP Hill JS 2009Cancer2009,115,17:1
19Greater apparent ab- sorption of flavonoids is associated with lesser human fecal fla-vonoid disappearance rates 显示文摘Simons A L Renouf M Murphy P A 2010J Agric Food Chem2010,58,1:1
20Paternal influence of sperm DNA integrity on early embryonic development 显示文摘Simon L Murphy K Shamsi MB 2014Human Repro- duction ( Oxford England)2014,29,11:1
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