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| 1 | Predictors of suboptimal bowel preparation in asymptomatic patients undergoing average-risk screening colonoscopy显示文摘AIM To identify risk factors for a suboptimal preparation among a population undergoing screening or surveillance colonoscopy.METHODS Retrospective review of the University of Michigan and Veteran's Administration(VA) Hospital records from 2009 to identify patients age 50 and older who underwent screening or surveillance procedure and had resection of polyps less than 1 cm in size and no more than 2 polyps. Patients with inflammatory bowel disease or a family history of colorectal cancer were excluded. Suboptimal procedures were defined as procedure preparations categorized as fair, poor or inadequate by the endoscopist. Multivariable logistic regression was used to identify predictors of suboptimal preparation.RESULTS Of 4427 colonoscopies reviewed, 2401 met our inclusion criteria and were analyzed. Of our population, 16% had a suboptimal preparation. African Americans were 70% more likely to have a suboptimal preparation(95%CI: 1.2-2.4). Univariable analysis revealed that narcotic and tricyclic antidepressants(TCA) use, diabetes, prep type, site(VA vs non-VA), and presence of a gastroenterology(GI) fellow were associated with suboptimal prep quality. In a multivariable model controlling for gender, age, ethnicity, procedure site and presence of a GI fellow, diabetes [odds ratio(OR) = 2.3; 95%CI: 1.6-3.2], TCA use(OR = 2.5; 95%CI: 1.3-4.9), narcotic use(OR = 1.7; 95%CI: 1.2-2.5) and Miralax-Gatorade prep vs 4L polyethylene glycol 3350(OR = 0.6; 95%CI: 0.4-0.9) were associated with a suboptimal prep quality. CONCLUSION Diabetes, narcotics use and TCA use were identified as predictors of poor preparation in screening colonoscopies while Miralax-Gatorade preps were associated with better bowel preparation. | Shail M Govani Eric E Elliott Stacy B Menees Stephanie L Judd Sameer D Saini Constantinos P Anastassiades Annette L Urganus Suzanna J Boyce Philip S Schoenfeld | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，17： | 7 |
| 2 | Split-dose bowel preparation improves adequacy of bowel preparation and gastroenterologists' adherence to National Colorectal Cancer Screening and Surveillance Guidelines显示文摘AIM To quantify the impact of split-dose regimen on endoscopists' compliance with guideline recommendations for timing of repeat colonoscopy in patients with normal colonoscopy or 1-2 small polyps(< 10 mm).METHODS A retrospective chart review of all endoscopy reports was undertaken in average-risk individuals > 50 years old with a normal screening colonoscopy and 1-2 small polyps. Data were abstracted from two time periods, pre and post-split-dose bowel preparation institution. Main outcome measurements were recommendation for timing of repeat colonoscopy and bowel preparation quality. Bivariate analysis by χ~2 tests and Student's t-tests were performed to assess differences between the two cohorts. Multivariable logistic regression was used with guideline consistent recommendations as the dependent variables and an indicator for 2011 cohort as the primary predictor. RESULTS Four thousand two hundred and twenty-five patients were included in the study; 47.0%(1987) prior to the institution of split dose bowel preparation, and 53.0%(2238) after the institution of split dose bowel preparation. Overall, 82.2%(n = 3472) of the colonoscopies were compliant with guideline recommendations, with a small but significantly increased compliance rate in year 2011(83.7%) compared to year 2009(80.4%, P = 0.005), corresponding to an unadjusted odds ratio of 1.25(95%CI: 1.07-1.47; P = 0.005). Colonoscopies with either 'Adequate' or 'Excellent' had increased from 30.6% in year 2009 to 39.6% in year 2011(P < 0.001). However, there was no significant difference in poor/inadequate category of bowel preparation as there was a mild increase from 4.6% in year 2009 to 5.1% in year 2011(P = 0.50). CONCLUSION Split-dose bowel regimen increases endoscopists' compliance to guidelines in average-risk patients with normal colonoscopy or 1-2 small polyps. | Stacy Bartnik Menees H Myra Kim Philip Schoenfeld | 2018 | World Journal of Gastroenterology2018，24，6： | 4 |
