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    题名 作者 年代 出处 被引量
1Expression of E-cadherin and β-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survival显示文摘AIM:The E-cadherin-catedin complex is important for cell-cell adhesion of epithelial cells.Impairment of one or more components of this comples is associated with poor differentiation and increased invasiveness of carcinomas,We evaluated the expression pattern of E-cadherin and β-catenin in gastric carcinoma and dysplasia and analyzed their relationship with tumor clinicopathological featrres and patient survival.Yong-NingZhou Cai-PuXu BiaoHan MinLi LiangQiao Dian-chunFang J 2002World Journal of Gastroenterology2002,8,6:41
2Inhibition of Fas/FasL mRNA expression and TNF-a release in concanavalin A-induced liver injury in mice by bicyclol显示文摘AIM: Bicyclol, 4,4'-dimethoxy-5,6,5',6'-dimethylene-dioxy-2-hydroxymethy1-2'-carbonyl biphenyl, is a new anti-hepatitis drug. The aim of the present study was to investigate the protective effect of bicyclol on concanavalin A (Con A)-induced immunological liver injury in mice and its mechanism. METHODS: Liver injury was induced by injection of Con A via tail vein of mice and assessed biochemically and histologically. Serum transaminase and tumor necrosis factor alpha (TNF-a were determined. Liver lesions were observed by light microscope. Expressions of TNF-a, interferon gamma (IFN-y), Fas and Fas ligand (FasL) mRNA in the livers were measured by RT-PCR. RESULTS: Serum transaminase level and liver lesions in Con A-induced mice were markedly reduced by oral administration of 100, 200 mg/kg of bicyclol. TNF-a level inserum was also reduced by bicyclol. Con A injection in ducedup-regulation of TNF-a, IFN-7, Fas and FasL mRNA expression in liver tissues. Bicyclol significantly down-regulated the expression of IFN-y, Fas and FasL mRNA, but only slightly affected TNF-a mRNA expression in liver tissues. CONCLUSION: Bicyclol protects against Con A-induced liver injury mainly through inhibition of Fas/FasL mRNA expression in liver tissues and TNF-a release in mice.MinLi Geng-TaoLiu 2004World Journal of Gastroenterology2004,10,12:23
3Mining microblog user interests based on TextRank with TF-IDF factor显示文摘It is of great value and significance to model the interests of microblog user in terms of business and sociology.This paper presents a framework for mining and analyzing personal interests from microblog text with a new algorithm which integrates term frequency-inverse document frequency(TF-IDF) with TextRank.Firstly, we build a three-tier category system of user interest based on Wikipedia.In order to obtain the keywords of interest, we preprocess the posts, comments and reposts in different categories to select the keywords which appear both in the category system and microblogs.We then assign weight to each category and calculate the weight of keyword to get TF-IDF factors.Finally we score the ranking of each keyword by the TextRank algorithm with TF-IDF factors.Experiments on real Sina microblog data demonstrate that the precision of our approach significantly outperforms other existing methods.Tu Shouzhong Huang Minlie 2016The Journal of China Universities of Posts and Telecommunications2016,23,5:19
4Recent advances and challenges in task-oriented dialog systems显示文摘Due to the significance and value in human-computer interaction and natural language processing,task-oriented dialog systems are attracting more and more attention in both academic and industrial communities.In this paper,we survey recent advances and challenges in task-oriented dialog systems.We also discuss three critical topics for task-oriented dialog systems:(1)improving data efficiency to facilitate dialog modeling in low-resource settings,(2)modeling multi-turn dynamics for dialog policy learning to achieve better task-completion performance,and(3)integrating domain ontology knowledge into the dialog model.Besides,we review the recent progresses in dialog evaluation and some widely-used corpora.We believe that this survey,though incomplete,can shed a light on future research in task-oriented dialog systems.ZHANG Zheng TAKANOBU Ryuichi ZHU Qi HUANG MinLie ZHU XiaoYan 2020Science China(Technological Sciences)2020,63,10:8
