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| 1 | Impact of the Three Gorges Project operation on the water exchange between Dongting Lake and the Yangtze River显示文摘The Three Gorges Project(TGP) is a world known project to utilize and manage the water resources of the Yangtze River. The reservoir stores water at the end of the flood season, and replenishes downstream reaches with water in dry seasons. In addition to such benefits, the TGP has irreversibly changed the hydrological process and the river-lake relation of the middle and lower reaches. In this paper, a hydrodynamic model was established to quantify the impact of the TGP's operation on the water exchange between Dongting Lake and the Yangtze River during 2009-2013. The results indicated that:the operation of the TGP has considerably reduced the peak discharge and the flood volume of the main stream and the Dongting Lake area. The inflow volume from the Yangtze River to Dongting Lake via three outlets decreased by 1.9-3.5 billion m^3/yr, while the outflow volume from Dongting Lake to the Yangtze River at Chenglingji increased by 0.3-1.6 billion m^3 in September and 0.4-0.6 billion m^3 in October,respectively. This research provides valuable information for flood control, irrigation, and water allocation in the middle and lower reaches of the Yangtze River, and serves as a typical case for investigating the impact of other hydropower projects around the world. | Minglong Dai Jun Wang Mingbo Zhang Xi Chen | 2017 | International Journal of Sediment Research2017，32，4： | 14 |
| 2 | Hot deformation behavior of Mg-7.22Gd-4.84Y-1.26Nd-0.58Zr magnesium alloy显示文摘The behavior evolvement of Mg-7.22Gd-4.84Y-1.26Nd-0.58Zr(GWN751K) magnesium alloy during the hot deformation process was discussed.The flow stress behavior of the magnesium alloy over the strain rate range of 0.002 to 2.000 s-1 and in the temperature range of 623 to 773 K was studied on a Gleeble-1500D hot simulator under the maximum deformation degree of 60%.The experimental results showed that the relationship between stress and strain was obviously affected by strain rate and deformation temperature.The flow stress of GWN751K magnesium alloy during high temperature deformation could be represented by the Zener-Hollomon parameter in the hyperbolic Arrhenius-type equation.The stress exponent n and deformation activation energy Q were evaluated by linear regression analysis.The stress exponent n was fitted to be 3.16.The hot deformation activation energy of the alloy during hot deformation was 230.03 kJ/mol.The microstructures of hot deformation were also influenced by strain rate and compression temperature strongly.It was found that the alloy could be extruded at 723 K with the mechanical properties of σ0.2 = 260 MPa,σb = 320 MPa,and δ = 18%. | ZHANG Kui MA Minglong LI Xinggang LI Yongjun LIANG Lichao BING Mengfen | 2011 | Rare Metals2011，30，1： | 13 |
| 3 | Microstructural evolution and mechanical properties of Mg-5Y-5Gd-xNd-0.5Zr magnesium alloys at different states显示文摘The microstructural evolution and mechanical properties of Mg-5Y-5Gd-xNd-0.5Zr magnesium alloys at different states were studied.The results reveal that island compounds at the grain boundaries of the as-cast alloys mainly were Mg24Y5,Mg41Nd5,and Mg5Gd phases.After homogenization at 808 K for 24 h,the distribution of the island compounds became discrete and Mg5Gd phases mostly decomposed and dissolved.With hot extrusion,the grain size was refined to about 20 μm on average,and both the strength and elongation were greatly improved.After ageing at 523 K for 5 h,the strength of different extruded alloys largely increased but the elongation decreased.With the increase of neodymium content,the strength of the alloys at different states increased.The content of neodymium element had an obvious effect on the elongation of the designed alloys.In the designed alloys,the Mg-5Y-5Gd-2.2Nd-0.5Zr alloy exhibited the best combination properties and its ultimate tensile strength,yield strength,and elongation could reach 380 MPa,285 MPa,and 9.0%,respectively. | LI Yongjun ZHANG Kui ZHANG Ya LI Xinggang MA Minglong | 2010 | Rare Metals2010，29，3： | 11 |
