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| 1 | Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation. | Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 7 |
| 2 | Transient receptor potential channels in the kidney:calcium signaling,transport and beyond显示文摘 | Mene P | 2006 | J Nephrol2006，19，1： | 1 |
| 3 | Physiology of the mesangial cell 显示文摘 | Mene P Simonson MS Dunn MJ | 1989 | Physiol Rev1989，69，4： | 1 |
| 4 | ThromboxaneA2 , prostaglandins and mesangial cell proliferation 显示文摘 | Mene P Pugliese F Agostino AD | 1992 | Kidney Int1992，241，： | 1 |
| 5 | Interleukin-1 generation transmembrane signal from phospholipids through novel pathways in cultured rat mesangial cell显示文摘 | Kester M Simonson MS Mene P | 1989 | J Clin Invest1989，83，2： | 1 |
| 6 | Clinical potential of advanced glycation end-product inhibitors in diabetes mellitus显示文摘 | Mene P Festuccia F Pugliese F | 2003 | American Journal of Cardiovascular Drugs2003，3，5： | 1 |
| 7 | Mesangial cell cultures显示文摘 | Mene P | 2001 | J Nephrol2001，14，3： | 1 |
| 8 | Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring显示文摘 | Alonso-Magdalena P Vieira E Soriano S Menes L Burks D Quesada I | 2010 | Environ Health Perspect2010，118，9： | 1 |
| 9 | Endothelin stimulates phos-pholipase C,Na+/H+ exchange,c-fos expression,and mitogenesis in ratmesangial cells显示文摘 | Simonson MS Wann S Mene P | | 0，，： | 1 |
| 10 | Mesangial cell cultures显示文摘 | Mene P | | 0，，03： | 1 |
| 11 | Mitogenic signals for thrombin in mesangial cells:Regulation of phospholipase C and PDGF genes显示文摘 | Shultz P J Knauss T C Mene P | 1989 | Am J Physiol1989，257，32： | 1 |
| 12 | A technique to excise the deseemet membrane from a recipient cornea (desceme to rhexis) 显示文摘 | Menes G R Wijdh R H Nieuwendaal C P | 2004 | Cornea2004，23，3： | 1 |
| 13 | Effects of Advanced Glycation End Products on Cytosolic Ca^2+ Sighting of Cultured Human Mesangial Cells 显示文摘 | Mene P Pascale C Teti A | 1999 | J Am Soc Nephrol1999，10，7： | 1 |
| 14 | Apoptosis: potential role in renal di-seases显示文摘 | MEne P Amore A | 1998 | Nephrol Dialysis Transplant1998，13，8： | 1 |
| 15 | Endothelin stimulates phospholipase C、Na+/H+ exchange 、c-fos expression and mitogenesis in rat mesangial cells显示文摘 | Simonson MS Wann S Mene P | 1989 | J Clin Invest1989，83，2： | 1 |
| 16 | Binary System, Ethanol Ethylene Glycol 显示文摘 | MENE P S | 1978 | Indian Chem Eng1978，20，： | 1 |
| 17 | Influence of particle abrasion or hydrofluoric acid etching on lithium disilicate flexural strength显示文摘 | Menees T Lawson N Beck P | 2014 | J Prosthet Dent2014，112，5： | 1 |
| 18 | Diabetic nephropathy and advanced glycation end products 显示文摘 | Festuccia F | 2001 | Contrib Nephrol2001，131，2： | 1 |
| 19 | Role of uric acid in hypertension and in the progression of chronic renal disease显示文摘 | Barberi S Mene P | | 0，，01： | 1 |
| 20 | Physiology of the mesangial cell显示文摘 | Mene P Simonson MS Dunn MJ | 1989 | Physiol Rev1989，69，4： | 1 |
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