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| 1 | Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease: Responders versus nonresponders显示文摘瞄准:探索直肠的氮的氧化物(没有) 作为处理的简历标记,在 ulcerative (UC ) 和 Crohn 的反应是疾病(CD ) ,并且检验在之间的关系直肠没有,没有 synthases (NOS ) 的粘膜表示,和支持 inflammatory cytokines。方法:有 UC 的 22 个病人并且 24 在类固醇治疗期间与 CD 被监视。直肠没有层次被测量,临床的活动在天被估计 1, 3, 7 和 28。NOS 和支持 inflammatory cytokines 的粘膜存在被免疫组织化学和 RT-PCR 分析。结果:显著地显示的活跃 UC 和 CD 增加了直肠没有层次(10950 +/- 1280 每十亿分开的 7610 和 5040 +/-(ppb ) ,分别地) 作为与控制相比(154 +/- 71 ppb, P <
0.001 ) 。直肠不在 UC 和 CD 与疾病活动微弱地相关(r = 0.34 为 UC 和 r = 0.48 为 CD, P <
0.01 ) 。在 12 个病人,一堂类固醇倔强的功课导致了结肠切除术。仅仅稍微有的这些病人没增加层次(UC:620 +/- 270 ppb;CD:1260 +/- 550 ppb ) 与那些相比与治疗学的回答(UC:18860 +/- 530 ppb, P <
0.001;CD:10060 +/- 3200 ppb, P <
0.05 ) 。结论:直肠没有水平是在是的 IBD 的治疗反应的一个有用简历标记低没有层次预言差的临床的回答到类固醇治疗。 | Tryggve Ljung Sofie Lundberg Mark Varsanyi Catharina Johansson Peter T Schmidt Max Herulf Jon O Lundberg Per M Hellstr(o|¨)m | 2006 | World Journal of Gastroenterology2006，12，21： | 10 |
| 2 | Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair显示文摘AIM To determine endothelin-1(ET-1)concentration before and after surgical coarctectomy and evaluate its association with left ventricular geometric change.METHODSA prospective,cohort study of 24 patients aged 2 d to 10years with coarctation of the aorta undergoing surgical repair.A sub-cohort of patients with age<1 mo was classified as'neonates'.Echocardiograms were performed just prior to surgery and in the immediate post-op period to assess left ventricle mass index and relative wall thickness(RWT).Plasma ET-1 levels were assessed at both time points.Association between ET-1 levels and ventricular remodeling was assessed.RESULTSPatients<1 year demonstrated higher pre-op ET-1 than post-op(2.8 pg/m L vs 1.9 pg/m L,P=0.02).Conversely,patients>1 year had no change in ET-1 concentration before and after surgery(1.1 vs 1.4,NS).Pre-op,patients<1 year demonstrated significantly higher ET-1 than older children(2.8 vs 1.1,P=0.001).Post-op there was no difference between the age groups(1.9 vs 1.4,NS).Neither RWT nor left ventricle mass index(LVMI)varied from pre-op to post-op.The subset of neonates showed a strong positive correlation between pre-op ET-1 and RWT(r=0.92,P=0.001).Patients with ET-1>2 pg/m L preop demonstrated higher LVMI(65.7 g/m^(2.7) vs 38.5 g/m^(2.7),P=0.004)and a trend towards higher RWT(45%vs39%,P=0.07)prior to repair than those with lower ET-1concentration.CONCLUSIONET-1 concentration is significantly variable in the perioperative period surrounding coarctectomy.Older children and infants have different responses to surgical repair suggesting different mechanisms of activation. | Benjamin Steven Frank Tracy T Urban Suhong Tong Courtney Cassidy Max B Mitchell Christopher S Nichols Jesse A Davidson | 2017 | World Journal of Cardiology2017，9，12： | 2 |
| 3 | Softwood cuttings for propagation of red alder planting stock显示文摘 | Radwan M A T A Max D W Johnson | 1989 | New For1989，3，： | 1 |
| 4 | Stand structure in east side old-growth ponderosa pine forests of oregon and northern Califomia显示文摘 | YOUNG BLOOD A MAX T COE K | 2004 | Forest Ecology and Management2004，199，： | 1 |
| 5 | A clinical genetic method to identify mechanisms by which pain causes depression and anxiety 显示文摘 | Max MB Wu T Atlas SJ | 2006 | Mol Pain2006，19，2： | 1 |
| 6 | Transcripts of a chimeric cDNA of hepatitis C virus genotype lb are infectious in vivo显示文摘 | Masayuki Y Marisa S T Max S | 1998 | Virology1998，244，： | 1 |
| 7 | Accounting for the carbon associated with regional tourism consumption显示文摘 | Max M Karen T Calvin J | 2013 | Tourism Management2013，36，3： | 1 |
| 8 | Phylogenetic study on Shiraia bambusicola by rDNA sequence analyses显示文摘 | CHENG T F JIA X M MAX H | 2004 | J Basic Microbiol2004，44，5： | 1 |
| 9 | Stimulated stokes and anti-stokdes Raman scattering in liquid acetone with a bessel beam显示文摘 | Manz T Schwarz T Max M | 2004 | Optics Communication2004，235，： | 1 |
| 10 | Immunohistochemical analysis of integrin alpha v beta3 expression on tumor-associated vessels of human carcinomas显示文摘 | Max R Gerritsen R R Nooijen P T | 1997 | Int J Cancer1997，71，3： | 1 |
| 11 | A clinical genetic method to identify mechanisms by which pain causes depression and anxiety显示文摘 | Max MB Wu T Atlas SJ | 2006 | Mol Pain2006，2，： | 1 |
| 12 | Ignition and high gain with ultrapowerful lasers显示文摘 | Max T James H Micheal E G | 1994 | Phys Plasmas1994，1，5： | 1 |
| 13 | Optimization of culture conditions for production of cis-epoxysuccinic acid hydrolase using response surface methodology显示文摘 | LI X XU T C MAX H | | 0，，13： | 1 |
| 14 | Influence of culti-var,maturity storage,and storage conditions on phe-nolic composition and enzymatic browning of pear fruits显示文摘 | Marie J A Max T Serge Y A | | 0，，： | 1 |
| 15 | Epistatic interaction is an important genetic basis of grain yield and its components in maiz显示文摘 | MAX Q TANG J H TENG W T | 2007 | Mol Breed2007，20，： | 1 |
| 16 | Immunization with heat shock protein 70 from methylcholanthtene-induced sarcomas induces tumor protection correlating with in vitro T cell responses显示文摘 | Anne-Marie T Ciupitu Max Petersson | 2002 | Cancer Immunol Immunother2002，51，： | 1 |
| 17 | Comparison of retroperitoneoscopic nephrectomy versus open approaches to nonfunctioning tuberculous kidneys: a report of 44 cases显示文摘 | ZHANGX ZHENG T MAX | 2005 | J Urol2005，173，5： | 1 |
| 18 | Immunohistochemical analysis of intgerin alpha vbeta3 expression on tumor-associated vessels of human carcinomas显示文摘 | MAX R GERRITSEN R R NOOIJEN P T | 1997 | Int J Cancer1997，71，3： | 1 |
| 19 | Controlled solution deposition and systematic study of charge-transport anisot ropy in single crystal and single crystal textured TIPS pentacene thin films 显示文摘 | Chen J H Chee K T Max S | 2009 | Organic Electronics2009，10，4： | 1 |
| 20 | New pregnane glycosides from the roots of Cynanchum otophyllum 显示文摘 | MAX X JIANG F T YANG Q X | 2007 | Steroids2007，72，1112： | 1 |
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