| 4 | Ventricular tachycardia ablation and substrate modification in ICD patients with electrical storm显示文摘The electrical storm(ES) is defined as a state of electrical instability with three or more sustained ventricular arrhythmias(VAs) occurring within twenty-four hours,which needs intravenous antiarrhythmic medications and frequent defibrillation.Recently,radiofrequency catheter ablation evolved as a sole therapy to terminate ES in patients with ICD,and the survival has been reported to be improved with successful ablation during follow-up.In this review,we briefly summarize substrate mapping and substrate ablation strategy in patients with ES,and discuss the reason of recurrence after ablation. | Minglong Chen | 2015 | The Journal of Biomedical Research2015，29，1： | 10 |
| 5 | Constitutive modeling of flow behavior and processing maps of Mg-8.1 Gd-4.5Y-0.3Zr alloy显示文摘High temperature deformation behavior and workability of Mg-8.1 Gd-4.5Y-0.3Zr alloy were studied by compression tests.Arrhenius equation with strain compensation and processing maps were established.The results show that the activation energy Q,structure factor a,n and In A varies with the strain,its relationship fit well by fifth order polynomial.The flow stresses predicted by the extracted model are in good agreement with the experimental results.There are five typical domains in the processing map,and the deformation mechanisms in different domains were determined by microstructure analysis.The feasible processing window of the alloy is in the areas of 400-500℃/0.001-0.1 s^(-1). | Xiangsheng Xia Kui Zhang Minglong Ma Ting Li | 2020 | Journal of Magnesium and Alloys2020，8，3： | 9 |
| 6 | Corrosion behavior of Mg-Y alloy in NaCl aqueous solution | Xin Zhang a,b,c,Kui Zhang a,Xia Deng a,Hongwei Li b,c,Yongjun Li a,Minglong Ma a,Ning Li b,c,Yanlong Wang b,c a State Key Laboratory for Fabrication and Processing of Nonferrous Metals,Beijing General Research Institute for Nonferrous Metals,Beijing 100088,China b Beijing Engineering Research Center for Advanced Manufacturing and Evaluation of Special Vehicle Parts,Beijing 100072,China c Center of Technology,Beijing North Vehicle Group Corporation,Beijing 100072,China | 2012 | Progress in Natural Science:Materials International2012，22，2： | 7 |
| 7 | Predictors of post coronary artery bypass grafting atrial fibrillation显示文摘Objective: To investigate the incidence and relative risk factors of post coronary artery bypass grafting(post-CABG) atrial fibrillation(AF). Methods: 312 patients with CABG were reviewed and divided into an AF group and a non-AF group. Statistical analysis was used to compare the data between the two groups and screen for risk factors of post-CABG AF. Results: 103/312 (33.01%) patients developed post-CABG AF. Univariate analysis showed that patients in AF group compared with those in non-AF group were more likely to have advanced age (≥70 years), early postoperative withdrawal of β-blockers, hypertension, left atrial enlargement (≥40 mm), a history of AF, prolonged p-wave duration (≥120 ms) and increased number of grafts (≥3). Multivariate logistic regression analysis showed that advanced age (≥70 years), early postoperative withdrawal of β-blockers, hypertension, left atrial enlargement (≥40 mm) and a history of AF were highly related to post-CABG AF. Conclusion: The incidence of AF in patients following CABG was 33.01% in this study. Advanced age, early postoperative withdrawal of β-blockers, hypertension, left atrial enlargement and a history of AF were independent risk factors of post-CABG AF. | Tongtong Shen Qijun Shan Biao Yuan Bing Yang Chun Chen Dongjie Xu Minglong Chen Jiangang Zou Kejiang Cao | 2007 | Journal of Nanjing Medical University2007，21，3： | 5 |
| 8 | Microstructures and strengthening mechanisms of Mg-8.2Gd-4.6Y-1.5Zn-0.4Zr alloy containing LPSO,β’ and γ type phases显示文摘The microstructures and strengthening mechanisms of the Mg-8.2 Gd-4.6 Y-1.5 Zn-0.4 Zr(wt%) alloy with long-period stacking ordered(LPSO),β’ and γ type phases were systematically studied.The results show that the LPSO with lamellar and block structures forms near the grain boundaries.The grains are clearly refined,and the 18 R LPSO phase is oriented along the extrusion direction after extrusion.Some particles also precipitate from the Mg matrix dynamically.The extruded alloy exhibits a remarkable agehardening response,and mechanical properties,with a tensile strength(TS) of 449 MPa,yield strength(YS) of 362 MPa,and elongation of 7.9% obtained in the peak-aged alloy.The strengthening mechanisms of the alloy in different states are discussed.Grain boundary and precipitation strengthening are the main strengthening mechanisms for the peak-aged alloy. | Xiangsheng Xia Kui Zhang Minglong Ma Ting Lie | 2020 | Journal of Rare Earths2020，38，10： | 5 |
