|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Genomic prediction of fruit texture and training population optimization towards the application of genomic selection in apple显示文摘Texture is a complex trait and a major component of fruit quality in apple.While the major effect of MdPG1,a gene controlling firmness,has already been exploited in elite cultivars,the genetic basis of crispness remains poorly understood.To further improve fruit texture,harnessing loci with minor effects via genomic selection is therefore necessary.In this study,we measured acoustic and mechanical features in 537 genotypes to dissect the firmness and crispness components of fruit texture.Predictions of across-year phenotypic values for these components were calculated using a model calibrated with 8,294 SNP markers.The best prediction accuracies following cross-validations within the training set of 259 genotypes were obtained for the acoustic linear distance(0.64).Predictions for biparental families using the entire training set varied from low to high accuracy,depending on the family considered.While adding siblings or half-siblings into the training set did not clearly improve predictions,we performed an optimization of the training set size and composition for each validation set.This allowed us to increase prediction accuracies by 0.17 on average,with a maximal accuracy of 0.81 when predicting firmness in the‘Gala’בPink Lady’family.Our results therefore identified key genetic parameters to consider when deploying genomic selection for texture in apple.In particular,we advise to rely on a large training population,with high phenotypic variability from which a‘tailored training population’can be extracted using a priori information on genetic relatedness,in order to predict a specific target population. | Morgane Roth Hélène Muranty Mario Di Guardo Walter Guerra Andrea Patocchi Fabrizio Costa | 2020 | Horticulture Research2020，7，1： | 4 |
| 2 | Characterization of 14-3-3proteins in adrenal chromaffin cells and demonstration of isoformspecific phospholipid binding显示文摘 | Roth D Morgan A Martin H | 1994 | Biochem J1994，301，1： | 1 |
| 3 | Analysis of intracellular protein function by antibody injection显示文摘 | Morgan DO Roth RA | 1988 | Immunol Today1988，9，3： | 1 |
| 4 | Microglial Activation is Required for Aβ Clearance After Intracranial Injection of Lipopolysaccharide in APP Transgenic Mice显示文摘 | Donna L. Herber Mary Mercer Lisa M. Roth Keisha Symmonds Jessica Maloney Nedda Wilson Melissa J. Freeman Dave Morgan Marcia N. Gordon | 2007 | Journal of Neuroimmune Pharmacology2007，，： | 1 |
| 5 | Covalent protein-oligonucleotide conjugates for efficient delivery of antisense molecules显示文摘 | Rajur SB Roth CM Morgan JR | | 0，，： | 1 |
| 6 | Analysis of intracellular mDtein function by antibody injectian 显示文摘 | Morgan DO Roth RA | 1988 | Immunol Today1988，9，3： | 1 |
| 7 | Covalent protein-oligonucleotide conjugates for efficient delivery of antisense molecules显示文摘 | Rajur SB Roth CM Morgan JR | 1997 | Bioconjug Chem1997，8，6： | 1 |
| 8 | The apple REFPOP—a reference population for genomics-assisted breeding in apple显示文摘Breeding of apple is a long-term and costly process due to the time and space requirements for screening selection candidates.Genomics-assisted breeding utilizes genomic and phenotypic information to increase the selection efficiency in breeding programs,and measurements of phenotypes in different environments can facilitate the application of the approach under various climatic conditions.Here we present an apple reference population:the apple REFPOP,a large collection formed of 534 genotypes planted in six European countries,as a unique tool to accelerate apple breeding.The population consisted of 269 accessions and 265 progeny from 27 parental combinations,representing the diversity in cultivated apple and current European breeding material,respectively.A high-density genome-wide dataset of 303,239 SNPs was produced as a combined output of two SNP arrays of different densities using marker imputation with an imputation accuracy of 0.95.Based on the genotypic data,linkage disequilibrium was low and population structure was weak.Two well-studied phenological traits of horticultural importance were measured.We found marker–trait associations in several previously identified genomic regions and maximum predictive abilities of 0.57 and 0.75 for floral emergence and harvest date,respectively.With decreasing SNP density,the detection of significant marker–trait associations varied depending on trait architecture.Regardless of the trait,10,000 SNPs sufficed to maximize genomic prediction ability.We confirm the suitability of the apple REFPOP design for genomics-assisted breeding,especially for breeding programs using related germplasm,and emphasize the advantages of a coordinated and multinational effort for customizing apple breeding methods in the genomics era. | Michaela Jung Morgane Roth Maria JoséAranzana Annemarie Auwerkerken Marco Bink Caroline Denancé Christian Dujak Charles-Eric Durel Carolina Font i Forcada Celia M.Cantin Walter Guerra Nicholas P.Howard Beat Keller Mariusz Lewandowski Matthew Ordidge Marijn Rymenants Nadia Sanin Bruno Studer Edward Zurawicz François Laurens Andrea Patocchi Hélène Muranty | 2020 | Horticulture Research2020，7，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员