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| 1 | Tongue coating microbiome as a potential biomarker for gastritis including precancerous cascade显示文摘The development of gastritis is associated with an increased risk of gastric cancer. Current invasive gastritis diagnostic methods are not suitable for monitoring progressIn this work based on 78 gastritis patients and 50 healthy individuals, we observed that the variation of tongue-coating microbiota was associated with the occurrenee and development of gastritis. Twenty-one microbial species were identified for differentiating tongue-coating microbiomes of gastritis and healthy individuals. Pathways such as microbial metabolism in diverse environments, biosynthesis of antibiotics and bacterial chemotaxis were up-regulated in gastritis patients. The abundance of Campylobacter concisus was found associated with the gastric precancerous cascade. Furthermore, Campylobacter concisus could be detected in tongue coating and gastric fluid in a validation cohort containing 38 gastritis patients. These observations provided biological evidence of tongue diagnosis in traditional Chinese medicine, and indicated that tongue-coating microbiome could be a potential non-invasive biomarker, which might be suitable for long-term monitoring of gastritis. | Jiaxing Cui Hongfei Cui Mingran Yang Shiyu Du Junfeng Li Yingxue Li Liyang Liu Xuegong Zhang Shao Li | 2019 | Protein & Cell2019，10，7： | 21 |
| 2 | Engineered three-dimensional scaffolds for enhanced bone regeneration in osteonecrosis显示文摘Osteonecrosis,which is typically induced by trauma,glucocorticoid abuse,or alcoholism,is one of the most severe diseases in clinical orthopedics.Osteonecrosis often leads to joint destruction,and arthroplasty is eventually required.Enhancement of bone regeneration is a critical management strategy employed in osteonecrosis therapy.Bone tissue engineering based on engineered three-dimensional(3D)scaffolds with appropriate architecture and osteoconductive activity,alone or functionalized with bioactive factors,have been developed to enhance bone regeneration in osteonecrosis.In this review,we elaborate on the ideal properties of 3D scaffolds for enhanced bone regeneration in osteonecrosis,including biocompatibility,degradability,porosity,and mechanical performance.In addition,we summarize the development of 3D scaffolds alone or functionalized with bioactive factors for accelerating bone regeneration in osteonecrosis and discuss their prospects for translation to clinical practice. | Tongtong Zhu Yutao Cui Mingran Zhang Duoyi Zhao Guangyao Liu Jianxun Ding | 2020 | Bioactive Materials2020，5，3： | 14 |
| 3 | Study on primal CO gas generation and emission of coal seam显示文摘The main method of casting coal spontaneous combustion is prediction of index gases, with carbon monoxide(CO) commonly used as an index gas. However, coal spontaneous combustion is not the sole source of CO evolution; primal CO is generated through coalification, which can lead to forecasting mistakes. Through theoretical analysis, primal CO generation and emission from coal seams was determined.In this study, six coal samples were analyzed under six different experimental conditions. The results demonstrated the change in coal seam primal gas and concentration as functions of time, different coal samples, occurrence, various gas types and composition concentration, which are in agreement with the previous study on primal CO generation. Air charging impacts on primal gas emission. Analysis of the experimental data with SPSS demonstrates that the relationship between primal CO concentration and time shows a power exponent distribution. | Zhu Hongqing Chang Mingran Wang Haiyan | 2017 | International Journal of Mining Science and Technology2017，27，6： | 7 |