| 3 | A survey of ampullectomy practices显示文摘AIM:To investigate the endoscopic ampullectomy practices of expert biliary endoscopists.METHODS:An anonymous survey was mailed to 79 expert biliary endoscopists to assess ampullectomy practices.RESULTS:Forty six(58%) biliary endoscopists returned the questionnaire.Of these, 63% were in academia and in practice for an average of 16.4 years(± 8.6).Endoscopists performed an average of 1.1(± 0.8) ampullectomies per month.Prior to ampullectomy, endoscopic ultrasound was'always'utilized by 67% of respondents vs'sometimes'in 31% of respondents.Empiric biliary sphincterotomy was not utilized uniformly, only 26%'always'and 37%'sometimes'performed it prior to resection.Fifty three percent reported'never'performing empiric pancreatic sphincterotomy prior to ampullectomy.Practitioners with high endoscopic retrograde cholangiopancreatography volumes were the most likely to perform a pancreatic sphincterotomy(OR = 10.9;P = 0.09).Participants overwhelmingly favored'always'placing a prophylactic pancreatic stent, with 86% placing it after ampullectomy rather than prior to resection(23%).Argon plasma coagulation was the favored adjunct modality(83%) for removal of residual adenomatous tissue.Practitioners uniformly(100%) preferred follow-up examination to be within 6 mo post-ampullectomy.CONCLUSION:Among biliary experts, there is less variation in ampullectomy practices than is reflected in the literature. | Stacy B Menees Philip Schoenfeld Hyungjin Myra Kim Grace H Elta | 2009 | World Journal of Gastroenterology2009，15，28： | 2 |
| 4 | Early debridement and delayed primary vascularized cover in forearm electrical burns: A prospective study显示文摘AIM To look into the management options of early debridement of the wound, followed by vascularized cover to bring in fresh blood supply to remaining tissue in electrical burns. METHODS A total of 16 consecutive patients sustaining full thickness forearm burns over a period of one year were included in the study group. Debridement was undertaken within 48 h in 13 patients. Three patients were taken for debridement after 48 h. Debridement was repeated within 2-4 d after daily wound assessment and need for further debridement. RESULTS On an average two debridements(range 1-4) was required in our patients for the wound to be ready for definitive cover. Interval between each debridement ranged from 2-18 d. Fourteen patients were provided vascularized cover after final debridement(6 free flaps, 8 pedicled flaps). Functional assessment of gross hand function done at 6 wk, 2 mo, 3 mo and 6 mo follow-up. CONCLUSION High-tension electrical burns lead to significant morbi-dity. These injuries are best managed by early decompression followed by multiple serial debridements. The ideal timing of free flap coverage needs further investigation. | Aniruddh Mene Gautam Biswas Atul Parashar Anish Bhattacharya | 2016 | World Journal of Critical Care Medicine2016，5，4： | 2 |
| 5 | Laparoscopy:searching for the proper insufflation gas显示文摘 | Menes T Spivak H | 2000 | Surg Endosc2000，14，11： | 1 |
| 6 | Transient receptor potential channels in the kidney:calcium signaling,transport and beyond显示文摘 | Mene P | 2006 | J Nephrol2006，19，1： | 1 |
| 7 | Biochemical characterization of a FAD dependent monooxygenase, ornithine hydroxylase from Pseudomonas aeruginosa, suggests a novel reaction mechanism显示文摘 | Meneely KM Lamb AL | 2007 | Biochemistry2007，46，11： | 1 |
| 8 | Risk factors of treatment failure in community acquired pneumonia: implications for disease outcome显示文摘 | Mene'ndez R Torres A Zalacat'n R | 2004 | Thorax2004，59，11： | 1 |
| 9 | Physiology of the mesangial cell 显示文摘 | Mene P Simonson MS Dunn MJ | 1989 | Physiol Rev1989，69，4： | 1 |
| 10 | Factors associated withquality of life among women with fecal incontinence 显示文摘 | SMITH TM MENEES SB XU X | 2013 | IntUrogynecol J2013，24，3： | 1 |
| 11 | Upgrading or polarization? Occupational change in britain, germany, spain and switzerland, 1990-2008显示文摘 | OESCH D MENES J R | 2010 | Socio-Economic Review2010，29，1： | 1 |
| 12 | Spatial and functional correlation between diamine oxidase and per oxidase activities and their dependence upon de-etiolation and wounding in chick-pea stems显示文摘 | MENES F FEDERICO R | 1990 | Planta1990，182，： | 1 |
| 13 | ThromboxaneA2 , prostaglandins and mesangial cell proliferation 显示文摘 | Mene P Pugliese F Agostino AD | 1992 | Kidney Int1992，241，： | 1 |
| 14 | Pathogenesis and current management of gastrooesophageal-reflux-related asthma显示文摘 | Menes T Lelcuk S Spivak H | | 0，，08： | 1 |
| 15 | The independent contribution of diabetic neuropathy and vaseulopathy in foot ulceration 显示文摘 | Meneely MJ Boyko E J Ahroni JH | 1995 | Diabetes Care1995，18，： | 1 |
| 16 | Interleukin-1 generation transmembrane signal from phospholipids through novel pathways in cultured rat mesangial cell显示文摘 | Kester M Simonson MS Mene P | 1989 | J Clin Invest1989，83，2： | 1 |
| 17 | Clinical potential of advanced glycation end-product inhibitors in diabetes mellitus显示文摘 | Mene P Festuccia F Pugliese F | 2003 | American Journal of Cardiovascular Drugs2003，3，5： | 1 |
| 18 | Squamous papilloma of the esophagus:long-term follw-up显示文摘 | Mosca S Menes G Monaco R | | 0，，08： | 1 |
| 19 | Therapeutic efficacy of ozone in patients with diabetic foot 显示文摘 | Marttnez-Sanchez G1 Al-Dalain SM Mene ndez S | 2005 | Eur J Pharmacol2005，523，13： | 1 |
| 20 | Mesangial cell cultures显示文摘 | Mene P | 2001 | J Nephrol2001，14，3： | 1 |
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