|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Type 2 diabetes mellitus and CA 19-9 levels显示文摘AIM:To prospectively investigate serum CA 19-9 levels in type 2 diabetic patients in comparison with age-and gender-matched control subjects. METHODS:We recorded duration of diabetes and examined fasting glucose levels,HbA1c levels and serum CA 19-9 levels in 76 type 2 diabetic patients and 76 controls.Abdominal CT was performed in order to eliminate abdominal malignancy in the diabetic and control groups. RESULTS:The average CA 19-9 level was 46.0±22.4 U/mL for diabetic patients whereas it was 9.97±7.1 U/mL for the control group(P<0.001).Regression analysis showed a positive correlation between diabetes and CA 19-9 independent from age,gender,glucose level and HbA1c level(t=8.8,P<001).Two of the diabetic patients were excluded from the study because of abdominal malignancy shown by CT at the initial evaluation.For all patients,abdominal CT showed no pancreatic abnormalities. CONCLUSION:CA 19-9 is a tumor-associated antigen, which is elevated in pancreatic,upper gastrointestinal tract,ovarian hepatocellular,and colorectal cancers,as well as in inflammatory conditions of the hepatobiliary system,biliary obstruction and in thyroid diseases. Diabetes has been claimed to be a risk factor for pancreatic cancer,which is increasing its incidence and has one of the lowest survival rates of all cancers.CA 19-9 is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes.We propose that a higher cut- off value of CA 19-9 should be used in diabetics to differentiate benign and malignant pancreatic disease, and subtle elevations of CA 19-9 in diabetics should be considered as the indication of exocrine pancreatic dysfunction. | Oya Uygur-Bayramicli Resat Dabak Ekrem Orbay Can Dolapclo■lu Mehmet Sargin Gamze Kilico■lu Yüksel Güleryüzlü Alpaslan Mayada■li | 2007 | World Journal of Gastroenterology2007，13，40： | 63 |
| 2 | 孤独症谱系障碍的风险因素与预后联系:有恢复的证据吗?显示文摘孤独症谱系障碍(本文指孤独症)对不同的个体产生的影响不同,是几种重叠的神经发育疾病之一。这种变异性是生物学和非生物学风险因素之间动态相互作用的结果,随着时间的推移,会导致个体之间的分化差异增加。尽管分化一直持续到成年,但婴儿期是大脑和行为迅速发展,以及孤独症症状和体征最初出现的时期。本文将详述导致孤独症和重叠神经发育疾病的机制及进展。研究还绘制了某些风险人群(即孤独症儿童的同胞弟妹和/或因发育问题而转诊的婴儿)的大脑和行为发展轨迹,有助于在婴儿出现症状之前提高早期识别和确定针对性干预措施的可行性。然而,对于该病我们仍然存在关键性的知识鸿沟,例如尚未发现可能减轻风险影响的保护因素(生物或环境学方面的)。此外,需要进一步研究风险因素和结局之间联系的动态机制,包括恢复的过程,这可能解释了为什么一些有孤独症风险的个体取得了比预期更好的结果。弥合这些知识差距,将有助于找到早期识别和干预的手段,反映从风险到结果的动态发展路径。 | Mayada Elsabbagh 陈静(译) 何燕玲(校) | 2020 | 英国医学杂志中文版2020，23，8： | 3 |
| 3 | Video head impulse test (vHIT) in migraine dizziness显示文摘Background and objective: Migraine is an extremely prevalent primary headache disorder that frequently associates parallel symptoms such as dizziness, tinnitus and hearing loss. Our aim is to investigate differences in video head impulse(vHIT) results with patients suffering from vestibular migraine(VM) and healthy people, taking into consideration mean values of vestibule ocular reflex(VOR) gain, occurrence of the compensatory saccades latency and amplitude. According to the results, determine the usefulness of vHIT in vestibular migraine diagnostics.Methods: A total number of 120 subjects were enrolled in the study, 80 of them were vestibular migraine patients(VM),while the other 40 were a control group of age matched healthy subjects. History was taking during the evaluation;videonystagmography and the video head impulse test were done.Results: The rate of saccades is much more higher in the VM group compared to the healthy subjects group, only 7.5% of the VM group showed a low VOR gain with compensatory saccades denoting a vestibular deficit.Conclusion: The refixation saccades are an important sign that could underlie different vestibular problems. vHIT result can contribute to the completion of full mosaic of vestibular migraine diagnostics. | Mayada ElSherif Mohamed Ihab Reda Horeya Saadallah Mona Mourad | 2018 | Journal of Otology2018，13，2： | 3 |
