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| 1 | Bromodeoxyuridine promotes full-chemical induction of mouse pluripotent stem cells显示文摘 | YuanLong, MinWang, HaifengGu and XinXie | 2015 | Cell Research2015，25，10： | 13 |
| 2 | Correlation between metastatic potential and variants from colorectal tumor cell line HT-29显示文摘AIM: To evaluate the relationship between uPA, PAI-1,CEA, PI3K and metastatic potential in three colorectal tumor cell lines.METHODS: Metastatic model in nude rats was established by variants HT-29c and HT-29d cell lines and the metastatic potential of two tumor cell variants was compared.Urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) were determined using ELISA in colorectal carcinoma WiDr, HT29 and HT-29d cell lines with different metastatic potentials.Expression of carcinoembryonic antigen (CEA) and phosphoinositide 3-kinase (PI3-Kinase) was analyzed using immunohistochemistry (IHC) in these cell lines in vitro and in vivo. CEA expression was compared using fluorescence activated cell sorter (FACS)in vitro.RESULTS: The number of HT-29d cells arrested in liver dramatically decreased within the initial 24 hours after injection. The taking rate of liver metastases in the variant HT-29d increased as compared with parental HT-29 cells (70 % versus 50 %) and a variant HT-29b cells (70 % versus 60 %), and extensive organs were synchronously involved in metastases. The uPA concentration of variant HT-29d cell line was significantly higher than that of the non-metastatic WiDr and the low metastatic HT-29 cell lines. The variant HT-29d cells produced stronger PI3-kinase expression as compared with the non-metastatic WiDr cells and the low metastatic HT-29 cellsin vivo.CONCLUSION: The selected variant HT-29d cell exhibited an enhanced metastatic potential. The level of uPA and PAI-1 is positively correlated with the metastatic capacity of tumor cells. The expression of PI3-kinase correlates with tumor development and metastasis. | MinWang IlkaVogel HolgerKalthoff | 2003 | World Journal of Gastroenterology2003，9，11： | 8 |
| 3 | Standard pancreatoduodenectomy versus extended pancreatoduodenectomy with modified retroperitoneal nerve resection in patients with pancreatic head cancer:a multicenter randomized controlled trial显示文摘Background:The extent of pancreatoduodenectomy for pancreatic head cancer remains controversial,and more high-level clinical evidence is needed.This study aimed to evaluate the outcome of extended pancreatoduodenectomy(EPD)with retroperitoneal nerve resection in pancreatic head cancer.Methods:This multicenter randomized trial was performed at 6 Chinese highvolume hospitals that enrolled patients between October 3,2012,and September 21,2017.Four hundred patients with stage I or II pancreatic head cancer and without specific pancreatic cancer treatments(preoperative chemotherapy or chemoradiation)within three months were randomly assigned to undergo standard pancreatoduodenectomy(SPD)or EPD,with the latter followed by dissection of additional lymph nodes(LNs),nerves and soft tissues 270◦on the right side surrounding the superior mesenteric artery and celiac axis.The primary endpoint was overall survival(OS)by intention-to-treat(ITT).The secondary endpoints were disease-free survival(DFS),mortality,morbidity,and postoperative pain intensity.Results:TheR1 ratewas slightly lower with EPD(8.46%)thanwith SPD(12.56%).The morbidity and mortality rates were similar between the two groups.The median OS was similar in the EPD and SPD groups by ITT in the whole study cohort(23.0 vs.20.2 months,P=0.100),while the median DFS was superior in the EPD group(16.1 vs.13.2 months,P=0.031).Patients with preoperative CA19–9<200.0 U/mL had significantly improved OS and DFS with EPD(EPD vs.SPD,30.8 vs.20.9 months,P=0.009;23.4 vs.13.5 months,P<0.001).The EPD group exhibited significantly lower locoregional(16.48%vs.35.20%,P<0.001)andmesenteric LNrecurrence rates(3.98%vs.10.06%,P=0.022).The EPD group exhibited less back pain 6 months postoperation than the SPD group.Conclusions:EPD for pancreatic head cancer did not significantly improve OS,but patients with EPD treatment had significantly improved DFS.In the subgroup analysis,improvements in bothOS and DFS in the EPD armwere observed in patients with preoperative CA19–9<200.0 U/mL.EPD could be used as an effective surgical procedure for patients with pancreatic head cancer,especially those with preoperative CA19–9<200.0 U/mL. | Qing Lin Shangyou Zheng Xianjun Yu Meifu Chen Yu Zhou Quanbo Zhou Chonghui Hu Jing Gu Zhongdong Xu LinWang Yimin Liu Qingyu Liu MinWang Guolin Li He Cheng Dongkai Zhou Guodong Liu Zhiqiang Fu Yu Long Yixiong Li Weilin Wang Renyi Qin Zhihua Li Rufu Chen | 2023 | Cancer Communications2023，43，2： | 3 |