| 9 | miR-23b promotes cutaneous wound healing through inhibition of the inflammatory responses by targeting ASK1显示文摘Wound healing is a complicated event that develops in three overlapping phases:inflammatory, proliferative,and remodeling.MicroRNAs (miRNAs)have been proved to play an important role in the healing process of skin trauma,and alteration of specific miRNA expression during different phases may be associated with abnormal wound healing.In this study,we determined the variation of miR-23b expression after trauma in normal mice and in cultured cells exposed to lipopolysaccharide.We further demonstrated that excessive miR-23b could significantly accelerate wound healing in vivo.Up-regulation of miR-23b decreases infiltration of inflammatory cells,as evidenced by pathologic staining.Meanwhile,miR-23b could significantly inhibit the expression of pro-inflammatory cytokines,including TNF-α,IL-1β,IL-6,and Ccl2,and significantly increase antiinflammatory factor IL-10.Furthermore,miR-23b could also promote α-SMA expression in a fiber pattern and increase the expression of Col1a1 and Col3a1.Importantly,we also showed that miR- 23b could inhibit inflammation to promote wound healing by targeting apoptotic signal-regulating kinase 1 (ASK1).Notably,knockdown of ASK1 could reduce inflammation factor expression in vitro.Together,our data reveal that miR-23b is a potent therapeutic agent for cutaneous wound healing that shortens the period of inflammatory responses and promotes keratinocyte migration for the re-epithelialization of wound sites. | Hongzhi Li Xiao Han Kuiyang Zuo Li Li Jieting Liu Xiaohuan Yuan Yongchao Shen Minglong Shao Daxin Pang Yanhui Chu Binghai Zhao | 2018 | Acta Biochimica et Biophysica Sinica2018，50，11： | 5 |
| 10 | Thermal Growth and Nanomagnetism of the Quasi-one Dimensional Iron Oxide显示文摘Quasi-one dimensional iron oxide nanowires with flat needle shape were synthesized on the iron powders by a rather simple catalyst-free thermal oxidation process in ambient atmosphere. The characterization by field emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Raman and high-resolution transmission electron microscopy (HRTEM) revealed that these nanostructures are single crystalline α-Fe2O3. The various dimensions with 40-170 nm in width and 1-8 μm in length were obtained by tuning the growth temperature from 280 to 480℃. A surface diffusion mechanism was proposed to account for the growth of quasi-one dimensional nanostructure. The typical α-Fe2O3 nanowires synthesized at 430℃ had a reduced Morin temperature TM of 131 K in comparison with their bulk counterpart. The coercivitis Hc of these nanowires are 321 and 65 Oe at 5 and 300 K, respectively. The temperature of synthesis also has important effects on the magnetic properties of these nanowires. | Minglong Zhong Zhongwu Liu Xichun Zhong Hongya Yu Dechang Zeng | 2011 | Journal of Materials Science & Technology2011，27，11： | 5 |
| 11 | Anisotropy of the crystallographic orientation and corrosion performance of high-strength AZ80 Mg alloy显示文摘A high-strength AZ80 Mg alloy was prepared through multi-direction forging,thermal extrusion,and peak-aged heat treatment.The microstructure,crystallographic orientation and corrosion performance of extrusion-direction,transverse-direction,and normal-direction specimens were investigated using scanning electron microscopy,electron backscatter diffraction,and atomic force microscopy,respectively.Experimental results showed that crystallographic orientation significantly influenced the corrosion performance of AZ80 Mg alloy.Corrosion rates largely increased with decreased(0001)crystallographic plane intensity,whereas the(10−10)and(2−1−10)crystallographic plane intensities increased.This study showed that the corrosion rates of alloy can be modified to some extent by controlling texture,thereby promoting the applications of high-strength AZ80 Mg alloys in the aerospace and national-defense fields. | Quantong Jiang Xiumin Ma Kui Zhang Yantao Li Xinggang Li Yongjun Li Minglong Ma Baorong Hou | 2015 | Journal of Magnesium and Alloys2015，3，4： | 5 |
