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| 1 | Interplay between nitric oxide and VIP in CCK-8-induced phasic contractile activity in the rabbit sphincter of Oddi显示文摘AIM: The sphincter of Oddi (SO) plays an important role in delivery of bile into the duodenum. To establish whether vasoactive intestinal polypeptide (VIP) and nitric oxide (NO) were involved in phasic contractile activity of the rabbit SO stimulated by cholecystokinin-octapeptide (CCK-8).METHODS: Isolated SO muscle rings were cleaned of fat and mounted horizontally on two small L-shaped hooksone of which was connected to a force transducer for the measurement of isometric tension. The experiments were carried out in a thermostatically controlled (37±0.2℃)organ bath (5 mL) containing Krebs solution. The organ fluid was gassed with 95% O2 and 50 mL/L CO2 to keep the pH at 7.40±0.05. Contractile responses to CCK-8 (1μmol/L) were evaluated in the presence and absence of N^G-nitro-L-arginine (LNNA), an inhibitor of NO synthase (100μmol/L), and (p-chloro-D-Phe^6-Leu^17)-VIP (VIPa,30μmol/L), a VIP receptor antagonist.RESULTS: CCK-8 stimulated the phasic activity of the SO.NO synthase inhibition increased the frequency and amplitude of contractions with a slight increase in developed tension.Pre-incubation with VIPa also attenuated this CCK-8 effect.The combined application of LNNA and VIPa abolished the phasic activity of the muscle rings with a marked increase in tension in response to CCK-8.CONCLUSION: VIP and NO together contribute to an increase in phasic activity of SO. | Attila Pálv(o|¨)lgyi Réka Sári József Németh Annamária Szabolcs István Nagy Péter Hegyi János Lonovics Zoltán Szilvássy | 2005 | World Journal of Gastroenterology2005，11，21： | 11 |
| 2 | 斯洛伐克西喀尔巴阡山脉内侧Veporicum地区的地球动力学演化序列与菱镁矿和滑石矿床成因(英文)显示文摘本文总结并报导了斯洛伐克西喀尔巴阡山脉内侧的石炭纪岩石中产出的菱镁矿和滑石成因的最新资料.这些矿床赋存于Veporicum构造超单元中和该超单元与Gemericum的接触带中.北部Sinec成矿带是主要的菱镁矿和滑石矿化区,产出的主要矿床有Kokava,Sinec,Samo,Hnsta-Mutnik等矿床.而南部的Ochtina成矿带只产有菱镁矿床,主要矿床包括在Dubrava地体上的Dubrava,Mikov?JedL'vec;Luben韐,Ochtina,Kosice-Bankov,Banisko,Medvedia等矿床.菱镁矿形成于变质M1期石炭系中方解石被白云石和菱镁矿连续交代过程(北矿带成矿温度为280~400℃,南矿带成矿温度为370~420℃;Radvanec&Prochska,2001;Kodera&Radvanec,2002).Permoscythian蒸发卤水提供了Mg.成矿事件和华力西期碰撞后运动有关.拉伸构造和高热流值促使成矿热液系统的产生.滑石矿化则形成于稍晚的不同期变质事件(M2),成矿流体来源也与菱镁矿化不同.构造的、微构造的、变质的以及地质年代学的数据将滑石成矿作用和阿尔卑斯上白垩系的构造地热事件AD2联系在一起.AD2事件是阿尔卑斯碰撞(AD1)地壳加厚和变质核杂岩体起源的结果,体现在地壳不整合面上的区域拉伸,及开放系统中大规模热液流动.这一过程在更靠近Veporic热穹的北带区域(Sinec剪切带)很显著,而向着Veporic热穹的周围部分(南Ochtina带),M2变质过程和块滑石化则逐渐减弱.Sinec剪切带是北Sinec带中突出的AD2-AD3结构,白云石/菱镁矿透镜体(在M1期交代造成的)和相伴随的岩石夹杂在AD1中更坚硬的基底岩石之中.本研究证明了AD2中块滑石化的普遍性,滑石和白云石2形成于拉伸显微构造中(变质过程M2;温度为490~540℃,压力为240~330MPa).在Sinec带中AD3阶段的对偶剪切作用形成了该带中的滑石矿.它是AD2事件从去顶到区域扭压剪切的动力学转变过程的逐步延续.北Sinec带使AD3变形处于由坚硬岩石包围的软岩石的狭窄的剪切带中,而在南Ochtina带中AD3变形产生在由里面漂浮着坚硬碳酸盐块的软的岩石柱中.在Ochtina带中,在AD2和AD3阶段由于M2期较低的P-T条件和变形梯度导致了该区有经济价值的滑石矿化不发育.总之,现有的研究结果能用作阿尔卑斯型地体中菱镁矿和滑石找矿的基本标志. | Zoltán NMETH Walter PROCHASKA Martin RADVANEC Martin KOV■IK Ján MADARAS Peter KOD■RA L'ubomír HRA■KO | 2004 | 岩石学报2004，20，4： | 2 |
| 3 | Detailed esophageal function and morphological analysis shows high prevalence of gastroesophageal reflux disease and Barrett’s esophagus in patients with cervical inlet patch显示文摘 | A. Rosztóczy F. Izbéki I. B. Németh S. Dulic K. Vadászi R. Róka K. Gecse T. Gy?keres G. Lázár L. Tiszlavicz T. Wittmann | 2011 | Diseases of the Esophagus2011，，6： | 2 |
| 4 | Capsaicin-sensitive local sensory innervation is involved in pacing-induced preconditioning in rat hearts: role of nitric oxide and CGRP?显示文摘 | P. Ferdinandy Tamás Csont Csaba Csonka Marianna T?r?k Mária Dux József Németh László I. Horváth László Dux Zoltán Szilvássy Gábor Jancsó | 1997 | Naunyn - Schmiedeberg’s Archives of Pharmacology1997，，3： | 1 |
| 5 | Reactions of propaneon supported Mo2C catalysts显示文摘 | Solymosi F Németh R óvári L | 2000 | Journal of Catalysis2000，195，2： | 1 |
