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| 1 | Fractal analysis of retinal vasculature in normal subjects on ultra-wide field fluorescein angiography显示文摘AIM: To evaluate the fractal feature of the retinal vasculature of normal eyes on a stereographic projected and montaged ultra-wide field(UWF) fluorescein angiography(FA).METHODS: Prospective, observational, cross-sectional study. Totally 59 eyes of 31 normal subjects were imaged using the Optos 200 Tx. Images obtained at different gaze angles stereographically projected and montaged. The early-phase UWF FA frames were processed to segment the retinal vasculature and the results were exported as binary masks. The fractal dimension(FD) was calculated using the box-counting method.RESULTS: The global FD for the entire retina was 1.6±0.04, with no difference between males and females(1.59±0.04 vs 1.61±0.04, P=0.084) or between right and left eyes(1.6±0.04 vs 1.6±0.05, P=0.61). FD was nonuniformly distributed among four quadrants(P<0.001) and decreased as the distance from the fovea increased(P<0.001). A negative association was observed between FD and age(R=-0.37, P=0.006), and this relationship was observed in the posterior and mid-peripheral retina(P<0.05) but absent in far-periphery(P>0.05).CONCLUSION: Fractal geometry is non-uniformly distributed across the retina in normal eyes and decreases from the fovea to the far-periphery. Subjects with an older age tend to have a smaller FD, however, the FD in the farperiphery does not appear to be influenced by age. | Wen-Ying Fan Alan Fleming Gavin Robertson Akihito Uji Jano van Hemert Michael Singer Min Sagong Michael Ip SriniVas R.Sadda | 2020 | International Journal of Ophthalmology(English edition)2020，13，7： | 3 |
| 2 | Anti–Vascular Endothelial Growth Factor Pharmacotherapy for Diabetic Macular Edema显示文摘 | Allen C. Ho Ingrid U. Scott Stephen J. Kim Gary C. Brown Melissa M. Brown Michael S. Ip Franco M. Recchia | 2012 | Ophthalmology2012，，10： | 2 |
| 3 | Fluocinolone Acetonide Intravitreal Implant for Diabetic Macular Edema: A 3-Year Multicenter, Randomized, Controlled Clinical Trial显示文摘 | P. Andrew Pearson Timothy L. Comstock Michael Ip David Callanan Lawrence S. Morse Paul Ashton Brian Levy Eric S. Mann Dean Eliott | 2011 | Ophthalmology2011，，8： | 2 |
| 4 | Altered upper airway and soft tissue structures in the New Zealand obese mouse显示文摘 | Michael JB Allan IP Kei K | 2009 | Am J Respir Crit Care Med2009，179，2： | 1 |
| 5 | Kallikreins as markers of disseminated tumour cells in ovarian cancer-a pilot study 显示文摘 | Oikonomopoulou K Scorilas A Michael IP | 2006 | Tumour Biol2006，27，2： | 1 |
| 6 | piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells显示文摘 | Woltjen K Michael IP Mohseni P | 2009 | Nature2009，458，7239： | 1 |
| 7 | PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells显示文摘 | Woltjen K Michael IP Mohseni P | 2009 | Nature2009，458，7239： | 1 |
| 8 | Human tissue kal- likreins:physiologic roles and applications in cancer显示文摘 | Borgono CA Michael IP Diamandis EP | 2004 | Mol Cancer Res2004，2，5： | 1 |
| 9 | piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells 显示文摘 | Wohjen K Michael IP Mohseni P | 2009 | Nature2009，458，： | 1 |
| 10 | piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells显示文摘 | Woltjen K Michael IP Mohseni P | | 0，，7239： | 1 |
| 11 | Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases显示文摘 | Benjamin J Cowling Lianmei Jin Eric HY Lau Qiaohong Liao Peng Wu Hui Jiang Tim K Tsang Jiandong Zheng Vicky J Fang Zhaorui Chang Michael Y Ni Qian Zhang Dennis KM Ip Jianxing Yu Yu Li Liping Wang Wenxiao Tu Ling Meng Joseph T Wu Huiming Luo Qun Li Yuelong | 2013 | The Lancet2013，，9887： | 1 |
| 12 | piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells 显示文摘 | Woltjen K Michael IP Mohseni P | 2009 | Nature2009，458，： | 1 |
| 13 | Human tissue kallikreins: physiologic roles and applications in cancer 显示文摘 | Borgono CA Michael IP Diamandis EP | 2004 | Mol Cancer Res2004，2，5： | 1 |
| 14 | Human tissue kallikreins:physiologic roles and applications in cancer显示文摘 | Borgono CA Michael IP Diamandis EP | 2004 | Mol Cancer Res2004，2，5： | 1 |
| 15 | Kallikreins as markers of disseminated tumour cells in ovarian cancer-a pilot study显示文摘 | Oikonopoulou K Scorilas A Michael IP | 2006 | Tumor Biol2006，27，2： | 1 |
| 16 | Human tissue kallikrein 5 is a member of a proteolytic cascade pathway inw)lved in seminal clot liqoefaction and potentially in prostate cancer pro- gression显示文摘 | Michael IP Pampalakis G Mikolajezyk SD | 2006 | J Biol Chem2006，281，12： | 1 |
| 17 | A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation显示文摘 | Borgoflo CA Michael IP Komatsu N | 2007 | J Biol Chem2007，282，6： | 1 |
| 18 | PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells显示文摘 | Woltjen K Michael IP Mohseni P | 2009 | Nature2009，458，7239： | 1 |
| 19 | Human tissue kallikrein:physiologic roles and applications in cancer显示文摘 | Borgono CA Michael IP Diamandis EP | 2004 | Mol Cancer Res2004，2，5： | 1 |
| 20 | On Site Repair of l)amged and Severely Eroded Low Pressure Turbine Blodes Without Removal of Any Blmles from the Rotor显示文摘 | FRANKLIN PHII IP C FRASER MICHAEl J | 1993 | Proceedings of the American Power Conference1993，55，2： | 1 |
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