| 4 | Possible radio precursors/signatures of the CMEs onset:radio type Ⅲ bursts and fine structures in the centimeter-metric wavelength region显示文摘Seventy-one occurrences of coronal mass ejections(CMEs) associated with radio bursts,seemingly associated with type Ⅲ bursts/fine structures(FSs),in the centimeter-metric frequency range during 2003-2005,were obtained with the spectrometers at the National Astronomical Observatories,Chinese Academy of Sciences(NAOC) and the Culgoora radio spectrometer and are presented.The statistical results of 68 out of 71 events associated with the radio type III bursts or FSs during the initiation or early stages of the CMEs indicate that most CMEs contain the emissions of radio type Ⅲ bursts/FSs near the time of the CME's onset,in spite of their fast or slow speeds.Therefore,we propose that type Ⅲ bursts and FSs are possible precursors of the onset of CMEs.We stress that the radio type Ⅲ bursts/FSs in the centimetermetric wavelength region and the CME transients possibly occurred in conjunction with the origin of the coronal precursor structures.Thus,the statistical results support the suggestions that type Ⅲ bursts/FSs are indicators of extra energy input into the corona at the CMEs' onset,and that the type Ⅲ bursts/FSs are produced primarily due to a coronal instability which eventually triggers the CME process.This may signify that the centimeter-metric radio bursts corresponding to or near the CME's onset are caused by the disturbed corona(possibly including minor magnetic reconnections). | MinWang Guan-NanGa01 Rui-XiangXie Cheng-MingTan | 2011 | Research in Astronomy and Astrophysics2011，11，5： | 2 |
| 5 | The study of a self-frequency-doubling laser crystal Nd^3+:GdAl3(BO3)4显示文摘 | Tu Chaoyang Qiu Minwang Huang Yichuan Chen Xueyuan Jiang Aidong Luo Zundu | 2000 | Journal of Crystal Growth2000，208，14： | 1 |
| 6 | Gene transfer and expression of enhanced green fluorescent protein in variant HT-29c cells显示文摘AIM: To study the expression of enhanced green fluorescent protein (EGFP) gene in retrovirally transduced variant HT29 cells.METHODS: The retroviral vector prkat EGFP/neo was constructed and transfected into the 293T cell using a standard calcium phosphate precipitation method. HT-29c cells (selected from HT-29 cells) were transduced by a retroviral vector encoding the GEFP gene. The fluorescence intensity of colorectal carcinoma HT-29c cells after transduced with the EGFP bearing retrovirus was visualized using fluorescence microscope and fluorescence activated cell sorter (FACS) analysis. Multiple biological behaviors of transduced cells such as the proliferating potential and the expression of various antigens were comparatively analyzed between untransduced and transduced cells in vitro. EGFP expression of the fresh tumor tissue was assessed in vivo.RESULTS: After transduced, HT-29c cells displayed a stable and long-term EGFP expression under the nonselective conditionsin vitro. After cells were successively cultured to passage 50 in vitro, EGFP expression was still at a high level. Their biological behaviors, such as expression of tumor antigens, proliferation rate and aggregation capability were not different compared to untransduced parental cells in vitro. In subcutaneous tumors, EGFP was stable and highly expressed.CONCLUSION: An EGFP expressing retroviral vector was used to transduce HT-29c cells. The transduced cells show a stable and long-term EGFP expression in vitro and in vivo.These cells with EGFP are a valuable tool forin vivo research of tumor metastatic spread. | MinWang LarsBoenicke BradleyD.Howard IlkaVogel HolgerKalthoff | 2003 | World Journal of Gastroenterology2003，9，9： | 1 |
| 7 | Is Real Estate Really an Inflation Hedge? Evidence from Taiwan*显示文摘 | Wen‐ShwoFang Kuan‐MinWang Thanh‐Binh T.Nguyen | 2008 | Asian Economic Journal2008，，2： | 1 |
| 8 | From spent Mg/A1 layered double hydroxide to porous carbon materials 显示文摘 | Laipan Minwang Zhu Rurdiang Chert Qingze | 2015 | J Hazard Mater2015，300，： | 1 |
| 9 | Sox 17, the canonical Wnt an-tagonist, is epigenetically inactivated by promoter methylation in hu-man breast cancer显示文摘 | YuanFu D MinWang Z Chen L | 2010 | Breast Cancer Res Treat2010，119，8： | 1 |
| 10 | Zingiber officinale (ginger) compounds have tetracycline‐resistance modifying effects against clinical extensively drug‐resistant Acinetobacter baumannii显示文摘 | Hui‐MinWang Chung‐YiChen Hsi‐AnChen Wan‐ChunHuang Wei‐RuLin Tun‐ChiehChen Chun‐YuLin Hsin‐JuChien Po‐LiangLu Chiu‐MeiLin Yen‐HsuChen | 2010 | Phytother Res2010，，12： | 1 |