5Clinical Evaluation of Color Doppler Ultrasound in Selecting the Optimal Treatment Modality for Infantile Hemangioma显示文摘客观我们调查了 1064 nm Nd 的功效和安全:钇铝柘榴石激光,强烈的搏动的光( IPL ),和在 hemangioma 的治疗的 lauromacrogol 注射,作为 hemangiomas 诊断了以便在选最佳的治疗 modality.Methods 为临床的婴儿的病人评估颜色 Doppler 超声指导的价值随机被划分成组 A ,谁在治疗,和组 B 前有颜色 Doppler 超声考试没有超声评估,有治疗。在组 A 的病人被 sonography 根据损害的深度分配进亚群:为有损害深度的那些的组 A-1 < 1.2 公里,并且诊脉轻治疗;为有损害深度 1.2mm 的那些的组 A-2 并且 < 3 公里,并且诊脉 1064 nm Nd : 钇铝柘榴石激光治疗;为有损害深度 3mm 的那些的组 A-3 并且 < 5 公里,并且被与长脉搏相结合的 IPL 对待 1064 nm Nd : 钇铝柘榴石激光治疗;为有损害深度的那些的组 A-4 5 公里,并且拿了 lauromacrogol 注射治疗。在组 B 的病人诊脉 1064 nm Nd : 没有外科手术前的超声评估的钇铝柘榴石激光治疗。功效和在这些组之间的治疗的不利反应完全被评估并且比较 statistically.Results 有 128 皮肤损害的 113 个病人在这研究被注册, 85 在组 A (吝啬的年龄 6.8 吗??MinLi JuanLiu ValeskaMaya DanLuo Bingrong Zhou 2017Chinese Medical Sciences Journal2017,32,2:6
6Acquisition algorithm assisted by AGC control voltage for DSSS signals显示文摘An appropriate acquisition configuration in terms of signal quality can optimize the acquisition performance. In view of this, a new approach of acquisition assisted by the control voltage of automatic gain control(AGC) is proposed. This approach judges the signal power according to the AGC control voltage and switches the working modes correspondingly and adaptively. Non-coherent accumulation times and the detection threshold are reconfigured according to the working mode. Theoretical derivation and verification by simulation in typical situations are provided, and the algorithm is shown to be superior in terms of the mean acquisition time, especially in strong signal scenarios compared with the conventional algorithm.SHEN YuYao WANG YongQing LIU MinLi WU SiLiang 2015Science China(Technological Sciences)2015,58,12:4
7Advancement of maxillary anterior segment by distraction osteogenesis for severe maxillary retrusion in cleft lip and palate显示文摘Gao Feng Yang Minlie Zhao Zhenmin Sun Xiaomei Yin Ningbei Wang Yongqian Song Tao Li Haidong Wu Di Yin Jiapeng Cao Yimei Tong Haizhou 2014Chinese Medical Journal2014,,3:4
8Cross-correlation function based multipath mitigation technique for cosine-BOC signals显示文摘We propose a new multipath mitigation technique based on cross-correlation function for the new cosine phased binary offset carrier(cosine-BOC) modulated signals, which will most likely be employed in both European Galileo system and Chinese Compass system. This technique is implemented to create an optimum cross-correlation function via designing the modulated symbols of the local signal. And the structure of the code tracking loop for cosine-BOC signals is quite simple including only two real correlators. Results demonstrate that the technique efficiently eliminates the ranging errors in the medium and long multipath regions with respect to the conventional receiver correlation techniques.Huihua Chen Weimin Jia Minli Yao 2013Journal of Systems Engineering and Electronics2013,24,5:3
9DEALING WITH SPATIAL RELATIONS FOR SPATIAL OBJECTS WITH RANDOMNESS IN GIS显示文摘To design retrieval algorithm of spatial relations for spatial objects with randomness in GIS,this paper builds up the membership functions based on set theory idea,used for determination of topological spatial relations between random objects,such as between point and point,point and line or polygon,which provides theoretical basis for retrieving spatial relations between certain and random objects.Finally,this paper interprets detailed methods and steps of realizing them by means of some simple examples under the GIS’s environment.DENG MinLI ChengmingLIU Wenbao 2001Geo-Spatial Information Science2001,4,4:2
