|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | HCV-specific cytokine induction in monocytes of patients with different outcomes of hepatitis C显示文摘AIM:Cytokine release by macrophages critically determines the type of immune response to an antigen Therefore.we studied hepatitis C virus (HCV0-Specific induction of interleukins-1β,-10,-12(IL-1β,il-10,IL-12),and tumor necrosis factor-α(TNF-α) in monocytes.METHODS:Intracellular cytokine expression was studied by flow cytometry in 23 patients with chronic hepatitis C,14 anti-HCV seropositives without viremia and 11 controls after stimulation of peripheral blood mononuclear cells with recombinant core,NS3,NS4 NS5a and NS5b proteins .RESULTS:Patients with HCV viremia revealed greater spontaneous exprssion of IL-1β,TNF-α,and IL-10,Furthermore,greater than twofold higher IL-10 epression was induced by the HCV antigens in chronic hepatitis C than in the other two groups (P<0.05) In contrast,neither IL-12 noir TNF-α was induced preferentially.CONCLUSION:In chonic hepatitis C antigen-specific cytokine induction in monocytes is apparently shifted towards predominant IL-10 induction-not counterbalanced by antiviral type 1 cytokines,This may contribute to persistent viral replication. | Rainer P.Woitas Uwe Petersen Dirk Moshage Hans H.Brackmann Bertfried Matz Tilman Sauerbruch Ulrich Spengler | 2002 | World Journal of Gastroenterology2002，8，3： | 15 |
| 2 | Glutathione and antioxidant enzymes serve complementary roles in protecting activated hepatic stellate cells against hydrogen peroxide-induced cell death显示文摘 | Sandra Dunning Atta ur Rehman Marjolein H. Tiebosch Rebekka A. Hannivoort Floris W. Haijer Jannes Woudenberg Fiona A.J. van den Heuvel Manon Buist-Homan Klaas Nico Faber Han Moshage | 2013 | BBA - Molecular Basis of Disease2013，，： | 2 |
| 3 | Hepatocyte oxidant stress and alcoholic liver disease显示文摘 | CONDE DE LA ROSA L MOSHAGE H NIETO N | 2008 | Rev Esp Enferm Dig2008，100，3： | 1 |
| 4 | Detection of high-grade restenosis after PTCA using contrast-enhanced electron beam CT 显示文摘 | Moshage W | 1997 | Circulation1997，96，9： | 1 |
| 5 | Electron beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients显示文摘 | Braun J Oldendort M Moshage W | 1996 | Am J Kidney Dis1996，27，3： | 1 |
| 6 | Electron beam computed tomography in the evaluation of cardiac calcifications in chronic dialysis patients显示文摘 | Braun J Oldendorf M Moshage W | 1996 | Am J Kidney Dis1996，27，3： | 1 |
| 7 | CytoSines and the hepatic acute phase response显示文摘 | Moshage H | 1997 | J Pathol1997，181，： | 1 |
| 8 | Nitrite and nitrate determinations in plasma: a critical evaluation显示文摘 | Moshage H Kok B Huizenga JR | 1995 | Clin Chem1995，41，61： | 1 |
| 9 | Comparison of contrast enhanced electron beam CT and coronary angiography in 125 patients 显示文摘 | Achenhach S Moshage W Roperts D | 1998 | J Am Coll Cardiol1998，31，： | 1 |
| 10 | Nitrite and nitrate determinations in plasma:a critical evaluation显示文摘 | Moshage H Kok B Huizenga JR | 1995 | Clin Chem1995，41，61： | 1 |
| 11 | A long- term hepatitis B vlremia model generated by transplanting nontumrlgenic immortalized human hepatocytes in Rag-2-deficient mice 显示文摘 | Brown JJ Parashar B Moshage H | 2000 | Hepatology2000，31，： | 1 |
| 12 | Recommendations for standardization of EBT and MSCT scanning显示文摘 | Achenbach S Daniel WG Moshage W | 2001 | Herz2001，26，： | 1 |
| 13 | Visualizationof coronart artery anomalies and their anatomic course by contrast-enhanced electron beam tomography and three-dimensional reconstruction显示文摘 | MOshage W Daniel WG | 2001 | Am J Cardiol2001，87，： | 1 |
| 14 | Cytokines and the hepatic acute phase response显示文摘 | Han Moshage | 1997 | J Pathol1997，181，3： | 1 |
| 15 | Braindeath induces apoptosis in donor liver of the rat 显示文摘 | Van Der Hoeven JA Moshage H Schuurs T | 2003 | Transplantation2003，76，8： | 1 |
| 16 | Hepatitis C virus RNAs in plasma-and in peripheral blood mononuclear cells of hemophiliacs with chronic hepatitis C:evidence for viral replication in peripheral blood mononuclear cells显示文摘 | Willems M Peerlinck K Moshage H Deleu I Van den Eynde C Vermylen J Yap SH | | 0，，： | 1 |
| 17 | Electron beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients显示文摘 | Braun J Oldendorf M Moshage W | 1996 | Am J Kidney1996，27，： | 1 |
| 18 | Blockade of NF-kappaB activation and donation of nitric oxide: new treatment options in inflammatory bowel disease?显示文摘 | Dijkstra G Moshage H Jansen PL | 2002 | Scand J Gastroenterol Suppl2002，236，： | 1 |
| 19 | Visualization of coronary artery snomalies and their anatomic course by contrast-enhanced electron beam tomography and three-dimensional reconstruction 显示文摘 | Moshage W Daniel WG | 2001 | Am J Cardiol2001，87，2： | 1 |
| 20 | Electron beam computed tomography in the evaluation of cardiac calci- fication in chronic dialysis patients显示文摘 | Braun J Oldendorf M Moshage W | 1996 | Am J Kidney Dis1996，27，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员