| 4 | Oxygen isotope fractionation divalent metal carbonates显示文摘 | O'Neil J R Clayton R N Mayada T K | 1969 | Chemistry Geophysics1969，51，： | 1 |
| 5 | Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis显示文摘 | Vielhauer V Stavrakis G Mayadas T N | 2005 | Journal of Clinical Investigation2005，115，5： | 1 |
| 6 | 显示文摘 | Mayadas A F Shatzkes M | 1970 | Phys Rev B1970，1，： | 1 |
| 7 | The Muhifaceted Functions of Neutrophils 显示文摘 | Mayadas T N Cullere X Lowell C A | 2014 | Annual Rev Pathol : Mechanisms Dis2014，9，： | 1 |
| 8 | Neutrophil beta2 integrins:moderators of life or death decisions显示文摘 | Mayadas TN Cullere X | 2005 | Trends Immunol2005，26，7： | 1 |
| 9 | Electrical-resistivity model for polycrystalline films: the case of arbitrary reflection at external surfaces显示文摘 | MAYADAS A E SHATZKES M | 1970 | Phys Rev BI1970，13，2： | 1 |
| 10 | Cytokine-activated endothelial cells delay neutrophil apoptosis in vitro and in vivo: a role for granulocyte/macrophage colony-stimulating factor 显示文摘 | Coxon A Tang T Mayadas TN | 1999 | J Exp Med1999，190，7： | 1 |
| 11 | Use of guar gum and gum arabic as bread improvers for the production of bakery products from sorghum flour显示文摘 | Abd Elmoneim O Elkhalifa Ashwagm Mohammed Mayada A Mustafa | 2007 | Food Sci Technol Res2007，13，4： | 1 |
| 12 | Vicinal cysteines in the pmsequence play a role in yon Willebrand factor multimer assembly 显示文摘 | Mayadas TN Wagner DD | 1992 | Proc Natl Acad Sci USA1992，89，： | 1 |
| 13 | Electrical-resistivity model for polycrystalline films: The case of arbitrary reflection at external surfaces显示文摘 | Mayadas A F Shatzkes M | 1970 | Phys Rev B11970，1，4： | 1 |
| 14 | Functions of TNF and its receptors in renal disease : distinct roles in inflammatory tissue injury and im- mune regulation 显示文摘 | Vielhauer V Mayadas TN | 2007 | Semin Nephrol2007，27，3： | 1 |
| 15 | CD11b/CD18 acts in concert with CDI4 and Toll-like receptor (TL) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression显示文摘 | Perera P Y Mayadas T N Takeuchi O | 2001 | J Immunol2001，166，： | 1 |
| 16 | Leukocyte rolling and ex-travasation are severely compromised in P-selection-deficient mice 显示文摘 | Johnson RC Raybum H | 1993 | Cell1993，74，54： | 1 |
| 17 | Renal cell-expressed TNF receptor 2,not receptor 1,is essential for the development of glomerulonephritis显示文摘 | Vielhauer V Stavrakis G Mayadas TN | 2005 | J Clin Invest2005，115，： | 1 |
| 18 | Credit rationing in small-scale enterprises: Special microenterprise programmes in ecuador显示文摘 | Mayada M. Baydas Richard L. Meyer Nelson Aguilera-Alfred | 1994 | Journal of Development Studies1994，，2： | 1 |
| 19 | Electrical-resistivity model for polycrystalline films:the caseof arbitrary reflection at external surfaces显示文摘 | Mayadas A F Shatzkes M | 1970 | Phys Rev B1970，1，： | 1 |
| 20 | Use of guar gum and gum arabic as bread improvers for the production of bakery products from sorghum flour显示文摘 | Abd Elmoneim O Elkhalifa Ashwagm Mohammed Mayada A Mustafa | 2007 | Food Sci Technol Res2007，13，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员