102-D DIRECTION FINDING OF COHERENT SIGNALS VIA TEMPORO-SPATIAL PROCESSING显示文摘In most wireless communication systems, two-dimensional Directions-Of-Arrival (DOA) of multipath signals need to be found for spatial selective transmission. However, it is quite difficult to find their DOAs due to the coherent nature of multipath signals and considerable computations when performing 2-D searches. In this paper, a new algorithm to estimate 2-D DOA of multiple narrow-band signals is proposed. A DOA cyclic matrix is constructed whose eigenvalues and eigenvectors can be simultaneously used to extract 2-D DOA without 2-D searches. By exploiting the temporal property of cyclostationarity, the signal detection capability is significantly improved. Besides, based on the decorrelation model for mobile terminal signals, the algorithm can be effectively extended to the coherent case without spatial smoothing and the loss of array aperture. Simulation results are given to illustrate the performance of the new algorithm.Jin Liang (PLA Information Engineering College, 1001 P. O. Box 6-5#, Zhengzhou 450002)Yao Minli Yin Qinye (Institute of Information Engineering, Xi’an Jiaotong University, Xi’an, 710049) 2000Journal of Electronics(China)2000,17,1:2
11Finding Nuggets in Patent Portfolios: Core Patent Mining and Its Applications显示文摘Patents are critically important for a company to protect its core business concepts and proprietary technologies. Effective patent mining in massive patent databases not only provides business enterprises with valuable insights to develop strategies for research and development, intellectual property management, and product marketing, but also helps patent offices to improve efficiency and optimize their patent examination processes. This paper describes the patent mining problem of automatically discovering core patents (i.e., novel and influential patents in a domain). In addition, the value of core patent mining is illustrated by revealing the potential competitive relationships among companies in their core patents. The work addresses the unique patent vocabulary usage which is not considered in traditional word-based statistical methods with a topic-based temporal mining approach that quantifies a patent's novelty and influence through topic activeness variations. Tests of this method on real-world patent portfolios show the effectiveness of this approach over state-of-the-art methods.Po Hu Minlie Huang Xiaoyan Zhu 2013Tsinghua Science and Technology2013,18,4:2
12c-Jun binding site identification in K562 cells显示文摘决定抄写因素的有约束力的地点为 transcriptional 规定的理解是重要的。抄写因素 c6 月戏在细胞生长,区别和开发的一个重要角色,而是有约束力的地点和目标基因清楚地没在整个人被定义染色体。在这研究,我们执行了一个 ChIP-Seq 实验在人的染色体识别 c6 月绑定地点。48 个有约束力的地点被选择由 dsDNA microarray 试金处理进一步的评估。我们在 K562 房间识别了 283 个 c6 月绑定地点。数据分析证明 48.8% 有约束力的地点在 100 以内定位了 kb 注解基因在上游, 28.6% 有约束力的地点包括了一致 TRE/CRE 主题(5-TGAC/GTCA-3, 5-TGACGTCA-3 ) 并且变体序列。42 从选择了地点被发现在 dsDNA microarray 分析绑 c6 月 homodimer 的 48 绑定。数据分析也证明 1569 基因在 dsDNA microarray 验证的 42 个有约束力的地点的邻居位于 283 个有约束力的地点和 191 基因的邻居。我们在以前的研究请教了 38 c6 月目标基因, 16 也在这研究在这 38 基因之中被检测。在染色体规模的 c6 月绑定地点和潜在的目标基因的鉴定可以在位于与 c6 月有关的抄写规定下面的分子的机制改进我们的基本理解。Minli Li Qinyu Ge Wei Wang Jinke Wang Zuhong Lu 2011Journal of Genetics and Genomics2011,38,6:2
13加卸载响应比(LURR)、矩/能量加速释放(AM/ER)、态矢量:岩石试件破坏前兆的实验研究显示文摘为了验证大地震发生前或者非均匀脆性介质宏观破坏前加卸载响应比和能量加速释放等前兆现象,本文进行了三轴应力(压缩)条件下大尺度岩石破坏声发射实验。实验采用4组岩石试件,并且分为单调加载和循环加载两种方式。实验结果证明了脆性材料宏观破坏前加卸载响应比升高和能量加速释放这两种前兆现象。本文提出了一种描述岩石试件损伤演化的新的物理量——态矢量。Xiang-ChuYin Huai-ZhongYu V.Kukshenko Zhao-YongXu ZhishenWU MinLi KeyinPeng S.Elizarov QiLi 张晖辉 颜玉定 尹祥础 2005世界地震译丛2005,,2:2
