6篇
您的检索式：作者名="Montero CI"
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| 1 | Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme显示文摘 | Lorda-Diez CI Montero JA Martinez-Cue C | | 0，，43： | 1 |
| 2 | Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme显示文摘 | Lorda-Diez CI Montero JA Martinez-Cue C | 2009 | J Biol Chem2009，284，29： | 1 |
| 3 | Ligand-and Stage-Dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro显示文摘 | Lorda-Diez CI Montero JA Choe SA | 2014 | J Bone Miner Res2014，29，3： | 1 |
| 4 | Genomewide recombination drives diversification of epidemic strains of Acinetobacter baumannii 显示文摘 | Snitkin ES Zelazny AM Montero CI | 2011 | Proc Natl Aead Sci USA2011，108，13： | 1 |
| 5 | Interdigital cell death in the embryonic limb is associated with depletion of Reelin in the extracellular matrix 显示文摘 | Diaz- Mendoza M J Lorda- Diez CI Montero JA | 2013 | Cell Death Dis2013，4，： | 1 |
| 6 | Macrometastasis at selective lymph node biopsy:A practical goingfor-the-one clinical scoring system to personalize decision making显示文摘BACKGROUND Axillary sentinel lymph node biopsy(SLNB)is standard treatment for patients with clinically and pathological negative lymph nodes.However,the role of completion axillary lymph node dissection(cALND)following positive sentinel lymph node biopsy(SLNB)is debated.AIM To identify a subgroup of women with high axillary tumor burden undergoing SLNB in whom cALND can be safely omitted in order to reduce the risk of longterm complications and create a Preoperative Clinical Risk Index(PCRI)that helps us in our clinical practice to optimize the selection of these patients.METHODS Patients with positive SLNB who underwent a cALND were included in this study.Univariate and multivariate analysis of prognostic and predictive factors were used to create a PCRI for safely omitting cALND.RESULTS From May 2007 to April 2014,we performed 1140 SLN biopsies,of which 125 were positive for tumor and justified to practice a posterior cALND.Pathologic findings at SLNB were micrometastases(mic)in 29 cases(23.4%)and macrometastasis(MAC)in 95 cases(76.6%).On univariate analysis of the 95 patients with MAC,statistically significant factors included:age,grade,phenotype,histology,lymphovascular invasion,lymph-node tumor size,and number of positive SLN.On multivariate analysis,only lymph-node tumor size(≤20 mm)and number of positive SLN(>1)retained significance.A numerical tool was created giving each of the parameters a value to predict preoperatively which patients would not benefit from cALND.Patients with a PCRI≤15 has low probability(<10%)of having additional lymph node involvement,a PRCI between 15-17.6 has a probability of 43%,and the probability increases to 69%in patients with a PCRI>17.6.CONCLUSION The PCRI seems to be a useful tool to prospectively estimate the risk of nodal involvement after positive SLN and to identify those patients who could omit cALND.Further prospective studies are necessary to validate PCRI clinical generalization. | Mercedes Herrero Raquel Ciérvide Maria Elisa Calle-Purón Javier Valero Paula Buelga Isabel Rodriguez-Bertos Leticia Benassi Angel Montero | 2021 | World Journal of Clinical Oncology2021，12，8： | 0 |
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