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| 1 | Multiple haploids, triploids, and tetraploids found in modern-day “living fossil” Ginkgo biloba显示文摘Ginkgo biloba,the last extant representative of a lineage of Mesozoic gymnosperms,is one of the few seed plants with an exceptionally long(~300 Myr)evolutionary history free of genome-wide duplications(polyploidy).Despite this genome conservatism,we have recently found a viable spontaneous tetraploid Ginkgo sapling during routine screening of several plants,demonstrating that natural polyploidy is possible in Ginkgo.Here we provide a much wider flow cytometry survey of ploidy in some European Ginkgo collections,and own seedlings(>2200 individuals and~200 cultivars).We found a surprisingly high level of ploidy variation in modern-day Ginkgo and documented altogether 13 haploid,3 triploid,and 10 tetraploid Ginkgo plants or cultivars,most of them being morphologically distinct from common diploids.Haploids frequently produced polyploid(dihaploid)buds or branches.Tetraploids showed some genome size variation.The surveyed plants provide a unique resource for future Ginkgo research and breeding,and they might be used to accelerate the modern diversification of this nearly extinct plant lineage. | PetrŠmarda Lucie Horová Ondřej Knápek Heidi Dieck Martin Dieck Katarína Ražná Pavel Hrubík Laszlo Orlóci Laszlo Papp Kristýna Veselá Pavel Veselý Petr Bureš | 2018 | Horticulture Research2018,5,1: | 4 |
| 2 | Hepatic progenitor cell activation in liver repair显示文摘The liver possesses an extraordinary ability to regenerate after injury.Hepatocyte-driven liver regeneration is the default pathway in response to mild-to-moderate acute liver damage.When replication of mature hepatocytes is blocked,facultative hepatic progenitor cells(HPCs),also referred to as oval cells(OCs)in rodents,are activated.HPC/OCs have the ability to proliferate clonogenically and differentiate into several lineages including hepatocytes and bile ductal epithelia.This is a conserved liver injury response that has been studied in many species ranging from mammals(rat,mouse,and human)to fish.In addition,improper HPC/OC activation is closely associated with fibrotic responses,characterized by myofibroblast activation and extracellular matrix production,in many chronic liver diseases.Matrix remodeling and metalloprotease activities play an important role in the regulation of HPC/OC proliferation and fibrosis progression.Thus,understanding molecular mechanisms underlying HPC/OC activation has therapeutic implications for rational design of anti-fibrotic therapies. | Adam Bria Jorgensen Marda Junmei Zhou Xiaowei Sun Qi Cao Bryon E.Petersen Liya Pi | 2017 | Liver Research2017,1,2: | 3 |
| 3 | Effect of immediate or delayed loading following immediate placement of implants with a modified surface显示文摘 | Linares A Mardas N Dard M Donos N | 2010 | Clin Oral Implants Res2010,,: | 1 |
| 4 | Alveolar ridge preservation with guided bone regeneration and a synthetic bone substitute or a bovine - derived xenograft: a randomized, controlled clinical trial 显示文摘 | Mardas N Chadha V Donosn N | 2010 | Clin Oral ImplantsRes2010,21,7: | 1 |
| 5 | Radiographic alveolar bonechanges following ridge preservation with two different biomaterials显示文摘 | Mardas N D'aiuto F Mezzomo L | 2011 | Clin Oral Implants Res2011,224,: | 1 |
| 6 | Stage-two surgery u- sing collagen soft tissue grafts: Clinical cases and uhrastruc- tural analysis 显示文摘 | Fischer KR Fickl S Mardas N | 2014 | Quintessence Int2014,45,10: | 1 |
| 7 | Carbon Dioxide Absorption During Laparoscopic Donor Nephrectomy: A Comparison Between Retroperitoneal and Transperitoneal Approaches显示文摘 | P.G. Kadam M. Marda V.R. Shah | 2008 | Transplantation Proceedings2008,,4: | 1 |
| 8 | Alveolar ridge preservation with guided bone regeneration and a synthetic bone substitute or a bo- vine-derived xenograft : a randomized, controlled clinical trial 显示文摘 | Mardas N Chadha V Donos N | 2010 | Clinical Oral Implants Res2010,21,7: | 1 |
| 9 | The use of human hypertrophic chondrocytes-derived extracellular matrix for the treatment of critical-size calvarial defects 显示文摘 | Donos N Graziani F Mardas N | 2011 | Clin Oral Implants Res2011,22,12: | 1 |
| 10 | The Use of Bromine Pentafluoride in the Extraction of Oxygen From Oxides and Silicates for Isotopic Analysis显示文摘 | Clayton TN Marda TK | 1963 | Geochim Cosmochim Acta1963,27,: | 1 |
| 11 | New Techniques for the Deinterleaving of Repeti- tive Sequence 显示文摘 | Marda H | 1989 | IEEE Proceedings on Radar and Signal Process1989,16,4: | 1 |
| 12 | Gentamicin used as an adjunct to GTR显示文摘 | Stavropaulos A Kostopoulos L Mardas N | 2003 | J Clin Periodontol2003,30,5: | 1 |
| 13 | Science park, a high tech fantasy?: an analysis of the science parks of Greece 显示文摘 | Bakouros Y L Mardas D C Varsakelis N C | 2002 | Technovation2002,,22: | 1 |
| 14 | Clinical outcomes of implants fol- lowing lateral bone augmentation: systematic assessment of availa- ble options ( barrier membranes, bone grafts, split osteotomy) 显示文摘 | Danos N Mardas N Chadha V | 2008 | J Clin Periodanto12008,35,8: | 1 |
| 15 | Characterization of cyanic flower colour of delphinium cultivars显示文摘 | HASHIMOTO F TANAKA M MARDA H | 2000 | J Jpn Soc Hortic Sci2000,69,4: | 1 |
| 16 | Changes in flower colouration and sepal anthocyanins of cyanic delphinium cultivars during flowering显示文摘 | HASHIMOTO F TANAKA M MARDA H | 2002 | Bioscience Biotechnology Biochemistry2002,66,8: | 1 |
| 17 | The effect of SLActive sur- face in guided bone formation in osteoporotic-like conditions 显示文摘 | Mardas N Schwarz F Petrie A | 2011 | Clin Oral Implants Res2011,22,4: | 1 |
| 18 | Science park, a high tech fantasy? Ananalysis of the science parks of Greece 显示文摘 | Bakouros Y L Mardas D C Varsakelis N C | 2002 | Technovation2002,22,2: | 1 |
| 19 | Science park,a high tech fantasy:an analysis of the science parks of Greece显示文摘 | BAKOUROS Y L MARDAS D C VARSAKELIS N C | | 0,,02: | 1 |
| 20 | Preparation and characterization of polypyrrole-tin oxide nanocomposite colloids 显示文摘 | ARMES S MARDA S P | 1995 | ChemMater1995,7,: | 1 |