14Efficacy of Chaihu Jisang decoction on post-infection cough and its effect on cough reflex sensitivity显示文摘OBJECTIVE:To investigate the efficacy of Chaihu Ji Sang Decoction(CJSD),(a modification of Xiao Chaihu Tang(Minor Decoction of Bupleurum) was evaluated in patients with post-infection cough(PIC).Its effect on cough reflex sensitivity(CRS) was also described.METHODS:One hundred and eighteen patients with PIC were enrolled and randomly divided into an experimental group and control group(54 patients in each group).The experimental group was given CJSD orally,and the control group was given cetirizine hydrochloride for 7 d.Cough symptom scores and TCM symptom scores were compared before and after treatment.Efficacy,cough onset time,recurrence,and adverse drug reactions were additionally evaluated.Finally,CRS was evaluated before and after treatment of PIC patients in the experimental group.RESULTS:Fifty-two patients in the experimental group and fifty control patients completed the study.Cough symptom scores and the TCM symptom scores of the two groups were significantly improved after treatment,however cough symptoms in the experimental group 1(0,2) were significantly lower than the control group 2(1,2) after treatment(P < 0.05).Similarly,TCM symptom scores 4(0,7) in the experimental group were significantly lower than the control group 6(3,12)(P < 0.01).Overall,the effective rate of the experimental treatment(84.60%) was significantly higher than that of the control treatment(68.00%)(P < 0.01).The onset time of efficacy of the experimental treatment was one day faster than the control treatment [2(2,3) d vs 3(2,3) d,P < 0.01].The relapse rate in the experimental group(9.09%) was lower than that of the control group(29.41%)(P < 0.05).39 PIC patients in the experimental group completed a capsaicin cough challenge test before treatment.The lgC2 and lg C5 of the experimental group prior to treatment was 1.19(0.59,1.49) and 1.80(1.49,2.10),respectively.The lgC2,lg C5 of the healthy control group was 1.49(0.89,2.40) and 2.70(2.40,3.00),respectively.The differences in lgC2 and lg C5 between experimental group and healthy groups were significant at this time point(both P < 0.01).After treatment,34 patients in the experimental group received re-examination.lg C5 increased from 1.80(1.49,2.10) to 2.10(1.49,3.00).CRS after treatment/re-examination was significantly lower than those of baseline in the experimental group(P < 0.05).CONCLUSION:CJSD could effectively improve the clinical symptoms of PIC patients,with demonstrable low recurrence and safety.CJSD also significantly decreased the CRS in patients with PIC.Hong Minli Huang Baopei Hong Chunlin Chen Huinuan Chen Wenxi Liu Chaohui Li Xinjian Li Candong 2018Journal of Traditional Chinese Medicine2018,38,4:2
15Low concentrations of the recombinant toxin protein rLj-RGD3 suppress TNF-a-induced human renal carcinoma cell invasion显示文摘肾的房间癌(RCC ) 的一个特点侵略由 gelatinase 酶的本地生产是细胞外的矩阵(ECM ) 的降级。矩阵 metalloproteinase-9 (MMP-9 ) 导致了癌症房间侵略是在癌症的枢轴的步之一转移。它被报导了那个肿瘤坏死因素 --(TNF-) , MMP-9 的一个管理者,能在人的肾的癌房间导致侵略。在我们的实验室的以前的工作显示出那 rLj-RGD3,从 Lampetra 装饰用的梨树的口腔的腺分泌物的 recombinant RGD (ArgGlyAsp ) 毒素蛋白质,拥有反肿瘤活动。在这研究,我们证明 rLj-RGD3 压制了 TNF -- 在 786-0 房间(人的肾的癌房间) 的导致的 MMP-9 分泌物。在 TNF 上调查 rLj-RGD3 的规章的效果 -- 导致的 MMP-9 分泌物,我们预先对待有 rLj-RGD3 的房间。有趣地, rLj-RGD3 没在 MMP 的组成的分泌物上有重要效果。然而, rLj-RGD3 的低集中减少了 TNF -- 导致的 MMP-9 分泌物。功能的研究表明 rLj-RGD3 导致了 apoptosis 并且显著地禁止了 786-0 房间的增长,迁居,和侵略。而且,在房间的肌动朊建筑学与 rLj-RGD3 预先对待被聚集并且瓦解。我们的调查结果建议 rLj-RGD3 可以在肾的癌症被用作潜在的药治疗。Minli Jin Rong Xiao Jihong Wang Xin Liu Yu Liu Zhuang Xue Li Lv Yuanyuan Zheng Qingwei Li 2013Acta Biochimica et Biophysica Sinica2013,45,5:2
16Discovering patterns to extract protein-protein interactions from full texts 显示文摘Huang Minlie Zhu Xiaoyan Hao Yu 2004Bioinformatics2004,20,18:1
17Discovering patterns to extract protein-protein interactions from the literature : Part Ⅱ 显示文摘Hao Yu Zhu Xiaoyan Huang Minlie 2005Bioinformaties2005,21,15:1
18Discoveringpatterns to extract protein-protein interactions from full texts显示文摘HUANG Minlie ZHU Xiaoyan HAO Yu 2004Bioinformatics2004,20,18:1
19Effect of Yufeining on induced sputum iuterleukin-8 in patients with chronic obstructive pulmonary disease at the stable phase 显示文摘HONG MINLI YAN G GUOZONG CHEN WENX 2005Chinese Journal of Integrated Medicine2005,11,3:1
20A hybrid method for relation extraction from biomedical literature 显示文摘Huang Minlie Zhu Xiaoyan Li Ming 2006International Journal of Medical Informatics2006,75,6:1
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