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| 1 | Treatment of acute periprosthetic infections with prosthesis retention: Review of current concepts显示文摘Periprosthetic joint infection(PJI) is a devastating complication after total joint arthroplasty, occurring in approximately 1%-2% of all cases. With growing populations and increasing age, PJI will have a growing effect on health care costs. Many risk factors have been identified that increase the risk of developing PJI, including obesity, immune system deficiencies, malignancy, previous surgery of the same joint and longer operating time. Acute PJI occurs either postoperatively(4 wk to 3 mo after initial arthroplasty, depending on the classification system), or via hematogenous spreading after a period in which the prosthesis had functioned properly. Diagnosis and the choice of treatment are the cornerstones to success. Although different definitions for PJI have been used in the past, most are more or less similar and include the presence of a sinus tract, blood infection values, synovial white blood cell count, signs of infection on histopathological analysis and one ormore positive culture results. Debridement, antibiotics and implant retention(DAIR) is the primary treatment for acute PJI, and should be performed as soon as possible after the development of symptoms. Success rates differ, but most studies report success rates of around 60%-80%. Whether single or multiple debridement procedures are more successful remains unclear. The use of local antibiotics in addition to the administration of systemic antibiotic agents is also subject to debate, and its pro's and con's should be carefully considered. Systemic treatment, based on culture results, is of importance for all PJI treatments. Additionally, rifampin should be given in Staphylococcal PJIs, unless all foreign material is removed. The most important factors contributing to treatment failure are longer duration of symptoms, a longer time after initial arthroplasty, the need for more debridement procedures, the retention of exchangeable components, and PJI caused by Staphylococcus(aureus or coagulase negative). If DAIR treatment is unsuccessful, the following treatment option should be based on the patient health status and his or her expectations. For the best functional outcome, one- or two-stage revision should be performed after DAIR failure. In conclusion, DAIR is the obvious choice for treatment of acute PJI, with good success rates in selected patients. | Jesse WP Kuiper Robin Tjeenk Willink Dirk Jan F Moojen Michel PJ van den Bekerom Sascha Colen | 2014 | World Journal of Orthopedics2014，5，5： | 12 |
| 2 | Postoperative weight gain after standard Whipple's procedure versus pylorus-preserving pancreaticoduodenectomy:the influence of tumour status显示文摘 | Van Berge Henegouwen MI Moojen TM van Gulik TM | 1998 | Br J Surg1998，85，： | 2 |
| 3 | lnterspinous process device versus standard conventional surgical decompression for lumbar spinal stenosis:randomized controlled trial显示文摘 | Moojen WA Arts MP Jacobs WC | 2013 | BMJ2013，347，： | 1 |
| 4 | In vivo analysis of carpal kin-ematics and comparative review of the literature显示文摘 | Moojen TM Snel JG Ritt MJ et a1 | | 0，，： | 1 |
| 5 | Scaphoid kinematics in vivo显示文摘 | Moojen TM Snel JG Ritt MJPF | 2002 | J Hand Surg2002，27，： | 1 |
| 6 | ldentification of orthopaedic infections using broad-range polymerase chain reaction and reverse line blot hybridization显示文摘 | Moojen DJ Spijkers SN Schot CS | 2007 | J Bone Joint Surg Am2007，89，6： | 1 |
| 7 | Three-dimensional carpal kinematics in vivo显示文摘 | Moojen TM Snel JG Ritt MJPF | 2002 | Clin Biomech2002，17，： | 1 |
