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| 1 | Toll-like receptor expression and signaling in human diabetic wounds显示文摘AIM: To examine the contribution of toll-like receptors(TLRs) expression and activation to the prolonged inflammation often seen in human diabetic wounds.METHODS: Debridement wound tissue was collected from diabetic patients with informed consent. Total RNA and protein were isolated and subjected to real-time polymerase chain reaction and Western blot analyses. RESULTS: TLR1, 2, 4, and 6 mRNA expressions were increased significantly in wounds of diabetic patients compared with non-diabetic wounds(P < 0.05). MyD88 protein expression was significantly increased in diabetic wounds compared to non-diabetic wounds. Interleukin-1beta, tumor necrosis factor-alpha concentration nuclear factor-kappa B activation, and thiobarbituric acid reactive substances were increased in diabetic wounds compared to non-diabetic wounds(P < 0.01). CONCLUSION: Collectively, our novel findings show that increased TLR expression, signaling, and activation may contribute to the hyper inflammation in the human diabetic wounds. | Mohan R Dasu Sandra J Martin | 2014 | World Journal of Diabetes2014，5，2： | 2 |
| 2 | Treatment of simulated Reactive Yellow 22 (Azo) dye effluents using Spirogyra species 显示文摘 | Mohan S V Rao N C Prasad K K J | 2002 | Waste Management2002，22，6： | 1 |
| 3 | Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology显示文摘 | Mohan VP Scanga CA Yu K Scott HM Tanaka KE Tsang E Tsai MM Flynn JL Chan J | 2001 | Infect Immune2001，69，3： | 1 |
| 4 | Effects of cadmium salt on phosphomonoesterases activity and fertilizing ability of fowl spermatozoa显示文摘 | Mohan J Moudgal R P Panda J N | 1992 | Indian J Experi Biol1992，30，： | 1 |
| 5 | 查看详情显示文摘 | Mohan P Motohisa J Fukui T | | 0，，： | 1 |
| 6 | Compensation differences between male and female CEOs for publicly traded firms: a nonparametric analysis 显示文摘 | Mohan N Ruggiero J | 2003 | Journal of the Operational Research Society2003，54，： | 1 |
| 7 | Financial benefits from JIT Adoption:Effects of Customer Concentration and Cost Structure显示文摘 | RAMJI B THOMAS J L MOHAN V | 1996 | Accounting Review1996，71，2： | 1 |
| 8 | Treatment of Simulated Reactive Yellow 22 (Azo) Dye Effluents Using Spirogyra Species 显示文摘 | VENKATA MOHAN S CHANDRASEKHAR RAO N KRISHNA PRASAD K KARTHIKEYAN J | 2002 | Waste Management2002，22，： | 1 |
| 9 | Changes in protein synthesis during drought conditioning in roots of jack pine seedlings 显示文摘 | Michael B M Mohan S Terence J B | 1994 | Tree Physiology1994，14，： | 1 |
| 10 | Apoptosis, necrosis, proliferation, and myofibroblast generation in the stroma following LASIK and PRK显示文摘 | Mohan RR Hutcheon AE Choi R Hong J Lee J Mohan RR | 2003 | Exp Eye Res2003，76，： | 1 |
| 11 | Effects of malate, lactate, and pyruvate on myoglobin redox stability in homogenates of three bovine muscles显示文摘 | MOHAN A HUNT M C BARSTOW T J | 2010 | Meat Science2010，86，2： | 1 |
| 12 | Analysis of integrated solenoid inductor with closed magnetic core 显示文摘 | WRIGHT J M LEE D W MOHAN Av | 2010 | IEEE Transactions on Magnetics2010，46，： | 1 |
| 13 | Band parameters for Ⅲ-V compound semiconductors and their alloys 显示文摘 | Vurqaftman I Meyer J R Mohan L R R | 2001 | J Appl Phys2001，89，11： | 1 |
| 14 | Semi-IPNs of starch and poly (aerylamide-eo-sodium methacrylate) : Preparation, swelling and diffusion characteristics evaluation 显示文摘 | Keshava Murthy P S Murali Mohan Y Sreeramulu J | 2006 | Reactive & Functional Polymers2006，66，： | 1 |
| 15 | Nanocellulose reinforced PVA composite films Effects of acid treatment and filler loading显示文摘 | Lee S Y Mohan D J Kang I A | 2009 | Fibers and Polymers2009，10，1： | 1 |
| 16 | Hepatocyte growth factor and hepatocyte growth factor receptor in the lacrimal gland,tears,and cornea显示文摘 | Li Q Weng J Mohan R R | 1996 | Invest Ophthalmol Vis Sci1996，37，5： | 1 |
| 17 | Control strategies for dynamic voltage restorer compensating voltage sags with phase jump显示文摘 | Nielsen J G Blaabjerg F Mohan N | 2001 | Conference Proceedings of IEEE Applied Power Electronic Conference and Exposition APEC IEEE2001，2，21： | 1 |
| 18 | Sequential coding algorithms: a survey and cost analysis显示文摘 | ANDERSON J B MOHAN S | 1984 | IEEE Trans Commun1984，32，2： | 1 |
| 19 | Effects of cadmium salt on phosphomonoes terases activity and fertilizing ability of fowl spermatozoa 显示文摘 | Mohan J Mrudgal R P Panda J N | 1992 | Indian Journal of Experimental Biol- ogy1992，30，3： | 1 |
| 20 | IL-1 upregulates kerattnocyte growth factor and hepatocyte growth factor mRNA and protein production by cultured stromal fibroblast cells: interleukin-1 beta expression in the cornea显示文摘 | Weng J Mohan RR Li Q Wilson SE | 1997 | Cornea1997，16，4： | 1 |
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