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| 1 | Endoscopic submucosal dissection vs endoscopic mucosal resection for early gastric cancer: A meta-analysis显示文摘AIM: To compare endoscopic submucosal dissection(ESD) and endoscopic mucosal resection(EMR) for early gastric cancer(EGC).METHODS: Computerized bibliographic search was performed on PubMed/Medline, Embase, Google Schol-ar and Cochrane library databases. Quality of each included study was assessed according to current Co-chrane guidelines. Primary endpoints were en bloc re-section rate and histologically complete resection rate. Secondary endpoints were length of procedure, post-treatment bleeding, post-procedural perforation and re-currence rate. Comparisons between the two treatment groups across all the included studies were performed by using Mantel-Haenszel test for fixed-effects mod-els(in case of low heterogeneity) or DerSimonian and Laird test for random-effects models(in case of high heterogeneity).RESULTS: Ten retrospective studies(8 full text and 2 abstracts) were included in the meta-analysis. Overall data on 4328 lesions, 1916 in the ESD and 2412 in the EMR group were pooled and analyzed. The mean operation time was longer for ESD than for EMR(stan-dardized mean difference 1.73, 95%CI: 0.52-2.95, P =0.005) and the 'en bloc ' and histological complete re-section rates were significantly higher in the ESD group [OR = 9.69(95%CI: 7.74-12.13), P < 0.001 and OR = 5.66,(95%CI: 2.92-10.96), P < 0.001, respectively]. As a consequence of its greater radicality, ESD provided lower recurrence rate [OR = 0.09,(95%CI: 0.05-0.17), P < 0.001]. Among complications, perforation rate was significantly higher after ESD [OR = 4.67,(95%CI, 2.77-7.87), P < 0.001] whereas the bleeding incidences did not differ between the two techniques [OR = 1.49(0.6-3.71), P = 0.39].CONCLUSION: In the endoscopic therapy of EGC, ESD showed a superior efficacy but higher complication rate with respect to EMR. | Antonio Facciorusso Matteo Antonino Marianna Di Maso Nicola Muscatiello | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，11： | 50 |
| 2 | Non-polypoid colorectal neoplasms:Classification,therapy and follow-up显示文摘In the last years,an increasing interest has been raised on non-polypoid colorectal tumors(NPT) and in particular on large flat neoplastic lesions beyond 10 mm tending to grow laterally,called laterally spreading tumors(LST).LSTs and large sessile polyps have a greater frequency of high-grade dysplasia and local invasiveness as compared to pedunculated lesions of the same size and usually represent a technical challenge for the endoscopist in terms of either diagnosis and resection.According to the Paris classification,NPTs are distinguished in slightly elevated(0-Ⅱa,less than 2.5 mm),flat(0-Ⅱb) or slightly depressed(0-Ⅱc).NPTs are usually flat or slightly elevated and tend to spread laterally while in case of depressed lesions,cell proliferation growth progresses in depth in the colonic wall,thus leading to an increased risk of submucosal invasion(SMI) even for smaller neoplasms.NPTs may be frequently missed by inexperienced endoscopists,thus a careful training and precise assessment of all suspected mucosal areas should be performed.Chromoendoscopy or,if possible,narrow-band imaging technique should be considered for the estimation of SMI risk of NPTs,and the characterization of pit pattern and vascular pattern may be useful to predict the risk of SMI and,therefore,to guide the therapeutic decision.Lesions suitable to endoscopic resection are those confined to the mucosa(or superficial layer of submucosa in selected cases) whereas deeper invasion makes endoscopic therapy infeasible.Endoscopic mucosal resection(EMR,piecemeal for LSTs > 20 mm,en bloc for smaller neoplasms) remains the first-line therapy for NPTs,whereas endoscopic submucosal dissection in high-volume centers or surgery should be considered for large LSTs for which en bloc resection is mandatory and cannot be achieved by means of EMR.After piecemeal EMR,follow-up colonoscopy should be performed at 3 mo to assess resection completeness.In case of en bloc resection,surveillance colonoscopy should be scheduled at 3 years for adenomatous lesions ≥ 1 cm,or in presence of villous features or high-grade dysplasia patients(regardless of the size),while less intensive surveillance(colonoscopy at 5-10 years) is needed in case of single(or two) NPT < 1 cm presenting tubular features or low-grade dysplasia at histology. | Antonio Facciorusso Matteo Antonino Marianna Di Maso Michele Barone Nicola Muscatiello | 2015 | World Journal of Gastroenterology2015，21，17： | 20 |