| 8 | Identification of orthopaedic infections using broad-range polymerase chain reaction and reverse line blot hybridization显示文摘 | Moojen DJ Spijkers SN Schot CS | 2007 | J Bone Joint Surg Am2007，89，6： | 1 |
| 9 | Prophylaxis of infection and effects on osseointegration using a tobramycin-periapatite coating on titanium implants- an experimental study in the rabbit显示文摘 | Moojen D J Vogely HC Fleer A | 2009 | J Orthop Res2009，27，6： | 1 |
| 10 | Canine motility and gastric emptying after subtotal gasttectomy显示文摘 | Wan Brage Henegouwen MI Vain Culik TH Moojen TM | 1998 | Am J Surg1998，225，4： | 1 |
| 11 | Differential diagnosis of focal pancreatitis and pancreatic cancer显示文摘 | van Gulik TM Moojen TM van Geenen R | 1999 | Ann Oncol1999，10，4： | 1 |
| 12 | Antimi- crobial activity of platelet-leukocyte gel against Staphylococcus aureus显示文摘 | MOOJEN D J EVERTS P A SCHURE R M | 2008 | J Orthop Res2008，26，3： | 1 |
| 13 | Antimicrobial activity of platelet-leukocytc gel against staphylococcus aureus 显示文摘 | Moojen D J Everts P A Schure R M | 2008 | J Orthop Res2008，26，3： | 1 |
| 14 | Antimicrobial activity of platelet-leukocyte gel against Staphylococcus aureus显示文摘 | Moojen DJ Everts PA Schure RM | 2008 | J Orthop Res2008，26，3： | 1 |
| 15 | Long-term results: adjuvant radiotherapy in en bloc resection of sacrococcygea chordoma is advisable显示文摘 | Moojen WA Vleggeert-Lankamp CL Krol AD | 2011 | Spine2011，36，10： | 1 |
| 16 | In vivo analysis of carpal kinematics and comparative review of the literature显示文摘 | Moojen TM Snel JG Ritt MJ | 2003 | J Hand Surg2003，，3： | 1 |
| 17 | Two-stage revision arthroplasty for coagulase-negative staphylococcal periprosthetic joint infection of the hip and knee显示文摘BACKGROUND Periprosthetic joint infections(PJIs)are frequently caused by coagulase-negative Staphylococci(CoNS),which is known to be a hard-to-treat microorganism.Antibiotic resistance among causative pathogens of PJI is increasing.Two-stage revision is the favoured treatment for chronic CoNS infection of a hip or knee prosthesis.We hypothesised that the infection eradication rate of our treatment protocol for two-stage revision surgery for CoNS PJI of the hip and knee would be comparable to eradication rates described in the literature.AIM To evaluate the infection eradication rate of two-stage revision arthroplasty for PJI caused by CoNS.METHODS All patients treated with two-stage revision of a hip or knee prosthesis were retrospectively included.Patients with CoNS infection were included in the study,including polymicrobial cases.Primary outcome was infection eradication at final follow-up.RESULTS Forty-four patients were included in the study.Twenty-nine patients were treated for PJI of the hip and fifteen for PJI of the knee.At final follow-up after a mean of 37 mo,recurrent or persistent infection was present in eleven patients.CONCLUSION PJI with CoNS can be a difficult to treat infection due to increasing antibiotic resistance.Infection eradication rate of 70%-80%may be achieved. | Ewout S Veltman Dirk Jan F Moojen Marc L van Ogtrop Rudolf W Poolman | 2019 | World Journal of Orthopedics2019，10，10： | 1 |
| 18 | Effectiveness of in- terspinous implant surgery in patients with intermittent neuro- genicclaudication: a systematic review and meta-analysis 显示文摘 | Moojen WA Arts MP Bartels RH | 2011 | Eur Spine J2011，120，10： | 1 |
| 19 | Antimicrobial activity of platelet-leukocyte gel against Staphylococcus aureus显示文摘 | Moojen DJ Everts PA Schure RM | | 0，，03： | 1 |
| 20 | Postoperative weight gain after standard Whipple's procedure versus pylorus-presorving pancreatoduodenectomy:The influence of tumour status显示文摘 | van Berge Henegouwen MI Moojen TM van Gulik TM | 1998 | Br J Surg1998，85，7： | 1 |
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