| 12 | Relationship between extrusion,Y and corrosion behavior of MgeY alloy in NaCl aqueous solution显示文摘The effect of hot extrusion and addition of Y element on the corrosion behavior of MgeY alloy was investigated by weight loss,immersion tests and potentiodynamic polarization measurements.The results showed that the grains became finer and uniform by increasing Y element,after extrusion.The corrosion resistance of MgeY alloy after extrusion was deteriorated with the addition of Y element and corrosion rates decreased in the following order:Mge13.78Y>Mge7.46Y>Mge5.23Y. | Kui Zhang Xin Zhang Xia Deng Xinggang Li Minglong Ma | 2013 | Journal of Magnesium and Alloys2013，1，2： | 4 |
| 13 | Effect of burden and origin sites of premature ventricular contractions on left ventricular function by 7-day Holter monitor显示文摘Recent studies have shown that premature ventricular contractions(PVCs) could enlarge the heart,but its risk factors are incompletely understood as a single 24-hour recording cannot reflect the true PVC burden due to day-to-day variability.Our purpose was to investigate the effect of burden and origin sites on left ventricular(LV) function in patients with PVCs by 7-day Holter electrocardiography(ECG).From May 2012 to August2013,112 consecutive patients with PVCs were recruited from the authors' affiliated hospital.All patients received2-dimensional transthoracic echocardiography,12-lead routing ECG and 7-days Holter ECG.Serum N-terminal probrain natriuretic peptide(NT-proBNP) levels were measured.A total of 102 participants with PVCs were included in the final analysis.Origin of PVCs from the tricuspid annulus had the highest burden and NT-proBNP level.LV papillary muscle had a higher LV ejection fraction(EF) level and a lower LV end-systolic dimension(ESD) than other PVC foci(P<0.05).The high burden group had a higher LV end-diastolic dimension(EDD) and LVESD but lower LVEF than the other two groups(P<0.05).Female,older age,physical work,and history of PVCs had a significantly positive correlation with symptoms.Male,older age,physical work,and high burden were positive predictors of enlarged LVEDD,LVESD and higher serum NT-proBNP level,but lower LVEF.Seven-day dynamic ECG Holter monitor showed the true PVC burden on patients with PVCs.PVCs with a lower burden or origin from the LV papillary muscle and the fascicle were relatively benign,while PVCs with a higher burden or origin from the tricuspid annulus may lead to cardiac dysfunction. | Wenhua Xu Mingfang Li Minglong Chen Bing Yang Daowu Wang Xiangqing Kong Hongwu Chen Weizhu Ju Kai Gu Kejiang Cao Hailei Liu Qi Jiang Jiaojiao Shi Yan Cui Hong Wang | 2015 | The Journal of Biomedical Research2015，29，6： | 4 |
| 14 | Genetics of psoriasis:a basis for precision medicine显示文摘Psoriasis is an inflammatory skin disease with a background of polygenic inheritance.Both environmental and genetic factors are involved in the etiology of the disease.In the last two decades,numerous studies have been conducted through linkage analysis,genome-wide association study(GWAS),and direct sequencing to explore the role of genetic variation in disease pathogenesis and progression.To date,>80 psoriasis susceptibility genes have been identified,including HLA-Cw6,IL12B,IL23R,and LCE3B/3C.Some genetic markers have been applied in disease prediction,clinical diagnosis,treatment,and new drug development,which could further explain the pathogenesis of psoriasis and promote the development of precision medicine.This review summarizes related research on genetic variation in psoriasis and explores implications of the findings in clinical application and the promotion of a personalized medicine project. | Delin Ran Minglong Cai Xuejun Zhang | 2019 | Precision Clinical Medicine2019，2，2： | 4 |