| 4 | 解析胃癌前病变及早期胃癌的单细胞转录组网络显示文摘文章简介本研究采集了一组处于胃癌前病变不同阶段及早期胃癌患者,这些患者还具有胃灼痛、大便干燥、舌苔黄或厚等若干中医'胃火'相关临床表现。通过解析单细胞网络,研究发现高表达MUC6的腺粘膜细胞随着疾病的进展出现了肠样干细胞表型,提示其可能是介导肿瘤发生的关键步骤。 | 张鹏 Mingran Yang Yiding Zhang Shuai Xiao Xinxing Lai Aidi Tan Shiyu Du 李梢 | 2020 | 科学新闻2020，，2： | 7 |
| 5 | M3SC:A Generic Dataset for Mixed Multi-Modal(MMM)Sensing and Communication Integration显示文摘The sixth generation(6G)of mobile communication system is witnessing a new paradigm shift,i.e.,integrated sensing-communication system.A comprehensive dataset is a prerequisite for 6G integrated sensing-communication research.This paper develops a novel simulation dataset,named M3SC,for mixed multi-modal(MMM)sensing-communication integration,and the generation framework of the M3SC dataset is further given.To obtain multimodal sensory data in physical space and communication data in electromagnetic space,we utilize Air-Sim and WaveFarer to collect multi-modal sensory data and exploit Wireless InSite to collect communication data.Furthermore,the in-depth integration and precise alignment of AirSim,WaveFarer,andWireless InSite are achieved.The M3SC dataset covers various weather conditions,multiplex frequency bands,and different times of the day.Currently,the M3SC dataset contains 1500 snapshots,including 80 RGB images,160 depth maps,80 LiDAR point clouds,256 sets of mmWave waveforms with 8 radar point clouds,and 72 channel impulse response(CIR)matrices per snapshot,thus totaling 120,000 RGB images,240,000 depth maps,120,000 LiDAR point clouds,384,000 sets of mmWave waveforms with 12,000 radar point clouds,and 108,000 CIR matrices.The data processing result presents the multi-modal sensory information and communication channel statistical properties.Finally,the MMM sensing-communication application,which can be supported by the M3SC dataset,is discussed. | Xiang Cheng Ziwei Huang Lu Bai Haotian Zhang Mingran Sun Boxun Liu Sijiang Li Jianan Zhang Minson Lee | 2023 | China Communications2023，20，11： | 3 |
| 6 | Biofunctionalized composite scaffold to potentiate osteoconduction,angiogenesis,and favorable metabolic microenvironment for osteonecrosis therapy显示文摘Osteonecrosis is a common orthopedic disease in clinic,resulting in joint collapse if no appropriate treatment is performed in time.Core decompression is a general treatment modality for early osteonecrosis.However,effective bone regeneration in the necrotic area is still a significant challenge.This study developed a biofunctionalized composite scaffold(PLGA/nHA30VEGF)for osteonecrosis therapy through potentiation of osteoconduction,angiogenesis,and a favorable metabolic microenvironment.The composite scaffold had a porosity of 87.7%and compressive strength of 8.9 MPa.PLGA/nHA30VEGF had an average pore size of 227.6μm and a water contact angle of 56.5◦with a sustained release profile of vascular endothelial growth factor(VEGF).After the implantation of PLGA/nHA30VEGF,various osteogenic and angiogenic biomarkers were upregulated by 2-9 fold compared with no treatment.Additionally,the metabolomic and lipidomic profiling studies demonstrated that PLGA/nHA30VEGF effectively regulated the multiple metabolites and more than 20 inordinate metabolic pathways in osteonecrosis.The excellent performances reveal that the biofunctionalized composite scaffold provides an advanced adjuvant therapy modality for osteonecrosis. | Tongtong Zhu Mengyang Jiang Mingran Zhang Liguo Cui Xiaoyu Yang Xukai Wang Guangyao Liu Jianxun Ding Xuesi Chen | 2022 | Bioactive Materials2022，7，3： | 1 |