| 3 | Development and validation of a risk score for advanced colorectal adenoma recurrence after endoscopic resection显示文摘AIM: To develop and validate a risk score for advanced colorectal adenoma(ACA) recurrence after endoscopic polypectomy.METHODS: Out of 3360 patients who underwent colon polypectomy at University of Foggia between 2004 and 2008, data of 843 patients with 1155 ACAs was retrospectively reviewed. Surveillance intervals were scheduled by guidelines at 3 years and primary endpoint was considered 3-year ACA recurrence. Baseline clinical parameters and the main features of ACAs were entered into a Cox regression analysis and variables with P < 0.05 in the univariate analysis were then tested as candidate variables into a stepwise Cox regression model(conditional backward selection). The regression coefficients of the Cox regression model were multiplied by 2 and rounded in order to obtain easy to use point numbers facilitating the calculation of the score. To avoid overoptimistic results due to model fitting and evaluation in the same dataset, we performed an internal 10-fold cross-validation by means of bootstrap sampling. RESULTS: Median lesion size was 16 mm(12-23) while median number of adenomas was 2.5(1-3), whereof the number of ACAs was 1.5(1-2). At 3 years after polypectomy, recurrence was observed in 229 ACAs(19.8%), of which 157(13.5%) were metachronous neoplasms and 72(6.2%) local recurrences. Multivariate analysis, after exclusion of the variable 'type of resection' due to its collinearity with other predictive factors, confirmed lesion size, number of ACAs and grade of dysplasia as significantly associated to the primary outcome. The score was then built by multiplying the regression coefficients times 2 and the cut-off point 5 was selected by means of a Receiver Operating Characteristic curve analysis. In particular, 248 patients with 365 ACAs fell in the higher-risk group(score ≥ 5) where 3-year recurrence was detected in 174 ACAs(47.6%) whereas the remaining 595 patients with 690 ACAs were included in the low-risk group(score < 5) where 3-year recurrence rate was 7.9%(55/690 ACAs). Area under the curve of the model was 0.81(0.72-0.86) with an overall classification error rate of 0.09. The model was finally validated by means of 10-fold cross validation.CONCLUSION: Our study provides support for the use of a novel risk score as a clinical predictor of ACA recurrence after colon polypectomy. | Antonio Facciorusso Marianna Di Maso Gaetano Serviddio Gianluigi Vendemiale Nicola Muscatiello | 2016 | World Journal of Gastroenterology2016，22，26： | 8 |
| 4 | 会阴侧切术对阴道分娩后骨盆底组织功能的影响 | Sartore A. De Seta F. Maso G. 李跃萍 | 2005 | 世界核心医学期刊文摘(妇产科学分册)2005，0，8： | 5 |
| 5 | Hepatitis C virus and non-Hodgkin's lymphomas:Metaanalysisof epidemiology data and therapy options显示文摘Hepatitis C virus(HCV) is a global health problem affecting a large fraction of the world's population: This virus is able to determine both hepatic and extrahepatic diseases. Mixed cryoglobulinemia, a B-cell 'benign' lymphoproliferative disorders, represents the most closely related as well as the most investigated HCVrelated extrahepatic disorder. Since this virus is able to determine extrahepatic [non-Hodgkin's lymphoma(NHL)] as well as hepatic malignancies(hepatocellular carcinoma), HCV has been included among human cancer viruses. The most common histological types of HCV-associated NHL are the marginal zone, the lymphoplasmacytic and diffuse large cell lymphomas. The role of the HCV in the pathogenesis of the B-cell lymphoproliferative disorders is confirmed also by the responsiveness of the NHL to antiviral therapy. The purpose of this review is to provide an overview of the recent literature and a meta analysis of the epidemiology data, to explain the role of HCV in the development of NHL's lymphoma. Furthermore, the possibility to treat these HCV-related NHL with the antiviral therapy or with other therapeutic options, like chemotherapy, is also discussed. | Gabriele Pozzato Cesare Mazzaro Luigino Dal Maso Endri Mauro Francesca Zorat Giulia Moratelli PietroBulian Diego Serraino Valter Gattei | 2016 | World Journal of Hepatology2016，8，2： | 3 |
