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| 1 | Relationship between microvessel density and telomerase activity in hepatocellular carcinoma显示文摘AIM: To study the relationship between microvessel density(MVD), telomerase activity and biological characteristics in hepatocellular carcinoma (HCC).METHODS: S-P immunohistochemical method and telomeric repeat amplification protocol (TRAP) were respectively used to analyze the MVD and telomerase activity in 58 HCC and adjacent normal tissues.RESULTS: The MVD in HCC with metastasis, lower differentiation or without intact capsule was significantly higher than that in HCC with intact capsule, higher differentiation, or without metastasis. While MVD had no relationship with tumor size, hepatic virus infection and other clinical factors. Telomerase activity was related to differentiation degree, but not to tumor size or histological grade. MVD in HCC with telomerase activity was higher than that in HCC without telomerase activity.CONCLUSION: MVD and telomerase activity may serve as diagnostic criteria of HCC in earlier stage. Meanwhile,there may be a cooperative effect between MVD and telomerase on the growth and metastasis of HCC. | Yun-FengPiao MinHe YangShi Tong-YuTang | 2004 | World Journal of Gastroenterology2004，10，14： | 5 |
| 2 | Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network显示文摘The healthcare industry is in dire need of rapid microbial identification techniques for treating microbial infections.Microbial infections are a major healthcare issue worldwide,as these widespread diseases often develop into deadly symptoms.While studies have shown that an early appropriate antibiotic treatment significantly reduces the mortality of an infection,this effective treatment is difficult to practice.The main obstacle to early appropriate antibiotic treatments is the long turnaround time of the routine microbial identification,which includes time-consuming sample growth.Here,we propose a microscopy-based framework that identifies the pathogen from single to few cells.Our framework obtains and exploits the morphology of the limited sample by incorporating three-dimensional quantitative phase imaging and an artificial neural network.We demonstrate the identification of 19 bacterial species that cause bloodstream infections,achieving an accuracy of 82.5%from an individual bacterial cell or cluster.This performance,comparable to that of the gold standard mass spectroscopy under a sufficient amount of sample,underpins the effectiveness of our framework in clinical applications.Furthermore,our accuracy increases with multiple measurements,reaching 99.9%with seven different measurements of cells or clusters.We believe that our framework can serve as a beneficial advisory tool for clinicians during the initial treatment of infections. | Geon Kim Daewoong Ahn Minhee Kang Jinho Park DongHun Ryu YoungJu Jo Jinyeop Song Jea Sung Ryu Gunho Choi Hyun Jung Chung Kyuseok Kim Doo Ryeon Chung In Young Yoo Hee Jae Huh Hyun-seok Min Nam Yong Lee YongKeun Park | 2022 | Light(Science & Applications)2022，11，7： | 2 |
| 3 | Decomposing the influencing factors of industrial carbon emissions in Shanghai using the LMDI method显示文摘 | Min Zhao Lirong Tan Weiguo Zhang Minhe Ji Yuan Liu Lizhong Yu | 2010 | Energy2010，，6： | 2 |
| 4 | Measurement and modeing of PS/Supercritical CO2 solution viscosities 显示文摘 | Minhee Lee Park C B Costas Tzoganakis | 1999 | Polymer Engineering and Science1999，39，1： | 1 |
| 5 | Measurements And Modeling of PS/Supercridcal CO2 Solution Viscosities显示文摘 | Lee Minhee Park Chul B Tzoganakis Costas | 1999 | Polymer Engineering and Science1999，39，1： | 1 |
| 6 | Ckl-Line Measurement of PS/COe Solution Viscosities 显示文摘 | Lee Minhee Park Chul B Tzoganakis Costas | 1997 | Annual Technical Conference - ANTEC Conference Proceedings Materials1997，2，： | 1 |
| 7 | Promoting Students' SelfRegulation Ability Guidelines for Instructional Design 显示文摘 | Minhee Shin | 1998 | Educafional Technology1998，，12： | 1 |
| 8 | 显示文摘 | Minhee Lee Niko G Gubernator | 2010 | J Am Chem Soc2010，132，： | 1 |
| 9 | Application of nonionic surfactant-enhanced in situ flushing to a diesel contaminated site 显示文摘 | Lee Minhee Kang Hyunmin Do Wonhong | 2005 | Water Research2005，39，： | 1 |
| 10 | Endothelial mesenchymal transformation mediated by IL-1β-induced FGF-2 in corneal endothelial cells显示文摘 | Jeong Goo Lee MinHee K. Ko EunDuck P. Kay | 2011 | Experimental Eye Research2011，，1： | 1 |
| 11 | What' s so different about the mobile Internet'? 显示文摘 | Minhee C Jinwoo K | 2003 | Communications of the ACM2003，46，12： | 1 |
| 12 | Isolation and purification of closely related citrus limonoid glucosides by flash chromatography显示文摘 | Girija Raman Minhee Cho Jennifer S Brodbelt | 2005 | Phytochemical Analysis2005，16，3： | 1 |
| 13 | The role of critical shear stress on acute coronary syndrome显示文摘 | F. Jung O.K. Baskurt Jongyoun Kim Hyemoon Chung Minhee Cho Byoung-Kwon Lee Ali Karimi Sehyun Shin | 2013 | Clinical Hemorheology and Microcirculation2013，，1： | 1 |
| 14 | What's so different about the mobile Intemet? 显示文摘 | Minhee Chae Jinwoo Kim | 2003 | Communications of the ACM2003，46，12： | 1 |
| 15 | Sleep disturbances after cerebral infarction: role of depression and fatigue显示文摘 | Suh Minhee Choi-Kwon Kim Jong S | 2014 | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2014，23，7： | 1 |
| 16 | , Remediation of heavy metal contaminated groundwater originated from abandoned mine using lime and calcium carbonate显示文摘 | Minhee Lee In Sung Paik Insu Kim | 2007 | Journal of Hazardous Materials2007，144，12： | 1 |
| 17 | A study of a method for distribution analysis of skin color显示文摘 | Seunghan Ha Minhee Lee | 2009 | Skin Res Technol2009，15，： | 1 |
| 18 | Extrusion of PE/PS Blends with Supercritical Carbon Dioxide 显示文摘 | Minhee Lee Costas Tzoganakis Chul B Park | 1998 | Poly Eng Sci1998，38，7： | 1 |
| 19 | Measurement and Modeling of PS/Supercritical CO2 Solution Viscosities 显示文摘 | Minhee Lee Chul B Park Costas Tzoganakis | 1999 | Poly Eng Sci1999，39，1： | 1 |
| 20 | Decomposing the influencing factors of industrial carbon emissions in Shanghai using the LMDI method显示文摘 | Min Zhao Lirong Tan Weiguo Zhang Minhe Ji Yuan Liu Lizhong Yu | 2010 | Energy2010，，6： | 1 |
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