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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Focal liver lesions:Practical magnetic resonance imaging approach显示文摘With the widespread of cross-sectional imaging, a growth of incidentally detected focal liver lesions(FLL) has been observed. A reliable detection and characterization of FLL is critical for optimal patient management. Maximizing accuracy of imaging in the context of FLL is paramount in avoiding unnecessary biopsies, which may result in post-procedural complications. A tremendous development of new imaging techniques has taken place during these last years. Nowadays, Magnetic resonance imaging(MRI) plays a key role in management of liver lesions, using a radiation-free technique and a safe contrast agent profile. MRI plays a key role in the non-invasive correct characterization of FLL. MRI is capable of providing comprehensive and highly accurate diagnostic information, with the additional advantage of lack of harmful ionizing radiation. These properties make MRI the mainstay for the noninvasive evaluation of focal liver lesions. In this paper we review the state-of-the-art MRI liver protocol, briefly discussing different sequence types, the unique characteristics of imaging non-cooperative patients and discuss the role of hepatocyte-specific contrast agents. A review of the imaging features of the most common benign and malignant FLL is presented, supplemented by a schematic representation of a simplistic practical approach on MRI. | António P Matos Fernanda Velloni Miguel Ramalho Mamdoh AlObaidy Aruna Rajapaksha Richard C Semelka | 2015 | World Journal of Hepatology2015，7，16： | 6 |
| 3 | Magnetic resonance imaging ancillary features used in Liver Imaging Reporting and Data System:An illustrative review显示文摘Hepatocellular carcinoma (HCC) usually develops in the setting of chronic liver disease. In the adequate clinical context, both multiphasic contrast-enhanced CT and magnetic resonance imaging are non-invasive modalities that allow accurate diagnosis and staging of HCC, although the latter demonstrates greater sensitivity and specificity. Imaging criteria for HCC diagnosis rely on hemodynamic features such as hyperenhancement in the arterial phase and washout in the portal or equilibrium phase. However, imaging performance drops considerably for small (< 20 mm) nodules because their tendency to exhibit atypical enhancement patterns. In order to improve accuracy in the diagnosis and staging of HCC, particularly in cases of atypical nodules, ancillary features, i.e., imaging characteristics that modify the likelihood of HCC, have been described and incorporated into clinical reports, especially in Liver Imaging Reporting and Data System. In this paper, ancillary imaging features will be reviewed and illustrated. | David Campos-Correia Joao Cruz António P Matos Filipa Figueiredo Miguel Ramalho | 2018 | World Journal of Radiology2018，10，2： | 3 |
| 4 | Improvements for mass-exchange networks design 显示文摘 | Castro P Matos H Fernandes M C | 1999 | Chemical Engineering Science1999，54，： | 1 |
| 5 | Validation of an immunoperoxidase monolayer assay for total anti-Vac- cinia virus antibody titration 显示文摘 | Gerber P F Matos A C Guedes M I | 2012 | J Vet Diagn Invest2012，24，2： | 1 |
| 6 | Increased Racl b expression sustains colorectal tumor cell survival 显示文摘 | Matos P Jordan P | 2008 | Mol Cancer Res2008，6，7： | 1 |
| 7 | Competitive adsorption of zinc,cadmium,copper and lead in three highly weathered Brazilian soils显示文摘 | Fontes M P F Matos A F Costa L M | 2000 | Commun Soil Sci Plant Anal2000，31，： | 1 |
| 8 | Primary infection of goats with Eimeria ninakohlyakimovae does not provide protective immunity against high challenge infections显示文摘 | A. Ruiz M.C. Mu?oz J.M. Molina C. Hermosilla F. Rodríguez M. Andrada S. Martín A.Guedes D. Pérez L. Matos A.M. López A. Taubert | 2013 | Small Ruminant Research2013，，1： | 1 |
| 9 | Loss allocation in distribution net- works with embedded generation显示文摘 | Costa P M Matos M A | 2004 | IEEE Trans on Power Systems2004，19，1： | 1 |
| 10 | Copropagating and counterpropagating pumps in second-order-pumped discrete fiber Raman amplifiers显示文摘 | Chestnut D A de Matos C J S Reeves-Hall P C | 2002 | Optics Letters2002，27，19： | 1 |
| 11 | A method for calculating stress intensities in bimaterial fracture 显示文摘 | Matos P P L McMeeking R M Charalambides P G | 1989 | International Journal Fracture1989，40，： | 1 |
| 12 | Quantum communications at ESA: towards a space experiment on the ISS 显示文摘 | Armengol J M P Furch B Matos C J | | Acta Astronautica0，63，14： | 1 |
| 13 | Favoritism in Mutual Fund Families? Evidence on Strategic Cross-fund Subsidization 显示文摘 | GASPAR J M MASSA M MATOS P | 2006 | Journal of Finance2006，2，1： | 1 |
| 14 | An improved RTN continuous-time formulation for the short-term scheduling of multipurpose batch plants 显示文摘 | CASTRO P BARBOSA-Povoa A P F D MATOS H | 2001 | Industrial and Engineering Chemistry Research2001，40，9： | 1 |
| 15 | The Colors of Investors' Money:The Role of Institutional Investors Around the World显示文摘 | Ferreira M A Matos P | 2008 | Journal of Financial Economics2008，88，： | 1 |
| 16 | Multiperiod synthesis and operational planning of utility systems with environmental concerns 显示文摘 | FRANCISCO O A P MATOS H A | 2004 | Computers and Chemical Engineering2004，28，5： | 1 |
| 17 | Small GTPase Rac1:structure,localisation and expression of the human gene显示文摘 | Matos P Skaug J Marques B | 2000 | Biochem Biophys Res Commun2000，277，3： | 1 |
| 18 | The electrochemical oxidation of xylitol on Pt(Ⅲ) in acid medium显示文摘 | MATOS J P F PROENCA L LOPES M I S | 2004 | J Electroanal Chem2004，571，： | 1 |
| 19 | Small GTPase Racl : structure,localization,and expression of the human gene显示文摘 | Matos P Skaug J Marques B | 2000 | Biochem Biophys Res Commun2000，277，3： | 1 |
| 20 | Thermal decompo- sition of hydrated |anthanide picrates by TG/DTG and DSC an- alyses显示文摘 | Miranda Jr P Matos J R Mercuri L P | 2002 | J Therm Anal Calorim2002，67，2： | 1 |
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