|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Expression of DNA repair proteins hMSH2, hMSH6, hMLH1, O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA Glycosylase in melanoma cells with acquired drug resistance 显示文摘 | HERMANN L MARKS CH MONIKA A | 1999 | Int J Cancer1999，80，： | 1 |
| 2 | DiI{erential activation of NF-kB and AP-1 in increased {ibronectin synthesis in target organs of diabetic complications显示文摘 | Shall CH Khan ZA Mark C | 2003 | Am J Physiol Endocrinol Metab2003，284，6： | 1 |
| 3 | PI3 - K/Akt - mediated anoikis resistance of human osteosarcoma cells requires Src activation 显示文摘 | Mark CH | 2006 | Eur J Cancer2006，42，10： | 1 |
| 4 | Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands 显示文摘 | MARK CH YOUGEN XI KIMBERLY W | 2001 | Cytokine and Growth Factor Reviews2001，12，1： | 1 |
| 5 | Outcomes of contact investigations of infectious tuberculosis patients显示文摘 | Marks SM Taylor Z quails NL shrestha-kuwahara RJ wilce MA Neuyen CH | 2000 | Am J Reslair Crit Care Med2000，162，6： | 1 |
| 6 | Increased caesarean section rates and emerging patterns of health insurance in Shanghai,China显示文摘 | Cai WW Marks JS Chen CH | 1998 | Am J Pub Health1998，88，5： | 1 |
| 7 | Assessment of sex chromosome composition using fluorescent in situ hybridization as an adjunct to GTG-banding显示文摘 | Mark HF Meyers-Seifer CH Seifer DB | 1995 | Ann Clin Lab Sci1995，25，： | 1 |
| 8 | Quantitative molecular parameters to identify low and high risk early CIN lesions: role of markers of Proliferative activity and differentiation and Rb availability 显示文摘 | Mark S Lucy CH Julie EB | 2004 | Int J Gynocel Pathol2004，23，2： | 1 |
| 9 | Pnpt1 mediates NLRP3 inflammasome activation by MAVS and metabolic reprogramming in macrophages显示文摘Polyribonucleotide nucleotidyltransferase 1(Pnpt1)plays critical roles in mitochondrial homeostasis by controlling mitochondrial RNA(mt-RNA)processing,trafficking and degradation.Pnpt1 deficiency results in mitochondrial dysfunction that triggers a type I interferon response,suggesting a role in inflammation.However,the role of Pnpt1 in inflammasome activation remains largely unknown.In this study,we generated myeloid-specific Pnpt1-knockout mice and demonstrated that Pnpt1 depletion enhanced interleukin-1 beta(IL-1β)and interleukin-18(IL-18)secretion in a mouse sepsis model.Using cultured peritoneal and bone marrow-derived macrophages,we demonstrated that Pnpt1 regulated NLRP3 inflammasome-dependent IL-1βrelease in response to lipopolysaccharide(LPS),followed by nigericin,ATP or poly(I:C)treatment.Pnpt1 deficiency in macrophages increased glycolysis after LPS administration and mt-reactive oxygen species(mt-ROS)after NLRP3 inflammasome activation.Pnpt1 activation of the inflammasome was dependent on increased glycolysis and the expression of mitochondrial antiviral-signaling protein(MAVS)but not NF-κB signaling.Collectively,these data suggest that Pnpt1 is an important mediator of inflammation,as shown by activation of the NLRP3 inflammasome in murine sepsis and cultured macrophages. | Chia George Hsu Wenjia Li Mark Sowden Camila Lage Chávez Bradford C.Berk | 2023 | Cellular & Molecular Immunology2023，20，2： | 1 |
| 10 | Role of Heme Oxygenase- 1 in the Regulation of Blood Pressure and Cardiac Function 显示文摘 | Yen Hsn Ch Shaw Fang Y Mark A Perrella | 2003 | EXP BIOL MED2003，228，： | 1 |
| 11 | The hERG potassium channel and hERG screening for drug - induced torsades de pointes显示文摘 | Jules CH Mark JM Aziza EH | 2008 | Phar- macol Ther2008，119，2： | 1 |
| 12 | Influenza vaccination programs for elderly persons: cost-effectiveness in a health maintenance organiza- tion显示文摘 | John PM Marjorie DB Mark CH | 1994 | Ann Intern Med1994，121，： | 1 |
| 13 | Domestic control of house dust mite allergen in children's beds显示文摘 | Vanlaar CH Peat JK Marks GB | 2000 | J Allergy Clin Immunol2000，105，61： | 1 |
| 14 | Propofol, a review of its pharmacodynamic and pharmacokinetic properties and use a intravenous anaesthetic显示文摘 | MARK SL RENNIE CH | 1988 | Drug Evaluat ion1988，35，： | 1 |
| 15 | Experimental crytosporidium parvum infections in immunosuppressed adult mice显示文摘 | Kathleen R Rasmussen Mark CH | 1992 | Infection and Immunity1992，60，4： | 1 |
| 16 | Measurement of Cadaver Lumbar Spine Motion Segment Stiffness显示文摘 | Mark DB David CH Anneliese DH | 2002 | Spine2002，27，： | 1 |
| 17 | High-performance liquid chromatographic determination of imidazole dipeptides, histidine, 1-methylhis-tidine and 3-methylhistidine in equine and camel muscle and individual muscle fibres显示文摘 | Mark D Roger CH | 1997 | Journal ofChroma tography B1997，688，： | 1 |
| 18 | Increased cesarean section rates and emerging patterns of health insurance in Shanghai, China显示文摘 | Cai WW Marks JS Chen CH | 1995 | Am J Public Health1995，88，： | 1 |
| 19 | Determination of camosine and other biogenic imidazoles in equine plasma by isocratic reversed- phase ion-pair high-performance liquid chromatography显示文摘 | Mark D Roger CH | 1992 | Journal of Chromatography1992，579，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员