| 15 | A novel oncolytic virus engineered with PD-L1 scFv effectively inhibits tumor growth in a mouse model显示文摘The adoptive transfer of engineered chimeric antigen receptor(CAR)T cells has yielded impressive clinical results for targeting hematological cancers.1 However,the advancement of CAR T-cell therapy in solid tumors remains limited,due to the scarcity of tumor antigens that are deemed safe for targeting.Moreover,the requirement of patient-specific autologous T cells for the current standard treatment has also hampered its application.Oncolytic virus(OV)therapy has been classified as another form of novel immunotherapy. | Chuanjian Wu Manman Wu Minglong Liang Sidong Xiong Chunsheng Dong | 2019 | Cellular & Molecular Immunology2019，16，9： | 3 |
| 16 | Ni/Pd-based ohmic contacts to p-GaN through p-InGaN/p^(+)-GaN contacting layers显示文摘Specific contact resistance to p-GaN was measured for various structures of Ni/Pd-based metals and thin(20-30 nm thick)p-InGaN/p^(+)-GaN contacting layers.The effects of surface chemical treatment and annealing temperature were ex-amined.The optimal annealing temperature was determined to be 550°C,above which the sheet resistance of the samples de-graded considerably,suggesting that undesirable alloying had occurred.Pd-containing metal showed~35%lower com-pared to that of single Ni.Very thin(2-3.5 nm thick)p-InGaN contacting layers grown on 20-25 nm thick p^(+)-GaN layers exhib-ited one to two orders of magnitude smaller values of compared to that of p^(+)-GaN without p-InGaN.The current density de-pendence of,which is indicative of nonlinearity in current-voltage relation,was also examined.The lowest achieved through this study was 4.9×10^(-5)Ω·cm^(2)@J=3.4 kA/cm^(2). | Minglong Zhang Masao Ikeda Siyi Huang Jianping Liu Jianjun Zhu Shuming Zhang Hui Yang | 2022 | Journal of Semiconductors2022，43，9： | 3 |
| 17 | Methylesterification of cell-wall pectin controls the diurnal flower-opening times in rice显示文摘Flowers are the core reproductive organ of plants, and flowering is essential for cross-pollination. Diurnal flower-opening time is thus a key trait influencing reproductive isolation, hybrid breeding, and thermostability in plants. However, the molecular mechanisms controlling this trait remain unknown. Here, we report that rice Diurnal Flower Opening Time 1 (DFOT1) modulates pectin methylesterase (PME) activity to regulate pectin methylesterification levels of the lodicule cell walls, which affect lodicule swelling to control diurnal flower-opening time. DFOT1 is specifically expressed in the lodicules, and its expression gradually increases with the approach to flowering but decreases with flowering. Importantly, a knockout of DFOT1 showed earlier diurnal flower opening. We demonstrate that DFOT1 interacts directly with multiple PMEs to promote their activity. Knockout of PME40 also resulted in early diurnal flower opening, whereas overexpression of PME42 delayed diurnal flower opening. Lower PME activity was observed to be associated with higher levels of pectin methylesterification and the softening of cell walls in lodicules, which contribute to the absorption of water by lodicules and cause them to swell, thus promoting early diurnal flower opening. Higher PME activity had the opposite effect. Collectively, our work uncovers a molecular mechanism underlying the regulation of diurnal flower-opening time in rice, which would help reduce the costs of hybrid breeding and improve the heat tolerance of flowering plants by avoiding higher temperatures at anthesis. | Mumei Wang Xiaopei Zhu Guoqing Peng Minglong Liu Shuqing Zhang Minghao Chen Shitang Liao Xiaoying Wei Peng Xu Xiyu Tan Fangping Li Zhichuan Li Li Deng Ziliang Luo Liya Zhu Shuai Zhao Dagang Jiang Jing Li Zhenlan Liu Xianrong Xie Shaokui Wang Aimin Wu Chuxiong Zhuang Hai Zhou | 2022 | Molecular Plant2022，15，6： | 2 |
| 18 | Tpeak-Tend interval as a new risk factor for arrhythmic event in pa-tient with Brugada syndrome显示文摘Objective: To evaluate Tpeak- Tend ( Tp- e) interval in surface standard ECG as a new risk factor for arrhythmic event inpatient with Brugada syndrome. Methods: 23 male patients with Brugada syndrome and 20 male patients with paroxysmalsupraventricular tachycardia ( PSVT) as the control group were investigated in this study. Tp- e interval in surface standardECG was compared between BrS and PSVT patients. Results: Tp- e interval in BrS patients was significantly longer thanthat in PSVT patients ( 109.57±22.86 ms vs. 88.50±13.08ms, P<0.05) . There was significant difference in Tp- e interval be-tween 16 BrS patients with arrhythmic events ( including syncope, clinical