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| 1 | TGF-β1基因多态性与肝炎后肝纤维化的相关性研究显示文摘目的:探讨TGF-β1基因多态性与肝炎后肝纤维化的关系。方法:以实时荧光PCR结合熔点曲线分析,建立可高通量检测TGF-β1编码区3个单核苷酸多态性(SNPs)位点的LightCycler方法,这3个位点分别为Leu10Pro(T>C)、Arg25Pro(G>C)、Thr263Ile(C>T),并对亚洲人群中HBV感染导致的肝纤维化患者(90例)及高加索人群中HCV感染导致的肝纤维化患者(210例)进行SNP分析,并分别与104例亚洲人群和50例高加索人群正常献血员进行比较。结果:亚洲人群中病患组与正常对照组TGF-β1编码区第25、263位氨基酸皆无基因多态性,与高加索人群的检测结果有显著差异;而亚洲人群第10位氨基酸基因多态性出现频率相对较高,病患组(T/C=0.444/0.556)较正常对照组(T/C=0.514/0.486)突变频率稍高,但无显著差异。在高加索人群HCV感染导致的肝纤维化患者中第10、25位氨基酸基因多态性出现的频率与肝纤维化发展程度(average METAVIR-Score)密切相关。结论:提示TGF-β1基因多态性与高加索人群肝炎后肝纤维化的发生具有重要相关性;与亚洲人群肝炎后肝纤维化发生的相关性有待进一步研究。 | 王皓 杨再兴 高春芳 万漠彬 王晓今 Senait Mengsteab Axel M.Gressner Ralf Weiskirchen | 2004 | 第二军医大学学报2004，25，12： | 5 |
| 2 | Exclosures restored the density and root colonization of arbuscular mycorrhizal fungi in Tigray, Northern Ethiopia显示文摘Introduction:Exclusion of grazing animals and tree plantations were among the methods used for the restoration of degraded lands in tropical semiarid areas.Exclosures can foster secondary forest succession by improving soil conditions and modifying microclimate for understory growth.This paper compared the arbuscular mycorrhizal fungi(AMF)spore density,root colonization of woody plants and soil chemical properties under exclosure with increasing age,and grazing land at different slope positions.Methods:The study was conducted in northern Ethiopia from 12 exclosure sites paired each with adjacent grazing land in total from 24 sites with four treatments replicated three times.In the entire study,216 plots were examined of which 108 were in exclosures and 108 in communal grazing lands.There were four age classes and three slope positions in each of the land uses.Composite soil and root samples were collected using nested plots measuring 100m2 from four sides of 1763 plants for spore enumeration and root colonization.Soils for chemical properties were collected from the four corners and center of 5 m×5 m plots.Results:All the 61 woody plant species that belong to 41 families were colonized by AMF.Spore density and root colonization were significantly higher in exclosures as compared to grazing land and increased with increasing ages of exclosures.Foot slope had significantly higher spore density and root colonization than middle and upper slopes.Soil chemical properties were significantly higher in the exclosure,oldest age of exclosure,and foot slope position(except P).AMF spore density and root colonization were significantly positively correlated with soil chemical properties.Conclusions:Exclosures are helpful to restore the AMF spore density and root colonization of woody species and soil fertility. | Emiru Birhane Kide Mogos Gebremedihin Tewodros Tadesse Mengsteab Hailemariam Negasi Solomon | 2017 | Ecological Processes2017，6，1： | 2 |
| 3 | Analysis of polymorphic TGFB1 codons 10,25,and 263 in a German patient group with non-syndromic cleft lip,alveolus,and palate compared with healthy adults显示文摘 | Stoll C Mengsteab S Stoll D | | 0，，05： | 1 |
| 4 | Analysis of the transforming growth factor-β1 (TGF-β1) codon 25 gene polymorphism by LightCycler-analysis in patients with chronic hepatitis C infection显示文摘 | Carmen G. Tag Senait Mengsteab Claus Hellerbrand Frank Lammert Axel M. Gressner Ralf Weiskirchen | 2003 | Cytokine2003，，5： | 1 |
| 5 | Analysis of the transforming growth factor-beta1 (TGF-beta1) codon 25 gene polymorphism by Light Cycler-analysis in patients with chronic hepatitis C infection显示文摘 | Tag CG Mengsteab S Hellerbrand C | 2003 | Cytokine2003，24，5： | 1 |
| 6 | Variations in soil properties and native woody plant species abundance under Prosopis juliflora invasion in Afar grazing lands, Ethiopia显示文摘Introduction:Pastoralism and agro-pastoralism are the major modes of life in arid and semi-arid rangelands.However,rangeland quality and quantity are rapidly deteriorating due to a number of natural and human-induced factors,one of which is bush encroachment.Little is known on how bush encroachment affects the ecosystem functions and services expressed in terms of the native vegetation composition and structure,status of the soil seed bank,soil chemical and physical properties,and the abundance of mycorrhiza spores.Methods:We assessed woody species in 64 plots distributed across four levels of