| 7 | Capn4 contributes to tumor invasion and metastasis in clear cell renal cell carcinoma cells via modulating talin-focal adhesion kinase signaling pathway显示文摘Calpain 小子单元(Capn4 ) 1 被显示了与清楚的房间的转移 / 侵略相关肾的房间癌(ccRCC ) 。这研究试图进一步阐明位于调停 Capn4 的 ccRCC 下面的分子的机制前进。在 ccRCC 房间的 mRNA 表示层次被量的即时 PCR 测量。房间粘附,侵略,和移植上的 Capn4 的效果被房间粘附试金,房间侵略试金,和愈合创伤的试金分别地检验。蛋白质层次被西方的污点分析检测。在 vivo 的癌症转移上的 Capn4 的效果在一个裸体老鼠异种皮移植模特儿被估计。Capn4 在 ccRCC 房间是起来调整的,这被发现,并且 Capn4 overexpression 压制了房间粘附活动并且在 786-O 房间增加了房间侵略和移植,当 Capn4 silencing 增加了房间粘附活动并且损害了侵略和 Caki-1 房间的迁居能力时。Capn4 overexpression 也在 786-O 房间增加了劈开的 talin 的蛋白质水平,当 Capn4 silencing 减少了时在 Caki-1 房间的劈开的 talin 的蛋白质水平。发信号的焦点的粘附 kinase (FAK )/AKT/MAPK 被 Capn4 overexpression 在 786-O 房间激活,并且被 Capn4 下面规定在 Caki-1 房间禁止。Capn4 overexpression 增加了矩阵 metalloproteinase 的蛋白质层次 2 (MMP-2 ) ,在 786-O 房间的 vimentin, N-cadherin,和下面调整的 E-cadherin 当 Capn4 silencing 减少了时,蛋白质在 Caki-1 房间 MMP-2, vimentin, N-cadherin,和起来调整的 E-cadherin 铺平。Capn4 也支持了癌症转移在在里面 vivo 裸体人老鼠异种皮移植模型。我们的结果含有在 ccRCC 侵略和移植的 Capn4 的功能的角色,它可以在 ccRCC 贡献癌症转移。 | Qianfeng Zhuang Weiping Luo Mingran Zhang Min Fan Hao Lu Renfang Xu Xiaozhou He | 2018 | Acta Biochimica et Biophysica Sinica2018，50，5： | 1 |
| 8 | Study on visual assembly process planning system based on 3DVIA composer显示文摘 | CHEN Lei DENG Mingran JIANG Zhengfeng | 2011 | Advanced Materials Research2011，，： | 1 |
| 9 | Degradation behavior of ZE21C magnesium alloy suture anchors and their effect on ligament-bone junction repair显示文摘Current materials comprising suture anchors used to reconstruct ligament-bone junctions still have limitation in biocompatibility,degradability or mechanical properties.Magnesium alloys are potential bone implant materials,and Mg^(2+) has been shown to promote ligament-bone healing.Here,we used Mg-2 wt.%Zn-0.5 wt.%Y-1 wt.%Nd-0.5 wt.%Zr(ZE21C)alloy and Ti6Al4V(TC4)alloy to prepare suture anchors to reconstruct the patellar ligament-tibia in SD rats.We studied the degradation behavior of the ZE21C suture anchor via in vitro and in vivo experiments and assessed its reparative effect on the ligament-bone junction.In vitro,the ZE21C suture anchor degraded gradually,and calcium and phosphorus products accumulated on its surface during degradation.In vivo,the ZE21C suture anchor could maintain its mechanical integrity within 12 weeks of implantation in rats.The tail of the ZE21C suture anchor in high stress concentration degraded rapidly during the early implantation stage(0-4weeks),while bone healing accelerated the degradation of the anchor head in the late implantation stage(4-12weeks).Radiological,histological,and biomechanical assays indicated that the ZE21C suture anchor promoted bone healing above the suture anchor and fibrocartilaginous interface regeneration in the ligament-bone junction,leading to better biomechanical strength than the TC4 group.Hence,this study provides a basis for further research on the clinical application of degradable magnesium alloy suture anchors. | Delin Ma Jun Wang Mingran Zheng Yuan Zhang Junfei Huang Wenxiang Li Yiwen Ding Yunhao Zhang Shijie Zhu Liguo Wang Xiaochao Wu Shaokang Guan | 2023 | Bioactive Materials2023，，8： | 1 |