| 6 | Aerosol deposition modeling in human airways and alveoli显示文摘 | I. Balásházy I. Németh B. Alf?ldy P.P. Szabó CS. Hegedu?s W. Hofmann J. Pálfalvi I. Fehér Sz. T?r?k | 2000 | Journal of Aerosol Science2000，，： | 1 |
| 7 | A hydrogen-based subsurface microbial community dominated by methanogens显示文摘 | Chapelle F H O'Neill K Bradley P M Methe B A Ciufo S A Knobel L L Lovley D R | 2002 | Nature2002，415，6869： | 1 |
| 8 | The roles of platelet function,thromboxane,blood lipids and nitric oxide in hypertension of children and adolescents显示文摘 | Bereczki C T(u)r S N(e)meth I | 2000 | Prostaglandins Leukot Essent Fatty Acids2000，62，5： | 1 |
| 9 | Fast hyperspectral anoma- ly detection via SVDD显示文摘 | Banerjee A Burlina P Meth R | 2007 | Proceedings 2007 IEEE Inter- national Conference on Image Processing2007，，4： | 1 |
| 10 | Rapid high perform- ance hyperspectral anomaly detection via global support vector data description 显示文摘 | Meth R Banerjee A Burlina P | 2008 | SPIE2008，6967，： | 1 |
| 11 | Network meta-analysis of randomized controlled trials on esophagectomies in esophageal cancer:The superiority of minimally invasive surgery显示文摘BACKGROUND Previous meta-analyses,with many limitations,have described the beneficial nature of minimal invasive procedures.AIM To compare all modalities of esophagectomies to each other from the results of randomized controlled trials(RCTs)in a network meta-analysis(NMA).METHODS We conducted a systematic search of the MEDLINE,EMBASE,Reference Citation Analysis(http://gffzzb1f9d057b5954674sunqwuuk5kxxo6vkb.ffgz.tsg.suse.edu.cn/)and CENTRAL databases to identify RCTs according to the following population,intervention,control,outcome(commonly known as PICO):P:Patients with resectable esophageal cancer;I/C:Transthoracic,transhiatal,minimally invasive(thoracolaparoscopic),hybrid,and robot-assisted esophagectomy;O:Survival,total adverse events,adverse events in subgroups,length of hospital stay,and blood loss.We used the Bayesian approach and the random effects model.We presented the geometry of the network,results with probabilistic statements,estimated intervention effects and their 95% confidence interval(CI),and the surface under the cumulative ranking curve to rank the interventions.RESULTS We included 11 studies in our analysis.We found a significant difference in postoperative pulmonary infection,which favored the minimally invasive intervention compared to transthoracic surgery(risk ratio 0.49;95%CI:0.23 to 0.99).The operation time was significantly shorter for the transhiatal approach compared to transthoracic surgery(mean difference-85 min;95%CI:-150 to-29),hybrid intervention(mean difference-98 min;95%CI:-190 to-9.4),minimally invasive technique(mean difference-130 min;95%CI:-210 to-50),and robot-assisted esophagectomy(mean difference-150 min;95%CI:-240 to-53).Other comparisons did not yield significant differences.CONCLUSION Based on our results,the implication of minimally invasive esophagectomy should be favored. | Lajos Szakó Dávid Németh Nelli Farkas Szabolcs Kiss Réka Zsuzsa Domotor Marie Anne Engh Péter Hegyi Balint Eross András Papp | 2022 | World Journal of Gastroenterology2022，28，30： | 1 |
| 12 | The effect of thermal treatment using vegetable oils on physical and mechanical properties of poplar and robinia wood显示文摘 | NMETH R BAK M TOLVAJ L | 2009 | Pro Ligno2009，5，2： | 1 |