Prosopis juliflora invasion(high,medium,low,and none)at two sites,Amibara and Gewane,in the Afar Region,Ethiopia.We collected composite soil samples to investigate the soil seed bank,mycorrhizal associations,and spore abundance.Results:Plant biodiversity was generally low,with eight and four woody species in Gewane and Amibara,respectively.Prosopis juliflora was dominant in highly,moderately,and lowly invaded areas while Acacia senegal dominated the non-invaded areas.The average number of P.juliflora individuals ranged from 3/ha at non-invaded areas in Gewane to 4200/ha at highly invaded areas in Amibara while the total individual number of native woody species ranged from 0 to 88/ha at highly and lowly invaded areas,respectively.The population structure of trees/shrubs in all invasion areas showed an inverted J-shaped distribution,characterized by a high abundance of small individuals.Prosopis juliflora invasion was associated with high soil OC,Na,Ca,P,bulk density,and moisture content.Herbaceous seed numbers and species richness were highest in the moderately and highly invaded areas.All sampled tree species were associated with mycorrhiza but the percentage of root length colonization by different arbuscular mycorrhizal fungus structures varied significantly(p<0.05)across invasion categories and sites.Conclusions:Our results revealed that although P.juliflora invasion negatively impacted the availability of native woody livestock forage species,it had a positive effect on most soil physical and chemical properties.Such variable effects call out for sustainable management practices when invaded areas are restored. | Abeje Eshete Anna C.Treydte Mengsteab Hailemariam Negasi Solomon Tatek Dejene Zewdu Yilma Emiru Birhane | 2020 | Ecological Processes2020，9，1： | 1 |
| 7 | Analysis of polymorphic TGF-β 1 codons 10,25,and 263 in a German patient group with non-syndromic cleft lip,alveolus,and palate compared with healthy adults显示文摘 | Stoll C Mengsteab S Stoll D | 2004 | BMC Med Genet2004，22，1： | 1 |
| 8 | Analysis of the transforming growth factor-β1 (TGF-β1) codon 25 gene polymorphism by LightCycler-analysis in patients with hepatitis C infection显示文摘 | Mengsteab S Hellerbrand C | 2003 | Cytokine2003，24，5： | 1 |
| 9 | Streamlining Government Financing Programs for SMEs in the Sub-Saharan Africa: The Case of Botswana显示文摘 | Mengsteab Tesfayohannes | 2012 | China-USA Business Review2012，11，2： | 0 |
| 10 | Source of mycorrhizal inoculum influences growth of Faidherbia albida seedlings显示文摘Poor land use management and practice inhibit the growth and establishment of tree seedlings in dryland areas.We assessed arbuscular mycorrhizal fungi(AM)status of Faidherbia albida(Del.)A.Chev.trees grown on different land uses.We quantified the growth and nutrient uptake of F.albida seedlings inoculated with AM from different sources.These efforts were based on soil and fine root samples from the rhizosphere soils of F.albida trees.AM root colonization was determined using the gridline intersect method.Spores were extracted by the wet sieving and decanting method and identified to genus level.The seedling experiment had a completely randomized onefactorial design with four treatments and five replications.Faidherbida albida seedlings were grown in a greenhouse.All in situ F.albida trees were colonized by AM fungi.AM root colonization of F.albida trees was significantly higher(P<0.0086)in area exclosures than on lands used for grazing or cultivation.Spore abundance was significantly higher(P<0.0014)in area exclosures followed by cultivated land and grazing land.Glomus was the dominant genus in all land-uses.AM-inoculated F.albida seedlings grew better(P<0.05)than non-inoculated controls.Seedlings inoculated with AM from area exclosure had significantly(P<0.05)higher growth and nutrient uptake than those inoculated with AM from grazing and cultivated land.This emphasizes the importance of the native soil AM potential for better establishment of seedlings to achieve optimum plant growth improvement and assist in rehabilitation of degraded arid lands. | Emiru Birhane Mengsteab Hailemariam Girmay Gebresamuel Tesfay Araya Kiros Meles Hadgu Lindsey Norgrove | 2020 | Journal of Forestry Research2020，31，1： | 0 |
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