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| 1 | A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility显示文摘Aromatase activity has commonly been associated with male infertility characterized by testicular dysfunction with low serum testosterone and/or testosterone to estradiol ratio.In this subset of patients,and particularly in those with hypogonadism,elevated levels of circulating estradiol may establish a negative feedback on the hypothalamic–pituitary–testicular axis by suppressing follicle-stimulating hormone(FSH)and luteinizing hormone(LH)production and impaired spermatogenesis.Hormonal manipulation via different agents such as selective estrogen modulators or aromatase inhibitors to increase endogenous testosterone production and improve spermatogenesis in the setting of infertility is an off-label option for treatment.We carried out a systematic review and meta-analysis of the literature of the past 30 years in order to evaluate the benefits of the use of aromatase inhibitors in the medical management of infertile/hypoandrogenic males.Overall,eight original articles were included and critically evaluated.Either steroidal(Testolactone)or nonsteroidal(Anastrozole and Letrozole)aromatase inhibitors were found to statistically improve all the evaluated hormonal and seminal outcomes with a safe tolerability profile.While the evidence is promising,future prospective randomized placebo-controlled multicenter trials are necessary to better define the efficacy of these medications. | Francesco Del Giudice Gian Maria Busetto Ettore De Berardinis Isabella Sperduti Matteo Ferro Martina Maggi Martin S Gross Alessandro Sciarra Michael L Eisenberg | 2020 | Asian Journal of Andrology2020,22,4: | 5 |
| 2 | Direct characterization of a nonlinear photonic circuit’s wave function with laser light显示文摘Integrated photonics is a leading platform for quantum technologies including nonclassical state generation1–4,demonstration of quantum computational complexity5 and secure quantum communications6.As photonic circuits grow in complexity,full quantum tomography becomes impractical,and therefore an efficient method for their characterization7,8 is essential.Here we propose and demonstrate a fast,reliable method for reconstructing the two-photon state produced by an arbitrary quadratically nonlinear optical circuit.By establishing a rigorous correspondence between the generated quantum state and classical sum-frequency generation measurements from laser light,we overcome the limitations of previous approaches for lossy multimode devices9,10.We applied this protocol to a multi-channel nonlinear waveguide network and measured a 99.28±0.31%fidelity between classical and quantum characterization.This technique enables fast and precise evaluation of nonlinear quantum photonic networks,a crucial step towards complex,largescale,device production. | Francesco Lenzini Alexander N Poddubny James Titchener Paul Fisher Andreas Boes Sachin Kasture Ben Haylock Matteo Villa Arnan Mitchell Alexander S Solntsev Andrey A Sukhorukov Mirko Lobino | 2018 | Light(Science & Applications)2018,7,1: | 2 |
| 3 | Detection and quanti- fication of airborne conidia of Fusarium circinatum, the causal agent of pine pitch canker, from two California sites by using a real - time PCR approach combined with a simple spore trapping method 显示文摘 | Wolfgang S Kerry 0 D Matteo G | 2004 | App Envir Micro2004,70,63: | 1 |
| 4 | Umbilical cord mesenchymal stem cells: role of regulatory genes in their differentiation to osteoblasts 显示文摘 | Ciavarella S Dammacco F De Matteo M | 2009 | Stem Cells Dev2009,35,1: | 1 |
| 5 | Action fluency in Parkinson's disease:a follow-up study显示文摘 | MATTEO S CHIARA V | 2006 | Movement Disorders2006,21,4: | 1 |
| 6 | Intratesticular feedback mechanisms in the regulation of steroid profiles in the frog,Rana esculenta显示文摘 | Fasano S Minucci S Di Matteo L | 1989 | Gen Comp Endocrinol1989,75,3: | 1 |
| 7 | The orbital glands of the terrapin Pseudemys scripta in response to osmotic stress:a light and electron microscope study显示文摘 | Baccari G C Minucci S Di Matteo L | 1993 | J Anat1993,183,1: | 1 |
| 8 | Advanced precancerous lesions within the GI tract: The molecular background显示文摘 | Matteo Fassan Raffaele Baffa András Kiss | 2013 | Best Practice & Research Clinical Gastroenterology2013,,2: | 1 |
| 9 | Increased C-reactive protein concentrations in never-treated hypertension: the role of systolic and pulse pressures显示文摘 | GIUSEPPE S MATTEO P FABIO G | 2003 | J Hypertension2003,21,10: | 1 |
| 10 | A cost-of-illness study of spina bifida in Italy显示文摘 | Colombo GL Di Matteo S Vinci M | 2013 | Clinicoecon Outcomes Res2013,5,3: | 1 |
| 11 | Prognostic value of the metabolic syndrome in essential hypertension显示文摘 | Giuseppe S Matteo P Gaetano V | 2004 | J Am Coll Cardiol2004,43,10: | 1 |
| 12 | Detachment folding in the central and eastern Zagros fold-belt (Iran):salt mobility,multiple detach-ments and late basement control显示文摘 | Shahram S Matteo M Dominique F L | | 0,,9: | 1 |
| 13 | Learning from data: a tutorial with emphasis on modern pattern recognition methods显示文摘 | Matteo P Giorgio S | 2002 | IEEE Sensors Journal2002,2,3: | 1 |
| 14 | Evolution of compressive strains in retained austenite during sub-zero Celsius martensite formation and tempering 显示文摘 | Matteo V Karen P Marcel A J S | 2014 | Acta Materialia2014,65,: | 1 |
| 15 | Identification of the etiology of primary aldosteronism with adrenal vein sampling in patients with equivocal computed tomography and magnetic resonance fin-dings: results in 104 consecutive cases显示文摘 | Gian PR Alferedo S Matteo CC | 2001 | J Clin Endocrinol Metab2001,86,3: | 1 |
| 16 | Acan- thamoeba keratitis with perforation after corneal cross-linking and bandage contact lens use 显示文摘 | Rama P Di Matteo F Matuska S Paganoni G Spinelli A | 2009 | J Cataract Refract Surg2009,35,4: | 1 |
| 17 | Micromedullary thyroid carcinoma: school experience 显示文摘 | Palermo S Di Matteo FM Savino G | 2010 | G Chir2010,31,67: | 1 |
| 18 | Mesenchymal stem cells and bone regeneration显示文摘 | Ciavarel a S De Matteo M Cafforio P | | 0,,02: | 1 |
| 19 | Prognostic value of the metabolic syn- drome in essential hypertension显示文摘 | Giuseppe S Matteo P Gaetano V | 2004 | J Am Coil Cardio12004,43,: | 1 |
| 20 | Role of tumor necrosis factor a release and leukocyte margination in indomethacin-induced gastric injury in rats显示文摘 | Santucci L Fiorucci S Di Matteo FM | 1995 | Gastroenterology1995,108,2: | 1 |