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| 1 | New research trends on high-precision time transfer technology显示文摘High-precision time transfer plays an important role in the areas of fundamental research and applications. Accompanying w ith the remarkable improvements in the ability of generating and measuring high-accuracy time-frequency signal,seeking for new time-transfer techniques betw een distant clocks w ith much further improved accuracy attracts attentions w orld-w idely. The time-transfer technique based on optical pulses has the highest precision presently,and the further improvement in the accuracy is heavily dependent on the time-domain properties of the pulse as w ell as the sensitivity of the applied measurement on the exchanged pulse. The application of optical frequency comb in time transfer for a precision up to femtosecond level are currently the focus of much interest,and has recently achieved many breakthroughs. Further investigations show that,utilizing quantum techniques,i.e. quantum measurement technique and quantum optical pulse source,can lead to a new limit on the measured timing information. Furthermore,it can be immune from atmospheric parameters,such as pressure,temperature,humidity and so on.Such quantum improvements on time-transfer have a bright prospect in the future applications requiring extremely high-accuracy timing and ranging. The potential achievements w ill form a technical basis for the future realization of sub-femtosecond time transfer system. | DONG Ruifang QUAN Run'ai HOU Feiyan WANG Shaofeng XIANG Xiao ZHOU Conghua WANG Mengmeng LIU Tao ZHANG Shou'gang | 2015 | Instrumentation2015,2,4: | 5 |
| 2 | OsGCD1,a novel player in rice intine construction显示文摘In angiosperms,pollen development is an intricate indispensable process for successful sexual reproduction,which involves accurately and tightly controlled regulations and requires numerous genes expressed in both sporophytic and gametophytic tissues of the anther(McCormick,2004).Understanding the molecular mechanism underlying pollen development is of great significance for the construction of male sterile lines and crop breeding.However,many critical issues concerning pollen development still need to be elucidated.Recently,targeted editing of pollen development-related genes mediated by CRISPR/Cas9 system has provided powerful tools to facilitate the relevant studies in crops to figure out these issues(Li et al., 2016,2017). | Xiaorong Huang Mengmeng Run Meng-Xiang Sun | 2019 | Journal of Genetics and Genomics2019,46,7: | 3 |
| 3 | A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease显示文摘Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson s disease,but the regulato ry mechanism remains elusive.Prohibitin-2(PHB2)is a newly discove red autophagy receptor in the mitochondrial inner membrane,and its role in Parkinson’s disease remains unclear.Protein kinase R(PKR)-like endoplasmic reticulum kinase(PERK)is a factor that regulates cell fate during endoplasmic reticulum stress.Parkin is regulated by PERK and is a target of the unfolded protein response.It is unclear whether PERK regulates PHB2-mediated mitophagy thro ugh Parkin.In this study,we established a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced mouse model of Parkinson’s disease.We used adeno-associated virus to knockdown PHB2 expression.Our res ults showed that loss of dopaminergic neurons and motor deficits were aggravated in the MPTP-induced mouse model of Parkinson’s disease.Ove rexpression of PHB2 inhibited these abnormalities.We also established a 1-methyl-4-phenylpyridine(MPP+)-induced SH-SY5Y cell model of Parkinson’s disease.We found that ove rexpression of Parkin increased co-localization of PHB2 and microtubule-associated protein 1 light chain 3,and promoted mitophagy.In addition,MPP+regulated Parkin involvement in PHB2-mediated mitophagy through phosphorylation of PERK.These findings suggest that PHB2 participates in the development of Parkinson’s disease by intera cting with endoplasmic reticulum stress and Parkin. | Yongjiang Zhang Shiyi Yin Run Song Xiaoyi Lai Mengmeng Shen Jiannan Wu Junqiang Yan | 2024 | Neural Regeneration Research2024,19,8: | 0 |
| 4 | Morphology modulation of artificial muscles by thermodynamic-twist coupling显示文摘Human muscles can grow and change their length with body development;therefore,artificial muscles that modulate their morphology according to changing needs are needed.In this paper,we report a strategy to transform an artificial muscle into a new muscle with a different morphology by thermodynamic-twist coupling,and illustrate its structural evolution during actuation.The muscle length can be continuously modulated over a large temperature range,and actuation occurs by continuously changing the temperature.This strategy is applicable to different actuation modes,including tensile elongation,tensile contraction and torsional rotation.This is realized by twist insertion into a fibre to produce torsional stress.Fibre anne aling causes partial thermodynamic relaxation of the spiral molecular chains,which serves as internal tethering and inhibits fibre twist release,thus producing a self-supporting artificial muscle that actuates under heating.At a sufficiently high temperature,further relaxation of the spiral molecular chains occurs,resulting in a new mus cle with a different length.A structural study provides an understanding of the thermo dynamic-twist coupling.This work provides a new design strategy for intelligent materials. | Xiaoyu Hu Jiatian Li Sitong Li Guanghao Zhang Run Wang Zhongsheng Liu Mengmeng Chen Wenqian He Kaiqing Yu Wenzhong Zhai Weiqiang Zhao Abdul Qadeer Khan Shaoli Fang Ray HBaughman Xiang Zhou Zunfeng Liu | 2023 | National Science Review2023,10,1: | 0 |
| 5 | Size-refinement enhanced flexibility and electrochemical performance of MXene electrodes for flexible waterproof supercapacitors显示文摘Increasing mechanical flexibility without sacrificing electrochemical performance of the electrode material is highly desired in the design of flexible electrochemical energy storage devices.In metal-related materials science,decreasing the grain size introduces more grain boundaries;this stops dislocations and crack propagation under deformation,and results in increased strength and toughness.However,such a size refinement effect has not been considered in the mechanical properties,particle stacking,wetting,and electrochemical performances of flexible supercapacitor electrodes.In this paper,MXene was used as an electrode material to study the size refinement effect of flexible supercapacitors.Size refinement improved the strength and toughness of the MXene electrodes,and this resulted in increased flexibility.Finite elemental analysis provided a theoretical understanding of size refinement-increased flexibility.Moreover,the size refinement also improved the specific surface area,electric conductance,ion transportation,and water wetting properties of the electrode,and the size refinement provided highly increased energy density and power density of the MXene supercapacitors.A highly flexible,water-proof supercapacitor was fabricated using size-refined MXene.The current study provides a new viewpoint for designing tough and flexible energy storage electrodes.The size refinement effect may also be applicable for metal ion batteries and electronic and photo devices composed of MXene and other nanoparticles. | Jinkun Sun Yingjian Liu Jiayi Huang Jiatian Li Mengmeng Chen Xiaoyu Hu Yatao Liu Run Wang Yanan Shen Jingjing Li Xuecheng Chen Dong Qian Baigang An Zunfeng Liu | 2021 | Journal of Energy Chemistry2021,30,12: | 0 |