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| 1 | Socio-cultural determinants of timely and delayed treatment of Buruli ulcer: implications for disease control显示文摘Introduction:Public health programmes recommend timely medical treatment for Buruli ulcer(BU)infection to prevent pre-ulcer conditions from progressing to ulcers,to minimise surgery,disabilities and the socio-economic impact of BU.Clarifying the role of socio-cultural determinants of timely medical treatment may assist in guiding public health programmes to improve treatment outcomes.This study clarified the role of socio-cultural determinants and health system factors affecting timely medical treatment for BU in an endemic area in Ghana.Methods:A semi-structured explanatory model interview based on the explanatory model interview catalogue(EMIC)was administered to 178 BU-affected persons.Based on research evidence,respondents were classified as timely treatment(use of medical treatment 3 months from awareness of disease)and delayed treatment(medical treatment 3 months after onset of disease and failure to use medical treatment).The outcome variable,timely treatment was analysed with cultural epidemiological variables for categories of distress,perceived causes of BU,outside-help and reasons for medical treatment in logistic regression models.The median time for the onset of symptoms to treatment was computed in days.Qualitative phenomenological analysis of respondents’narratives clarified the meaning,context and dynamic features of the relationship of explanatory variables with timely medical treatment.Results:The median time for initiating treatment was 25 days for pre-ulcers,and 204 days for ulcers.Income loss and use of herbalists showed significantly negative associations with timely treatment.Respondents’use of herbalists was often motivated by the desire for quick recovery in order to continue with work and because herbalists were relatives and easily accessible.However,drinking unclean water was significantly associated with timely treatment and access to health services encouraged timely treatment(OR 8.5,p=0.012).Findings show that health system factors of access are responsible for non-compliance to treatment regimes.Conclusions:Findings highlight the importance of an integrated approach to BU control and management considering the social and economic features that influence delayed treatment and factors that encourage timely medical treatment.This approach should consider periodic screening for early case-detection,collaboration with private practitioners and traditional healers,use of mobile services to improve access,adherence and treatment outcomes. | Mercy M Ackumey Margaret Gyapong Matilda Pappoe Cynthia Kwakye Maclean Mitchell G Weiss | 2012 | Infectious Diseases of Poverty2012，1，1： | 3 |
| 2 | Hypersensitivity of mtDNA-depleted cells to staurosporine-induced apoptosis:roles of Bcl-2 downregulation and cathepsin B显示文摘 | Rommelaere G Michel S Mercy L | | 0，，05： | 1 |
| 3 | Initial disc structural preservation in type A1and A3thoracolumbar fractures显示文摘 | Loriaut P Mercy G Moreau PE | 2015 | Orthop Traumatol Surg Res2015，101，7： | 1 |
| 4 | Impact of radiation models in CFD simulations of steam cracking furnaces 显示文摘 | HABIBI A MERCI B HEYNDERICKX G J | 2007 | Computers & Chemical Engineering2007，31，11： | 1 |
| 5 | Two mRNA species encoding calcium-dependent protein kinase are differentially expressed in sexual organs of Maechantia polymorpha through alternative splicing显示文摘 | Berkowitz G Zhang X Mercie R etal | 2000 | Plant Cell Physiol2000，41，6： | 1 |
| 6 | CFDsimulations of steam cracking furnaces using detailedcombustion mechanisms显示文摘 | Stefanidis G D Merci B Heynderickx G J | 2006 | Computers and ChemicalEngineering2006，30，： | 1 |
| 7 | CFD simulations of steam cracking furnaces using detailed combustion mechanisms显示文摘 | Stcfanidis G D Merci B Hcyndcfickx G J | 2006 | Computcrs & Chemical Engineering2006，30，4： | 1 |
| 8 | Impact of radiationmodels in CFD simulations of steam cracking furnaces显示文摘 | Habibi A Merci B Heynderickx G J | 2007 | Computers and Chemical Engineering2007，31，： | 1 |
| 9 | Tidal breathing flowvolume loops in bronchiolitis in infancy: the effect of albuterol显示文摘 | Totapally BR De merci C Zurei Kat G | 2002 | Crit Care2002，6，2： | 1 |
| 10 | CFD simulations of steam cracking furnaces using detailed combustion mechanisms显示文摘 | Stefanidis G D Merci B Heynderickx G J | 2006 | Computers and Chemical Engineering2006，30，4： | 1 |
| 11 | A review of the value of MRI signs in low back pain显示文摘 | Ract I Meadeb JM Mercy G | 2015 | Diagnostic and Interventional Imaging2015，96，3： | 1 |
| 12 | Study of nickel catalysts supported on silica of low surface area and prepared by reduction of nickel acetate in aquenous hydrazine显示文摘 | A G Boudjahem S Monteverdi M Mercy | 2004 | Journal of Catalysis2004，221，： | 1 |
| 13 | CFD simulations of steam cracking furnaces using detailed combustion mechanisms 显示文摘 | STEFANIDIS G D MERCI B HEYNDERICKX G J MARIN G B | 2006 | Comput Chem Eng2006，30，4： | 1 |
| 14 | Morphological studies on the oocytes of the blind catfish Horaglanis krishnai Menon显示文摘 | Mercy T V A Padmanabhan K G Pillai N K | 1982 | Zool Anz1982，209，： | 1 |
| 15 | Impact of radiation model in CFD simulation of steam cracking furnaces显示文摘 | Habibi A Merci B Heynderickx G J | 2007 | Computer and Chemical Engineering2007，31，11： | 1 |
| 16 | Morphological studies on the oocytes of the blind eatfish Horaglanis krishnai Menon显示文摘 | MERCY T V A PADMANABHAN K G PILLAI N K | 1982 | Zool Anz1982，209，： | 1 |
| 17 | Impact of radiationmodels in CFD simulations of steam cracking furnaces显示文摘 | A Habibi B Merci G J Heynderickx | 2007 | Computers and Chemical Engineering2007，31，： | 1 |
| 18 | Impact of radiation models in CFD simulations of steam cracking furnaces显示文摘 | Habibi A Merci B Heyndefickx G J | 2007 | Computers and Chemical Engineering2007，31，11： | 1 |
| 19 | CFD simulations of steam cracking furances using detailed combustion mechanisms显示文摘 | Stefanidis G D Merci B Heynderickx G J | 2006 | Computer Chemical Engineer2006，30，： | 1 |
| 20 | Impact of radiation model in CFD simulation of steam cracking furnaces显示文摘 | AHabib B Merci G J Heynderickx | 2007 | Computer and Chemical Engineering2007，31，： | 1 |
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