ventricular fibrillation [ VF] and programmed elec-trical stimulation [ PES] - induced VF) and 7 BrS patients without arrhythmic events and PSVT patients ( 118.12±20.40ms vs.90.00±15.27ms, P<0.05; 118.12±20.40ms vs. 88.50±13.08ms, P<0.05). However, Tp- e interval was similar in BrS patients with-out arrhythmic events and PSVT patients (90.00±15.27ms vs 88.50±13.08ms, P>0.05). Conclusion: The prolongation of Tp- einterval could serve as a new noninvasive event predictor for arrhythmic events in patients with Brugada syndrome. | Jinfeng Wang Qijun Shan Bing Yang Minglong Chen Jiangang Zou Dongjie Xu Chun Chen Kejiang Cao | 2007 | Journal of Nanjing Medical University2007，21，4： | 2 |
| 19 | ALLIANCE-ROS:A Software Framework on ROS for Fault-Tolerant and Cooperative Mobile Robots显示文摘Programming control systems for mobile robots is complicated and time-consuming, due to three aspects, i.e., the robot behavior coordination, the distributed multi-robot cooperation and the robot software reusability. Subsumption model is a robust control architecture for mobile robots. ALLIANCE model extends it to multirobot systems, which is a fully distributed, fault-tolerant model. Robot operating system(ROS) provides a lot of reusable robot modules. By combining the above three, we propose a software framework named ALLIANCE-ROS for developing fault-tolerant cooperative multi-robot systems with abundant software resources available. We encapsulate the ROS facilities to build the framework prototype.We also use some high-performance plugin-based mechanism to optimize the bottom of the framework. One may use the framework-provided API conveniently to construct single-robot and multi-robot applications with all ROS resources available. This work is demonstrated by three application cases including an autonomous roving robot, a security patrol robot and multiple patrol robots. They are constructed and tested in both the simulated and the real environment. The experimental results validate the usability and availability of ALLIANCE-ROS. | GUO Zhongyuan YANG Wenjing LI Minglong YI Xiaodong CAI Zhongxuan WANG Yanzhen | 2018 | Chinese Journal of Electronics2018，27，3： | 2 |
| 20 | Assessment of atrial electromechanical interval using echocardiography after catheter ablation in patients with persistent atrial fibrillation显示文摘We sought to investigate variation of atrial electromechanical interval after catheter ablation procedure in patients with persistent atrial fibrillation using pulse Doppler(PW) and pulse tissue Doppler imaging(PW-TDI).A total of 25 consecutive in-patients with persistent atrial fibrillation,who restored sinus rhythm after ablation procedure,were recruited in our cardiac center.Echocardiography was performed on each patient at 2 hours,1 day,5 days,1 month and 3 months after the ablation therapy,and atrial electromechanical delay was measured simultaneously by PW and PW-TDI.There was no significant difference between PW and TDI in measuring atrial electromechanical delay.However,at postoperative 2 hours,peak A detection rates were mathematically but nonsignificantly greater by PWTDI than by PW.Second,there was a significant decreasing trend in atrial electromechanical interval from postoperative 2 hours to 3 months,but only postoperative 2-hour atrial electromechanical interval was significantly greater than atrial electromechanical interval at other time.Lastly,patients without postoperative 2-hour atrial electromechanical interval had a significantly longer duration of atrial fibrillation as compared to those with postoperative 2-hour atrial electromechanical interval,by the PW or by PW-TDI,respectively.In patients with persistent atrial fibrillation,atrial electromechanical interval may decrease significantly within the first 24 hours after ablation but remain consistent later,and was significantly related to patients' duration of atrial fibrillation.Atrial electromechanical interval,as a potential predicted factor,is recommended to be measured by either PW or TDI after24 hours,when patients had recovered sinus rhythm by radiofrequency ablation. | Xiaodong Chen Minglong Chen Yingying Wang Bing Yang Weizhu Ju Fengxiang Zhang Kejiang Cao | 2016 | The Journal of Biomedical Research2016，30，6： | 2 |
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