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| 1 | Using induced pluripotent stem cells as a tool for modelling carcinogenesis显示文摘Cancer is a highly heterogeneous group of diseases that despite improved treatments remain prevalent accounting for over 14 million new cases and 8.2 million deaths per year. Studies into the process of carcinogenesis are limited by lack of appropriate models for the development and pathogenesis of the disease based on human tissues. Primary culture of patient samples can help but is difficult to grow for a number of tissues. A potential opportunity to overcome these barriers is based on the landmark study by Yamanaka which demonstrated the ability of four factors;Oct4, Sox2, Klf4, and c-Myc to reprogram human somatic cells in to pluripotency. These cells were termed induced pluripotent stem cells(i PSCs) and display characteristic properties of embryonic stem cells. This technique has a wide range of potential uses including disease modelling, drug testing and transplantation studies. Interestingly i PSCs also share a number of characteristics with cancer cells including self-renewal and proliferation, expression of stem cell markers and altered metabolism. Recently, i PSCs have been generated from a number of human cancer cell lines and primary tumour samples from a range of cancers in an attempt to recapitulate the development of cancer and interrogate the underlying mechanisms involved. This review will outline the similarities between the reprogramming process and carcinogenesis, and how these similarities have been exploited to generate i PSC models for a number of cancers. | Emma L Curry Mohammad Moad Craig N Robson Rakesh Heer | 2015 | World Journal of Stem Cells2015，7，2： | 5 |
| 2 | Discontinuous rock slope stability analysis by limit equilibrium approaches–a review显示文摘Slope stability is one of the most important topics of engineering geology with a background of more than 300 years.So far,various stability assessment techniques have been developed which include a range of simple evaluations,planar failure,limit state criteria,limit equilibrium analysis,numerical methods,hybrid and high-order approaches which are implemented in two-dimensional(2D)and three-dimensional(3D)space.In the meantime,limit equilibrium methods due to their simplicity,short analysis time,coupled with probabilistic and statistics functions to estimate the safety factor(F.S),probable slip surface,application on different failure mechanisms,and varied geological conditions has been received special attention from researchers.The presented paper provides a review to limit equilibrium methods used for discontinuous rock slope stability analyses with different failure mechanisms of natural and cut slopes.The article attempted to provide a systematic review for rock slope stability analysis outlook based on limit equilibrium approaches. | Mohammad Azarafza Haluk Akgün Akbar Ghazifard Ebrahim Asghari-Kaljahi Jafar Rahnamarad Reza Derakhshani | 2021 | International Journal of Digital Earth2021，14，12： | 5 |
| 3 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | 2012 (9859)2012，，9859： | 3 |
| 4 | Langerhans cell histiocytosis masquerading as acute appendicitis: Case report and review显示文摘Langerhans cell histiocytosis(LCH) is a rare syndrome characterized by unifocal,multifocal unisystem,or disseminated/multi-system disease that commonly involves the bone,skin,lymph nodes,pituitary,or sometimes lung(almost exclusively in smokers) causing a variety of symptoms from rashes and bone lesions to diabetes insipidus or pulmonary infiltrates.We present a previously unreported case of gastrointestinal LCH as well as a novel characteristic lesion affecting the colon of a young woman who presented with signs and symptoms mimicking acute on chronic appendicitis.Immunohistochemical analysis of appendectomy specimen and nodular specimens on colonoscopy demonstrated S-100,CD1a,and langerin reactivity.The patient underwent systemic chemotherapy with cytarabine and demonstrated excellent response to therapy. | Mohammad M Karimzada Michele N Matthews Samuel W French Daniel De Ugarte Dennis Y Kim | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，3： | 3 |