| 10 | Flat soliton microcomb source显示文摘Mode-locked microcombs with flat spectral profiles provide the high signal-to-noise ratio and are in high demand for wavelength division multiplexing(WDM)-based applications,particularly in future high-capacity communication and parallel optical computing.Here,we present two solutions to generate local relatively flat spectral profiles.One microcavity with ultra-flat integrated dispersion is pumped to generate one relatively flat single soliton source spanning over 150 nm.Besides,one extraordinary soliton crystal with single vacancy demonstrates the local relatively flat microcomb lines when the inner soliton spacings are slightly irregular.Our work paves a new way for soliton-based applications owing to the relatively flat spectral characteristics. | Xinyu Wang Xuke Qiu Mulong Liu Feng Liu Mengmeng Li Linpei Xue Bohan Chen Mingran Zhang Peng Xie | 2023 | Opto-Electronic Science2023，2，12： | 1 |
| 11 | Tlx1/3 and Ptf1a Control the Expression of Distinct Sets of Transmitter and Peptide Receptor Genes in the Developing Dorsal Spinal Cord显示文摘 | Zhen Guo Congling Zhao Menggui Huang Tianwen Huang Mingran Fan Zhiqin Xie Ying Chen Xiaolin Zhao Guannan Xia Junlan Geng Leping Cheng | 2012 | Journal of Neuroscience2012，，： | 1 |
| 12 | The Problem of Confucian Moral Cultivation and Its Solution: Using Ritual Propriety to Support Rule by Law显示文摘在改革以后的中国考虑道德的衰落,作者基于道德的教育分析善良的统治的发展,并且断定古老的统治者那么与它被变得昏头昏脑的原因是在熟悉的邻居的道德的违反上的公共评估的禁止的功能。然而,当中国转变成一个动态、商业的社会,和它的人,从熟悉的邻居搬到城市到离间的社区,公共评估在道德的犯规者上正在失去它的力量。阻止道德的系统的倒塌,由法律使用统治促进公正和 rule-consciousnessnot 的民族感觉简单地希望更多的利他主义者的外观是必要的。因为法律是道德的原则的化身,这是可能的,并且因为法律抑制和惩罚能作为习惯被使内在化。在公正和规则知觉的一种感觉在人被建立了以后,我们能再收起儒家优点教育养育民族羞耻感和尊严,和他们的仁慈、正直的头脑。然而,停止当前的混乱和贪污,我们由法律采用统治并且与道德的教育补充它,是迫切的。 | TAN Mingran | 2016 | Frontiers of Philosophy in China2016，11，1： | 0 |
| 13 | Wang Fuzhrs Interpretation of Spirit/Shenin His AnnotaUon on the Zhuangzi显示文摘这篇散文系统地在 Zhuangzi (Zhuangzi Jie ) 上在王 Fuzhis 注解探索概念精神(shen ) 。后面的 Zhuangzi,王福志作为人的生活和人的身体的主人作为重要 force/jingqi,和问候精神的一个团解释精神。通过保存精神,一个愿望不仅能保存身体,而且从疾病和瘟疫使所有动物有免疫力。这能被完成,自从保存得很好的精神将贡献和谐、纯的 qi 到宇宙并且使整个宇宙更和谐。以达到这个目的,王福志求婚忘记所有外部事情并且一方面,为空、分开的头脑瞄准并且要求一个人与一个经常的愿望集中他的精神,一只另外的手。一次精神很好被集中,一个人将是一个精神的人(shenren ) 将超越生活和死亡,运气和不幸,总是过从容、无忧无虑的生活。一个人将也忘记所有认知区别并且充分与事情和天堂(tian ) 的转变成为一个。这样,精神将完成永恒,并且充分认识到人的生活的意思。 | TAN Mingran | 2015 | Frontiers of Philosophy in China2015，10，2： | 0 |
| 14 | Programmable microfluidics for dynamic multiband camouflage显示文摘Achieving multiband camouflage covering both visible and infrared regions is challenging due to the broad bandwidth and differentiated regulation demand in diverse regions.In this work,we propose a programmable microfluidic strategy that uses dye molecules in layered fluids to manipulate visible light-and infrared-semitransparent solvent to manipulate infrared light.With three primary fluid inputs,we achieve 64 chromaticity values and 8 emissivities from 0.42 to 0.90.In view of the wide tuning range,we demonstrate that the microfluidic flm can dynamically change its surface reflectance to blend into varying backgrounds in both visible and infrared images.Moreover,we fabricate the microfluidic device in a textile form and demonstrate its ability to match exactly with the colors of natural leaves of different seasons in the full hyperspectrum range.Considering the broadband modulation and ease of operation,the programmable microfluidic strategy provides a feasible approach for smart optical surfaces in long-span optical spectra. | Chunzao Feng Mingran Mao Xiaohui Zhang Yutian Liao Xiaohui Xiao Huidong Liu Kang Liu | 2023 | Microsystems & Nanoengineering2023，9，2： | 0 |