| 11 | A Probable Short Decimetric Type Ⅰ-like Noise Storm: Associated with Type Ⅲ Bursts?显示文摘A rare Type I-like noise storm was observed with the solar radio spectrometers (1.0-2.0 GHz and 2.60-3.8 GHz) at National Astronomical Observatories of China (NAOC) on September 23, 1998. We concentrate on checking the Type I-like noise storm occurred in the decay phase of a Type IV radio burst. This noise storm consists of many Type I bursts and isolated Type III or Type III pair bursts.It has a bandwidth of ≤ 0.5 GHz. The duration of each Type I burst is of the order of 100-300ms. The total duration is greater than 11 minutes. The circular polarization degree of the components of Type I and associated Type III bursts are about 40%-100% and almost 100%, respectively, which is greater than that of the background continuum (nearly the precision of our instrument). This short decimetric Type I-like storm may be another kind or the extension of the kind of metric Type I storm, and may possess the duality of metric and decimetric radio emission. It may be in favor of an earlier emission mechanism of the fundamental plasma radiation due to the coalescence of Langmuir waves with low-frequency waves. | Rui-XiangXie MinWang Yi-HuaYan | 2005 | Chinese Journal of Astronomy and Astrophysics2005，5，1： | 1 |
| 12 | Increased PD‐1 and decreased CD28 expression in chronic hepatitis B patients with advanced hepatocellular carcinoma显示文摘 | Ping‐NingHsu Tsuey‐ChingYang Jung‐TaKao Ken‐ShengCheng Yi‐JuLee Yuan‐MinWang Chin‐TungHsieh Cheng‐WenLin Yi‐YingWu | 2010 | Liver International2010，，9： | 1 |
| 13 | Purification and identification of three novel antioxidant peptides from Cornu 显示文摘 | Rui Liua MinWang Jin - ao Duan | 2010 | Peptides2010，31，： | 1 |
| 14 | Prevalence and Control of Diabetes in Chinese Adults显示文摘 | Yu Xu Li minWang Jiang He | 2013 | JAMA2013，310，9： | 1 |
| 15 | The growth of Nd3+ :GdxY1-xAl3(BO3)4 crystals显示文摘 | TU Chaoyang HUANG Yichuan QIU Minwang | 1999 | Journal of Crystal Growth1999，206，3： | 1 |
| 16 | Genetic and pharmacological evidence for schizophrenia‐related Disc1 interaction with GSK‐3显示文摘 | Tatiana V.Lipina OksanaKaidanovich‐Beilin SatishPatel MinWang Steven J.Clapcote FangLiu James R.Woodgett John C.Roder | 2010 | Synapse2010，，3： | 1 |
| 17 | Sequential therapy achieves a higher eradication rate than standard triple therapy in Taiwan显示文摘 | Feng‐WoeiTsay Hui‐HwaTseng Ping‐IHsu Kai‐MingWang Ching‐ChangLee Shiuh‐NanChang Huay‐MinWang Hsien‐ChungYu Wen‐ChiChen Nan‐JingPeng Kwok‐HungLai Deng‐ChyangWu | 2012 | Journal of Gastroenterology and Hepatology2012，，3： | 1 |
| 18 | Large-Scale Distribution of Herbig-Haro Objects in Taurus显示文摘We report our new results on Herbig-Haro (HH) objects in the star forming region of Taurus from a wide-field survey with the 60/90 cm Schmidt telescope of the Beijing Astronomical Observatory. This survey using CCD imaging with a narrow band [SⅡ] filter and an intermediate band [BATC10] filter covered approximately 30 square degrees in Taurus. Besides confirming the known HH Objects in the region, we discovered seven new HH candidates, and groups. Six of these are HH 701A-B, HH 702A-D, HH 703, HH 704A-D, HH 705, HH 706 and the seventh is a group, a new component of HH 319, labeled HH 319B-D. Based on the large-scale distribution of pre-main-sequence (PMS) stars in Taurus, we analyze statistically the most probable distance from the HH objects to each PMS star,from which we estimate the typical timescale of these HH objects to be between(1.3 - 2.0) × 104 yrs; and we also obtain the birth rates of HH objects: 0.447±0.198 for Class Ⅰ PMS stars, 0.360±0.222 for Class Ⅱ PMS stars, and -0.148±0.234 for Class Ⅲ PMS stars. | Ke-FengSun JiYang Shao-GuangLuo MinWang Li-CaiDeng | 2003 | Chinese Journal of Astronomy and Astrophysics2003，3，5： | 0 |
| 19 | IS EUROPE IN DECLINE?显示文摘It is time to re-evaluate the strength and influence of the power bloc On May 12,the European Parliament passed a non-binding resolution refusing to grant China market economy status.It came as little surprise for many long-term observers of Europe,who have argued that the EU is trying to externalize its internal problems.The resolution can be interpreted as an EU protectionist strategy,seeking to limit the entry of Chinese products. | Lin Minwang | 2016 | Beijing Review2016，59，21： | 0 |
| 20 | Boao 2016 Recharges Asian Economy显示文摘THE 15th Boao Forum for Asia,convened in late March,was one of the first major diplomatic events China hosted this year.After years of development the event has built | LIN MINWANG | 2016 | China Today2016，65，4： | 0 |
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