| 5 | Interactive Effect of GA_3 ,N and P Ameliorate Growth, Seed and Fibre Yield by Enhancing Photosynthetic Capacity and Carbonic Anhydrase Activity of Linseed: A Dual Purpose Crop显示文摘Linseed (Linum usitatissimum L.) is an important dual-purpose, industrial crop. Its seeds are used for the extraction of oil and stem for fibres. However, the production of linseed is not going parallel with the increasing demand of its products. The present work was carried out with an aim to find out whether exogenous application of gibberellic acid (GA3) with or without graded levels of nitrogen (N) and phosphorus (P) could improve the performance of three linseed genotypes Parvati, Shekhar and Shubhra together with minimizing the costly fertilizer input and losses. Four combinations of N and P, viz., 0 mg N+0 mg P kg-1 soil (N0P0), N13.4 P4.46 , N26.8P8.94 and N40.2P13.4 were constituted. Half dose of each combination was applied basally at the time of sowing and remaining half dose was given at 40 d after sowing (DAS) as foliar spray along with 10-6 mol L-1 GA3 . Prior to sowing, the seeds of each linseed genotype were grouped in to two, one group of seeds was soaked in 0 mol L-1 GA3 (control) and the other group was soaked in 10-6 M GA3 solution, each for 8 hours. Treatments were comprised of (i) 0 mol L-1 GA3+N0P0 (T0 , control), (ii) 10-6 mol L-1 GA3 + N13.4P4.46 (T1), (iii) 10-6 mol L-1 GA 3 +N 26.8 P 8.94 (T2) and (iv) 10-6 mol L-1 GA3+N40.2P13.4 (T3). The crop performance was assessed in terms of growth, physiological and biochemical parameters at 60 and 75 DAS and yield attributes at harvest (175 DAS). The results showed a parallel increase in most of the parameters with increasing levels of N and P. However, application of 10-6 mol L-1 GA3 in association with N26.8P8.94 proved best, it enhanced seed yield, oil yield and fibre yield by 83.3, 97.3 and 78.7%, respectively accompanied with increase in net photosynthetic rate, carbonic anhydrase activity and dry matter accumulation. Among the genotypes tested, Shubhra performed best, while Parvati the least for most of the parameters studied. Thus, combined application of 10-6 mol L-1 GA3 plus N26.8P8.94 proved best and can be recommended to exploit the linseed as a dual-purpose crop for good yield of seed and fibre. | Mohammad N Khan Firoz Mohammad | 2013 | Journal of Integrative Agriculture2013，12，7： | 2 |
| 6 | Archery Algorithm:A Novel Stochastic Optimization Algorithm for Solving Optimization Problems显示文摘Finding a suitable solution to an optimization problem designed in science is a major challenge.Therefore,these must be addressed utilizing proper approaches.Based on a random search space,optimization algorithms can find acceptable solutions to problems.Archery Algorithm(AA)is a new stochastic approach for addressing optimization problems that is discussed in this study.The fundamental idea of developing the suggested AA is to imitate the archer’s shooting behavior toward the target panel.The proposed algorithm updates the location of each member of the population in each dimension of the search space by a member randomly marked by the archer.The AA is mathematically described,and its capacity to solve optimization problems is evaluated on twenty-three distinct types of objective functions.Furthermore,the proposed algorithm’s performance is compared vs.eight approaches,including teaching-learning based optimization,marine predators algorithm,genetic algorithm,grey wolf