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163篇 您的检索式：作者名="Manavalan"

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	题名	作者	年代	出处	被引量
1	Roles of toll-like receptors in Cancer: A double-edged sword for defense and offense显示文摘	Shaherin Basith Balachandran Manavalan Tae Yoo Sang Kim Sangdun Choi	2012	Archives of Pharmacal Research2012，，8：	3
2	Preparation and characterization of curcumin-piperine dual drug loaded nanoparticles显示文摘Objective:To prepare curcumin-piperine(Cu-Pi) nanoparticles by various methods and to study the effect of various manufacturing parameters on Cu-Pi nanoparticles and to identify a suitable method for the preparation of Cu-Pi nanoparticles to overcome oral bioavailability and cancer cell targeting limitations in the treatment of cancer.Methods:Cu-Pi nanoparticles were prepared by thin film hydration method,solid dispersion method,emulsion polymerization method and Fessi method.Optimization was carried out to study the effect of various manufacturing parameter on the Cu-Pi nanoparticles.Results:Out of four methods,Fessi method produced a minimum average particle size of 85.43 nm with a polydispersity index of 0.183 and zeta potential of 29.7 mV.Change of organic solvent(acetone or ethanol) did not have any significant effect on Cu-Pi nanoparticles.However,increase in sonication time,stirring speed,viscosity,use of 1:10:10 ratio of drag/polymer/surfactant,and use of anionic surfactant or combination of anionic surfactant with cationic polymer or combination of non-ionic surfactant with cationic polymer had a significant effect on Cu-Pi nanoparticles.Conclusions:Cu-Pi nanoparticles coated with PEC containing copolymer produced by Fessi method had a minimum average particle size,excellent polydispersity index and optimal zeta potential which fall within the acceptable limits of the study.This dual nanoparticulate drug delivery system appears to be promising to overcome oral bioavailability and cancer cell targeting limitations in the treatment of cancer.	C Moorthi Kiran Krishnan R Manavalan K Kathiresan	2012	Asian Pacific Journal of Tropical Biomedicine2012，2，11：	3
3	Hepatoprotective and antioxidant effects of Commiphora berryi (Arn) Engl bark extract against CCl 4 -induced oxidative damage in rats显示文摘	N.L. Gowri Shankar R. Manavalan D. Venkappayya C. David Raj	2008	Food and Chemical Toxicology2008，，9：	2
4	Physiological and molecular approaches to improve drought re- sistance in soybean显示文摘	Manavalan L P Guttikonda S K Tran L S	2009	Plant Cell Physiol2009，50，7：	1
5	Differentiation of human CD8 T cells:implications for in vivo persistence of CD8+ CD28-cytotoxic effector clones显示文摘	Posnett D N Edinger J W Manavalan J S	1999	Int Immunol1999，11，2：	1
6	Roles of toll-like recep- tors in cancer: a double-edged sword for defense and offense显示文摘	Basith S Manavalan B Yoo T H	2012	Arch Pharm Res2012，35，8：	1
7	Antibacterial activity of the leaf and stem bark extracts of a mangrove Rhizophora mucronata 显示文摘	Akalanka D Somaasundaram S T Manavalan R	2002	Seshaiyana2002，10，2：	1
8	RNAi-mediated disruption of squalene synthase improves drought tolerance and yield in rice 显示文摘	Manavalan LP Chen X Clarke J	2012	Journal of Experimental Botany2012，6，31：	1
9	Secretome analysis of ganoderma lucidum cultivated in sugarcane bagasse 显示文摘	Manavalan T Manawllan A Thangavelu K P	2012	Journal of Proteomics2012，77，：	1
10	Multicriteria decision making approach and experimental design as chemometric tools to optimize HPLC separation of domperidone and pantoprazole 显示文摘	Sivakumar T Manavalan R Muralidharan C	2007	J Pharm Biomed Anal2007，43，5：	1
11	iTRAQ-hased quantitative secretome analysis of Phanerochaete chrysosporium 显示文摘	Manavalan A Adav S S Sze S K	2011	J Proteomics2011，75，2：	1
12	Tolerization of dendritic cells by Ts cells:the crucial role of inhibitory receptors ILT3 and ILT4显示文摘	CHANG C C CIUBOTARIU R MANAVALAN J S	2002	Nat Immunol2002，3，：	1
13	Nanotherapeu- tics to overcome conventional cancer chemo therapy limit ations 显示文摘	Chidambararn M Manavalan R Kathiresan K	2011	J Pharm Pharmaceut Sci2011，14，1：	1
14	Molecular characterization of allospecific T suppressor and tolerogenic dendritic cells:review显示文摘	SUCIU-FOCA N MANAVALAN J S SCOTTO L	2005	Int Immunopharmacol2005，5，1：	1
15	High expression of ILT3 and ILT4 is a general feature of tolerogenic dendritic cells显示文摘	Manavalan JS Rossi PC Vlad G	2003	Transplant Immunol2003，11，34：	1
16	Parathyroid hormone stimulates circulating osteogenic cells in hypoparathyroidism显示文摘	Rubin MR Manavalan JS Dempster DW	2011	J Clin Endocrinol Metab2011，96，1：	1
17	Generation and function of antigen-specific suppressor and regulatory T cells显示文摘	SUCIU-FOCA N MANAVALAN J S CORTESINI R	2003	Transpl Immunol2003，11，34：	1
18	An improvement HPLC method with the aid of a chemometric protocol: Simultaneous analysis of Amlodipine and Atorvastatin in pharmaceutical formulations 显示文摘	SIVAKUMAR T MANAVALAN R MURALIDHARAN C	2007	J Sep Sci2007，30，：	1
19	Tolerization of den- dritic cells by T ( S ) cells : the crucial role of inhibitory receptors ILT3 and ILT4 显示文摘	Chang CC Ciubotariu R Manavalan JS	2002	Nat Immuno12002，3，3：	1
20	显示文摘	Chang CC Ciubotariu R Manavalan JS	2001	Nat Immunol2001，3，3：	1

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