| 13 | Insulin is necessary for the hypertrophic effect of cholecystokinin-octapeptide following acute necrotizing experimental pancreatitis显示文摘AIM: In previous experiments we have demonstrated that by administering low doses of cholecystokinin-octapeptide (CCK-8), the process of regeneration following L-arginine (Arg)-induced pancreatitis is accelerated. In rats that were also diabetic (induced by streptozotocin, STZ), pancreatic regeneration was not observed. The aim of this study was to deduce whether the administration of exogenous insulin could in fact restore the hypertrophic effect of CCK-8 in diabetic-pancreatitic rats.METHODS: Male Wistar rats were used for the experiments.Diabetes mellitus was induced by administering 60 mg/kg body mass of STZ intraperitoneally (i.p.), then, on d 8, pancreatitis was induced by 200 mg/100 g body mass Argi.p. twice at an interval of 1 h. The animals were injected subcutaneously twice daily (at 7 a.m. and 7 p.m.) with 1 μglkg of CCK-8 and/or 2 IU mixed insulin (300 g/L shortaction and 700 g/L intermediate-action insulin) for 14 d after pancreatitis induction. Following this the animals were killed and the serum amylase, glucose and insulin levels as well as the plasma glucagon levels, the pancreatic mass/body mass ratio (pm/bm), the pancreatic contents of DNA, protein, amylase, lipase and trypsinogen were measured. Pancreatic tissue samples were examined by light microscopy on paraffin-embedded sections.RESULTS: In the diabetic-pancreatitic rats treatment with insulin and CCK-8 significantly elevated pw/bm and the pancreatic contents of protein, amylase and lipase vs the rats receiving only CCK-8 treatment. CCK-8 administered in combination with insulin also elevated the number of acinar cells with mitotic activities, whereas CCK-8 alone had no effect on laboratory parameters or the mitotic activities in diabetic-pancreatitic rats.CONCLUSION: Despite the hypertrophic effect of CCK-8 being absent following acute pancreatitis in diabetic-rats,the simultaneous administration of exogenous insulin restored this effect. Our results clearly demonstrate that insulin is necessary for the hypertrophic effect of low-doses of CCK-8 following acute pancreatitis. | Péter Hegyi Zoltán RakonczayJr Réka Sári László Czakó Norbert Farkas Csaba Góg József Németh János Lonovics Tamás Takács | 2004 | World Journal of Gastroenterology2004，10，15： | 1 |
| 14 | Bovine laminitis:Clinical aspects,pathology and pathogenesis with reference to acute equine laminitis显示文摘 | Boosman R Németh F Gruys E | 1991 | Veterinary Quarterly1991，13，3： | 1 |
| 15 | Postprandial gastrointestinal hormone production is different, depending on the type of construction following total gastrectomy显示文摘 | Kalm 6 r K N 6 meth J Kelemen D etal | 2006 | Ann Surg2006，243，4： | 1 |
| 16 | A hybrid algorithms for subpixel detection in hyperspectral imagery 显示文摘 | Brnadwater J Meth R Chellappa R | 2004 | IEEE Interna- tional Geoscience and Remote Sensing Symposium IGARSS2004，3，： | 1 |
| 17 | Effect of cage height on the welfare of growing rabbits显示文摘 | Zoltán Princz István Radnai Edit Biró-Németh Zsolt Matics Zsolt Gerencsér István Nagy Zsolt Szendr? | 2008 | Applied Animal Behaviour Science2008，，1： | 1 |
| 18 | Behaviour of growing rabbits under various housing conditions显示文摘 | Zoltán Princz Antonella Dalle Zotte István Radnai Edit Bíró-Németh Zsolt Matics Zsolt Gerencsér István Nagy Zsolt Szendr? | 2007 | Applied Animal Behaviour Science2007，，3： | 1 |
| 19 | Effects of the angiotensin II ant agonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients wit h chronic renal failure and hypertension 显示文摘 | BNTEN B N**METH R | 1998 | J Am Soc Nephrol1998，9，12： | 1 |
| 20 | The psychrophilic lifestyle as revealed by the genome sequence of Colwellia psychrerythraea 34H throughgenomic and proteomic analyses 显示文摘 | Methe BA Nelson KE Deming JW Momen B Melamud E Zhang XJ Moult J Madupu R Nelson William Dodson RJ Brinkac LM Daugherty SC Durkin AS DeBoy RT Kolonay JF Sullivan SA Zhou LW Davidsen TM Wu M Huston AL Lewis M Weaver B Weidman JF Khouri H Utterback TR Feldblyum TV Fraser CM | 2005 | PNAS2005，102，10： | 1 |
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