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| 1 | Clarifying sub-genomic positions of QTLs for flowering habit and fruit quality in U.S. strawberry (Fragaria×ananassa) breeding populations using pedigree-based QTL analysis显示文摘The cultivated strawberry(Fragaria×ananassa)is consumed worldwide for its flavor and nutritional benefits.Genetic analysis of commercially important traits in strawberry are important for the development of breeding methods and tools for this species.Although several quantitative trait loci(QTL)have been previously detected for fruit quality and flowering traits using low-density genetic maps,clarity on the sub-genomic locations of these QTLs was missing.Recent discoveries in allo-octoploid strawberry genomics led to the development of the IStraw90 single-nucleotide polymorphism(SNP)array,enabling high-density genetic maps and finer resolution QTL analysis.In this study,breeder-specified traits were evaluated in the Eastern(Michigan)and Western(Oregon)United States for a common set of breeding populations during 2 years.Several QTLs were validated for soluble solids content(SSC),fruit weight(FWT),pH and titratable acidity(TA)using a pedigree-based QTL analysis approach.For fruit quality,a QTL for SSC on linkage group(LG)6A,a QTL for FWT on LG 2BII,a QTL for pH on LG 4CII and two QTLs for TA on LGs 2A and 5B were detected.In addition,a large-effect QTL for flowering was detected at the distal end of LG 4A,coinciding with the FaPFRU locus.Marker haplotype analysis in the FaPFRU region indicated that the homozygous recessive genotype was highly predictive of seasonal flowering.SNP probes in the FaPFRU region may help facilitate marker-assisted selection for this trait. | Sujeet Verma Jason D Zurn Natalia Salinas Megan M Mathey Beatrice Denoyes James F Hancock Chad E Finn Nahla V Bassil Vance M Whitaker | 2017 | Horticulture Research2017，4，1： | 10 |
| 2 | Type 1 diabetes and polyglandular autoimmune syndrome: A review显示文摘Type 1 diabetes(T1D) is an autoimmune disorder caused by inflammatory destruction of the pancreatic tissue. The etiopathogenesis and characteristics of the pathologic process of pancreatic destruction are well described. In addition, the putative susceptibility genes for T1 D as a monoglandular disease and the relation to polyglandular autoimmune syndrome(PAS) have also been wellexplored. The incidence of T1 D has steadily increased in most parts of the world, especially in industrialized nations. T1 D is frequently associated with autoimmune endocrine and non-endocrine diseases and patients with T1 D are at a higher risk for developing several glandular autoimmune diseases. Familial clustering is observed, which suggests that there is a genetic predisposition. Various hypotheses pertaining to viral- and bacterialinduced pancreatic autoimmunity have been proposed, however a definitive delineation of the autoimmune pathomechanism is still lacking. In patients with PAS, pancreatic and endocrine autoantigens either colocalize on one antigen-presenting cell or are expressed on two/various target cells sharing a common amino acid, which facilitates binding to and activation of T cells. The most prevalent PAS phenotype is the adult type 3 variant or PAS type Ⅲ, which encompasses T1 D and autoimmune thyroid disease. This review discusses the findings of recent studies showing noticeable differences in the genetic background and clinical phenotype of T1 D either as an isolated autoimmune endocrinopathy or within the scope of polyglandular autoimmune syndrome. | Martin P Hansen Nina Matheis George J Kahaly | 2015 | World Journal of Diabetes2015，6，1： | 7 |
| 3 | Left-sided colon and colorectal anastomoses: doppler ultrasound as an aid to assess bowel vascularization显示文摘 | P. Ambrosetti J. Robert P. Mathey A. Rohner | 1994 | International Journal of Colorectal Disease1994，，4： | 2 |
