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3篇 您的检索式:作者名="Minjun Huang"
    题名 作者 年代 出处 被引量
1A specific aggregation-induced emission-conjugated polymer enables visual monitoring of osteogenic differentiation显示文摘Osteogenic differentiation is the basis of bone growth and repair related to many diseases,in which evaluating the degree and ability of osteogenic transformation is quite important and highly desirable.However,fixing or stopping the growth of cells is required for conventional methods to monitor osteogenic differentiation,which cannot realize the full investigation of the dynamic process.Herein,a new anion conjugated polymer featuring aggregation-induced emission(AIE)characteristics is developed with excellent solubility for in-situ monitoring the process of osteogenic differentiation.This novel polymer can bind with osteogenic differentiated cells,and the intracellular fluorescence increases gradually with the enhancement of osteogenic differentiation.Moreover,it possesses good biosafety with negligible effect on cell activity and osteogenic differentiation,which cannot be realized by the typical method of Alizarin Red S staining.Further study shows that the polymer crosses the cell membrane through endocytosis and enriches in lysosomes,whereas no obvious fluorescence is detected with other cells,including non-differentiated osteoblast cells,under the same conditions,demonstrating the high selectivity.This is the first fluorescent probe with excellent specificity to realize real-time observation of the process of osteogenic differentiation.Therefore,PTB-EDTA shows great promise in the study of osteogenic differentiation and related applications.Zhenyu Zheng Taotao Zhou Rong Hu Minjun Huang Xiang Ao Jun Chu Tao Jiang Anjun Qin Zhongmin Zhang 2020Bioactive Materials2020,5,4:3
2Antimicrobial resistance among clinical isolates from the Chinese Meropenem Surveillance Study (CMSS), 2003–2008显示文摘Hui Wang Minjun Chen Yuxing Ni Yudong Liu Hongli Sun Yunsong Yu Xiujuan Yu Yaning Mei Min Liu Ziyong Sun Yunzhuo Chu Zhidong Hu Xinhong Huang 2009International Journal of Antimicrobial Agents2009,,:1
3The role of RhoA in the migration of endothelial cells stimulated by interleukin-8显示文摘The development and maintenance of an abundant blood supply is essential for the healing of wound and neoplastic tissues.Angiogenesis,the development of new vessels from adjacent capillary networks,plays an important role in physiologic and as well as inMinjun Zou,Xiaoheng Liu,Yi Lai,Ye Zeng,Xianliang Huang(Institute of Biomedical Engineering,West China Center of Medical Sciences,Sichuan University,Chengdu,610041,China 2009医用生物力学2009,24,S1:0
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