| 6 | Polidocanol injection decreases the bleeding rate after colon polypectomy: a propensity score analysis显示文摘 | Antonio Facciorusso Marianna Di Maso Matteo Antonino Valentina Del Prete Carmine Panella Michele Barone Nicola Muscatiello | 2015 | Gastrointestinal Endoscopy2015，，2： | 2 |
| 7 | Manifestations of Chronic Hepatitis C Virus Infection Beyond the Liver显示文摘 | Ira M. Jacobson Patrice Cacoub Luigino Dal Maso Stephen A. Harrison Zobair M. Younossi | 2010 | Clinical Gastroenterology and Hepatology2010，，12： | 2 |
| 8 | Food Restriction,Performance, Psychological State and Lipid Values in Judo Athletes显示文摘 | FILAIRE E MASO F DEGOUTTE F | 2001 | Int J Sports Med2001，22，6： | 1 |
| 9 | History of weight and obesity through life and risk of benign prostatic hyperplasia 显示文摘 | Zucchetto A Tavani A Dal Maso L | 2005 | hat J Obes2005，29，7： | 1 |
| 10 | GEOEssential–mainstreaming workflows from data sources to environment policy indicators with essential variables显示文摘When defining indicators on the environment,the use of existing initiatives should be a priority rather than redefining indicators each time.From an Information,Communication and Technology perspective,data interoperability and standardization are critical to improve data access and exchange as promoted by the Group on Earth Observations.GEOEssential is following an end-user driven approach by defining Essential Variables(EVs),as an intermediate value between environmental policy indicators and their appropriate data sources.From international to local scales,environmental policies and indicators are increasingly percolating down from the global to the local agendas.The scientific business processes for the generation of EVs and related indicators can be formalized in workflows specifying the necessary logical steps.To this aim,GEOEssential is developing a Virtual Laboratory the main objective of which is to instantiate conceptual workflows,which are stored in a dedicated knowledge base,generating executable workflows.To interpret and present the relevant outputs/results carried out by the different thematic workflows considered in GEOEssential(i.e.biodiversity,ecosystems,extractives,night light,and food-water-energy nexus),a Dashboard is built as a visual front-end.This is a valuable instrument to track progresses towards environmental policies. | Anthony Lehmann Stefano Nativi Paolo Mazzetti Joan Maso Ivette Serral Daniel Spengler Aidin Niamir Ian McCallum Pierre Lacroix Petros Patias Denisa Rodila Nicolas Ray Grégory Giuliani | 2020 | International Journal of Digital Earth2020，13，2： | 1 |
| 11 | Formation and growth of fresh atmospheric aerosols:eight years of aerosol size distribution data from SMEAR Ⅱ,Hyyti?l?,Finland 显示文摘 | Maso M D Kulmala M Riipinen I | 2005 | Boreal Environment Research2005，10，5： | 1 |
| 12 | Chaudry IH:mechanism of immune suppression in males following trauma-hemorrhage:critical role of testosterone显示文摘 | Wichmann M Zellweger R De Maso C M | 1996 | Arch Surg1996，131，： | 1 |
| 13 | Voting Behavior, Coalitions and Government Strength through a Complex Network Analysis 显示文摘 | Dal Maso C Pompa G Puliga M Riotta G Chessa A | 2014 | Plos ONE2014，9，12： | 1 |
| 14 | Risk factors for thyroid cancer:an epidemiological review focused on nutritional factors显示文摘 | Dal Maso L Bosetti C La Vecchia C | 2009 | Cancer Causes Control2009，20，1： | 1 |
| 15 | Sertraline ( )reatment of transition-associated anxiety and agitation in children with autistic disorder显示文摘 | EIGARD RJ ZIMNITZKY B DE MASO DR | 1997 | J Child Adolesc Psychopharmacol1997，7，： | 1 |
| 16 | Prevalence and determinants of Human papillomavirus genital infection in men显示文摘 | Franceschi S Castellsague X Dal Maso L | 2002 | Br J Cancer2002，86，： | 1 |
| 17 | Superimposed technique for OFDM/OQAM based digital terrestrial television broadcasting显示文摘 | GOLJAHANI A VANGELISTA L MASO M | 2008 | Electrical and Electronics Engineers in Israel2008，35，12： | 1 |
| 18 | Effect of obesity and other lifestyle factors on mortality in women with breast cancer显示文摘 | Dal Maso L Zucchetto A Talamini R | 2008 | Int J Cancer2008，123，9： | 1 |
| 19 | Effect of damage in reinforced concrete on carbonation or chloride penetration显示文摘 | FRANCOIS R MASO J C | 1988 | Cement and Concrete Research1988，18，6： | 1 |
| 20 | Sex homrones profile in women on dialysis program in treatment with erythropoietin显示文摘 | Dal Maso RC Cavagna Neto M Yu L | 2003 | Rev Assoc Med Bras2003，49，： | 1 |
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