| 4 | Irritable bowel syndrome and chronic pelvic pain: A singular or two different clinical syndrome?显示文摘Irritable bowel syndrome (IBS) and chronic pelvic pain (CPP) are both somatoform disorders with a high prevalence within the population in general. The objective was to compare both entities, to fi nd the differences and the similarities related to epidemiology and psychosocial aspects like stressful life events, physical and sexual abuse, illness behaviour and comorbidity. The technical literature was reviewed systematically from 1971 to 2006 and compared. According to literature, IBS and CPP seem to be one rather than two different entities with the same localisation of pain. Both syndromes also are similar concerning prevalence, the coexistence of mental and somatoform disorders, the common history of sexual and physical abuse in the past and their health care utilization. It could be shown that there were many similarities between IBS and CPP. Nevertheless both are traded as different clinical pictures as far. Therefore it seems to be reasonable and necessary to generate a common diagnosis algorithm and to bring gynaecologists and gastroenterologists into dialogue. | Anna Matheis Ute Martens Johannes Kruse Paul Enck | 2007 | World Journal of Gastroenterology2007，13，25： | 2 |
| 5 | Forest planning using co-ev-olutionary cellular automata显示文摘 | Mathey E Krcmar J Innes D Tait | 2007 | Forest Ecology and Management2007，239，13： | 1 |
| 6 | Expression and distribution of transcription factor NF-kB and inhibitor IkB in the in flamed peripheral nervous system显示文摘 | Bettina Andorfer Bernd C Kieseier Emily Mathey | 2001 | Journal of Neuroimmunology2001，116，： | 1 |
| 7 | 显示文摘 | Michael H Penner R E | 1983 | J Agric Food Chem1983，31，2： | 1 |
| 8 | Avoiding reperfusion injury after limb revascularization: experimental observation and recommendations for clinical application 显示文摘 | Beyersdorf F Matheis G Kruger S | 1989 | J Vase Surg1989，9，6： | 1 |
| 9 | Assessment of the vortex method for large eddy simulation inlet conditions显示文摘 | Mathey F Cokljat D Bertoglio J P | 2006 | Progressin Computational Fluid Dynamics2006，6，13： | 1 |
| 10 | Safety and immunogenicity of a hepatitis B vaccine formulated with a novel adjuvant system显示文摘 | S. Thoelen P. Van Damme C. Mathei G. Leroux-Roels I. Desombere A. Safary P. Vandepapeliere M. Slaoui A. Meheus | 1998 | Vaccine1998，，7： | 1 |
| 11 | Synthetic protein treated versus heparin coated eardiopulmonary bypass surfaces:similar clinical results and minor biochemieal differences显示文摘 | Matheis G Martens S | 1999 | Eur J Cardiothorae Surg1999，16，2： | 1 |
| 12 | Circulating endothelin in patients undergoing coronary artery bypass grafting显示文摘 | Matheis G Haak T Baretti R | 1995 | Eur J Cardiothorac Surg1995，9，5： | 1 |
| 13 | Enzymatic cross-linking of proteins applicable to foods 显示文摘 | MATHEIS G WHITAKER J R | 1987 | Food Biochem1987，11，： | 1 |
| 14 | Muscle strength and physical performance as predictors of mortality, hospitaliza- tion, and disability in the oldest old显示文摘 | Legrand D Vaes B Mathei C | 2014 | J Am Geriatr Soc2014，62，6： | 1 |
| 15 | Molecular epidemiology of hepatitis C among drug users in Flanders, Belgium :association of genotype with clinical parameters and with sex - and drug - related risk behaviours 显示文摘 | MATHEI C WOLLANTS E VERBEECK J | 2005 | Eur J Clin Micrnbiol2005，24，8： | 1 |
| 16 | 显示文摘 | | 1991 | Food Chem1991，，39： | 1 |
| 17 | Feasibility and efficacy of balloon-based neuroprotection during carotid artery stenting in a single-center setting显示文摘 | Schluter M Tubler T Mathey DG | | 0，，： | 1 |
| 18 | Chemical phosphorylation of food protein: an overview and a prospectus 显示文摘 | Matheis G John R W | 1984 | Agriculture Food Chemistry1984，32，： | 1 |
| 19 | Avian encephalomyelitis in pheasant显示文摘 | Mathey W J | 1995 | Cornell Veterinarian1995，45，： | 1 |
| 20 | The prevalence of sarcopenia in very old individuals according to the European consensus definition: insights from the BELFRAIL study显示文摘 | Legrand D Vaes B Mathei C | 2013 | Age Ageing2013，42，72： | 1 |
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