optimization,particle swarm optimization,whale optimization algorithm,gravitational search algorithm,and tunicate swarm algorithm.According to the simulation findings,the AA has a good capacity to tackle optimization issues in both unimodal and multimodal scenarios,and it can give adequate quasi-optimal solutions to these problems.The analysis and comparison of competing algorithms’performance with the proposed algorithm demonstrates the superiority and competitiveness of the AA. | Fatemeh Ahmadi Zeidabadi Mohammad Dehghani Pavel Trojovsky Štěpán Hubálovsky Victor Leiva Gaurav Dhiman | 2022 | Computers, Materials & Continua2022，，7： | 2 |
| 7 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010显示文摘 | Stephen S Lim Theo Vos Abraham D Flaxman Goodarz Danaei Kenji Shibuya Heather Adair-Rohani Mohammad A AlMazroa Markus Amann H Ross Anderson Kathryn G Andrews Martin Aryee Charles Atkinson Loraine J Bacchus Adil N Bahalim Kalpana Balakrishnan John Balmes S | 2012 | The Lancet2012，，9859： | 2 |
| 8 | Relapsing polychondritis: reversible airway obstruction or asthma显示文摘 | Mohammad A Ambrose N Tuohy M | 2008 | Clin Exp Rheumalol2008，26，5： | 1 |
| 9 | Application of a Temperature Dependent Visco- plastic Hierarchical Single Surface Model for Asphalt Mixtures显示文摘 | HUANG B MOHAMMAD L N WATHUGALA G W | 2004 | Journal of Materials in Civil Engineer- ing2004，16，2： | 1 |
| 10 | Combination of super- critical fluid extraction with dispersive liquid liquid microextrac- tion for extraction of organophosphorus pesticides from soil and ma- rine sediment samples 显示文摘 | Mohammad H N Yadollah Y Mohammad R | 2011 | The journal of supercritical fluids2011，57，3： | 1 |
| 11 | Formation of a dense and continuous AI2O3 layer in nano thermal barrier coating systems for the suppression of spinel growth on the AI2O3 oxide scale during oxidation 显示文摘 | DAROONPARVAR M YAJ1D MUHAMAD A M YUSOF N M HUSSAIN MOHAMMAD S RAD HAMID R B | 2013 | Journal of Alloys and Compounds2013，571，： | 1 |
| 12 | Robust and resilientfinite-time bounded control of discrete-time uncertainnonlinear systems 显示文摘 | ElBsat Mohammad N Yaz E E | 2013 | Automatica2013，49，7： | 1 |
| 13 | Vimentin and GFAP responses in astrocytes after contusion trauma to the murine brain显示文摘 | Sara Ekmark-Lewén Anders Lewén Charlotte Israelsson Gui Lin Li Mohammad Farooque Yngve Olsson Ted Ebendal Lars Hillered | 2010 | Restorative Neurology and Neuroscience2010，，3： | 1 |
| 14 | Incidence of up- per limb venous thrombosis associated with peripherally inserted central catheters (PICC) 显示文摘 | Abdullah B J Mohammad N Sangkar JV | 2005 | Br J Radiol2005，78，： | 1 |
| 15 | Nanofiltration of highly concentrated salt solutions up to seawater salinity et al显示文摘 | N Hilal H A1-Zoubi A W Mohammad | 2005 | Desalination2005，184，： | 1 |
| 16 | Treatment of landfill leachate wastewater by nanofihration membrane 显示文摘 | MOHAMMAD A W HILAL N PEI L Y | 2004 | Interna- tional Journal of Green Energy2004，1，2： | 1 |
| 17 | Promoting effl~ct of noble metals addition on activity and resistance to ~'arbon deposition in oxidative steam reforming of methane over NiO-MgO s~lid solu- tion 显示文摘 | Mohammad N Ken-ichiro F Kimihito S | 2006 | Catal Commun2006，7，2： | 1 |
| 18 | Treatment of Landfill Leachate Wastewater by Nanofiltration Membrane显示文摘 | Mohammad A W Hilal N Pei L Y | 2004 | International Journal of Green Energy2004，1，2： | 1 |
| 19 | Tungsten Oxide Nanowires Grown on Carbon Paper as Pt Electrocatalyst Support for High Performance Proton Exchange Memebrane Fuel Cells 显示文摘 | Madhu Sudan Saha Banis Mohammad N Zhang Yong | 2009 | Power Source2009，192，： | 1 |
| 20 | Thermal and catalytic decomposition behavior of PVC mixed plastic waste with petroleum residue显示文摘 | Mohammad F A Mohammad N S | 2005 | Analytical and Applied Pyrolysis2005，74，12： | 1 |
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