| 15 | A Neo-Confucian Criticism of Daoism:Wang Fuzhi's Contradictory Remarks on the Laozi显示文摘Based on Zhu Xi's statement that Laozi's teachings were very cruel,Wang Fuzhi condemned Laozi as a crafty,petty person in his Confucian commentaries.Yet,he had to understand the Laozi or Daodejing sympathetically when he commented on it in Laozi Yan老子衍(Extended Commentary on the Laozi).As a result,he showed inconsistency in his criticism and evaluation of the author.Some scholars have noted this problem but have not shed ink analyzing it.This essay finds that Wang Fuzhi's ambiguous attitude toward Laozi results from his Confucian prejudice against other schools and his failure to grasp the breadth and depth of Laozi's thought.From the perspective of Heaven,Laozi promoted accommodation and non-interference in self-cultivation and governance,summed up by the maxim that'the sage manages affairs without deliberation,and spreads teachings without words.'In contrast,Wang Fuzhi stuck to the distinction between Confucianism and Daoism,and tried to use humanity and ritual propriety to supplement that which Heaven does not provide;as such,he criticized Laozi as crafty and irresponsible.Wang Fuzhi's criticism neither hits the mark regarding Laozi's weakness nor maintains a concordance with his earlier sympathetic appraisal in Laozi Yan;the reason for this is that Wang Fuzhi could not fully grasp Laozi's thought from a Confucian and anthropocentric perspective. | TAN Mingran | 2020 | Frontiers of Philosophy in China2020，15，1： | 0 |
| 16 | Research on Measures to Improve the Flexibility of Enterprise Finance System显示文摘 | Mingran Deng Ming Fang | 2003 | Chinese Business Review2003，2，3： | 0 |
| 17 | A Study on USA Promoting the Development of Middle and Small-sized Enterprises and Its Revelation显示文摘 | Shuping Zhang Mingran Deng | 2005 | Chinese Business Review2005，4，7： | 0 |
| 18 | Broadband light management in hydrogel glass for energy efficient windows显示文摘Windows are critically important components in building envelopes that have a signifcant efect on the integral energy budget.For energy saving,here we propose a novel design of hydrogel-glass which consists of a layer of hydrogel and a layer of normal glass.Compared with traditional glass,the hydrogel-glass possesses a higher level of visible light transmission,stronger near-infrared light blocking,and higher mid-infrared thermal emittance.With these properties,hydrogel-glass based windows can enhance indoor illumination and reduce the temperature,reducing energy use for both lighting and cooling.Energy savings ranging from 2.37 to 10.45 MJ/m2 per year can be achieved for typical school buildings located in diferent cities around the world according to our simulations.With broadband light management covering the visible and thermal infrared regions of the spectrum,hydrogel-glass shows great potential for application in energy-saving windows. | Jia Fu Chunzao Feng Yutian Liao Mingran Mao Huidong Liu Kang Liu | 2022 | Frontiers of Optoelectronics2022，15，3： | 0 |
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